ACC is a mucolytic and expectorant for the treatment of cough in children: a guide for mothers. Dosage and use of ACC for children Can children drink ACC?

Mucolytic drug

Active substance

Release form, composition and packaging

◊ (orange)

Excipients: sucrose - 2829.5 mg, - 12.5 mg, saccharin - 8 mg, orange flavor - 50 mg.

◊ Granules for the preparation of solution for oral administration (orange) white, homogeneous, without agglomerates, with the smell of orange.

Excipients: sucrose - 2717 mg, ascorbic acid - 25 mg, saccharin - 8 mg, orange flavor - 50 mg.

3 g - bags made of combined material (20) - cardboard packs.

◊ Syrup transparent, colorless, slightly viscous, with a cherry odor.

Excipients: methyl parahydroxybenzoate - 1.3 mg, sodium benzoate - 1.95 mg, disodium edetate - 1 mg, sodium saccharinate - 1 mg, sodium carmellose - 2 mg, sodium hydroxide (10% aqueous solution) - 30-70 mg, "Cherry" flavoring - 1.5 mg, purified water - 910.25-950.25 mg.

100 ml - dark glass bottles (1) complete with a measuring cup and a syringe for dosing - cardboard packs.

pharmachologic effect

Acetylcysteine ​​is a derivative of the amino acid cysteine. It has a mucolytic effect, facilitates the discharge of sputum due to a direct effect on the rheological properties of sputum. The action is due to the ability to break the disulfide bonds of mucopolysaccharide chains and cause depolymerization of sputum mucoproteins, which leads to a decrease in sputum viscosity. The drug remains active in the presence of purulent sputum.

It has an antioxidant effect due to the ability of its reactive sulfhydryl groups (SH groups) to bind to oxidative radicals and thus neutralize them.

In addition, acetylcysteine ​​promotes the synthesis of glutathione, an important component of the antioxidant system and chemical detoxification of the body. The antioxidant effect of acetylcysteine ​​increases the protection of cells from the damaging effects of free radical oxidation, which is characteristic of an intense inflammatory reaction.

With the prophylactic use of acetylcysteine, there is a decrease in the frequency and severity of exacerbations in patients with chronic bronchitis and cystic fibrosis.

Pharmacokinetics

Suction and distribution

Absorption is high. Bioavailability when taken orally is 10%, which is due to the pronounced “first pass” effect through the liver. The time to reach Cmax in the blood is 1-3 hours.

Binding to blood plasma proteins - 50%. Penetrates through the placental barrier. There are no data on the ability of acetylcysteine ​​to penetrate the BBB and be excreted in breast milk.

Metabolism and excretion

Rapidly metabolized in the liver to form a pharmacologically active metabolite - cysteine, as well as diacetylcysteine, cystine and mixed disulfides.

Excreted by the kidneys in the form of inactive metabolites (inorganic sulfates, diacetylcysteine). T 1/2 is about 1 hour.

Pharmacokinetics in special clinical situations

Impaired liver function leads to an extension of T1/2 to 8 hours.

Indications

- diseases of the respiratory system, accompanied by the formation of viscous, difficult to separate sputum (acute and chronic bronchitis, obstructive bronchitis, tracheitis, laryngotracheitis, pneumonia, lung abscess, bronchiectasis, bronchial asthma, COPD, bronchiolitis, cystic fibrosis);

— acute and chronic sinusitis;

- otitis media.

Contraindications

- peptic ulcer of the stomach and duodenum in the acute phase;

- hemoptysis;

- pulmonary hemorrhage;

- pregnancy;

- lactation period (breastfeeding);

- children under 2 years of age;

- fructose intolerance, because the drug contains sorbitol (granules for oral solution /orange/ 100 mg and 200 mg);

- sucrase/isomaltase deficiency, glucose-galactose deficiency (granules for oral solution /orange/ 100 mg and 200 mg);

- hypersensitivity to acetylcysteine ​​and other components of the drug.

Carefully the drug should be used in patients with a history of gastric and duodenal ulcers; for bronchial asthma, obstructive bronchitis; liver and/or kidney failure; histamine intolerance (long-term use of the drug should be avoided, since acetylcysteine ​​affects the metabolism of histamine and can lead to signs of intolerance, such as headache, vasomotor rhinitis, itching); varicose veins of the esophagus; diseases of the adrenal glands; arterial hypertension.

Dosage

Granules for oral solution (orange) 100 mg and 200 mg

It is recommended to prescribe the drug 200 mg (2 sachets of ACC 100 mg or 1 sachet mg) 2-3 times a day. Daily dose - 400-600 mg.

It is recommended to take 100 mg (1 sachet of 100 mg) 3 times/day or 200 mg (2 sachets of ACC 100 mg) 2 times/day, or 1/2 sachet of ACC 200 mg 3 times/day or 1 sachet of ACC 200 mg 2 times/day. Daily dose - 300-400 mg.

It is recommended to take the drug 100 mg (1 sachet of ACC 100 mg or 1/2 sachet of ACC 200 mg) 2-3 times a day. Daily dose - 200-300 mg.

At cystic fibrosis It is recommended to take the drug 200 mg (2 sachets of ACC 100 mg or 1 sachet of ACC 200 mg) 3 times a day. Daily dose - 600 mg.

Children aged 2 to 6 years- 100 mg (1 sachet of ACC 100 mg or 1/2 sachet of ACC 200 mg) 4 times a day. Daily dose - 400 mg.

Patients with body weight ≥30 kg for cystic fibrosis, if necessary, you can increase the dose to 800 mg/day.

At Duration of treatment is 5-7 days. At

The drug is taken orally after meals. Additional fluid intake enhances the mucolytic effect of the drug.

ACC in the form of granules for oral solution (orange) 100 mg and 200 mg are dissolved in water, juice or iced tea.

Syrup

Adults and teenagers over 14 years old Prescribe 10 ml of syrup 2-3 times a day (400-600 mg acetylcysteine).

Children aged 6 to 14 years- 5 ml of syrup 3 times/day or 10 ml of syrup 2 times/day (300-400 mg of acetylcysteine).

Children aged 2 to 5 years Prescribe 5 ml of syrup 2-3 times a day (200-300 mg acetylcysteine).

At cystic fibrosischildren over 6 years old it is recommended to take the drug 10 ml of syrup 3 times a day (600 mg acetylcysteine); children aged 2 to 6 years- 5 ml of syrup 4 times a day (400 mg of acetylcysteine).

At short-term colds Duration of treatment is 4-5 days. At chronic bronchitis and cystic fibrosis the drug should be used for a longer period of time to prevent infections. For long-term illnesses, the duration of therapy is determined by the attending physician.

The drug is taken orally after meals. Additional fluid intake enhances the mucolytic effect of the drug.

ACC syrup is taken using a measuring syringe or measuring cup contained in the package. 10 ml of ACC syrup corresponds to 1/2 measuring cup or 2 filled syringes.

Using a measuring syringe

1. Open the bottle cap by pressing on it and turning it counterclockwise.

2. Remove the cap with the hole from the syringe, insert it into the neck of the bottle and press in until it stops. The stopper is designed to connect the syringe to the bottle and remains in the neck of the bottle.

3. It is necessary to insert the syringe tightly into the stopper. Carefully turn the bottle upside down, pull the syringe plunger down and draw the required amount of syrup (ml). If air bubbles are visible in the syrup, press the plunger all the way and then refill the syringe. Then return the bottle to its original position and remove the syringe.

4. The syrup from the syringe should be poured onto a spoon or directly into the child’s mouth (into the cheek area, slowly, so that the child can swallow the syrup). While taking the syrup, the child should be in an upright position.

5. After use, rinse the syringe with clean water.

Side effects

According to WHO, undesirable effects are classified according to their frequency of development as follows: very often (≥1/10), often (≥1/100,<1/10), нечасто (≥1/1000, <1/100), редко (≥1/10 000, <1/1000) и очень редко (<10 000), частота неизвестна (частоту возникновения нельзя определить на основании имеющихся данных).

Allergic reactions: uncommon - skin itching, rash, exanthema, urticaria, angioedema; very rarely - anaphylactic reactions up to shock, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell's syndrome).

From the respiratory system: rarely - shortness of breath, bronchospasm (mainly in patients with bronchial hyperreactivity in bronchial asthma).

From the cardiovascular system: infrequently - decreased blood pressure, tachycardia.

From the digestive system: uncommon - stomatitis, abdominal pain, nausea, vomiting, diarrhea, heartburn, dyspepsia.

On the part of the hearing organ: infrequently - tinnitus.

Other: rarely - headache, fever; in isolated cases - the development of bleeding as a manifestation of a hypersensitivity reaction, a decrease in platelet aggregation.

Overdose

Acetylcysteine ​​when taken at a dose of 500 mg/kg/day does not cause signs and symptoms of overdose.

Symptoms: In case of an erroneous or intentional overdose, phenomena such as diarrhea, vomiting, stomach pain, heartburn, and nausea are observed.

Treatment: carrying out symptomatic therapy.

Drug interactions

With the simultaneous use of acetylcysteine ​​and antitussives, sputum stagnation may occur due to suppression of the cough reflex.

With the simultaneous use of acetylcysteine ​​and oral antibiotics (penicillins, cephalosporins and others), the latter may interact with the thiol group of acetylcysteine, which can lead to a decrease in antibacterial activity. Therefore, the interval between taking antibiotics and acetylcysteine ​​should be at least 2 hours (except for cefixime and loracarbef).

Concomitant use with vasodilators can lead to an enhanced vasodilator effect.

special instructions

For bronchial asthma and obstructive bronchitis, acetylcysteine ​​should be prescribed with caution under systematic monitoring of bronchial patency.

Severe allergic reactions such as Stevens-Johnson syndrome and Lyell's syndrome have been very rarely reported with the use of acetylcysteine. If changes in the skin and mucous membranes occur, the patient should immediately stop taking the drug and consult a doctor.

When dissolving the drug, it is necessary to use glass containers and avoid contact with metals, rubber, oxygen, and easily oxidized substances.

You should not take the drug immediately before bedtime (the preferred time of administration is before 18.00).

When prescribing the drug to patients on a diet aimed at limiting sodium intake, it is necessary to take into account that 1 ml of ACC syrup contains 41.02 mg of sodium.

There is no need for special precautions when disposing of unused ACC drug.

Instructions for patients with diabetes mellitus

When treating patients with diabetes, it is necessary to take into account that ACC in the form of granules for the preparation of oral solution (orange) 100 mg and 200 mg contains sucrose.

ACC in the form of granules for the preparation of a solution for oral administration /orange/ 100 mg and 200 mg: 1 sachet of 100 mg corresponds to 0.24 XE, 1 sachet of 200 mg - 0.23 XE.

Impact on the ability to drive vehicles and operate machinery

There is no information on the effect of the drug on the ability to drive vehicles and engage in other potentially hazardous activities that require increased concentration and speed of psychomotor reactions.

Pregnancy and lactation For liver dysfunction

The drug should be taken with caution used for liver failure.

Conditions for dispensing from pharmacies

The drug is available without a prescription.

Storage conditions and periods

The drug should be stored out of the reach of children at a temperature not exceeding 25°C.

The shelf life of granules for preparing a solution for oral administration (orange) is 4 years.

The shelf life of the syrup is 2 years; After opening, the bottle should be stored for no more than 10 days at a temperature not exceeding 25°C.

When a child falls ill in the family, all the attention of adults focuses on him. And the point here is not whether it is a serious illness or a cold with a cough. Moreover, in fact, cough itself is a symptom of the disease and requires treatment.

To combat this problem, a wide variety of medicines have been developed in a variety of forms: tablets, suspensions, formulations for inhalation, “ACC” for children was developed by manufacturers in Germany and Slovenia. The main functions of this drug are to dilute difficult-to-separate mucus and facilitate the process of removing it from the respiratory tract. "ACC" has an anti-inflammatory effect, suppressing pathogens that develop in sputum.

Operating principle of "ACC"

For the stable functioning of the human body, nature has arranged everything in such a way that a special mucous secretion is constantly produced in the respiratory tract, the main functions of which include protective, cleansing and antibacterial effects. If a person gets sick, the process of producing this secretion is activated many times over. The consistency of this mucus has increased viscosity: the child suffers from prolonged coughing attacks, suffocates, and the sputum does not come out. This cough is called non-productive.

It is in such cases that “ACC” for children (syrup) is prescribed to help the child’s body. Instructions for use allow it to be prescribed to children from the age of two. The viscosity of sputum directly depends on the presence of special bonds in it - disulfide bridges. "ACC", entering the child's body, affects these connections and contributes to their rupture. The sputum becomes less viscous, and the process of removing it from the respiratory tract is greatly facilitated. Air masses entering the bronchi are able to circulate freely without causing irritation to the nerve endings. The cough becomes productive.

"ACC" (syrup for children) continues to remain active even in cases where there is a purulent component in the sputum. At first, parents may feel that the cough has gotten worse. However, the intensification of this process only indicates that the drug is working. Gradually the cough reflex fades, and soon the cough goes away completely.

The antioxidant properties of "ACC" are able to suppress local inflammatory processes, which practically eliminates the likelihood of relapses and complications. The medication has no effect on the immune system.

Possible release forms

Manufacturers, for convenience and breadth of use, offer the drug in several release forms. The granules in the bottle are diluted with water on their own to form an “ACC” syrup. Instructions for use for children often allow even children who have not yet reached the age of two to be treated with this medicine. True, doctors do not practice prescribing it to newborns for the treatment of cough and bronchitis for the reason that the airways of infants are very narrow and the pectoral muscles are still weak. For these reasons, a small child simply will not be able to cough up the increased volume of sputum. If there is no alternative to this medication, then treatment with ACC should be carried out under the supervision of the treating doctor.

However, it should be noted that “ACC” (syrup) instructions for use for children under one year old allow it to be prescribed if there is a hereditary disease characterized by impaired functioning of the respiratory system.

Effervescent tablets "ACC" are widely used. They can be purchased in three dosages: 100, 200 and 600 mg of acetylcysteine ​​(the main active ingredient). A dose of 600 mg bears the trade name “ACC-Long”, is characterized by a prolonged effect and is prescribed to patients at least 14 years of age. One tablet of this medication, taken once, replaces several smaller doses.

The suspension is prepared by diluting granules from sachets (100, 200 mg) in water, tea, milk or juice. The resulting composition should not be hot. Ideally, its temperature is close to body temperature.

With the use of "ACC" it is even possible to do inhalations. 1-2 ml of a solution intended for injection (used in very severe cases in a hospital setting under the supervision of a physician) is mixed with sodium chloride and used in special inhalers or nebulizers. Procedures can be performed 1-2 times a day. The course of therapy is up to 10 days.

Indications for use

The indications for which this drug can be prescribed are quite wide. As for small patients, a special dosage has been developed for them, called “ACC 100”. Instructions for children: syrup (as the optimal form for treating even infants and children under 2 years old) can be used for a number of diseases of the respiratory system.

In general, “ACC” is prescribed to patients suffering from bronchitis (any form: chronic, acute, obstructive), pneumonia, tracheitis, broncholitis (inflammatory processes of the lower respiratory tract), cystic fibrosis. The medication is used for bronchiectasis (an increase in the diameter of the bronchi in the place where the bronchial wall is damaged).

It is also practiced to prescribe "ACC" in the treatment of otitis and sinusitis (acute, chronic form), since the drug is able to dilute not only sputum, but also accumulations of pus, stimulating its removal from the body.

Contraindications for taking "ACC"

"ACC" for children (syrup) instructions for use prohibits use by patients with individual intolerance to the components of the medication and those who suffer from gastric and duodenal ulcers (acute stage). The same diseases, but in remission, can also respond to the use of ACC. Therefore, patients with such problems should be attentive to their well-being.

With great precautions, "ACC" (syrup for children) should be taken by patients with kidney and liver failure, problems with the adrenal glands, and bronchial asthma.

Since many diseases have become younger today, even young children can encounter gastrointestinal ulcers or diabetes mellitus. With the latter disease, it must be borne in mind that “ACC” contains sucrose. If a child is diagnosed with phenylketonuria, then for the treatment of cough it is necessary to choose “ACC”, which does not include aspartame (sweetener).

Contraindication for "ACC Long" is a child under 14 years of age.

Directions for use and dosage

Instructions for use of "ACC 100" for children are recommended for use when the patient's age is from 2 to 5 years. It can also be granules in sachets (volume - 100 mg), which are taken 2-3 times a day. Another option is granules in a bottle for making syrup, which is indicated for taking 5 ml (1 measuring spoon) also 2-3 times during the day after meals.

Patients in the age group from 6 to 14 years old are prescribed ACC 200 mg (granules in bags) twice a day or 2 (10 ml) syrup twice a day with meals.

For patients over 14 years of age, it is practiced to prescribe "ACC" 2 scoops (10 mg) 2-3 times a day (or use "ACC Long").

In the most extreme cases, the instructions for use for children up to one year allow the use of “ACC” (syrup). Reviews from doctors in this case indicate an underdeveloped respiratory system and weak pectoral muscles. A small child may have difficulty coughing up the increased volume of mucus.

It is worth saying that the standard treatment regimen is described above. In some particularly severe cases, the dosage of the drug can be adjusted upward (or decreased, if the situation is not very severe). The usual course of treatment is up to 7 days. Only the doctor can decide to increase the treatment period. In chronic forms of bronchitis or cystic fibrosis, the course of therapy using ACC can last for several months. In parallel with this, constant monitoring of the functioning of the liver, kidneys, and adrenal glands is carried out. Blood enzyme levels are also subject to monitoring.

Possible side effects

The drug "ACC" causes side effects quite rarely. Parents of young patients talk about the appearance of headaches, the development of stomatitis, and tinnitus. Deviations in the functioning of the gastrointestinal tract, such as nausea, vomiting, and diarrhea, occur much less frequently.

Also, among the possible negative manifestations in the process of using “ACC” for children (syrup), the instructions for use indicate the risk of lowering blood pressure, the development of tachycardia (rapid heartbeat), bronchospasms, and the appearance of urticaria.

If any negative reactions occur during therapy using ACC, you must stop taking the medication and contact your pediatrician without fail.

Exceeding the permissible dosage

An overdose of the drug "ACC" can occur in several cases. It is possible for a child to take a dose calculated for an adult patient, use the medication in an excessive amount without special instructions from a doctor, or accumulate it (“ACC”) in the body, which is possible with a long course of treatment without proper monitoring of the condition of the liver, kidneys, and blood counts. In any case, the possible reactions of patients to “ACC” (for children - syrup), the instructions for use describe such manifestations as a drop in blood pressure, nausea, vomiting, and a feeling of dry mouth. There is also a possibility of allergic dermatitis, accompanied by a rash and itchy skin, and bronchospasm may develop.

In especially severe cases, doctors talk about the possibility of angioedema and shock.

Interaction with other drugs

All information about possible drug interactions is contained in the instructions for use for “ACC” (syrup). For children over one year of age, it can be taken only in the most extreme cases and under the supervision of a doctor. Although, when used in parallel with ACC, there is a danger for patients of any age.

There is information about the incompatibility of the main active ingredient “ACC” with semisynthetic penicillins, cephalosporins, and aminoglycosides. On the contrary, there is no information about the incompatibility of acetylcysteine ​​with such antibacterial drugs as Amoxicillin, Erythromycin and Cefuroxime.

What should you pay attention to?

As mentioned earlier, for the treatment of patients from 2 to 5 years of age, doctors usually prefer the drug “ACC 100” (syrup). Instructions for use for children, reviews of children's doctors warn parents about the inadmissibility of taking “ACC” and any antitussive medications together. With this parallel use, "ACC" thins the sputum, and suppresses the cough reflex, the sputum is not coughed up. This is fraught with stagnation of sputum, which seriously threatens the health and sometimes the life of the child.

Pediatricians also do not prescribe ACC together with antibacterial agents, since they may be incompatible. Only a few types of antibiotics of the tetracycline, penicillin and cephalosporin series can be used together with ACC with intervals of at least 2 hours between doses.

It is permissible to dilute ACC granules and powders yourself only in glass containers. It is recommended to avoid contact with rubber or metal.

When treating with ACC, it is necessary to increase the volume of fluid consumed. This will significantly enhance the mucolytic effect of the drug. Children should take ACC no later than 4 hours before bedtime.

Consumer opinion about the medicine

The patients' parents are satisfied with the drug "ACC" (syrup). Instructions for use for children (consumer reviews confirm this fact) give clear instructions on the method of use of the drug and dosage. Cough in children usually becomes productive very quickly and goes away within 3-4 days. That is, the product is effective in almost 100% of cases of use.

The syrup has a pleasant orange flavor, so even the most capricious patients do not have to be forced to take the medicine for a long time. In addition, the cost of “ACC” is available to a wide range of consumers with very different levels of financial capabilities. The product is very convenient to store; it will not be difficult to take it with you on the road.

ACC, of ​​course, has certain contraindications and side effects, but using it only as prescribed by the attending physician and following all recommendations will eliminate most of the unpleasant consequences and manifestations.

The child will breathe deeply and calmly, and parents will not worry about his well-being.

Children suffer from diseases more difficult than adults. Therefore, when the baby catches a cold, parents do everything to quickly cope with the disease and get rid of the symptoms. ARI is often accompanied not only by fever and runny nose, but also by a strained cough, during which it is impossible to clear the throat. To ease breathing, sore throat and give the patient the opportunity to sleep, it is recommended to purchase ACC for children.

A lingering cough is often found in children suffering from acute respiratory infections. The child cannot clear his throat and strains his throat in fruitless attempts. Parents do not always competently approach the choice of a remedy that will relieve symptoms and remove phlegm. To stop and eliminate the spread of pathogenic bacteria in the respiratory system, doctors advise giving the patient ACC for children.

Release form

This cough medicine can be bought at the pharmacy in several forms - powder, effervescent tablets and syrup. Briefly about each form and recommendations in which case to use them.

Powder (granules)

ACC - granules (powder) are sold in bags for single use. There is a dosage of 100 (see instructions for using ACC 100 powder for children below) or 200 grams (cost from 130 to 150 rubles for 20 packets). They are diluted with water. The product has different fruit flavors, so children drink it with pleasure.

Effervescent tablets

No less popular are ACC Long effervescent tablets, which are also sold in several dosages - 100 and 200 grams. They are thrown into a container of water and wait until a suspension forms. The solution, in addition to the flavored taste and smell indicated in the description, may have a slight sulfuric odor. Price – from 200 to 250 rubles per pack.

Syrup

It is a clear liquid with a fruity taste and smell. ACC syrup is sold in a darkened glass bottle. The bottle cap is made so that only an adult can open it.

Inhalations

For children from six to 14 years of age, in particularly problematic cases, inhalations are prescribed, which can only be carried out under the supervision of a specialist in a hospital. One to two milliliters of the drug is diluted with a special solution. The course of treatment is a maximum of twice a day for no more than 10 days.

There are also ampoules for injection.

Compound

Some components differ in different release forms, but there is a component common to all - acetylcysteine ​​(derived from the amino acid cysteine) in a certain dose. The “fizzy drinks” contain carboxylic and ascorbic acid, a sugar substitute, sodium salt, bicarbonate, mannitol, lactose, and flavoring agents.

Ingredients: water, carmellose, methyl parahydroxybenzoate, synthetic sweetener, sodium and disodium salt, flavorings, ascorbic acid, sugar and saccharin - all these substances are contained in ACC syrup for children. The instructions for use also include these names.

In a healthy state, mucus should constantly accumulate in the respiratory passages. It is needed to protect the bronchi from infections and protect them. During illness, this mucus is produced in increased quantities because the body gets rid of pathogenic bacteria. In large quantities, mucus becomes phlegm.

When there is too much mucus, it is difficult to cough up, especially for children. Stagnant sputum can become a good breeding ground for microorganisms, which can lead to complications. ACC thins mucus, makes it less viscous, relieves inflammation, and makes it possible to remove mucus. When the sputum is removed, air begins to circulate easily through the bronchi without affecting the nerve endings.

Don't be alarmed if your cough gets worse at first - this is normal. This means that the medicine has started to work and the cough will soon go away. Antioxidant properties eliminate inflammation and prevent complications from developing.

When can a doctor prescribe ACC?

As a rule, the medication is prescribed to children who have been diagnosed with respiratory tract diseases. But there are other indications:

• pneumonia;
• cystic fibrosis;
• tracheitis;
• bronchiecstasis;
• laryngitis;
• sinusitis;
• abscess in the lungs;
• sinusitis (will help clear snot from your nose)
• prevention of complications after respiratory diseases.

To correctly determine the course of treatment, you need the doctor to listen to the complaints and conduct an examination. The drug is prescribed depending on the types of cough: dry, wet, single and paroxysmal.

At what age can you drink?

Can be given to children up to two years old. But since their respiratory system is not yet properly developed, it can only be taken with a prescription and in the presence of a doctor, because the baby may not be able to cope with the amount of mucus and will not cough it up.

It is forbidden to give to children under one year old!

There are both general contraindications for all forms, and additional ones for each of them.

For all forms:

• intolerance to individual components;
• stomach or duodenal ulcer;
• pregnancy and feeding time.

If the child does not tolerate histamine, then drinking ACC for a long time is not recommended. You should drink with caution if you have bronchial asthma, bronchitis and pathology of the esophageal veins, patients with adrenal glands, hypertension, and impaired renal function.

Contraindications for effervescent tablets:

• glucose-galactose loss in the body;
• lactose intolerance;
• children under two years old.

Taking granules is not possible if:

• glucose-galactose deficiency;
• lack of sucrase;
• under six years of age;
• fructose intolerance.

Pregnancy and breastfeeding

At the moment, it is not known for sure whether it is safe to be treated with medication during pregnancy, therefore, in order not to risk it, it is not recommended for women waiting for replenishment. However, sometimes a doctor may prescribe the drug for all trimesters. It is also not recommended to take the medication while breastfeeding.

If this is absolutely necessary, lactation is stopped during treatment, since during breastfeeding the drug can enter the baby’s body, which can cause negative consequences, especially in newborns.

Side effects

Adverse reactions occur very rarely in children. It could be:

• nausea;
• allergy;
• abdominal pain;
• bloating;
• heartburn;
• dizziness;
• tinnitus and difficulty coordinating;
• decrease in vascular pressure (temporarily).

Very rarely, bleeding may occur.

Instructions

When treating with any drug, it is very important to follow the instructions.

How to use

ACC is given to children after meals. During recovery, it is recommended to give the baby more fluids to drink and ensure that the rooms are clean and have the right level of humidity. This will help your recovery. In addition, drinking alkaline mineral waters will bring additional benefits.

The course of treatment usually does not exceed seven days.

The famous children's doctor Komarovsky advises: if the child categorically refuses to take the syrup, then it can be diluted in a small amount of his usual liquid - water or compote.

Children from two to five years old are given either 100 mg (see ACC powder for children instructions for use), or 1 scoop of prepared syrup several times a day.

Children from six to 14 years old - 200 mg or two tablespoons of syrup twice a day.

Overdose

Taking a larger dose occurs if:

• the medicine is used without consultation with a specialist in an increased dose;
• long-term use of a drug that accumulates in the body.

Overdose reaction:

• pressure drop;
• nausea, vomiting;
• intestinal disorder;
• stomach ache;
• skin rashes;
• bronchospasm.

Give the patient exactly as much medicine as he is supposed to, do not exceed the dosage yourself!

Parallel use with other medications

The medication should not be used with antibiotics such as penicillins or aminoglycoside anitbiotics. There is no information that the medicine is incompatible with antibacterial drugs.

You should not give several cough remedies at once - this can cause a lack of cough and stagnation of sputum.

Simultaneous use of children's ACC with antibiotics will lead to the fact that the antibacterial effect of the syrup will decrease. The interval between the use of two drugs should be at least 120 minutes.

It is impossible to prepare the solution in a metal container so that it does not oxidize.

The last dose of medication is no later than 18:00. It is not recommended to give syrup at night.

How and how much to store

Despite the fact that the manufacturers made sure that the child could not open the bottle on his own, it is recommended to store the medicine away from children. The optimal temperature is up to 25 degrees inclusive. Before the packaging is sealed, the drug can be stored for 2 years. Once you open it, the shelf life is reduced to 10 days.

Analogues of ACC

No matter how popular this remedy is, it has substitutes that, as a rule, are not inferior in medicinal properties. The active substance in them is also acetylcysteine. Fluimicil and Acestad occupy second and third positions after syrup. Their prices are approximately the same.

In addition to them, other mucolytic drugs are considered analogues. For example, Ambroxol, Acestine, Acetylcysteine, Bromhexine. But before taking these medications, you should carefully study the instructions or consult a doctor - their effects on the body and contraindications differ from ACC.

Do not replace one drug with another on your own, do not give medications without a doctor’s prescription!

Since children's immunity is not sufficiently developed, coughing is a fairly common occurrence in children. For parents who are faced with this problem, many experts recommend using the drug ACC 100 to treat children. This is one of the most well-known drugs that has a mucolytic, expectorant effect and is used to dilute sputum in diseases of the respiratory system, accompanied by the formation of a viscous secretion. ACC 100 for children is available in two forms - powder in a bag for preparing an oral solution and granules in a bottle for preparing syrup. The last of the above is a specially developed pediatric form of the drug, which is approved for use by infants and up to 2 years of age.

ACC 100 for children - application

This drug is prescribed in all cases of diseases with the accumulation of thick viscous sputum in the upper respiratory tract and bronchial tree:

• bronchitis;
• bronchiectasis;
• bronchiolitis;
• laryngotracheitis;
• bronchial asthma;
• COPD;
• pneumonia;
• sinusitis;
• pulmonary cystic fibrosis;
• otitis;
• prevention of complications during operations on the respiratory organs.

How to take ACC 100?

During treatment, it is important to observe the dosage of the drug ACC 100, depending on the age category of the patient.

1. Infants from the 10th day of life and children under 2 years of age are prescribed 50 mg of medication or 2.5 ml of syrup 2-3 times a day.
2. For children aged 2 to 6 years, the daily dose is 200-300 mg of the drug in 2-3 doses.
3. The permissible maximum for children from 6 to 14 years of age is 400 mg per day, also divided into 2-3 doses.
4. For patients over 14 years of age, ACC 100 is prescribed in a daily dose of 400-600 mg.

This drug must be taken after meals. It is also important to ensure that your child drinks enough fluids throughout the day. The full course of treatment with ACC 100 should not exceed 7 days, and in severe cases, the duration of treatment is determined by the attending physician.

How to dilute ACC 100?

It is necessary to prepare the medicine according to the instructions given in the instructions:

• to prepare the syrup, add boiled water at room temperature to the indicated mark in the bottle and shake well; It should be noted that the prepared syrup can be stored in the refrigerator for no more than 12 days;
• To prepare the solution, the contents of one sachet must be dissolved in 100 ml of cold liquid (water, compote, juice).

ACC 100 - contraindications and side effects

Like all medications, ACC 100 for children has a number of contraindications:

For children in the first year of life, ACC 100 is prescribed only when necessary and under the strict supervision of a doctor, since this drug contains excipients that are not very useful for infants.

Be careful when using the medicine for the first time, as it may cause some side effects: vomiting, nausea, diarrhea, heartburn, noise and ringing in the ears, inflammation of the oral mucosa, headaches, itching of the skin, urticaria, tachycardia, bronchial spasms.

Good health to you and your children, but if your child has developed a painful cough, try not to resort to self-medication, but hurry up and consult a specialist.

When is ACC used for children?

This drug is used in all cases when a lot of viscous mucus is formed in the respiratory tract: sputum in the bronchi with bronchitis, tracheitis, bronchiolitis (inflammation of the small bronchi), pneumonia (pneumonia), cystic fibrosis (a hereditary disease that is accompanied by the release of large amounts of mucus), lung abscess (the so-called cavity filled with pus), laryngotracheitis (inflammation of the larynx and trachea), bronchial asthma.

In addition, mucus also appears in the upper respiratory tract during otitis (inflammation of the middle ear), sinusitis (inflammation in the sinuses of the skull bones, including sinusitis).

What substance is included in the drug and how does it work?

The active ingredient "ACC" is acetylcysteine. Mucus, including sputum, has a viscous consistency due to the content of long molecules that are also connected by bridges of sulfur atoms.

Acetylcysteine ​​destroys these bridges, the molecules become smaller, and the mucus becomes more fluid and easier to leave the respiratory tract. Sometimes due to the action of the drug, there is much more sputum.

In addition, “ACC” neutralizes active substances (free radicals) that are released during inflammation and damage the tissues of the respiratory tract. As a result, the drug has an anti-inflammatory effect.

ACC for children: how is it taken?

The drug is available in the form of effervescent tablets and solution (it can be used for inhalation). For children under 6 years of age, the medicine is given in the form of syrup (it is sold in a bottle in the form of granules, and the syrup is obtained by adding water).

"ACC" must be diluted in a glass container and avoid contact with metals and rubber, because the drug reacts to these substances. Dosage of the drug: children under 2 years old – 100 mg 2 times a day; children 2-6 years old - 200 mg 2 times a day or 100 mg 3 times in the form of water-soluble granules; patients 6-14 years old - 200 mg 2 times a day.

For chronic diseases, when the medicine needs to be taken for several weeks, it is prescribed as follows: children 2-14 years old - 100 mg 3 times a day; for cystic fibrosis, children from 10 days to 2 years - 50 mg 3 times a day, children 2-6 years old - 100 mg 4 times, patients over 6 years old - 200 mg 3 times a day in the form of water-soluble granules, effervescent tablets or capsules.

You can do inhalations with a solution of the drug. For aerosol therapy in ultrasound devices, you need to spray 20 ml of a 10% solution or 2-5 ml of a 20% solution. The duration of inhalation is 15-20 minutes, the frequency is 2-4 times a day. The medicine is also instilled into the external auditory canal and nasal passages at a dose of 150-300 mg (per 1 procedure).

Contraindications and side effects

"ACC" should be used only as prescribed by a doctor, because it cannot be combined with certain other drugs (for example, drugs that suppress the cough reflex). You need to understand what is happening in the child’s lungs, and whether thinning the sputum will lead to undesirable consequences, since it will not be able to come out. Only a specialist can assess the situation.

For bronchial asthma, the drug is used with caution. The medicine may cause the following side effects: nausea, vomiting, feeling of fullness in the stomach, nosebleeds, hives, tinnitus, drowsiness, fever, heartburn.

In case of phenylketonuria (a hereditary disease that is detected in the maternity hospital and requires the exclusion of foods containing phenylalanine from the child’s diet), you need to choose those forms of “ACC” that do not contain the sweetener aspartame, because with this disease it is not processed by the body. When treating patients with diabetes, it is necessary to take into account that the granules contain sugar.