Grippostad rhino nasal drops instructions. Directory of medicines. Release form, composition and packaging
Grippostad Reno used as a decongestant for acute, infectious, allergic (vasomotor) rhinitis. Xylometazoline, an imidazoline derivative, is an alpha2-adrenergic mimetic agent. Its vasoconstrictive effect causes the removal of congestion in the nasal mucosa. The onset of action is usually observed after 5 - 10 minutes: nasal breathing is facilitated by reducing mucosal congestion and improving secretion drainage.
Xylometazoline is an imidazoline derivative, an α-adrenergic sympathomimetic. Directly stimulates α-adrenergic receptors and constricts blood vessels. When applied topically, it reduces swelling of the nasopharyngeal mucosa and hyperemia. Restores the patency of the nasal passages and facilitates nasal breathing by decongesting the mucous membrane and improving the drainage of secretions.
The drug begins to act within 5-10 minutes and the effect lasts for several hours (on average 6-8 hours).
When used intranasally, the amount of the drug that is absorbed can sometimes be sufficient to develop systemic effects, for example, on the central nervous system and the cardiovascular system.
Indications for use
Grippostad Reno spray indicated for acute rhinitis of any etiology, including infectious, allergic (vasomotor) rhinitis.
Grippostad Rino 0.1% drops for adults and the spray is intended for adults and school-age children.
Drops for children 0.05% Designed for children 2 - 6 years of age.
Mode of application:
Adults and school-age children - 1-2 Grippostad Reno drops or 1 full pump into each nostril up to three times a day as needed.
For children 2 - 6 years of age, drops for children 0.5% are dripped 1 - 2 drops into each nasal passage three times a day if necessary.
Duration of use - no more than 3-5 days.
Side effects:
Respiratory system Grippostad Reno may, especially in sensitive patients, cause a temporary, mild burning sensation or dryness of the nasal mucosa. There are reports of transient swelling (reactive hyperemia) of the nasal mucosa after the cessation of the effect of xylometazoline. Long-term, frequent and/or use of xylometazoline in high doses can cause burning and dryness of the nasal mucosa, as well as reactive edema with drug-induced rhinitis.
This effect can be observed only after 5 - 7 days of therapy with continuous use of the drug. Nervous system Rare cases of headache, insomnia or fatigue have been observed. Cardiovascular system Local intranasal use may, in extremely rare cases, lead to systemic sympathomimetic effects such as palpitations, increased pulse rate or increased blood pressure. Effects on the ability to drive machines and vehicles Long-term, frequent and/or high-dose use of drugs containing xylometazoline, as a rule, does not have an effect on the nervous system. If this is observed, the ability to drive a car or operate machinery may be impaired.
Contraindications
Grippostad Reno should not be used in patients with: hypersensitivity to any ingredient of Grippostad Rino; atrophic rhinitis.
Grippostad Rino (drops for adults) and spray should not be used in children under 6 years of age. Grippostad Rino contains benzalkonium chloride and should therefore not be used in patients with known hypersensitivity to this preservative.
Grippostad Rhino should only be used after a thorough assessment of the pros and cons of the possible risks in: patients receiving monoamine oxidase inhibitors (MAOIs) or other drugs that potentially increase blood pressure; patients with glaucoma, narrow-angle glaucoma; patients with various cardiovascular diseases (for example, coronary heart disease, arterial hypertension); patients with pheochromocytoma; patients with metabolic diseases (for example, hyperthyroidism, diabetes mellitus).
Pregnancy:
It is not recommended to prescribe Grippostad Reno during pregnancy due to the lack of reliable clinical data confirming the safety of the drug during this period.
It has not been established whether xylometazoline is excreted in breast milk, therefore the use of the drug during lactation (breastfeeding) is not recommended.
Interaction with other drugs:
Sharing the drug Grippostad Reno with tricyclic MAO inhibitors may, due to the cardiovascular effects of these drugs, lead to an increase in blood pressure.
Overdose:
Symptoms of drug overdose Grippostad Reno or accidental ingestion: nausea, vomiting, cyanosis, fever, convulsions, tachycardia, arrhythmias, collapse, cardiac arrest, arterial hypertension, pulmonary edema, respiratory failure, mental disorders, depression of central nervous system function, drowsiness, decreased body temperature, bradycardia, coma.
Treatment: activated carbon, gastric lavage, oxygen; if necessary, phentolamine (5 mg intravenously with saline or 100 mg orally); carrying out symptomatic (including anticonvulsant) therapy.
Storage conditions:
Store in a dry place, protected from light, at a temperature not exceeding 25°C.
Release form:
Grippostad Reno spray for nasal use 0.1%: in bottles with a sprayer of 10 ml;
Grippostad Rhino drops nasal 0.1%:
in bottles with a pipette cap 10 ml.
Grippostad Rhino drops nasal for children 0.05%
: in bottles with a pipette cap 10 ml.
Compound:
Grippostad Reno spray for nasal use 0.1%: 1 ml of spray contains xylometazoline hydrochloride 1 mg, benzalkonium chloride (50% solution) 0.4 mg;
Grippostad Rino nasal drops 0.1%: 1 ml drops contains xylometazoline hydrochloride 1 mg, benzalkonium chloride (50% solution) 0.4 mg;
Grippostad Rino nasal drops for children 0.05%: 1 ml drops contains xylometazoline hydrochloride 0.5 mg, benzalkonium chloride (50% solution) 0.4 mg;
excipients: citric acid monohydrate - 0.5 mg, sodium citrate 2H2O - 2.6 mg, glycerin 85% - 24.0 mg, purified water - 976.5 mg.
Additionally:
Sympathomimetic decongestants may cause reactive hyperemia of the nasal mucosa, especially after prolonged use and overdose. These congestion may be accompanied by a narrowing of the airways and simulate the symptoms of a runny nose, which leads to repeated or even chronic use of Grippostad Reno by patients. This, in turn, can lead to chronic swelling of the nasal mucosa (drug-induced rhinitis), causing atrophy of the nasal mucosa.
Vasoconstrictor
Release forms
- 10 ml - dark glass bottles with a pipette cap (1) - cardboard packs. 10 ml - dark glass bottles with a pipette cap (1) - cardboard packs.
Description of the dosage form
- Nasal drops for children 0.05% transparent, colorless to slightly colored, free from visible foreign particles, odorless. Solution-drops nasal 0.1% transparent, colorless to slightly colored, free from visible foreign particles, odorless.
pharmachologic effect
Vasoconstrictor for local use in ENT practice. Alpha adrenergic agonist. When applied to the mucous membranes, it causes vasoconstriction, as a result of which local hyperemia and swelling are reduced. For rhinitis, it facilitates nasal breathing.Pharmacokinetics
When applied topically, it is practically not absorbed; plasma concentrations are so small that they cannot be determined by modern analytical methods.Special conditions
Should not be used for a long time, for example, for chronic rhinitis. For colds, in cases where crusts form in the nose, it is preferable to administer it in the form of a gel. Use in pediatrics Xylometazoline should be prescribed with caution to children under 2 years of age (gel - up to 7 years).Compound
- 1 ml xylometazoline hydrochloride 500 mcg Excipients: benzalkonium chloride 50%, citric acid monohydrate, sodium citrate dihydrate, glycerol 85%, purified water. xylometazoline hydrochloride 1 mg Excipients: benzalkonium chloride 50% (0.4 mg/1 ml), citric acid monohydrate, sodium citrate dihydrate, glycerol 85%, purified water.
Grippostad Rino indications for use
- Acute allergic rhinitis, sinusitis, hay fever, otitis media (to reduce swelling of the nasopharyngeal mucosa), preparing the patient for diagnostic procedures in the nasal passages.
Grippostad Rhino contraindications
- Angle-closure glaucoma, atrophic rhinitis, arterial hypertension, tachycardia, severe atherosclerosis, hyperthyroidism, surgical interventions on the meninges (history), hypersensitivity to xylometazoline.
Grippostad Rino dosage
- 0,05 % 0,1 %
Grippostad Rino side effects
- With frequent and/or prolonged use: irritation of the mucous membrane, burning, tingling, sneezing, dry nasal mucosa, hypersecretion. Rarely: swelling of the nasal mucosa (more often with long-term use), palpitations, heart rhythm disturbances, increased blood pressure, headache, vomiting, sleep disorders, visual disturbances. With long-term use in high doses: depression
Grippostad® C Capsules - 1 capsule. paracetamol - 200 mg ascorbic acid - 150 mg caffeine - 25 mg chlorpheniramine maleate - 2.5 mg excipients: lactose monohydrate; glyceryl tristearate; gelatin capsule shell composition: body - gelatin; water; titanium dioxide cap - gelatin; quinoline yellow; water; yellow dye “Sunset”; titanium dioxide in a blister 10 pcs.; in a cardboard pack 1 or 2 blisters. Grippostad® Rino Spray for nasal use - 1 ml xylometazoline hydrochloride - 1 mg benzalkonium chloride (50% solution) - 0.4 mg excipients: citric acid; sodium citrate; glycerin (85% solution); purified water - up to 1 ml in bottles with a 10 ml spray; 1 bottle in a cardboard pack. Nasal drops - 1 ml xylometazoline hydrochloride - 1 mg excipients: benzalkonium chloride (50% solution) - 0.4 mg; citric acid monohydrate - 0.5 mg; sodium citrate dihydrate - 2.6 mg; glycerol 85% (glycerol) - 24 mg; purified water - 975.5 mg in dark glass bottles of 10 ml; 1 bottle in a cardboard pack. Nasal drops for children - 1 ml xylometazoline hydrochloride - 0.5 mg excipients: benzalkonium chloride (50% solution); citric acid monohydrate; sodium citrate dihydrate; glycerin 85% (glycerol); purified water - up to 1 ml in dark glass bottles of 10 ml; 1 bottle in a cardboard pack. Grippostad® Powder for oral solution - 1 pack. paracetamol - 0.6 g excipients: coated ascorbic acid (ascorbic acid, ethylcellulose); anhydrous colloidal silicon dioxide; aspartame; anhydrous citric acid; sucrose; lemon flavoring in sachets of 5 g; in a cardboard pack 5 pcs.
Description of the dosage form
Grippostad® C Hard gelatin opaque capsules, size No. 1, yellow cap, white body. The contents of the capsules are white to yellowish powder. Grippostad® Rhino Spray, nasal drops and nasal drops for children: transparent, colorless to slightly colored solution, free of visible foreign particles, odorless. Grippostad® Homogeneous powder from white to yellowish color with a characteristic lemon odor.
pharmachologic effect
Grippostad® S Analgesic, antipyretic. Grippostad® Rhino Decongestant (alpha2-adrenomimetic). Grippostad® Analgesic, antipyretic.
Pharmacokinetics
Grippostad® Rhino When applied topically, it is practically not absorbed; plasma concentrations are so small that they cannot be determined by modern analytical methods.
Pharmacodynamics
Grippostad® C Combined drug to eliminate the symptoms of colds. Paracetamol has an analgesic (pain-relieving) and antipyretic effect (influence on the thermoregulation center in the hypothalamus). Ascorbic acid is involved in the regulation of redox processes, carbohydrate metabolism, blood clotting, tissue regeneration (restoration), and in the synthesis of steroid hormones; increases the body's resistance to infections, reduces vascular permeability, reduces the need for vitamins B1, B2, A, E, folic acid, pantothenic acid. Improves the tolerability of paracetamol and prolongs its action (slow elimination). Caffeine has an antispasmodic (relaxing) effect, dilates the bronchi, tones the blood vessels of the brain, stimulates the heart, and has a general tonic effect. Chlorpheniramine is an antihistamine that has an antiallergic effect: it reduces nasal discharge and congestion, lacrimation, and sneezing. The combination of drug components ensures better tolerance of symptoms of malaise and fever during influenza infections and other colds. Grippostad® Rino Xylometazoline is an imidazoline derivative and is an alpha2-adrenergic stimulant. Constricts the blood vessels of the nasal mucosa, resulting in reduced swelling and hyperemia (redness) of the mucous membrane. Facilitates nasal breathing during rhinitis (runny nose). The effect occurs within 5-10 minutes and lasts up to 10 hours. It does not disrupt the function of the ciliated epithelium of the respiratory tract mucosa. Reactive hyperemia practically does not occur after using the drug. Grippostad® Combined drug. Paracetamol has an analgesic (pain-relieving) and antipyretic effect. Ascorbic acid is involved in the regulation of redox processes, carbohydrate metabolism, blood clotting, tissue regeneration (restoration), and in the synthesis of steroid hormones; increases the body's resistance to infections, reduces vascular permeability, reduces the need for vitamins B1, B2, A, E, folic acid, pantothenic acid. Improves the tolerability of paracetamol and prolongs its action (slowing its elimination).
Indications for use of Grippostad rhino
Grippostad® C Grippostad® febrile syndrome in infectious and inflammatory diseases; pain syndrome of moderate or mild severity (headache, migraine, toothache, neuralgia, myalgia, arthralgia, algodismenorrhea (painful irregular menstruation). Grippostad® Rino acute allergic rhinitis (runny nose); acute respiratory infections with symptoms of rhinitis; sinusitis (inflammation of the mucous membrane of the paranasal sinuses); hay fever (allergic runny nose caused by pollen); otitis media (inflammation of the middle ear) - to reduce swelling of the mucous membrane of the nasopharynx; preparing the patient for diagnostic manipulations in the nasal passages.
Contraindications to the use of Grippostad rhino
Grippostad® C Grippostad® hypersensitivity to the components of the drug; gastrointestinal bleeding; portal hypertension (increased blood pressure in the portal vein); alcoholism; severe liver and/or renal failure; pregnancy (I and III trimesters); breastfeeding period; children's age (up to 15 years); deficiency of glucose-6-phosphate dehydrogenase; angle-closure glaucoma; prostatic hypertrophy with the formation of residual urine; severe arrhythmias; uncontrolled arterial hypertension. With caution: erosive and ulcerative lesions of the gastrointestinal tract (in the acute phase); liver and/or kidney failure; congenital hyperbilirubinemia (diseases in which the level of bilirubin in the blood is increased - Gilbert, Dubin-Johnson and Rotor syndromes). Grippostad® Rino hypersensitivity to the components of the drug; arterial hypertension; tachycardia; severe atherosclerosis; glaucoma; atrophic rhinitis; thyrotoxicosis; surgical interventions on the meninges (history); pregnancy; children under 6 years of age. With caution: diabetes mellitus; pheochromocytoma; IHD (angina pectoris); prostatic hyperplasia; thyrotoxicosis; breastfeeding period.
Grippostad rhino Use during pregnancy and children
Grippostad® C Grippostad® Contraindicated during pregnancy (in the first and third trimesters) and during lactation. Grippostad® Rhino Contraindicated during pregnancy. The use of Grippostad® Rhino during lactation is possible only as prescribed by a doctor in cases where the expected benefit to the mother outweighs the potential risk to the child, because There have been no studies confirming the safety of the drug for a child during breastfeeding.
Grippostad rhino Side effects
Grippostad® C In therapeutic doses, the drug is usually well tolerated. Sometimes allergic skin reactions are possible (skin rash, itching, urticaria, angioedema); gastrointestinal dysfunction (nausea, epigastric pain, dry mouth); difficulty urinating. Rarely - disorders of the blood system (anemia, leukopenia - low level of leukocytes in the blood, thrombocytopenia - low level of platelets in the blood). With long-term use in large doses (more than 12 capsules daily for more than 5 days) - hepatotoxic effect, blood system disorders; erosive and ulcerative lesions of the gastrointestinal tract; nephrotoxicity (papillary necrosis). Grippostad® Rhino With frequent (more than 4 times a day) and/or long-term use (more than 7 days) - irritation and/or dryness of the nasopharyngeal mucosa, burning, tingling, sneezing, hypersecretion. Grippostad® Allergic reactions (skin rash, itching, urticaria, angioedema), nausea, pain in the epigastric region; anemia, thrombocytopenia (low platelet count in the blood), agranulocytosis (complete or almost complete disappearance of granulocytes from the blood). With long-term use in large doses - hepatotoxic and nephrotoxic effects; hematopoietic disorder.
Drug interactions
Grippostad® C Grippostad® Stimulators of microsomal oxidation in the liver (phenytoin, ethanol, barbiturates, rifampicin, phenylbutazone, tricyclic antidepressants) increase the production of hydroxylated active metabolites, which determines the possibility of developing severe intoxications with small overdoses. Inhibitors of microsomal oxidation (cimetidine) reduce the risk of hepatotoxicity of the drug. Ethanol contributes to the development of acute pancreatitis. Reduces the effectiveness of uricosuric drugs. When the rate of gastric emptying decreases (propantheline), the effect of the drug slows down; when it accelerates (metoclopramide), it begins to act faster. Increases the toxicity of chloramphenicol. May enhance the effect of indirect anticoagulants Grippostad® Rino Incompatible with MAO inhibitors and tricyclic antidepressants.
Dosage of Grippostad rhino
Grippostad® C Orally, with a small amount of liquid, 2 caps. appointment. If necessary, repeat the same dose after 4-6 hours 3-4 times a day. The maximum daily dose should not exceed 12 caps. Grippostad® Rhino Intranasal. Nasal spray: adults and children over 6 years old - 1 spray from a spray bottle or 2-3 drops in each nasal passage, 3-4 times a day; should not be used more than 4 times a day. Nasal drops: adults and children over 6 years old - 2-3 drops of a 0.1% solution in each nasal passage 3-4 times a day, should not be used more than 4 times a day. Nasal drops for children: infants and children under 6 years of age - 1-2 drops of a 0.05% solution in each nasal passage 1 or 2 times a day; should not be used more than 3 times a day. Grippostad® Rhino (all dosage forms) should not be used for longer than 5-7 days, except as prescribed by a doctor. Repeated use of the drug is possible after a few days. The duration of therapy is determined by the doctor. Grippostad® Orally, contents 1 pack. You should pour it into a glass, add the required amount of hot water or tea, stir and immediately drink the resulting warm drink. If repeated use is necessary, the drug should be taken 3-4 times a day with intervals between doses of 4-8 hours. The highest daily dose for adults should not exceed 6 packs. For children, depending on age, the drug is given in the following doses (at the rate of no more than 10-15 mg (0.01-0.015 g) of paracetamol per 1 kg of body weight per dose): Table Dosage of Grippostad® for children
Overdose
Grippostad® C Grippostad® Symptoms: (caused by paracetamol): pale skin, loss of appetite, nausea, vomiting; hepatonecrosis (the severity of necrosis due to intoxication directly depends on the degree of overdose). Toxic effects in adults are possible after taking more than 10-15 g of paracetamol. Treatment: administration of SH-group donors and glutathione-methionine precursors - 8-9 hours after an overdose and N-acetylcysteine - after 12 hours. The need for additional therapeutic measures ( further administration of methionine, intravenous administration of N-acetylcysteine) is determined depending on the concentration of paracetamol in the blood, as well as on the time elapsed after its administration. Grippostad® Rino If the drug is used correctly, an overdose of the drug is impossible, because When applied topically, the drug is practically not absorbed. However, if the recommended dose is exceeded several times or if accidentally swallowed, an increase in side effects is observed.
GRIPPOSTAD ® RINO 0.05% NASAL DROPS
Xylometazoline hydrochloride
No. UA/3090/02/02 from 01/13/2016 to 01/13/2021
GRIPPOSTAD ® RINO 0.1% NASAL DROPS
Xylometazoline hydrochloride
Other ingredients: benzalkonium chloride, citric acid monohydrate, glycerol, sodium citrate, purified water.
No. UA/3090/02/01 from 01/13/2016 to 01/13/2021
GRIPPOSTAD ® RINO 0.1% NASAL SPRAY
Xylometazoline hydrochloride
Other ingredients: benzalkonium chloride, citric acid monohydrate, glycerol, sodium citrate, purified water.
No. UA/3090/01/01 from 12/18/2015 to 12/18/2020
Dnieper 79.56 UAH/pack.
..... 73.5 UAH/pack.
« PLANTAIN»
Dnepr, pl. Staromostovaya, 1, tel.: +380676575039
Zhytomyr 78.96 UAH/pack.
GRIPPOSTAD® RINO 0.1% NASAL SPRAY nasal spray, solution 0.1% fl. 10 ml No. 1, Stada ..... 73.99 UAH/pack.
« PHARMACY BAM»
Zhytomyr, st. Bolshaya Berdichevskaya, 95, tel.: +380981858362
Zaporozhye 80.99 UAH/pack.
GRIPPOSTAD® RINO 0.1% NASAL SPRAY nasal spray, solution 0.1% fl. 10 ml No. 1, Stada ..... 70.95 UAH/pack.
« WE WANT HEALTH»
Zaporozhye, st. Charivnaya, 68
Ivano-Frankivsk 81.64 UAH/pack.
GRIPPOSTAD® RINO 0.1% NASAL SPRAY nasal spray, solution 0.1% fl. 10 ml No. 1, Stada ..... 75 UAH/pack.
« MED-SERVICE»
Ivano-Frankivsk, st. Khotkevicha, 65, tel.: +380342722985
Kyiv 85.52 UAH/pack.
GRIPPOSTAD® RINO 0.1% NASAL SPRAY nasal spray, solution 0.1% fl. 10 ml No. 1, Stada ..... 71.5 UAH/pack.
« WE WANT HEALTH»
Kyiv, st. Heroiv Dnepra, 49
Kropyvnytskyi 79.17 UAH/pack.
GRIPPOSTAD® RINO 0.1% NASAL SPRAY nasal spray, solution 0.1% fl. 10 ml No. 1, Stada ..... 70.95 UAH/pack.
« WE WANT HEALTH»
Kropyvnytskyi, st. Popova Kosmonavta, 9, tel.: +380630346068
Lutsk 82.46 UAH/pack.
GRIPPOSTAD® RINO 0.1% NASAL SPRAY nasal spray, solution 0.1% fl. 10 ml No. 1, Stada ..... 73.6 UAH/pack.
« VOLYNFARM»
Lutsk, st. Lesi Ukrainki, 47, tel.: +380504361590
Lviv 82.26 UAH/pack.
GRIPPOSTAD® RINO 0.1% NASAL SPRAY nasal spray, solution 0.1% fl. 10 ml No. 1, Stada ..... 71.99 UAH/pack.
« PHARMACY BAM»
Lviv, st. Mazepa, 10, tel.: +380677538543
Nikolaev 81.3 UAH/pack.
GRIPPOSTAD® RINO 0.1% NASAL SPRAY nasal spray, solution 0.1% fl. 10 ml No. 1, Stada ..... 72.95 UAH/pack.
« WE WANT HEALTH»
Nikolaev, st. Nikolaevskaya, 15, tel.: +380512214072
Odessa 86.49 UAH/pack.
GRIPPOSTAD® RINO 0.1% NASAL SPRAY nasal spray, solution 0.1% fl. 10 ml No. 1, Stada ..... 72.02 UAH/pack.
« PHARMACY ENTER»
Odessa, cross. Sobornaya / Sadovaya, 2/20, tel.: +380487220404
Poltava 79.83 UAH/pack.
GRIPPOSTAD® RINO 0.1% NASAL SPRAY nasal spray, solution 0.1% fl. 10 ml No. 1, Stada ..... 72.99 UAH/pack.
« PLANTAIN»
Poltava, st. Diamond, 6/11, tel..
Xylometazoline hydrochloride – active substance of the drug. Additional components of the spray: benzalkonium chloride, sodium citrate, water, citric acid, glycerin.
Excipients contained in the drops: sodium citrate dihydrate, benzalkonium chloride, water, citric acid monohydrate, 85% glycerin.
Release form
Grippostad Rino is sold in the pharmacy chain in the form of a nasal spray and drops.
pharmachologic effect
Grippostad Reno represents decongestant means.
Pharmacodynamics and pharmacokinetics
The active component of the drug is xylometazoline hydrochloride – derivative imidazoline . This substance is alpha2-adrenergic stimulator . This drug constricts blood vessels nasal mucosa. This leads to a decrease in redness of the mucous membrane, making breathing easier when runny nose .
After using the medicine, its effect becomes noticeable after about 5-10 minutes and lasts for 10 hours. Reactive hyperemia after taking the drug in most cases it does not occur.
Indications for use
Grippostad Rino is used in case of edema nasal mucosa with cold . It is also an effective remedy for acute allergic , And runny nose with a lot of liquid mucus. The medicine can be used in preparation for diagnostic procedures V nasal passages .
Contraindications
Do not use the drug in case of hypersensitivity to its components (only as prescribed by a doctor), atrophic rhinitis , expressed arterial hypertension . In addition, drops and spray are contraindicated for children under 6 years of age, but they produce special drops for children that can be used at an earlier age.
Prescribe the drug with caution if pheochromocytomas , .
Side effects
If Grippostad Rino spray or drops are used frequently or for a long time, negative consequences such as irritation of the mucous membrane, tingling in the nose, dryness of the nasal mucosa, burning sensation in the nose, sneezing, hypersecretion .
In rare cases, adverse reactions such as heart rhythm disturbances, edema nasal mucosa, palpitations, marked increase, vomiting, visual disturbances.
With prolonged use of the drug in large doses, it may appear.
Instructions for use (Method and dosage)
The drug is used for nasal applications. Adults and children over 6 years of age should place one drop in each nostril as needed (but no more than three times a day). It is not advisable to take this remedy for longer than 5-7 days in a row. Before a new course of use, you need to take a break of several days.
It is advisable to consult a specialist about the advisability of continuing therapy.
At chronic rhinitis the use of the drug should be under medical supervision due to the risk of thinning the nasal mucosa.
When using a nasal spray, make one injection from a nebulizer 3-4 times every day. This remedy should not be used for more than 4 days in a row.
Nasal drops for children can be instilled into infants and children under 6 years of age in a dosage of 1-2 drops in each nostril. This should be done no more than 3 times a day.
Overdose
In case of overdose, as a rule, there is a worsening of adverse reactions. Therapy in this case symptomatic .
In addition, overdose or accidental oral use may cause mydriasis , .
Interaction
You cannot combine Grippostad Rino with tricyclic antidepressants And MAO inhibitors .
Terms of sale
Grippostad Rino is available without a prescription.
Storage conditions
The medicine should be stored at temperatures up to 25°C out of the reach of small children.
Best before date
The maximum shelf life of the drug is 5 years. After the bottle is opened, the medicine should be stored and used for no more than 6 months. Do not use drops or spray after the expiration date indicated on the package.
