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Antidepressants for men. How much do they drink? Medicines for children

05.05.2016 20:10

Antidepressants without a doctor's prescription

An antidepressant is a drug that affects the production of serotonin and norepinephrine and affects/regulates a person’s mood. In most cases, they are medicines, but we will look at those that:

  • widely available;
  • do not require a doctor's prescription;
  • natural, unnatural, safe and not so much.

Let us immediately note that we will not touch on powerful pharmaceuticals, because... they have a huge number of side effects, and taking them will turn out to be “treating one thing, crippling another.”

What is responsible for the presence or absence of depression?

Serotonin is a substance that is responsible for a person’s mood. It is located in the brain, gastrointestinal tract, and hemocytes. However, modern stress leads to a decrease in its level, and accordingly, it is necessary to increase it in every possible way.

Lack of serotonin leads to the following disorders: bad dream, Bad mood, appetite disturbances (constant need for sweets and simple carbohydrates), depression, headaches, muscle and other pain.

Signs of serotonin deficiency: depression, obesity, bulimia, insomnia, narcolepsy, sleep apnea, headaches, migraines, fibromyalgia, premenstrual syndrome.

What antidepressants can be bought without a prescription?

Maprotiline (Lyudiomil)

This is a tetracyclic antidepressant that helps relieve apathy, anxiety and improve mood. Possible weak effect when taken.

Side effects include seizures, especially in case of overdose.

Prozac (prodel, fluoxetine, fluval, profluzac)

Selective serotonin inhibitor. Received wide application at doctors. Helps relieve panic, anxiety, intrusive thoughts, premenstrual disorders.

Of the side effects - wide list from headaches and blood pressure problems to sexual dysfunction. Withdrawal syndrome is possible.

Bioavailability - up to 70%. The composition is unnatural.

Zyban (Bupropion, Nosmoke, Wellbutrin)

Action: selective inhibition of reuptake of norepinephrine and dopamine. Helps with the abolition of various addictions: nicotine, narcotic. Removes lethargy, fatigue, hypersomnia.

Side effects: hypertension, convulsions, nausea, insomnia, tinnitus.

Bioavailability - up to 20%. The composition is unnatural.

Paxil (paroxetine, adepress, plisil, rexetine, sirestill, plisil)

Action: selective serotonin reuptake inhibitor. Helps get rid of depression, anxiety, phobias, panic attacks, nightmares.

Side effects - a wide list that affects following systems body: central nervous system, autonomic, cardiovascular, lymphatic, endocrine, genitourinary, respiratory, gastrointestinal tract. Overdose can lead to coma.

Bioavailability - 100%. The composition is unnatural.

Deprim

Renders sedative effect. Helps get rid of depression, improve sleep, improve mood, increase physical and mental activity.

Side effects - allergies, nausea, vomiting, constipation, lethargy, fatigue, drowsiness.

Persen

Has a sedative effect. Helps reduce nervous tension, depression, improve mood.

Side effects - allergies, constipation.

Bioavailability - not studied. The composition is semi-natural.

Novo-passit

Has a sedative effect. Helps improve mood, reduce anxiety, reduce nervous tension, depression.

Side effects - allergies, nausea, heaviness in the stomach, heartburn, diarrhea, constipation, weakness, joint pain, drowsiness, depression, dizziness.

Bioavailability - not studied. The composition is semi-natural.

The most effective and safe antidepressant

5 hydroxytryptophan (5 HTP) is a natural amino acid that is converted into serotonin in the body. This occurs when the amino acid decarboxylase is exposed to aromatic L-amino acids.

To get 5 hydroxytryptophan, the body must obtain tryptophan, which is quite energy-consuming and some people have problems with its synthesis. And by taking 5 HTP, you eliminate one link in the metabolism and actually give the body a preparation from which it can easily make serotonin.

Helps relieve depression, remove headaches, improve sleep, improve mood, reduce anxiety, and normalize appetite.

Side effects - allergies, nausea, diarrhea.

Bioavailability - not studied. The composition is natural.

Herbal antidepressants

It is quite possible to buy other natural antidepressants that are sold at the pharmacy. Usually these are various herbal infusions or herbal mixtures that need to be brewed and drunk. There are no possible side effects positive effect, allergies, nausea, diarrhea.

Tinctures - maralia root, rhodiola rosea, immortalinum, lemongrass, leuzea, ginseng, meadow clover, blue honeysuckle, oregano, motherwort. They improve mood, resistance to stress, increase performance, stimulate psychomotor functions, reduce or eliminate depression.

Please note that tinctures in most cases are alcohol-based, which has a negative effect on the body.

Herbs and their combinations - honey, oregano, chamomile, dill, caraway, valerian, peppermint, hops, hawthorn, angelica, calendula. Helps with seasonal depression, insomnia, improves sleep, performance, reduces fatigue, tension, and depression.

Precautionary measures

Unfortunately, in our country it is customary to immediately run to the pharmacy for any health problem, without visiting a doctor. Of course, this can be attributed to the fact that the doctor may be incompetent or indifferent to his patients.

In addition, statistics show that the majority of people who buy antidepressants on their own do not suffer from depression or mental problems. They just need a good rest.

However, there are qualified specialists who can help without the use of pharmaceuticals or medicinal plants. Therefore, we recommend that you first consult a doctor or psychiatrist, and only after that go to the pharmacy.

In this way, possible side effects pharmaceutical drug. Since some of them form addiction and dependence.


Today, depression affects not only adults, but also children and adolescents. Many specialist studies and a huge number of articles and books have been devoted to this disease and methods of combating it. If translated from “scientific” into ordinary language, depression is a loss of strength and desire to live. Symptoms of this disease are apathy and constant anxiety and fatigue, lethargy and gloom.

Modern pharmacology offers the latest generation of antidepressants to combat this disease. How many generations of thymoleptics (also called drugs that work against depression) exist today, what do they have in common and how do they differ from each other, what is their mechanism of action? These and other questions will be discussed in the article presented to your attention.

What are antidepressants?

Thanks to which you can relieve symptoms and even prevent depressive conditions. The main mechanism of their action is aimed at adjusting the biochemical activity of the human brain. its components constantly interact with each other through special substances- neurotransmitters. According to one theory, depressive disorders occur when the brain, due to various reasons, the level of any mediator or biogenic amine decreases significantly: dopamine, norepinephrine or serotonin. Antidepressants of the latest generation, like all previous ones, have a regulating and corrective effect on the biochemical processes of the brain by changing the concentration of one or another biogenic amine.

What are they needed for?

In addition to the fact that modern antidepressants help cope with the symptoms of depression, they are often used to get rid of the following problems:

  • various pains of unknown origin;
  • appetite or sleep disturbances;
  • severe fatigue or loss of strength;
  • nervousness or feelings of constant tension;
  • attacks of nervousness or anxiety;
  • problems concentrating or remembering.

Generations of antidepressants

Before considering how many generations of drugs against depression have been created to date, we need to remember that antidepressants were discovered only in the middle of the 20th century. Today, depending on the time of invention and the beginning of use in clinical practice, as well as from the action of antidepressants, it is customary to distinguish four generations of these drugs.

First generation drugs

The first generation, discovered in the 50s of the last century, is represented by cyclic tricyclic thymoleptics (TCAs). These include the following medicines: “Amitriptyline” (antidepressant, the very first one discovered) and its derivatives, as well as the drugs “Nefazodone”, “Anafranil” and “Melipramine”. These compounds block the reuptake of norepinephrine, thereby increasing its concentration. However, TCAs blocked not only norepinephrine (norepinephrine), but also all other neurotransmitters that came in their way, which led to a large number of unpleasant side effects, primarily such as sharp increase blood pressure and increased heart rate. Drugs in this group are quite toxic, and the likelihood of an overdose when using them is very high, which is why they are so little used in the treatment of depressive disorders today.

In addition, the first generation includes drugs that are no longer used today and contain irreversible monoamine oxidase inhibitors (MAOIs) - Iproniazid, Tranylcypromine, Isocarboxazid. Their action is based on the suppression of activity nerve endings neurons of the brain, resulting in increased concentrations of serotonin and norepinephrine.

Second generation drugs

The second generation, unlike the first, has a more selective, but also weaker effect on neurotransmitters and the neurons themselves. It includes tetracyclic irreversible (MAO-B) and reversible (MAO-A) monoamine reuptake inhibitors, represented by drugs such as Lerivon, Ludiomil, Pyrazidol and a number of others. Due to the fact that many quite serious side effects occurred when taking them, as well as due to interaction with different drugs and unpredictability of effects, drugs in this group are used extremely rarely. It is quite difficult to find antidepressants from the group of monoamine reuptake inhibitors in pharmacies. But in some cases they are found under other trade names. So, experts say that the drug “Lyudiomil” is the same tablets “Maprotiline”, the price, manufacturer and country are just different.

Third generation

Modern researchers have found that about 30 mediators are involved in the functioning of the brain and nervous system, but only three of them are “involved” in depression: serotonin, dopamine and norepinephrine (norepinephrine). The third generation includes selective serotonin reuptake inhibitors (SSRIs), represented by the most commonly used modern antidepressants, like the drugs Zoloft, Citalopram, Prozac, Cipralex, Paroxetine, Plizil and many others. These medications do not block all mediators, but only one - serotonin. In terms of their potency, they are inferior to first-generation drugs, but they have significantly fewer side effects than any other predecessors. All SSRI drugs are very effective and should be tolerated approximately equally by patients. However, each of us has our own body individual characteristics, and it is because of them that the number and strength of side effects will vary in each specific case. Doctors say the most common unpleasant consequences Third generation medications include insomnia, dizziness, nausea and anxiety.

SSRI drugs are quite expensive. Thus, for the fairly well-known and widely used drug “Citalopram”, the price in pharmacies, depending on the brand under which it is released, can vary from 870 to 2000 rubles.

Fourth generation antidepressants

These usually include drugs from the SSRI group (selective serotonin and norepinephrine reuptake inhibitors). These are the latest generation antidepressants, such as Cymbalta, Milnacipran, Remeron, Effexor, which block the uptake of both norepinephrine and serotonin. The drugs Zyban and Wellbutrin do not interact with serotonin, but retain dopamine and norepinephrine. The development of drugs belonging to this group began only in the mid-90s of the last century, and every year more and more new drugs appear.

Doctors cannot say unequivocally that this particular group contains the best antidepressant; this is basically impossible, since for the treatment of various types of depressive disorders, medications are selected individually, taking into account the health characteristics of each patient.

Popular modern thymoleptics

Knowing about the serious impact of drugs in this group on nervous system, it is necessary to remember that all possible - both positive and negative - consequences can only be predicted and leveled qualified specialist- doctor. Taking into account all the individual characteristics and having made a diagnosis, it is the doctor who will be able to prescribe exactly those antidepressants that can best help in your particular case, with minimal side effects. If any problems arise while taking the prescribed medication, it is the attending physician who will be able to adjust or change the treatment regimen. Today, most practitioners recommend that patients with depressive disorders drugs from the group selective inhibitors reuptake of serotonin and norepinephrine, effective impact which have been tested in practice. Medicines such as Milnacipran, Fluxen (Fluoxetine), Duloxetine, Velaxin (Venlafaxine) are the most typical and widely used antidepressants of the latest generation. Let's consider the most popular thymoleptics in the treatment of depressive disorders.

Medicine "Flucosetine"

This drug is one of the first representatives of the SSRI group; it combines both antidepressant and stimulant effects. The medicine "Fluxen", also known as the antidepressant "Fluoxetine", helps reduce anxiety and tension, eliminates feelings of fear and improves mood. Its most effective use, according to practicing psychotherapists, is in cases of asthenic depressive disorders with apathy, as well as depression varying degrees severity and obsessive states. This medicine is also used in the treatment of bulimia. The antidepressant Fluoxetine was first registered in 1974 in the USA, and in last decade it came out on top in sales in the UK, only under a different name trade name- Prozac. In Russia, this medicine is widely used, and many practicing doctors confirm that they prescribe it or its generics to patients for various depressive conditions.

The drug "Paroxetine"

This is the most powerful representative of the group of selective inhibitors of selective serotonin uptake, widely used in the treatment of anxiety and depression. Today there are quite a lot of medications whose active ingredient is paroxetine. This and Russian drug"Adepress" from "Veropharm", the medicine "Plizil" from the Croatian company Pliva, the Hungarian tablets "Rexetine" from and many others. Regardless of the name of the drug "Paroxetine", reviews of it from both patients and doctors are mostly positive.

The drug "Wellbutrin"

Better known as "Zyban" or "NoSmoke". The active ingredient in all three drugs is bupropion hydrochloride, which increases the amount of dopamine and norepinephrine in the brain. Medicines containing this active ingredient not only relieve symptoms of depression, but also help overcome the emotional consequences of quitting nicotine. This medication improves mood and increases performance. Reviews from those who got rid of nicotine addiction with the help of drugs such as Wellbutrin, KnowSmoke and Zyban, they talk about high efficiency these drugs during the period of smoking cessation.

Medicine "Cymbalta"

A drug of the fourth generation of antidepressants, which is an inhibitor of the reuptake of norepinephrine and serotonin, simultaneously carrying out a slight uptake of dopamine. This drug, the active ingredient of which is duloxetine, has a rather high speed of action compared to other antidepressants. According to reviews from both doctors and patients, a clear antidepressant effect appears by the end of the first - beginning of the second week of use. In addition, this drug is characterized by uniform action throughout the entire time of its use. However, there is a group of patients, according to whose reviews the effect of this medicine, if it occurs, is very weak. As already mentioned, individual characteristics of the course of biochemical reactions quite often lead to the fact that one or another medication prescribed by a doctor may not have the expected result.

What is the price?

Today it is quite difficult to talk about prices for medications. This is due to the fact that the foreign exchange market is extremely unstable, and new antidepressants for the most part come to us from foreign manufacturers, whose prices are presented in euros. That is why the table below presents the minimum and maximum prices in rubles, since it is simply impossible to average them. Some of the drugs that were received earlier are still sold at the old prices, while new ones are much more expensive.

Group

Active substance

Tradename

in rubles

Tricyclic antidepressants

amitriptyline

"Elavel"

imipramine

"Imizin"

clomipramine

"Anafranil"

maprotiline

"Lyudiomil"

Selective serotonin reuptake inhibitors (SSRIs)

sertraline

Zoloft

paroxetine

"Paxil"

fluvoxamine

"Fevarin"

fluoxetine

"Prozac"

citalopram

"Cipramil"

escitalopram

"Lenuxin"

Serotonin and norepinephrine reuptake inhibitors (SSRIs)

bupropion

"Wellbutrin"

venlafaxine

"Velaxin"

duloxetine

"Cymbalta"

If you carefully look at the table, you will notice that it does not contain second-generation drugs, namely MAOIs (monoamine reuptake inhibitors). It's not a mistake. The thing is that these antidepressants, which have big amount unpleasant side effects and incompatibility with many drugs, are practically not used in European countries. In the USA, the medications “Isocarboxazid”, “Ugenelzin” and “Tranylcypromine” are used quite rarely, and in our country the drug “Nialamide” is used. All of the above medications are available only under the supervision of psychiatrists.

This table clearly shows that the price for “classical” tricyclic antidepressants is significantly lower than for newer drugs from the SSRI and SSRI groups. Thus, it is not possible to talk about the high availability of effective antidepressant drugs for the majority of the population. However, your doctor can help you choose a less expensive drug with similar properties, the so-called generic.

Interaction with other drugs

Antidepressants can interact with other medications, even those that seem absolutely safe and familiar to us. The most active in this regard are tricyclic thymoanaleptics and monoamine oxidase inhibitors, but drugs from the SSRI and SSRI groups practically do not interact with other medications. In any case, if your doctor prescribes you any medications against depression, be sure to find out whether you can combine them with the use of other medications, dietary supplements, and even teas and herbal decoctions.

Strange as it may sound, many people who need to take thymoleptics due to various reasons, they ask how often you can combine the use of “hot” drinks and pills for depression. The answer to this question is quite simple: do you want to risk your mental and physical health, and maybe even life, try it! The fact is that both alcohol and antidepressants have a serious effect on the central nervous system and the brain, and such double pressure can negatively affect both the “flight control center” itself, that is, the brain, and the organs and systems subordinate to it. Whether or not it is worth combining is a decision that you and only you can make.

Instead of a conclusion

You shouldn’t think and rack your brains about which antidepressants are better and more effective. If you feel that each new day is becoming more difficult to live than the previous one, that you don’t have enough strength even for the simplest and most mundane things, contact a specialist! The doctor will be able to diagnose your disease and prescribe necessary treatment by choosing the medications that are most suitable for you. These may not only be antidepressants. The arsenal of today's medicine is quite extensive: different kinds psychotherapy, physical exercise and acupuncture, breathing practices and physiotherapeutic procedures.

Antidepressants are used in the treatment of depression, a list of which can be seen below. Antidepressants are drugs that selectively affect a person’s depressive state. These drugs and antipsychotics for depression can be used to relieve affective-delusional syndromes in children and adults.

  • Moclobemide;
  • Bethol;
  • Toloxatone;
  • Pyrazidol;
  • Imipramine;
  • Amitriptyline;
  • Anafranil;
  • Pertofran;
  • Trimipramine;
  • Azafen;
  • Maprotiline;
  • Mianserin;
  • Fluoxetine;
  • Fevarin;
  • Citalopram;
  • Sertraline;
  • Paroxetine;
  • Cymbalta.

These are only some of the antidepressants used to combat nervous disorders and depression. All of them are divided into several classifications.

Calming

Anti-depressants are a classification of the most common drugs used to combat depression.

Amitriptyline belongs to the classic type of mild antidepressants with a tricyclic structure. It is distinguished from Imipramine by its rather strong sedative effect. It is used for anxious and agitated types who are able to manifest themselves with “vitality”. This drug Available in the form of tablets and injections.

Another domestic antidepressant is Azafen, or Hypophysin. It is used to combat the symptoms of “minor” depressive disorders of the cyclothymic register. The drug has moderate sedative and thymoanaleptic effects.

Mianserin, or Lerivon, is a drug that has a strong sedative effect when used in small doses. Due to this effect, it can be used to treat cyclothymia in combination with insomnia. It is able to cure depression with major episodes.

Stimulating

Moclobemide, or Aurorix, is a selective MAO inhibitor. The drug has a powerful stimulating effect on people suffering from inhibited types of depression. It is prescribed for somatized types of depression. But the drug is strictly prohibited for use in anxiety depression.

Imipramine, or Melipramine, is the first fully studied tricyclic antidepressant. It is used in cases of high prevalence of melancholy and lethargy, and with suicidal thoughts. The drug is available in both tablet and intramuscular injections.

Fluoxetine is a drug that has a thymoanaleptic effect. Its second name is Prozac. The drug is effective during the treatment of depression with obsessive-phobic symptoms.

This type of medication is called a selective serotonin reuptake inhibitor (SSRI). The drug is devoid of some effects of clinical tricyclic antidepressants:

  • antihistamine;
  • adrenolytic;
  • cholinolytic.

Pertofran is a more powerful version of Imipramine (desmethylated). It has a brighter activating effect. Used in combination with depersonalization.

Balanced drugs

The second name of Pyrazidol is Pirlindol. The drug is produced in Russia. It is a reversible inhibitor of MAO type A, like Moclobemide. This drug is used to prevent and treat depression of the inhibited type, as well as depressive disorders with pronounced alarming manifestations. The advantages of the drug are that it can be taken for glaucoma, prostatitis and heart pathologies.

Another powerful drug created as a result of the synthesis and introduction of a chlorine atom into the imipramine molecule is Anafranil. It is used to treat resistant depression and to relieve the affective phases of severe depression.

Maprotiline, or Ludiomil, is an antidepressant with a tetracyclic structure. It has a fairly powerful thymoanaleptic effect when interacting with anxiolytic and sedative components. It can be used for circular depression in combination with ideas of self-blame. The drug is used for involutional melancholia. Maprotiline is produced in the form oral medications and injections.

Reversible monoamine oxidase inhibitors and selective reuptake inhibitors

Bethol refers to domestic drugs, which are prescribed for depressive disorders of asthenic and anergic types. It is used to treat the depressive phase of cyclothymia.

Fevarin and Fluoxetine belong to the classification of drugs with thymoanaleptic action. The drugs have a vegetative stabilizing effect.

Citalopram and Tsipramil are other names for thymoanaleptic antidepressants that can be used to treat depression. They belong to the group of sedating serotonin reuptake inhibitors (SSRIs).

Afobazole is an over-the-counter antidepressant. It is used to combat somatic diseases with adaptation disorders, anxiety states, neurasthenia and oncological and dermatological diseases.

The drug has a good effect in treating sleep disorders and relieving PMS symptoms. But it is worth considering that it is contraindicated for children and women during pregnancy and lactation.

Tricyclic

Trimipramine, or Gerfonal, is used in the treatment of depression with increased anxiety. This is one of the most powerful drugs of this kind. Its psychotropic activity is similar to Amitriptyline. When carrying out treatment, it is worth considering the list of contraindications of this antidepressant:

  • dry mouth;
  • orthostatic hypotension;
  • problems with urination.

New generation antidepressants

Sertraline and Zoloft are names of antidepressants with a strong thymoanaleptic effect with a weak stimulating effect. Moreover, the drugs do not have anticholinergic or cardiotoxic properties.

They achieve maximum effect when fighting somatized people with some manifestations of bulimia.

Paroxetine is a derivative of piperidine. It has a rather complex bicyclic structure. The main properties of Paroxetine are thymoanaleptic and anxiolytic. They appear when there is stimulation.

The drug shows itself well in the fight against endogenous and neurotic depression, their melancholy or inhibited variants.

Venlafaxine is an antidepressant used for depression due to severe mental disorders such as schizophrenia, etc.

Opipramol is used to treat somatized and alcoholic depression. It is able to prevent vomiting, convulsions and generally stabilize the autonomic nervous system.

Toloxatone, or Humoril, is similar in its effect on the human body to Moclobemide. The drug does not have anticholinergic or cardiotoxic properties. But it copes well with treating depression with pronounced inhibition.

Cymbalta or Duloxetine are used to combat depression with panic attacks.

Side effects

Most antidepressants have a fair number of side effects. Their list is quite long:

  • hypotension;
  • arrhythmia;
  • sinus tachycardia;
  • violation of intracardiac conduction;
  • suppression of bone marrow functions;
  • agranulocytosis;
  • thrombocytopenia;
  • hemolytic anemia;
  • dry mucous membranes;
  • violation of accommodation;
  • intestinal hypotension;
  • problems with urination;
  • increased appetite;
  • increase in body weight.

Such as a result of taking tricyclic antidepressants side effects occur quite often. In contrast, antidepressants that are serotonin reuptake inhibitors have less pronounced side effects. But it could be:

  • frequent headaches;
  • insomnia;
  • anxiety states;
  • depotentiating effects.

If combination therapy is used for treatment, that is, drugs of both types are used simultaneously, then serotonin syndrome may occur, characterized by an increase in temperature, signs of intoxication of the body, and disturbances in the functioning of the heart and blood vessels.

Any antidepressants for depression should be taken only after a complete medical examination and an accurate and complete diagnosis.

And for children they are prescribed with extreme caution. Be sure to do this under the supervision of a doctor so as not to harm the body.

Medicines can help you escape from depression: mild antidepressants without prescriptions, which are sold in pharmacies. Psycho-emotional exhaustion affects performance, general condition life, mood, attitude towards others. Chemical processes that occur in the brain imbalance health internal organs, launching new chains of pathological metabolic processes.

Causes of depression

A depressed, depressed state can be caused by various factors, although it manifests itself with similar symptoms:

  • Situational depression develops in response to the inability to solve any life problem, stress, severe shock, dissonance between desires and results;
  • Somatized depression is manifested by additional pathological processes in the work of internal organs;
  • Hormonal depression is the body's response to sharp fluctuations hormones during pregnancy, after childbirth, with internal endocrine disorders.

Depression is expressed by a decrease in the level of endorphins and enkephalins, reluctance to change anything, apathy, indifference to what is happening, increased irritability, fatigue.

Serious disorders are treated by specialists, medications are taken strictly as prescribed by the doctor.

You can get out of a depressed state and motivate yourself to overcome the difficulties that have arisen with the help of over-the-counter medications.

Depression pills without prescription


Are antidepressants sold without a doctor's prescription? Self-medication is not encouraged in any area of ​​medicine, but if you choose antidepressants yourself, you should give preference to the new generation of drugs.

  1. Quickly affects the body;
  2. No or minimal side effects;
  3. Combines well with other medications;
  4. Not addictive when taken for a long time

Depending on the effect the drugs have on the body, they are divided into three groups:

  • Calming
  • Stimulating
  • Complex

Sedatives sedatives relieve irritability, anxiety, and save from insomnia and headaches.


Stimulating drugs are required for people who fall into apathy, melancholy, melancholy, who are unable to cope with the lack of motivation for active life, work and rest.

Depending on the active substance, which forms the basis of the drug, are distinguished:

  • Tricyclics
  • Selective serotonin reuptake inhibitors
  • Serotonin reuptake activators
  • Selective serotonin, norepinephrine uptake inhibitors
  • Heterocyclic drugs
  • Monoamine oxidase inhibitors
  • Complex antidepressants

Group of tricyclic antidepressants


Amitriptyline– tablets and solution for intramuscular injections that have a sedative effect. It is used for manic-depressive psychoses, bulimia nervosa, and enuresis. Reduces diuresis, relieves pain. The list of side effects includes fatigue, drowsiness, hallucinations, nervous excitability, disorientation, tachycardia, nausea, speed dial weight.

Doxepin indicated for depression, neurosis and neurosis-like conditions, anxiety against their background, psychosis, alcohol addiction, organic lesions brain It is used to treat panic states, sleep disturbances in the background neurotic reactions. Has an analgesic and antipruritic effect.

Imipramine has been used for a long time and is considered one of the first drugs for treating depression. It has a stimulating effect, improves mood, increases body tone, relieves melancholy, lethargy, and lethargy. Appointed as part of complex therapy for the treatment of migraine, consequences of head injury, drug addiction, panic attacks.

Despite the fact that the drug for depression is prescribed in small doses even in childhood, it has a large list of side effects, contraindications, and is not compatible with all medications. Treatment should be discontinued by gradually reducing the dosage. Its analogue is desipramine.

Nortriptyline– a medicine for endogenous depression, used as part of complex therapy with other drugs.

Side effects include dry mucous membranes, urinary retention, and heart rate, tachycardia, nervous excitement, loss of orientation, hallucinations.

Group of selective serotonin reuptake inhibitors


Drugs in this group are used for disorders accompanied by obsessive states, fears, phobias, and panic attacks.

Incorrect dosage is manifested by tremors of the limbs, even convulsions, tachycardia, dizziness, vomiting, and a sharp rise in blood pressure.

This group includes:

  • sertraline,
  • paroxetine,
  • fluoxetine,
  • fluvoxamine,
  • citalopram and their analogues.

It has become quite a popular tool Prozac:

  • Heals obsessive states;
  • Relieves feelings of anxiety and uncertainty;
  • Relieves symptoms of PMS;

Like many antidepressants, it is contraindicated during pregnancy and breastfeeding.
Medicines from the group of selective serotonin and norepinephrine uptake inhibitors act similarly.

Group of heterocyclic drugs


Medicines in this group treat, along with depressive disorders, sleep and appetite disorders, and are recommended for older people.

This group includes:

  • Mianserin
  • Nefazodone
  • Remeron
  • Trittico

Group of monoamine oxidase inhibitors

Medicines effective for panic attacks, somatic depression, fear open spaces.

This group includes:

  • phenelzine,
  • befol,
  • moclobemide and their analogues.

As a result of taking it, anxiety decreases and improves social adaptation, the desire to live is restored. The most popular and in demand in modern medical practice are new generation drugs.

Antidepressants without prescriptions of herbal origin


Herbal preparations widely used in complex therapy for the treatment of depression. Most of them have a sedative effect due to natural ingredients:

  1. Deprim is a drug based on St. John's wort. It has an antidepressant effect, stabilizes sleep, and increases activity. Indicated for depression, anxiety, weather dependence, and during menopause. Analogues of Deprim are such drugs as Neuroplant, Doppelhertz Nervotonic, Negrustin, Gelarium;
  2. Complex drugs, which include mint, lemon balm, valerian - novo-passit, persen and other medicines, the names of which are often heard in television advertisements. They cannot be called full-fledged antidepressants, but they will help with insomnia, stress, increased anxiety, fatigue, irritability;
  3. Preparations based on hawthorn, motherwort, and peony calm the nervous system;
  4. Preparations based on Leuzea increase performance, relieve fatigue and lethargy;
  5. Good antidepressants are medicines based on ginseng. However, it is recommended to use them in the cold season, since skin cells become very sensitive to sun rays, the risk of skin pigmentation increases.

How to diagnose depression?


The diagnosis of depression and everything connected with it has been heard more and more often lately.

In some ways, depressive states have become “fashionable”: an accelerated pace of life modern man, stress at work and at home, increased loads and the associated responsibility - all this leads to mental exhaustion and moral burnout.

In our country, psychoanalysis is not as popular as in the West, so it is easier to diagnose yourself and prescribe treatment in accordance with Internet recommendations.

When choosing antidepressants you need to be very careful! Even herbal medications, which cannot be called antidepressants in the full sense, have a list of side effects.


Medications, usually:

  • Contraindicated for children and adolescents;
  • Prohibited for pregnant women;
  • Not recommended during breastfeeding;
  • Use with caution when chronic diseases internal organs, endocrine diseases, mental disorders

In many cases, during treatment depressive states associated with the decline vitality, lethargy, melancholy, apathy, irritability, sleep disturbances can be treated with “light artillery”: sedatives, immunomodulatory drugs.

In cases where clinical picture causes concern, you should seek help from a specialist. Most “serious” drugs are sold in pharmacies with a doctor’s prescription.

After an examination and history taking, he will be able to decide what medications are needed in a particular case, in what dosage and for how long.

Separate medications should not be discontinued abruptly; the dose must be reduced gradually.

Depression interferes with socialization and adaptation, disrupts the usual rhythm, changes a person’s mood, character and habits.

For minor disorders, you can purchase good over-the-counter antidepressants. But in case of severe violations, competent medical assistance is necessary.

Stress and depression have taken over modern humanity so much that many people use antidepressants as food or dessert. However, few people know what the best and strongest antidepressants are today, available without a prescription from a psychotherapist, what effect they have on the psyche and brain biochemistry, and also what side effects different antidepressants have.

To your attention, dear visitors of the site of psychological assistance http://site, new generation antidepressants are presented - a list of drugs.

Safe strong antidepressants - names

Any strong antidepressants, including the so-called “safe” ones, are drugs (essentially psychotropics) that mainly affect the level of serotonin, dopamine and norepinephrine (neurotransmitters) in the biochemistry of the brain in depressive and stress disorders.

It is precisely when the listed “hormones of joy” are reduced, often during stress, emotional and mental stress, psychological trauma, etc. the person may experience depression. Strong safe antidepressants help improve mood, remove sadness, anxiety, restlessness and irritability, they improve sleep phases and make a person more productive.

Antidepressants have different names, most often these are trade marks, behind which the general may be hidden international name one or another antidepressant drug.

The best antidepressants - a list of new generation drugs

Many of the best new generation antidepressants are available without a doctor's prescription and mainly contain various herbs and other natural substances. However, this does not mean at all that they are completely safe and can really save a person from depression once and for all.

Antidepressants - list of new generation drugs:

  • Paroxetine (Paxil)
  • Sertraline (Aleval)
  • Citalopram (Oprah)
  • Tianeptine (Coaxil)
  • Venlafaxine (Velaxin)
  • Opipramol
  • Mianserin (Lerivon)

Natural, herbal antidepressants

The main natural herbal antidepressants:

  • Schisandra tincture
  • Hawthorn tincture
  • Ginseng tincture
  • Leuzea extract
  • Valerian tincture

Tricyclic antidepressants

Tricyclic antidepressants - list of drugs:

  • Rimipramine
  • Imipramine
  • Clomipramine
  • Desipramine
  • Fluoroacyzine
  • Northliptilin
  • Protlitilin
  • Tofranil
  • Elavil
  • Trimipramine
  • Azafen
  • Saroten Retard
  • Clofranil
  • Doxepin
  • Melipramine
  • Anafranil
  • Maprotiline

What's better than taking antidepressants? Psychotherapy and psychotraining

Even the best and safest antidepressants have side effects in one way or another; moreover, they do not treat the disease itself, do not remove the source of depression or stress, but only relieve symptoms, temporarily improving a person’s emotional and mental state.


After stopping antidepressants, a “withdrawal syndrome” may occur and depression may soon return in an even more severe form.

Antidepressants should be taken only in crisis situations, and when the condition improves, resort to non-drug psychotherapy and psychological trainings. Only in this case is it possible to get rid of the very source of depression and carry out antidepressant prevention for the future.

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