Is glycine the safest medicine? Instructions for use glycine

Pills

Pharmacotherapeutic group

A drug that improves brain metabolism

Pharmacological properties

Refers to replaceable amino acids. According to modern data, it is a central neurotransmitter (transmitter nervous excitement) braking type of action. Renders sedative effect(calming effect on the central nervous system). Improves metabolic processes ( metabolic processes) in brain tissue. Renders positive influence at muscular dystrophies(decreased muscle volume and strength).

Indications for use Glycine

- alcoholism;

Reduced mental performance;

Stressful situations - psycho-emotional tension (during exams, conflict situations);

Deviant forms of behavior in children and adolescents;

Various functional and organic diseases of the nervous system, accompanied by increased excitability, emotional instability, decreased mental performance and sleep disturbances (neuroses, neurosis-like states and vegetative-vascular dystonia, consequences of neuroinfections and traumatic brain injury, perinatal and other forms of encephalopathy (including alcoholic origin);

Ischemic stroke.

Contraindications

Hypersensitivity to glycine.

Cautions for use

In patients with a tendency to arterial hypotension doses should be reduced and blood pressure monitored; if blood pressure decreases, the use of glycine should be discontinued

Interactions with drugs

Reduces toxic effect anticonvulsants and antipsychotics, antidepressants.

When combined with sleeping pills, tranquilizers and neuroleptics summarize the effect of inhibition of the central nervous system.

Directions for use and dosage Glycine

Glycine is prescribed in the form of tablets (0.1 g) under the tongue.
Sick chronic alcoholism when stopping (removing) binge drinking, 1 tablet of the drug is prescribed, then after 20 minutes - a second, after 60 minutes - a third, and then 1 tablet 3-4 times during the day. The total daily dose is 0.6-0.7 g.

For hangover syndrome, the drug is used for 5-7 days, 1 tablet 2 times a day, and subsequently (as a course treatment) for 6-15 days, 1 tablet in the morning. The course dose is 2.8-4.2 g.

During the period of remission (temporary weakening or disappearance of the manifestations of the disease) in the presence of anxiety, depressive disorders, increased irritability glycine take 1 tablet 2-4 times a day, and for sleep disorders - 1 tablet 20 minutes before bedtime. With symptoms of excitement and simultaneous craving for alcohol, during the period of acute alcohol intoxication Prescribe 1 tablet of the drug, and if necessary, a second tablet with an interval of 15-20 minutes.

Glycine is applied sublingually or buccally at 100 mg (in tablets or in powder form after crushing the tablets).

For practically healthy children, adolescents and adults with psycho-emotional stress, decreased memory, attention, mental performance, delay mental development, for deviant forms of behavior Glycine is prescribed 1 tablet. 2-3 times/day for 14-30 days.

With functional and organic lesions of the nervous system, accompanied by increased excitability, emotional lability and sleep disturbances, children under 3 years of age are prescribed 0.5 tablets. (50 mg) 2-3 times/day for 7-14 days, then 50 mg 1 time/day for 7-10 days. Daily dose- 100-150 mg, course course - 2-2.6 g.

Children over 3 years of age and adults are prescribed 1 tablet. 2-3 times/day, course of treatment - 7-14 days. The course of treatment can be increased to 30 days; if necessary, the course is repeated after 30 days.

For sleep disorders, prescribe 0.5-1 tablet 20 minutes before bedtime or immediately before bedtime. (depending on age).

With ischemic cerebral stroke during the first 3-6 hours from the onset of stroke, 1 g is prescribed transbuccally or sublingually with 1 teaspoon of water, then - for 1-5 days, 1 g / day, then over the next 30 days, 1-2 tablets. 3 times/day.

In narcology, Gglycine is used as a drug that increases mental performance and reducing psycho-emotional stress during the period of remission in cases of encephalopathy, organic lesions of the central and peripheral nervous system, 1 tablet. 2-3 times/day for 14-30 days. If necessary, courses are repeated 4-6 times a year.

The processes occurring in the human body are closely interconnected. All substances that are inside us are necessary and perform a specific function. Amino acids are integral part proteins - the main " building material» organism. They can be either irreplaceable or replaceable. The first are distinguished by the fact that they can only be produced endogenously. Nonessential amino acids can be introduced into the body from the outside, that is, with food or in the form of synthetic analogues. A striking example Glycine serves as such a substance. The side effects of this drug are minimal, so it is produced in the form of tablets and is dispensed without a special prescription from a doctor.

Action of glycine in the body

Due to the fact that glycine is a non-essential amino acid, our body needs it. Its deficiency can lead to severe conditions, therefore, a synthetic analogue was developed that is easily absorbed and replenishes its deficiency. In addition to the fact that glycine is an integral part of the body’s proteins, it at the same time performs another important function. It consists in its inhibitory effect on the nervous system. Based on this, glycine is one of the neurotransmitters that is on a par with adrenaline, acetylcholine and GABA. It has sedative, antidepressant and antioxidant effects. In addition, glycine improves metabolism in the brain. The amino acid acts at the cellular level, delivering oxygen to the tissues of the body. The use of the drug "Glycine" reduces the toxic effect of other drugs.

Indications for use

Due to its effects, glycine is prescribed for various diseases brain. It can be used at any age, including the neonatal period. The only contraindication is an allergy to glycine, which occurs in in rare cases. The drug is recommended for the following conditions:

1. Sleep disturbance.
2. Memory impairment.
3. Increased emotional excitability, neuroses.
4. Vegetovascular dystonia.
5. Brain injuries and diseases.
6. The period after a stroke.
7. Frequent alcohol intoxication.
8. Underachievement in children.

In the absence of these conditions, you can also use the drug "Glycine". The side effects of the medication are minimal, so it is also used to prevent stress.

Contraindications for use

The main contraindication to the use of the drug is increased sensitivity. In addition, when using the drug in patients with certain chronic diseases possible side effects. Glycine should not be used if you have sarcoidosis, Alzheimer's disease, intestinal obstruction, diarrhea, recent stomach bleeding, or kidney stones. In addition, the drug is contraindicated in patients with increased content calcium in the blood. Since glycine is an amino acid normally present in the body, it is safe to use during pregnancy and lactation.

The drug "Glycine": side effects

Hypersensitivity to the drug occurs in rare cases, but it is possible. In this case, various allergic reactions as skin rashes, edema. In some cases, dyspeptic disorders may occur when using the drug "Glycine". Side effects in the form of a decrease in blood pressure, increased heart rate and acidosis are observed extremely rarely, with a significant overdose of the drug. IN severe cases Symptoms such as heart pain and convulsive syndrome. Cupping side effects achieved by discontinuing the drug, as well as through symptomatic treatment.

From the point of view of pharmaceutical science, “Glycine” is a drug based on one of the amino acids - aminoacetic, which is also called aminoethane. Similar acids are produced by the human body with the help of the liver, however, if their quantity is insufficient, the situation can be corrected by taking the required substance.

Action of "Glycine"

The pharmaceutical effect is based on the fact that the amino acid it contains affects the functioning of one of the the most important parts- pituitary gland. As a result. Metabolic processes in the brain improve, which, in turn, leads to a general antidepressant effect on the body.

The doctor can prescribe the use of “Glycine” in the most various cases. For example, the group of common indications for its use includes a variety of stressful situations, which entail the emergence negative consequences such as insomnia, depressive state, irritability, decreased performance and others. Wherein this drug can be prescribed to both children, for example, when they display aggressiveness or symptoms of antisocial behavior.

However, in addition to eliminating common symptoms, which to one degree or another are characteristic of almost everyone to modern man, "Glycine" can also be used as medicine as part of complex therapy when treating more serious illnesses. Thus, it is used in the treatment of neuroses of various etiologies, as well as the consequences of neuroinfections, traumatic brain injuries and even strokes.

Side effects of Glycine

As is the case with any medicine, taking "Glycine" may lead to the occurrence of some unpleasant consequences, commonly called side effects. However, due to the fact that the action of “Glycine” is based on the content of an amino acid in it, identical to that which is independently produced human body, the nature and intensity of these side effects can be called minimal.

Thus, the drug contains mention of only one possible side effect from its use - the occurrence of allergic reactions, which may result from individual intolerance to the main or auxiliary components included in its composition. In addition, an additional effect when taking Glycine is that it reduces the intensity of the unpleasant side effects of other drugs that affect the nervous system.

To treat them, you can use Glycine.

Composition, release form, packaging

Basic chemical component represented by glycine. Note the following excipients:

• methylcellulose (water soluble);
• magnesium stearate.

The tablets are sweetish, their color is white, there are elements of marbling. The tablets are placed inside blister packs (50 pcs.). The records are contained inside a cardboard box. There are also instructions for use.

Manufacturer

Released in Russia. The drug is produced by LLC "Med Research and Production Complex "BIOTICS".

Indications for use

Discharged when:

• decline in mental performance;
• the presence of organic, functional diseases of the nervous system, which are accompanied by increased excitability, emotional instability,. Also the presence of consequences;
• stressful situations;
• deviant behavior, which is more often manifested in children and adolescents.

Contraindications

Hypersensitivity to any component of Glycine.

Interesting facts about the drug Glycine in our video:

Mechanism of action

The main component is endowed with the following effects:

• increased mental performance;
• normalization of sleep;
• making it easier to fall asleep;
• decline in aggressiveness;
• reduction of psycho-emotional stress;
• reducing the toxic effects of drugs. Typically, the toxic effect manifests itself in depression of central nervous system function;
• significant reduction in the manifestations of brain disorders that appear with ischemic stroke, traumatic brain injury;
• reduction of vegetative-vascular disorders.

Regulates metabolism, has an activating effect on protective inhibition (in the central nervous system), promotes its normalization, reduces psycho-emotional stress, and increases mental capacity.

The drug Glycine is capable of:

Instructions for use

Used sublingually, buccally. The dose is 100 mg. The drug is prescribed 1 tablet, taken 2 - 3 times a day. Therapy lasts approximately 14–30 days. This dose is indicated healthy patients who have:

• decreased attention;
• psycho-emotional stress;
• mental retardation;
• decreased mental performance.

If organic, functional lesions of the nervous system are accompanied by emotional lability, increased excitability, sleep disturbances, the dosage changes:

• Children under 3 years of age are given 50 mg, which is equal to 0.5 tablets. Frequency and duration of administration are the same as practically healthy people(2 – 3 times/day, 7 – 14 days). Then the child is given 50 mg once a day, 7 – 10 days;
• children from 3 years old, adults are given 1 tablet / 2 - 3 times a day, 7 - 14 days. If necessary, the course of therapy is increased to a month. After a month, the therapeutic course can be repeated.

If sleep disturbance is a concern, the drug should be taken before bedtime (20 minutes before bedtime). The dosage is 0.5 – 1 tablet.

If the patient has ischemic, you need to use the drug transbuccally, sublingually (the first 3 to 6 hours). The dosage is 1,000 mg. After this, you need to take 1,000 mg per day, 1 – 5 days. After this time, you need to take 1 - 2 tablets three times a day, for 30 days.

In the field of narcology, the medicine is used during remission in encephalopathy, the presence organic lesions Central nervous system, periphery. You need to use 1 tablet, 2-3 times/day, 14 – 30 days. If required, repeat the course 4–6 times a year.

Summary of the drug Glycine:

Side effects

Overdose

There is no data in the instructions. But experts say that an overdose of any medication has a bad effect on the body. In our case, the condition of patients who suffer from. With severe hypotension, the patient will feel:

Adults and elderly patients are prescribed "Glycine" to improve mood, improve concentration, and support performance.

During pregnancy, it is prescribed so that the expectant mother protects herself as much as possible from stress. Pills help suppress nervous excitability. Pregnant women are prescribed in the presence of NS disorders. Most often, expectant mothers are recommended to take 1 tablet three times a day. The duration of therapy is influenced by the health status of the expectant mother.

Drug interactions

There was a decrease in the manifestation of side effects from the following medications:

• anxiolytics;
• sleeping pills;
• antiseptic (neuroleptics);
• antidepressants;
• anticonvulsants.

Glycine is a popular nootropic drug, which has a mild sedative effect on the nervous system and improves mental activity. Due to its simple composition of components of natural origin, the side effects of glycine occur quite rarely and have a small range of manifestations, which allows the drug to be prescribed to adults and children.

Formulas and chemical description of glycine

The amino acid is recommended for prevention nervous overstrain before potential exposure to stress factors (when moving, during exams, changing jobs, etc.), to reduce the toxic effect when taking strong antidepressants and antipsychotics, and are also prescribed in the presence of the following indications:

• functional disorders of the nervous system ( vegetative-vascular dystonia, encephalopathy, limb tremors);
• insomnia;
• chronic overstrain after prolonged mental or physical stress;
• neuroses and stress;
• period after a stroke.

All information about in what cases glycine is prescribed is contained in the article.
There are few contraindications to taking the substance. As a rule, the instructions for use indicate a ban on the use of the drug only in case of individual intolerance to the amino acid, but doctors also advise limiting or eliminating the use of the drug in the following cases:

• Pregnancy. It is unknown how the drug can affect the fetus.
• Decreased arterial pressure. Acid can lower blood pressure even further, leading to drowsiness, increased heart rate, fainting and other negative reactions.
• Control vehicle. At an inappropriate dosage, glycine can cause drowsiness or a state of euphoria, which is dangerous for the driver.

Allergy to glycine

In case of individual intolerance to the drug, the body responds with the appearance of allergic reactions: from swelling and tearfulness to itchy skin rashes and anaphylactic shock.

To avoid the development of allergies in the first days, the substance should be consumed in reduced doses, observing the body’s reaction.

Sometimes patients have a question about whether there may be an allergy to the drug if there is no individual intolerance to aminoacetic acid. The answer is yes, this is due to excipients– magnesium stearate and methylcellulose, which also have some risk of allergic reactions.

In some cases, the remedy causes side effects, the opposite of the expected effect: glycine causes headaches, insomnia, emotional agitation instead of calm. Such manifestations serve as a signal to stop taking the drug and additional consultation with a doctor. In some cases, side effects are associated with incorrect diagnosis based on symptoms and incorrect prescription of the drug.

Glycine: is it possible to become addicted?

The drug does not contain components foreign to the human body, does not accumulate in tissues, quickly disintegrates into water and carbon dioxide, so the answer to the question “is glycine addictive?” – negative.

The mechanism of action of the amino acid is identical to the natural transport of aminoacetic acid in the blood, so chemical dependence on glycine is also impossible.

However, if the recommended course of use of the drug is exceeded, negative reactions may occur (depression, increased drowsiness, headache etc.) which in a simplified form can be explained by the fact that glycine is addictive.

These reactions are associated with overload of the nervous system, which regularly experiences the effects of natural and additional glycine. Therefore, the course of treatment with this remedy lasts no more than 2-4 weeks and there is a break of at least 1 month between courses.

Important! Special negative impact Exceeding the course of taking the drug affects the child’s nervous system, which is less stable than that of adults. In this regard, by the third week of administration, the dosage of glycine is reduced.

Glycine has a fairly large limit daily norm consumption - up to 3.5 g. About 2 g of the substance is produced in the body as a result of digestion of food and other metabolic reactions, and with the drug, depending on the treatment regimen, from 300 mg to 1 g of amino acid per day is supplied, which theoretically makes an overdose of the substance impossible.
However, if the recommended dosages and duration of treatment are systematically exceeded, we're talking about about glycine poisoning.

Symptoms of substance poisoning:

• severe dizziness;
• critical decrease in blood pressure;
• dry mouth;
• impaired coordination, in which the sense of space is lost;
• severe weakness, apathy, lack of emotional reaction to any irritation;
• cutting attacks of headache.

If there are symptoms of an overdose, you must immediately stop taking the drug, rinse the victim’s stomach, and provide drinking plenty of fluids and, if possible, raise blood pressure (for example, with coffee).

In general, the practice of glycine use among patients of different ages did not reveal long-term negative reactions. Numerous responses real people You can read about the drug and what effect the use of the substance gives in the article.

Thus, by taking glycine according to indications in recommended doses, you will be able to prevent possible side effects as much as possible, receiving all the necessary benefits of the drug.

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