home Auditorium 7 How to take cycloferon to treat diseases of bacterial and viral etiology. Cycloferon ointment: proper use, contraindications and reviews from doctors

How to take cycloferon to treat diseases of bacterial and viral etiology. Cycloferon ointment: proper use, contraindications and reviews from doctors

Cycloferon ointment is an effective local medicine that is used for infectious and inflammatory processes of viral, fungal and bacterial etiology on the skin. Dosage form for local application Cycloferon is a liniment. It has a wide range of applications, as it has a whole range of actions.

The active ingredients of Cycloferon stimulate the body's production of natural interferons, successfully fight inflammation and infectious agents: viruses, fungi and bacteria. Its use is indicated even for sexually transmitted infections. Prescribed for the treatment of chlamydia, fungal, bacterial, viral infections organs of the genitourinary apparatus, and acute manifestations infectious diseases. Cycloferon is also used in the treatment of chronic periodontitis.

Indications for use

Cycloferon is not prescribed to children; this liniment is used only in the practice of treating infections in adults. Indications for use are:

various manifestations of herpes of all types, including cytomegalovirus;
dermatitis, including atopic;
mycosis;
dermatosis;
eczema;
psoriasis.
vaginitis and vaginosis, provoked by nonspecific microflora;
urethritis and balanoposthitis of specific and nonspecific nature (chlamydial, gonococcal, fungal, trichomonas).

Compound

The active ingredient is meglumine acridone acetate. The liniment also contains N-methylglucamine and auxiliary components.

The therapeutic effect is provided by the following properties of meglumine acridone acetate:

increased activity of leukocytes in the affected area to relieve inflammation;
stimulation of interferon synthesis to increase the body's resistance to infectious agents.

Active substance has an immunomodulatory effect to accelerate recovery and prevent relapses of the disease.

Analogs

There are no drugs similar to cycloferon in composition. Cheap medicines, similar in therapeutic effect: Amiksin, Anaferon. The following analogues are also sometimes recommended: Viferon, Isoprinosine, Galavat, Oxolinic ointment.

Contraindications and side effects

This drug has virtually no contraindications:

It is not prescribed if you are allergic to the components of the ointment.
The instructions for use of Cycloferon do not recommend the use of the drug during pregnancy and breastfeeding.
The ointment is not recommended for use in pediatrics, that is, it is not prescribed to either a child or a teenager. As a rule, doctors prescribe Cycloferon to people over 18 years of age.

Cycloferon also has almost no side effects. Isolated mild allergic skin reactions have been reported. When using liniment, a slight burning sensation and hyperemia may occur. These effects last a short time and go away on their own, without treatment. Such side effects do not require visiting a doctor or refusing treatment with this drug.

If your doctor prescribes Cycloferon, you must inform him about all the medications you are taking for other reasons, as well as about the use of any unconventional methods treatment.

It is not advisable to use the drug in combination with other local means. If you intend to do this, you must consult your doctor. Cycloferon may enhance the effect of certain medications, so the attending physician should be aware of all medications and folk remedies treatment of a specific patient. This will allow him to determine the optimal regimen for using a complex of drugs and treatment methods.

Cycloferon ointment can be used by applying it to the skin, mucous membranes, or placing it inside the vagina or urinary canal.

General characteristics. Compound:

Active ingredient: substance - meglumine acridone acetate in terms of acridone acetic acid - 50.0 mg, obtained according to the following recipe: acridone acetic acid - 50.0 mg, N-methylglucamine (meglumine) - 38.5 mg;

excipients: benzalkonium chloride - 0.1 mg, 1,2-propylene glycol - up to 1.0 ml.

Description: transparent yellow liquid with a slight specific odor.

Pharmacological properties:

CYCLOFERON® is a low-molecular-weight interferon inducer, which determines a wide range of its biological activity (antiviral, immunomodulatory, anti-inflammatory). CYCLOFERON® is effective against the herpes virus and other pathogens. Has direct antiviral effect, suppressing virus reproduction by early stages(1-5 days) of the infectious process.

The main clinical effect of CYCLOFERON® liniment is associated with the induction of early α-interferon. The drug normalizes the cytokine imbalance of opposite forms of the immune response. The local pharmacotherapeutic effect of the drug CYCLOFERON® is due to the stimulation of the local immune response in lymphoid tissue mucous membrane. The effectiveness of CYCLOFERON® liniment in the treatment of chronic periodontitis is manifested in growth suppression pathogenic microorganisms and normalization of the level of secretory immunoglobulin A in the fluid of periodontal pockets, which ensures high-quality sanitation oral cavity, helping to reduce inflammation and bleeding of the gums.

Indications for use:

In adults in complex therapy:

Herpetic infection of the skin and mucous membranes;

Nonspecific vaginitis and vaginosis;

Chronic periodontitis.

Important! Get to know the treatment

Directions for use and dosage:

Locally: When herpetic infection Liniment is applied in a thin layer to the affected area 1-2 times a day for five days. For genital herpes - intravaginal instillations once a day, 5 ml for 10-15 days daily.

In the treatment of nonspecific vaginitis and bacterial vaginosis: the drug is administered intravaginally, 5-10 ml daily for 10-15 days, 1-2 times a day. It is possible to use tampons impregnated with liniment. At chronic forms diseases, the drug combines well with other medications (vaginal tablets, suppositories).

For intravaginal use: open the tube, pierce the membrane with a syringe (volume 5 ml) with a disposable needle, draw up liniment, remove and discard the needle. In a lying position, insert the filled syringe into the vagina and use the piston to squeeze out the liniment.

If the package contains a vaginal applicator, pierce the membrane of the tube and place the applicator on the hole. Squeeze the liniment into the applicator cavity until the entire piston is pushed out. Remove the filled applicator from the opening of the tube, insert it into the vagina and use a piston to squeeze out the liniment.

To prevent free evacuation of the drug, the vaginal entrance is sealed with a small sterile cotton swab for 2-3 hours. If necessary, you can repeat the course after 14 days.

When treating chronic periodontitis, before using liniment, it is advisable to rinse the periodontal pockets with an antiseptic, then apply the drug in a volume of 1.5 ml with a cotton swab to the gums using the application method (do not rub in) 1-2 times a day with an interval of 10-12 hours. Duration of therapy is 12-14 days. If necessary, repeat the course after 14 days.

Features of application:

The drug has a bitter taste. It is not recommended to intensively rub the drug into the gums. Do not allow the drug to come into contact with the mucous membrane of the eyes. In case of contact, rinse eyes with water. Does not affect driving ability vehicles. If there is no therapeutic effect, you should consult a doctor.

Side effects:

Allergic reactions. A short-term burning sensation and slight local hyperemia are possible. Side effects are mild and do not require discontinuation of the drug.

Interaction with other drugs:

Liniment CYCLOFERON® is compatible with all medicines, traditionally used in the treatment specified diseases(chemotherapeutic drugs, etc.). For chronic forms of diseases, the drug combines well with other medications (vaginal tablets and suppositories). Enhances the effect of antibiotics, antiseptics and antifungal drugs.

Contraindications:

Pregnancy, period breastfeeding, age under 18 years, hypersensitivity to the components of the drug. Use during pregnancy and breastfeeding The use of the drug during pregnancy and breastfeeding is contraindicated.

Overdose:

There is no information about an overdose of the drug.

Storage conditions:

In a place protected from light at a temperature of 15-25 ° C. Keep out of the reach of children. Shelf life: 2 years. The drug should not be used after the expiration date indicated on the packaging.

Vacation conditions:

Over the counter

Package:

Liniment 5% 5 ml in insulin bottles, 5 bottles in a single-sided blister pack, 1 blister pack along with instructions for use in a cardboard pack. 5 ml or 30 ml in an aluminum tube. Tube along with instructions for use in a cardboard box. A pack with a 30 ml tube contains 5 vaginal applicators, or is packaged without applicators.

You cannot do without local therapy for herpes. The manufacturers of the now popular drug Cycloferon also know this. That's why they released it in the form of liniment (liquid ointment), which is very convenient for intravaginal administration and application to the gums. The effectiveness of the drug has been clinically proven.

Compound

Cycloferon ointment (liniment) 5% contains active substance– meglumine acridone acetate. It is this that is responsible for healing effect drug. The liniment contains benzalkonium chloride and 1,2-propylene glycol as auxiliary substances. They set the shape and consistency of the medicine, promote its rapid release, etc.

Operating principle

Cycloferon liniment 5% is a “smart” medicine that directly acts on the virus, and at the same time helps our body produce more interferons, increasing its resistance.

How is everything going?

A virus (including herpes) enters a cell of the human body and infects it.
Our infected cell begins to produce offspring, which are already infected.
Cycloferon penetrates into it, changes its functioning, which leads to the fact that it produces offspring that are no longer capable of infecting other cells, which are subsequently excreted naturally.

At the same time, the Cycloferon molecule acts on our macrophages (cells immune system), provoking an increase in the production of interferons that can protect us by preventing viruses from entering the cells of the human body and their reproduction.

Liniment also has the ability to stimulate a local (local) response of the immune system of the mucous membrane.

As for the treatment of periodontitis, Cycloferon in the form of liniment suppresses the growth of pathogens and normalizes the level of secretory immunoglobulin A in periodontal pockets. This contributes to high-quality sanitation of the mouth and reduction inflammatory reactions, bleeding gums.

Indications for use

5% liniment can and should be used for:

skin and mucous membranes;
nonspecific vaginitis and vaginosis;
chronic periodontitis.

Cycloferon in the form of liquid ointment is indicated for use exclusively in adults. It is not prescribed by pediatricians.

How to use?

Liniment refers to external dosage forms. For herpes, Cycloferon ointment is applied in a thin layer to the affected area up to 2 times. day for 5 days. In the case of genital herpes, intravaginal instillations are done once a day and use up to 5 ml of the drug each time. Course – 10-15 days.

Nonspecific vaginitis and bacterial vaginosis are treated with the drug as follows: liniment is injected into the vagina in an amount of 5-10 ml every day 1-2 r. within 10-15 days. For convenience, you can soak a tampon made of cotton wool and a bandage with the medicine. At chronic diseases It is rational to combine with suppositories and vaginal tablets of other pharmaceuticals.

Many women are probably interested in the question: how, exactly, to introduce the drug into the vagina? First you need to open the packaging (primary and secondary), pierce the membrane of the tube with a 5 ml syringe using a needle, draw out the medicine, then remove the needle and throw it away. So that the liniment gets into Right place, you need to lie down, guide the filled syringe with the drug into the vagina and squeeze it there with a piston.

There is another way. Its use is possible if there is a special applicator in the package. In this case, it is worth squeezing the medicine into its cavity (the entire piston must be pushed out). Next, you need to remove the filled applicator from the tube, insert it into the vagina and squeeze out the liniment with a piston.

Cycloferon ointment may leak when used intravaginally, so it is rational to prevent this by tamponing (for 2-3 hours). Tampons can be made from cotton wool.

The course of therapy with 5% Cycloferon liniment can be repeated no earlier than after 2 weeks.

Chronic periodontitis is treated with this drug in 12-14 days. What is needed for this? First, you need to rinse the periodontal canals with an antiseptic (chlorhexidine, for example), and then apply the medicine in an amount of 1.5 ml to the gums using a cotton swab. This must be done before 2 p.m. per day every 10-12 hours. The course of treatment can be repeated after 2 weeks if necessary. Attention! Do not rub Cycloferon ointment into the gums!

Contraindications

It is worth understanding that anyone, even the most safe drug, there are contraindications. Cycloferon liniment 5% is not recommended for use by children, pregnant women, nursing mothers and people with a history of allergies to any of its components.

The drug is popular among doctors and patients. It is not addictive and therefore suitable for frequent use. However, as a rule, for herpes it is prescribed in combination with other pharmaceuticals, and not as monotherapy.

Release form

Liniment 5% in the form clear liquid yellow color, with a weak specific odor.

Compound

Liniment contains: acridoneacetic acid (in the form of N-methylglucamine salt) 50 mg per 1 g.
Excipients: benzalkonium chloride, 1,2-propylene glycol.

Package

tube 5 ml.

pharmachologic effect

Cycloferon is an immunomodulator. Meglumine acridone acetate has wide range pharmacological activity: antiviral, immunocorrective, anti-inflammatory. The main clinical effect is associated with the induction of early alpha-interferon production mainly by epithelial cells and lymphoid elements of the mucous membrane. Activates T-lymphocytes and natural killer cells, normalizes the balance between subpopulations of T-helpers and T-suppressors. The drug increases the biosynthesis of functionally complete antibodies (high-avidity), which makes therapy more effective. Normalizes indicators cellular immunity. Anti-inflammatory activity is ensured by enhancing the functional activity of neutrophils and activating phagocytosis.
Cycloferon is effective against herpes virus, cytomegalovirus, human immunodeficiency virus, human papillomavirus (prevents reproduction by suppressing the multiplication of viral particles). The effectiveness of the use of Cycloferon as a component of immunotherapy in the complex treatment of acute and chronic bacterial infections(chlamydia, bacterial and fungal infections genitourinary area). Effective in the treatment of chronic periodontitis due to the suppression of pathogenic microorganisms, enhancing the synthesis of sIgA in the fluid of periodontal pockets to normal levels. Provides high-quality sanitation, improves the hygienic condition of the oral cavity, reduces hyperemia and bleeding of the gums, reduces tooth mobility, and eliminates unpleasant odor.

Indications

As part of complex therapy in adults:
- Herpetic infection of the skin and mucous membranes.
- Treatment of urethritis and balanoposthitis of nonspecific and specific (gonorrhea, candidiasis, chlamydia and trichomonas) etiology.
- Treatment of nonspecific bacterial vaginitis and vaginosis.
- Treatment of chronic periodontitis.

Contraindications

Children's and adolescence up to 18 years old ( clinical researches have not been carried out in children).
- Pregnancy.
- Lactation period (breastfeeding).
- Increased sensitivity to the components of the drug.

Use during pregnancy and breastfeeding

The drug is contraindicated for use during pregnancy and lactation (breastfeeding).

Directions for use and doses

For herpes infection Liniment is applied in a thin layer to the affected area 1-2 times a day for 5 days. For genital herpes - intraurethral (intravaginal) instillations 1 time/day, 5 ml for 10-15 days daily. It is possible to combine liniment with other antiherpetic agents (both systemic and local).
When treating nonspecific and candidal urethritis intraurethral instillations are performed in a volume of 5-10 ml, depending on the level of damage to the urethra. In case of defeat upper section urethra in men, the cannula of a syringe with liniment is inserted into the external opening of the urethra, then the opening is clamped for 1.5-3 minutes, after which the instillation solution is evacuated by gravity. After 30 minutes, the patient is advised to urinate. Longer exposure may lead to swelling of the urethral mucosa. The course of treatment is 10-14 days. For lesions posterior section urethra, area of the seminal glands, use intraurethral instillations through a catheter in a volume of 5-10 ml of the drug for 10-14 days every other day (5-7 instillations per course).
In the treatment of urethritis of specific etiology- combined use of intraurethral instillations of Cycloferon with specific antimicrobial drugs according to traditional regimens.
For balanoposthitis the glans penis should be treated and foreskin Cycloferon liniment 1 time/day (1/2 bottle or tube of 5 ml) for 10-14 days.
In the treatment of candidal vaginitis, nonspecific vaginitis (endocervicitis) and bacterial vaginosis The drug can be used both as monotherapy and as part of complex treatment. Use intravaginal instillations of the drug, 5-10 ml, for 10-15 days, 1-2 times a day. In parallel, in the case of combined damage to the vaginal and urethral mucosa, it is advisable to use intravaginal and intraurethral instillations in volume (5 ml daily for 10-14 days). It is possible to use tampons impregnated with liniment. For chronic forms of diseases, the drug combines well with the use of official medicines (vaginal tablets, candles). To use intravaginally, you should open the tube, pierce the membrane with a disposable needle and syringe (volume 5 ml), draw up liniment, remove and discard the needle. Insert the filled syringe into the vagina in a lying position and use a piston to squeeze out the liniment. If the package contains a vaginal applicator: pierce the membrane of the tube, screw the applicator until it stops on the opening of the tube. Squeeze the liniment into the applicator cavity until the entire piston is pushed out. Remove the filled applicator from the opening of the tube, insert it into the vagina and use a piston to squeeze out the liniment. To prevent free evacuation of the drug, the vaginal entrance is sealed with a small sterile cotton swab for 2-3 hours.
In the treatment of chronic periodontitis Before using liniment, it is advisable to rinse the periodontal pockets with an antiseptic, then apply the liniment with a cotton swab in a volume of 1.5 ml (1/3 tube) to the gums using the application method (do not rub) 1-2 times a day with an interval of 10-12 hours. Duration of therapy 12 -14 days.
For all indications, if necessary, you can repeat the course of treatment with Cycloferon after 14 days.

Side effects

When prescribing the drug, the patient should be warned that liniment has a bitter taste. The patient should know that the drug should not come into contact with the mucous membrane of the eyes (in case of contact, rinse the eyes with water). It is not recommended to rub the drug into the gums.

special instructions

Cycloferon is compatible with all drugs used in the treatment of these diseases (including interferons, chemotherapy drugs). When used together, Cycloferon enhances the effect of antibiotics, antiseptics and antifungal drugs.

Storage conditions

The drug should be stored out of the reach of children, in a dry place, protected from light at a temperature of 15° to 25° C.

Best before date

During treatment it provides triple action: stimulates the human immune system, destroys the reproduction mechanism of viruses and effectively counteracts the inflammatory process. by the human body alpha, beta and gamma interferons are produced, which neutralize attacking harmful viruses and eliminate bacterial infection of the respiratory tract.

The drug helps cope with the infection by increasing the production of its own interferons.

Cycloferon ointment is prescribed initially in the following cases:

ineffectiveness of the treatment due to addiction;
manifestation allergic reaction for other drugs;
together with active medicine(Acyclovir), enhancing its effect.

Release form, composition and packaging

Cycloferon ointment is a yellow thick liquid that contains in 1 ml:

50 mg acridoneacetic acid;
excipients (propylene glycol, meglumine and benzalkonium chloride).

The drug is available in the form of 5% liniment in a metal tube with a capacity of 30 ml or 5 ml.

pharmachologic effect

The product is applied externally to skin or mucous surfaces of the mouth, genitals. Greatest effect appears on the first day of disease manifestation. It is recommended to lubricate the affected surface 3-4 times a day.

If the first day is missed, the treatment period is delayed. The drug effectively copes with recently penetrated viruses and bacteria, preventing their reproduction. But those microorganisms that entered the body before treatment began continue their harmful activities.

Mechanism of action

When lubricating the affected area of the skin or mucous membrane, the body's local protective response to the invasion of viruses is stimulated. In the oral cavity, with the development of pathogenic microorganisms, Cycloferon ointment disrupts the bacterial reproduction cycle. In this case, the own immune defense, secretory is secreted, protecting mucosal cells from the development of infection.

Meglumine acridone acetate (the active substance of the medicinal cream) helps the human body to recover faster:

Activation of leukocytes helps reduce inflammatory process in the body and at the site of application of the ointment.
Improving the quality of antiviral protection helps the body produce antibodies that destroy pathogens.
Increasing immunity ensures a person’s rapid recovery and prevents re-infection.

The active substance of the ointment destroys the infection at the cellular level, “stimulating” the defense forces to fight pests.

Indications

herpes infection affecting the skin;
manifestation on the mucous membranes of the mouth, lips, genitals;
chronic periodontitis;
bacterial diseases of the vagina;
viral lesions of the genitourinary area in women and men.

Contraindications

The drug Cycloferon in the form of ointment - toxic substance Therefore, external use of the medicine by women during pregnancy and breastfeeding is strictly prohibited. In pediatrics, ointment is not used at all.

Treatment with ointment is prohibited for inoperable forms of liver cirrhosis, so as not to hasten the death of the patient.

Also, you should not use the product if you are personally allergic. If the patient has an illness thyroid gland, the drug is allowed to be taken only after consultation with the treating endocrinologist.

Instructions for use

Instructions for use of the drug in the form of an ointment:

If it is necessary to repeat treatment with the drug, it is recommended to pause for 14-21 days.

Adverse reactions

Sometimes it appears by-effect after lubricating areas of the body with Cycloferon ointment: the skin turns red, itches, and burns. If the allergy is not severe, the drug is not discontinued and treatment continues.

Drug interactions

Treatment with Cycloferon liniment can be combined with any antimicrobial, antiseptic, and chemotherapeutic drugs.

It should be borne in mind that the drug enhances the effect of the drug when integrated use Therefore, the dosage is set only by the attending physician.

special instructions

Before using the product externally, you should do an allergy test:

apply liniment in a thin layer on inner surface elbow with an area of 1-2 square meters. cm;
do not remove the ointment for 12 hours.

If redness, burning or swelling does not appear, then the medicine can be used.