Gynepristone - emergency contraception or medical abortion? Ginepristone - instructions, consequences, analogues, action, side effects

If a woman decides to terminate the pregnancy, but excludes surgical intervention, if the pregnancy is no more than 6 weeks, the gynecologist can advise medical abortion. With this type of abortion, large doses mifepristone.

Gynepristone contains only 10 mg of mifepristone and is used as an “emergency contraception” after unprotected sexual intercourse.

How does Gynepriston work?

Gynepristone blocks the production of progesterone, which is necessary for normal pregnancy.

When progesterone is blocked, the inner layer of the uterus detaches. Detachment of the endometrium leads to softening and expansion of its neck. With an enlarged cervix and increased contractile activity, bleeding begins. Ginepristone, after taking a precisely calculated dose, leads to fetal rejection. The effectiveness of Ginepristone increases in combination with prostaglandin.

Gynepristone is a synthetic steroidal antigestagenic agent. Its effect depends on the stage of ovulation - it either inhibits it or changes the properties of the endometrium, preventing the implantation of a fertilized egg.

Side effects of Gynepristone

• Bleeding and cramping pain. This is normal reaction to terminate pregnancy;
• nausea, any other symptoms of dyspepsia;
• weakness, asthenia, headache;
• hives;
• hyperthermia;
• inflammatory and infectious processes in the pelvic organs;
• at ectopic pregnancy this drug may cause the fallopian tube to rupture. This may lead to fatal outcome;
• abdominal pain, pulling or aching, back pain.

The difference between Ginepristone and Postinor is the dosage regimen. One tablet is taken within 72 hours after sexual intercourse. The timing of taking Gynepristone does not affect its effectiveness. The drug is better absorbed if you drink it on an empty stomach and refrain from eating for another 2 hours after taking the tablet. Mifepristone in small doses usually does not cause adverse reactions.

Contraindications to the use of Ginepristone

• Pregnancy and lactation period. If taking Ginepristone is mandatory, stop breastfeeding for 2 weeks;
• adrenal insufficiency, renal failure And long-term use glucocorticosteroids;
• pathologies of the pelvic organs;
• increased sensitivity history of exposure to mifepristone drugs;
• bleeding disorders;
• bronchial asthma and other lung diseases;
• hypertension, arrhythmias, heart failure.

Gynepristone cannot be used as a method of permanent contraception. A simultaneous administration NSAIDs (ibuprofen, diclofenac, naproxen, etc.), acetylsalicylic acid and mifepristone drugs - excluded.

Ginepristone should not be used in children under 18 years of age. A teenager who takes an emergency contraceptive may disrupt his menstrual cycle. And it will be difficult to restore it. Due to the unformed hormonal background of a teenager, the drug may simply not work or cause bleeding.

After taking Gynepristone, you should visit a gynecologist. He must confirm that pregnancy has not occurred. Or, according to at least, conduct several pregnancy tests.

If unprotected sexual intercourse occurs, the condom breaks. The woman is firmly convinced that if pregnancy occurs, she will not maintain it - she should take a post-coital contraceptive. Unlike abortion pills, Ginepriston simply prevents pregnancy from occurring. From a psychological and physical health women are the best option.

Answers on questions

Emergency contraception can be safe too

Gynepristone - synthetic non-hormonal drug. His active substance, mifepristone, is an antagonist of progesterone (pregnancy hormone). By acting at the receptor level, gynepristone can prevent unplanned pregnancy. For this purpose, the drug is taken once, in a dosage of 10 mg. When using gynepristone within the first 48 hours after sexual intercourse, its effectiveness reaches 99 percent.

In what cases is gynepristone useful?

Sex is great. Doing it is pleasant and useful. But, whatever one may say, its main biological mission is reproduction. Therefore, every intercourse can ultimately lead to pregnancy.
The most obvious way to “get away with it” is to use contraception. Condoms will also save you from venereal diseases. But it happens that the latex assistant slips or breaks at the most important moment.

Nowadays, interrupted coitus is often chosen as contraception. And you don’t have to spend money on condoms, and the sensations are more natural. But the probability of getting pregnant is quite high. And it requires careful and competent actions from a man.

Some women prefer protective patches and pills. In this case, it is important not to forget to use the product before sexual intercourse. Not turning off the light in the dressing room or leaving your wallet in a taxi compared to this is childish (all very literally) babble.

And, of course, we must not forget what kind of world we live in. Victims of sexual violence should receive informational support in addition to psychological support. So that the memory of the nightmare does not last a lifetime.

How does gynepristone work?

Gynepristone affects progesterone at the receptor level. Its efficiency is 99 percent and does not depend on the phase menstrual cycle. If ovulation has not begun, it interferes with the process of egg maturation. If it does occur, it prevents the fertilized egg from attaching to the wall of the uterus. Thus, pregnancy does not occur. For the drug to be effective, it must be taken 72 hours after sexual intercourse.

Side effects and harm of gynepristone

The World Health Organization (WHO) has named mifepristone one of the most important medicines. The fact is that his discovery significantly increased the effectiveness of emergency contraception and made it practically safe.

Only in 14% of cases after taking gynepristone does pain appear in the lower abdomen, in 19% does uterine bleeding, nausea and dizziness are extremely rare. Nurses in Spanish schools even give mifepristone-based drugs to high school girls.

At the same time, it is important to remember that gynepristone is not ascorbic acid, and it should be taken only in the most extreme cases. In general, use condoms, because gynepristone will not save you from sexually transmitted diseases.

In addition, it is not recommended to take more than 10 mg of the drug (there is a possibility of overdose), and also for pregnant women and women who are breastfeeding, patients with adrenal insufficiency, porphyria and severe bronchial asthma. Due to the fact that mifepristone exhibits antagonism with glucocorticosteroids, they cannot be taken in combination.

Why is gynepristone better than other emergency contraceptives?

Doctors have been concerned about the problem of emergency contraception for a long time. The first significant achievements occurred in the 70s of the last century. But all the drugs that existed before the discovery of mifepristone are significantly inferior to it in terms of safety and effectiveness. For example, intrauterine device absolutely not recommended nulliparous women, A hormonal pills cause hormonal disbalance in the body, seriously disrupt the menstrual cycle and cause obesity.

Use less progressive and more dangerous means these days is as illogical as walking down the street in knight's armor and using a Motorola phone.

Gynepristone is not an abortion, but not a contraception either.

Many people confuse emergency contraception with medical abortion. And this is fundamentally wrong. Medical abortion is the termination of pregnancy during the first six weeks. Gynepristone and other means of emergency contraception cannot terminate pregnancy, since they are used in the first 72 hours after sexual intercourse, when it has not yet occurred. Unlike medical abortion, taking gynepristone does not require the presence of a doctor. Again, we remember Spain and school nurses distributing pills to high school girls.

On the other hand, gynepristone is not an ordinary contraception. Use it as a condom, patch or birth control pill it is forbidden. Firstly, minimal, but still harm to the body will be caused. Secondly, with multiple doses, the effectiveness of the drug may decrease. So try to think about the problem before you run out of other options.

Confucius said that the strength of the state lies in the family. He's damn right about that. Sex with a regular partner whom you can completely trust will protect you from many possible troubles and improve your health.

Gynepristone is a popular emergency contraceptive with a high effectiveness of 97%. The drug in combination with others medications also used for medical purposes . Women are often interested in how to take gynepristone correctly and whether it is possible to perform a medical abortion with this drug at home.

CONSULTATION ON THE RESULTS OF ANALYSIS AND ULTRASOUND - 500 rubles. (at the request of the patient) Medical abortion - from 3500 (all inclusive!)

How does gynepristone work?

The active ingredient of the drug is mifepristone, a synthetic steroid that inhibits the production of progesterone.

Progesterone is a hormone that is actively produced during ovulation, creating conditions for the implantation of a fertilized egg into the uterine cavity. Thanks to special hormonal levels, the uterus does not contract when a zygote enters there, and it quietly implants (attaches) to the walls of the organ, and then develops, forming an embryo.

Ginepristone creates unfavorable conditions for conception by slowing down ovulation. The result of suppressing progesterone production is that the endometrium (the inner layer of the uterus) remains underdeveloped, so the egg cannot implant.

If you are already pregnant, this synthetic progestogen enhances the effect of prostaglandins that stimulate labor. Prostaglandins are used during childbirth, but a similar effect has also been seen on early stages pregnancy - in other words, when taking gynepristone, it begins .

Mifepristone contained in the drug stimulates the sensitivity of receptors to prostaglandins and blocks the perception of progesterone. As a result, changes occur in the endometrial layer. The smooth muscles of the uterus begin to contract rhythmically under the influence of prostaglandins, pushing the fertilized egg out of the cavity.

How does Gynepriston differ from analogues and why is it not suitable for medical abortion?

Ginepristone - analogue and other drugs based on this active substance (Agesta, Zhenale, Ginestril, Escapelle). But it contains a small dose of the active substance - 0.01 g. Therefore, it is used as a means of emergency contraception when sexual intercourse has occurred, but conception (fusion of germ cells) has not yet occurred.

They contain a dose ten times higher than the content of mifepristone in gynepristone. If you take genipristone at home during pregnancy, in the form in which it is sold in pharmacies, there is a 99% chance that your pregnancy will continue. There are cases when, after taking the drug, menstruation begins, but the fetus still remains in the uterus. As a result, a woman discovers pregnancy when the fetus has already begun to move. It is no longer possible to talk about abortion at this stage, so childbirth is coming. But it’s difficult to imagine how such experiments will affect a child.

At the same time, gynepristone can be chosen as emergency contraception. All drugs - analogues of gynepristone - act on the body according to the same principle, having the active substance mifepristone. But despite big choice contraceptives, Ginepriston is very popular and is characterized positive reviews gynecologists. This is due to the fact that the medicine does not affect ovulation and spares the ovaries.

This drug is also prescribed by gynecologists for the treatment of tumors and cysts. Naturally, the choice of medicine should be made only after passing and passing . This is due to the fact that the medicine is effective only up to a certain size of tumors; beyond this limit, on the contrary, it can provoke their growth.

How to take Gynepristone

Gynepristone is considered a very effective post-coital contraceptive that prevents pregnancy as a result of unprotected intercourse. For many years, the drug Postinor was very popular. He has proven himself really well, he has high efficiency, but it provokes hormonal disruption, suppressing the release of the oocyte from the follicle. If Postinor is used incorrectly, a woman could develop an ovarian cyst or other problems. There will be no such problems with Ginepristone, and its effectiveness is very high.

The drug can be taken both before and after sexual contact. The highest concentration of mifepristone is achieved 24 hours after taking the tablet. Then every 12 hours the effectiveness decreases by 20-25%.

By taking Gynepristone within 24 hours after unprotected intercourse, you can be 97% sure that conception will not occur. After 3 days the drug becomes ineffective. You can take the medicine on any day of the cycle.

If gynepristone was taken and pregnancy still occurred, you will have to have an abortion (medical, , ), because there is a high risk of having a child with pathologies.

As a rule, after taking the medication, menstruation occurs on time or a few days earlier. Delay is rare.

What nuances should you pay attention to when taking Gynepristone: contraindications

Gynepristone - highly effective remedy emergency contraception, but there are a number of caveats:

• The manufacturer writes that taking this medication is incompatible with smoking by women over 35 years of age. In fact, smoking reduces the effectiveness of mifepristone, regardless of the girl's age. Having smoked several cigarettes, a woman at both 20 and 38 years old increases the chances of an unwanted pregnancy;
• It is important not to take Gynepristone on a full stomach. The drug provokes muscle contractions, including gastric ones, causing vomiting. After it, the action is reduced to nothing.
• You should not use emergency contraception more than 1-2 times a year. If a woman took 200 mg of drugs containing mifepristone over 2 months and did not become pregnant, then the next time 10 mg of gynepristone will not have any effect at all. In this case, it is better to use more by strong means such as Postinor or Escapella. But they have significant drawbacks: Escapelle is effective only in the first phase of the cycle, and Postinor causes hormonal imbalance and amenorrhea. Ginepristone is good as the first means of emergency contraception, gentle on the body.
• The drug should not be taken together with analgesics (No-shpa, Analgin, Paracetamol). In this case, problems with the heart and blood vessels, a strong increase in pressure and the opening of uterine bleeding are possible.
• Ginepristone is contraindicated in women with arrhythmia, heart failure and arterial hypertension.
  

What side effects does Gynepriston have?

Despite the fact that Ginepristone is a relatively safe means of emergency contraception for a woman’s body, it, like all medications, has side effects. In particular:

• PMS symptoms are more pronounced. Deterioration of mood, increase blood pressure, headache, nagging pain lower abdomen - a natural side effect of antiprogesterones. The advantage of Gynepristone is that these symptoms do not last long because menstruation occurs on time or a few days earlier.
• The drug enhances the effect of drugs aimed at blood clotting. If a woman is undergoing treatment and taking coagulants, she should stop using Gynepristone.
• The drug reduces the effect of glucocorticosteroids (Hydrocortisone, Dexamethasone, Prednisolone), so it should not be taken by people with adrenal and renal insufficiency.
  

In general, Gynepristone is well characterized by both patients and gynecologists. It does not have such a stressful effect on the body as Postinor, which has a significant proportion of hormones. But still, you should first consult with a gynecologist, who will select the reliable means emergency contraception in accordance with the patient’s health characteristics.

Where to find emergency contraception or medical abortion in St. Petersburg

At the Diana Clinic in St. Petersburg you can take all tests and undergo specialized female ultrasound on a new device and get advice from an experienced gynecologist with the highest category. The doctor will prescribe a drug that will leave minimal consequences after stopping unwanted pregnancy.

Ginepristone is a steroidal and antigestogenic medicine that is used to terminate pregnancy in the early stages, but not more than forty-two days of amenorrhea.
Three weeks of pregnancy is the period when, after using this drug, its effectiveness reaches almost one hundred percent.

But if it is amenorrhea, which is more than forty-nine days, after the first day last menstrual period, then the effectiveness of the drug will deteriorate significantly.
And like any medical abortion, it should only be carried out in a clinic, under the supervision of a gynecologist. But there are times when after medication interruption pregnancy, the fetus does not die, and an incomplete abortion occurs. In such cases, the doctor informs the patient that the pregnancy still needs to be terminated, since the child in this case may be born with defects, sometimes even incompatible with life.

Instructions for use

The package of the drug "Ginepristone" usually contains one or two tablets. These pills prevent progesterone receptors from activating and disrupt its regulation regarding the attachment of a fertilized egg. More, this drug interferes with the normal course of ovulation, which in the absence of progesterone slows down greatly. Also, mucus begins to thicken in the cervix, which creates an unfavorable environment for the continuation of pregnancy.

Procedure for abortion with gynepristone

This technology involves a three-time visit to the doctor.

1. An hour before visiting the gynecologist, you need to have a light breakfast, but nothing heavy. And already directly at the doctor’s office, the pregnant woman drinks three tablets of gynepristone. The dose of each of them is two hundred milligrams. After the procedure for taking the pills, the patient remains within the clinic for several more hours so that the doctor can monitor the woman’s tolerance to the drug. In many women, on the same day you can detect bloody issues, but only five percent have a final abortion.
2. Two days later, the woman comes to the doctor again. Under the doctor's supervision, she takes two more misoprostol tablets. Each of them is equal to 200 mcg. After this drug, the woman remains under observation for three or more hours. While the woman is in the clinic, she should already start bleeding, but if this is not observed, the gynecologist gives the woman two more tablets to drink. The duration of bleeding largely depends on how far into pregnancy the woman is. If we are talking about a period of four weeks of pregnancy, then often the abortion proceeds as follows: normal menstruation. But the discharge can last from one to two weeks. But if we're talking about later pregnancy, then bleeding may be heavy.
3. And the third visit to the doctor must be made two weeks after the woman took Misoprostol. This technique is needed in order to exclude the possibility of continuing the pregnancy, or detecting an incomplete abortion. This examination is extremely important throughout the course of abortion, so you should not neglect it, as this may be fraught with consequences.

Side effects of Gynepristone

• Gag reflexes, cramps in the lower abdomen, diarrhea, lethargy, fatigue, migraines, dizziness.
• Increased body temperature, severe and prolonged bleeding, chills

Therefore, if you definitely decide to end your pregnancy, do not expose your body to severe, possible consequences, and immediately contact a doctor, under whose strict guidance you will quickly recover.

Ginepristone, the instructions for which will be described in detail in the article, is emergency contraceptive, intended to terminate an unwanted pregnancy if sexual intercourse was unprotected or protected by unreliable means of contraception. The product belongs to the group of gestagens. Before using the drug, it is important to read the instructions, the contents of the tablets, possible side effects and reviews from women who have tried the drug on themselves.

Release form and composition of the drug

Ginepristone is sold in pharmacies in the form of flat-cylindrical tablets, colored light yellow with a greenish tint. There are three types of packaging in which the drug can be found: blister packaging, polymer jar or cardboard box. Any of the offered packages contains up to two tablets of the product.

Active substance , contained in one tablet, allows you to terminate pregnancy at the initial stages. The following substances are indicated as auxiliary components in the instructions:

• microcrystalline cellulose;
• sodium carboxymethyl starch;
• calcium stearate.

pharmachologic effect

The drug is intended for cases where it is urgently necessary to prevent pregnancy. Chemical structure molecules of mifepristone allows us to talk about Gynepristone as a synthetic steroid drug. In the human body naturally steroid hormones produced by the adrenal glands.

Mifepristone, penetrating into a woman’s body, instantly blocks the receptors of progesterone, a hormone that helps female body create all conditions for the successful formation and course of pregnancy. Having lost progesterone, the uterus is unable to provide the favorable environment necessary for the egg to fertilize, the mucus on the cervix thickens, and some changes occur associated with its functional layer. As a result of the processes occurring, the egg is unable to attach to the walls of the uterus.

In addition, the instructions for use state that the drug slows down ovulation. Ovulation is a process when an egg is released from a mature ovarian follicle, which subsequently enters the fallopian tube, where it is fertilized. At normal operation reproductive system Ovulation occurs regularly every 19-45 days, depending on the menstrual cycle and the characteristics of the woman’s body.

Indications for use

Taking the drug is indicated if there is a risk of unwanted pregnancy after unprotected sexual intercourse or unreliable means of contraception. Thanks to your pharmacological properties medicine allows you to stop the process fertilization of the egg. Reviews strongly recommend taking the product within three days after sexual intercourse, as long as it is possible to prevent fertilization of the egg. Most favorable time In order to take a pill, it will be two hours before a meal or two hours after it.

Gynepristone: contraindications

The drug has a large list of contraindications, so you should read the instructions and reviews before starting medication use. The list of contraindications includes factors such as:

If the drug is taken by a woman during lactation, breast milk can be given to a child only after two weeks after taking a contraceptive. It is prohibited to use the medication during pregnancy.

Gynepristone: side effects

Gynepristone, side effects which appear infrequently, has an effect on the body, sometimes leading to to the following unfavorable factors:

However, often taking the drug turns out to be painless and does not cause discomfort to the woman, which is confirmed by numerous reviews about the medication. Before using a contraceptive to terminate a pregnancy, you should consult a qualified gynecologist and find out possible risks manifestations of side effects.

Directions for use and overdose

The drug should be taken no later than three days after sexual intercourse. It is advisable to take a tablet two hours before starting a meal or two hours after it. The medication has no or minimal effect on the menstruation process, so you can take the pills at any time, regardless of your cycle. The product should not be used as a primary contraceptive for continuous protection of sexual intercourse.

A dose of the drug up to two grams is considered safe for human body. As a result of an overdose, there is a risk of adrenal insufficiency. In this case, it is necessary to begin appropriate treatment.

Gynepristone: analogues

The drug has a large number of analogues containing the same active substance , the action of which is also aimed at emergency protection against unwanted pregnancy. Among the most popular and effective analogues drugs can be distinguished:

• mifepristone;
• mytholian;
• Mifeprex;
• agesta;
• and others.

Reviews about the drug

Gynepristone, reviews of which are mostly positive, has been tried by thousands of women and is recommended to their friends. as an effective emergency contraceptive.

During sexual intercourse, my partner’s condom broke, and since pregnancy is now extremely undesirable for me, I had to buy a contraceptive that would quickly eliminate all risks. The pharmacy recommended this drug. The instructions indicate to take within three days after sexual intercourse. I was afraid of adverse effects on the body, but everything worked out. The remedy worked negative consequences didn't leave.

A favorite remedy for unwanted pregnancy when sexual intercourse occurs without contraception or it turns out to be unreliable. It acts gently, does not disrupt the cycle, periods come on time, and there are no troubles in the form of pain in the lower abdomen or headaches.

I purchased the drug when I encountered damage to the condom during sexual intercourse with my partner, after reading reviews about the drug. What frightened me most were the comments about the negative effects on the body, but since the number of purely positive opinions exceeded half, I decided to try it. I was worried that my condition would worsen after taking the pill, but nothing happened, everything was fine. By the way, I took the product in the first days of menstruation, and it had no effect on the discharge.

Gynepristone – effective contraceptive, helping a woman in emergency cases when sexual intercourse was unreliably protected or not protected at all. The drug causes abortion at the earliest early stages. The instructions describe in detail all aspects of taking the drug, and reviews confirm the effectiveness of the medication.