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Furazolidone similar drugs. Furazolidone - official instructions for use


Analogues of the drug furazolidone are presented, in accordance with medical terminology, called “synonyms” - drugs that are interchangeable in their effects on the body, containing one or more identical active ingredients. When selecting synonyms, consider not only their cost, but also the country of production and the reputation of the manufacturer.

Description of the drug

Furazolidone- Antimicrobial agent, nitrofuran derivative. Active against gram-negative bacteria (including Shigella spp., Salmonella spp.), some gram-positive bacteria, as well as Trichomonas vaginalis, Giardia lamblia.

List of analogues

Note! The list contains synonyms for Furazolidone, which have a similar composition, so you can choose a replacement yourself, taking into account the form and dose of the medicine prescribed by your doctor. Give preference to manufacturers from the USA, Japan, Western Europe, as well as well-known companies from of Eastern Europe: KRKA, Gedeon Richter, Actavis, Aegis, Lek, Hexal, Teva, Zentiva.


Reviews

Below are the results of surveys of site visitors about the drug furazolidone. They reflect personal feelings surveyed and cannot be used as an official recommendation for treatment with this drug. We strongly recommend that you contact a qualified medical specialist to select a personal course of treatment.

Visitor survey results

Two visitors reported effectiveness

Participants%
Effectively2 100.0%

Your answer about efficiency »

Visitor Report of Side Effects

Your answer about side effects »

One visitor reported an estimate of the cost

Participants%
Not expensive1 100.0%

Your answer about the cost estimate »

Two visitors reported frequency of intake per day

How often should you take Furazolidone?
Most respondents most often take this drug 3 times a day. The report shows how often other survey participants take this drug.
Your answer about dosage »

Three visitors reported an expiration date

How long does it take to take Furazolidone to feel an improvement in the patient’s condition?
Survey participants in most cases felt an improvement in their condition after 5 days. But this may not correspond to the period after which you will begin to improve. Check with your doctor for how long you need to take this medicine. The table below shows the results of the survey on the initiation of effective action.
Participants%
5 days1 33.3%
1 day1 33.3%
1 month1 33.3%

Your answer about the start date »

Visitor report on reception time

Information has not yet been provided
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Eighteen visitors reported the patient's age


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Official instructions for use

There are contraindications! Read the instructions before use

Instructions
By medical use.drug

Furazolidone

Registration number LSR-004228/09-280509
Tradename: Furazolidone

International nonproprietary name:

Furazolidone

Dosage form:

pills

Compound:


1 tablet contains:
Active substance- Furazolidone - 0.05 g
Excipients - potato starch - 0.02 g
  • calcium stearate (calcium stearate) - 0.001 g
  • sugar (sucrose) - 0.01 g
  • Tween-80 (polysorbate) -0.0002 g
  • lactose (milk sugar) - 0.0188 g
    Description:
    Tablets are yellow or greenish-yellow, flat-cylindrical with a bevel.

    Pharmacotherapeutic group:

    Antimicrobial and antiprotozoal agent.
    ATX code: G01AX06
    Pharmacodnnamnka
    Antimicrobial agent, derivative of nitrofurans. Active against gram-positive and gram-negative microbes, Trichomonas spp., Ciardia lamblia. The most sensitive to furazolidone are Shigella dysenteria spp., Shigella flexneri spp., Shigella boydii spp., Shigella sonnei spp.. Salmonella typhi, Salmonella paratyphi. Weak effect on pathogens of purulent and anaerobic infection. Microbial resistance develops slowly. Blocks monoamine oxidase.
    Nitrofurans disrupt the processes of cellular respiration of microorganisms, suppress the tricarboxylic acid cycle (Krebs cycle), and also inhibit biosynthesis nucleic acids microorganisms, resulting in the destruction of their shell or cytoplasmic membrane. As a result of the action of nitrofurans, microorganisms produce fewer toxins, and therefore an improvement in the patient’s general condition is possible even before a pronounced suppression of microflora growth. Unlike many other antimicrobial drugs, they not only do not inhibit, but even activate immune system body (increase complement titer and the ability of leukocytes to phagocytose microorganisms).

    Pharmacokinetics

    Well absorbed when administered orally. Against the background of inflammation meninges concentrations are created in the cerebrospinal fluid equal to those in the plasma. It is quickly and intensively metabolized mainly in the liver with the formation of a pharmacologically inactive metabolite (amino derivative). Excreted mainly by the kidneys (65%), small amounts are found in feces, where therapeutic concentrations are achieved against intestinal pathogens
    Indications for use
    Dysentery, paratyphoid fever, giardiasis, food toxic infections.

    Contraindications

    Pregnancy, lactation. Increased individual sensitivity to the nitrofuran group. Terminal stage chronic renal failure, glucose-6-dehydrogenase deficiency, childhood up to 3 years (for this dosage form).
    Carefully
    Chronic renal failure, glucose-6-phosphate dehydrogenase deficiency, liver disease and nervous system.

    Directions for use and doses

    Inside, after eating. For dysentery, paratyphoid fever and foodborne diseases- 100-150 mg 4 times a day (but not more than 800 mg), for 5-10 days.
    For giardiasis: adults - 100 mg 4 times a day, children - 10 mg/kg/day, dividing the daily dose into 3-4 doses. The highest single dose for adults is 200 mg; daily - 800 mg.

    Side effects

    Decreased appetite, up to anorexia; nausea, vomiting; allergic reactions (skin rash, hyperemia and itching of the skin, angioedema). At long-term use- neuritis.
    Overdose (intoxication) of the drug
    Symptoms: acute toxic hepatitis, hematotoxicity, neurotoxicity (polyneuritis). Treatment: drug withdrawal, administration large quantity liquids, symptomatic therapy, antihistamines, B vitamins.

    Interaction with other drugs

    Furazolidone in combination with ethanol can lead to the development of disulfiram-like reactions, and therefore their simultaneous use is not recommended.
    Antidepressants, monoamine oxidase inhibitors, ephedrine, amphetamine, phenylephrine, tyramine may cause sharp increase blood pressure.

    special instructions

    Increases inhibition of hematopoiesis against the background of chloramphenicol and ristomycin. Increases sensitivity to the action of ethanol. Medicines, alkalizing urine reduces the effect, while acidifying ones increase it.
    Aminoglycosides and tetracycline enhance antimicrobial properties.
    During treatment, precautions must be taken, as when using monoamine oxidase inhibitors, namely: exclusion from the diet of foods containing tyramine: cheese, cream, beans, pickled herring, strong coffee. To prevent neuritis with long-term use, it must be combined with B vitamins.

    Release form

    Pills. 50 mg.
    10 tablets in cell-free packaging. 50 tablets per orange glass jar.
    800 contour cellless packages or 240 cans with an equal number of instructions for use are placed in a cardboard box (for hospitals).

    Storage conditions

    List B.
    In a dry place, protected from light. Keep out of the reach of children.

    Best before date

    3 years.
    Do not use after the expiration date.

    Vacation conditions

    Over the counter.

    Manufacturer

    OJSC "Irbit Chemical and Pharmaceutical Plant" 623800, Sverdlovsk region, Irbit, st. Kirova, 172

    The information on the page was verified by physician-therapist E.I. Vasilyeva.

  • LSR-004228/09

    Trade name of the drug:

    FURAZOLIDONE

    INN or group name:

    Furazolidone

    Dosage form:

    pills

    Compound:

    1 tablet contains:
    active substances: furazolidone – 0.05 g;
    Excipients:- potato starch – 0.02 g, calcium stearate (calcium stearate) – 0.001 g, sugar (sucrose) – 0.01 g, Tween-80 (polysorbate) – 0.0002 g, lactose (milk sugar) – 0.0188 G

    Description:
    Tablets are yellow or greenish-yellow, flat-cylindrical with a bevel.

    Pharmacotherapeutic group:

    Antimicrobial and antiprotozoal agent.

    ATX code: G01AX06

    Pharmacological properties

    Pharmacodynamics
    Antimicrobial agent, derivative of nitrofurans. Active against gram-positive and gram-negative microbes, Trichomonas spp., Giardia lamblia. Most sensitive to furazolidone S higella dysenteria spp., Shigella flexneri spp., Shigella boydii spp., Shigella sonnei spp., Salmonella typhi, Salmonella paratyphi. Has little effect on pathogens of purulent and anaerobic infections. Microbial resistance develops slowly. Blocks monoamine oxidase.
    Nitrofurans disrupt the processes of cellular respiration of microorganisms, suppress the tricarboxylic acid cycle (Krebs cycle), and also inhibit the biosynthesis of nucleic acids of microorganisms, resulting in the destruction of their membrane or cytoplasmic membrane. As a result of the action of nitrofurans, microorganisms produce fewer toxins, and therefore an improvement in the patient’s general condition is possible even before a pronounced suppression of the growth of microflora. Unlike many other antimicrobial drugs, they not only do not inhibit, but even activate the body’s immune system (increase the complement titer and the ability of leukocytes to phagocytose microorganisms).

    Pharmacokinetics
    Well absorbed when administered orally. Against the background of inflammation of the meninges, concentrations are created in the cerebrospinal fluid equal to those in the plasma. It is quickly and intensively metabolized mainly in the liver with the formation of a pharmacologically inactive metabolite (amino derivative). It is excreted mainly by the kidneys (65%), small amounts are found in feces, where therapeutic concentrations are achieved against pathogens of intestinal infections.

    Indications for use

    Dysentery, paratyphoid fever, giardiasis, food toxic infections.

    Contraindications

    Pregnancy, lactation. Increased individual sensitivity to the nitrofuran group. End-stage chronic renal failure, glucose-6-phosphate dehydrogenase deficiency, children under 3 years of age (for this dosage form).

    Carefully: chronic renal failure, glucose-6-phosphate dehydrogenase deficiency, liver and nervous system diseases.

    Directions for use and doses

    Inside, after eating. For dysentery, paratyphoid fever and food poisoning - 100-150 mg 4 times a day (but not more than 800 mg), for 5-10 days.
    For giardiasis - adults - 100 mg 4 times a day, children - 10 mg/kg/day, dividing the daily dose into 3-4 doses.
    The highest single dose for adults: 200 mg, daily - 800 mg.

    Side effect

    Decreased appetite, up to anorexia; nausea, vomiting; allergic reactions (skin rash, hyperemia and itching of the skin, angioedema).
    With long-term use - neuritis.

    Overdose

    Symptoms: acute toxic hepatitis, hematotoxicity, neurotoxicity (polyneuritis).
    Treatment: drug withdrawal, taking large amounts of fluid, symptomatic therapy, antihistamines, B vitamins.

    Interaction with other drugs Furazolidone in combination with ethanol can lead to the development of disulfiram-like reactions, and therefore their simultaneous use is not recommended.
    Antidepressants, monoamine oxidase inhibitors, ephedrine, amphetamine, phenylephedrine, tyramine can cause a sharp increase in blood pressure.

    special instructions

    Increases inhibition of hematopoiesis against the background of chloramphenicol and ristomycin.
    Increases sensitivity to the action of ethanol. Medicines that alkalize urine reduce the effect, while those that acidify urine increase it.
    Aminoglycosides and tetracycline enhance antimicrobial properties.
    During treatment, precautions must be taken, as when using monoamine oxidase inhibitors, namely: exclusion from the diet of foods containing thiamine: cheese, cream, beans, pickled herring, strong coffee.
    To prevent neuritis with long-term use, it should be combined with B vitamins.

    Release form

    Tablets 50 mg.
    10 tablets per blister pack.
    50 tablets per jar from polymer materials.
    1, 2, 3, 4 or 5 blister packs or 1 jar of polymer materials with instructions for medical use in a cardboard pack.

    Storage conditions

    Store in a dry place, protected from light.
    Keep out of the reach of children.

    Best before date

    3 years.
    Do not use after the expiration date.

    Conditions for dispensing from pharmacies

    Over the counter.

    Manufacturer/organization accepting claims
    LLC Anzhero-Sudzhensky Chemical and Pharmaceutical Plant.
    652473, Russia, Kemerovo region, Anzhero-Sudzhensk, st. Herzen, 7,

    Furazolidone is an antibacterial agent and is used to combat poisoning. It is effective against infections genitourinary system, gastrointestinal tract and giardiasis. Unanimously recognized by doctors as safe and effective medicine Furazolidone is approved for use in the treatment of poisoning in children of various ages. We’ll talk about what the drug is and in what cases Furazolidone can be used for children.

    Furazolidone – medicinal product from the group of nitrofurans, possessing antibacterial properties

    Description of Furazolidone

    Furazolidone is part of the group of nitrofurans, which have a destructive effect on the life processes of pathogenic microbes. The working substance is furazolidone, which gives the product its name. In addition, it contains lactose monohydrate, calcium stearate, silicon dioxide, potato starch.

    Available in the form of tablets (dragées) and granules; The content of the main substance is usually indicated on the packaging. For example, Furazolidone 50 means that one tablet contains 50 mg of the active ingredient. The drug is inexpensive: one blister of 10 tablets costs about 65 rubles, respectively, a package of two blisters costs 130 rubles.

    For children under 3 years of age, it is better to buy the drug in granules, from which a suspension is prepared; even infants can drink it. In order to know how much water to pour into the package, a measuring spoon is included. Children over 3-5 years old can be given tablets. The product is sold without a prescription, but it is not recommended to use it without consulting a doctor.

    In what cases is it used?

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    Parents should know exactly when to use Furazolidone. Full information on this issue is given in the instructions for the drug, but it is better to repeat it again and remember it.


    Furazolidone tablets are used for gastrointestinal infections of different nature

    Indications for use:

    The use of Furazolidone is permitted for children of any age, but with a precise indication of the problem that it should solve.


    Furazolidone can be used by children of any age, but only with the permission of a doctor

    Let's consider when to give medicine depending on the child's age:

    1. For infants, the drug helps in treatment infected burns and wounds. Sterile dressing moistened with Furazolidone and applied to the affected area.
    2. After one year of age, the medicine is given to babies in the form of a suspension for diarrhea and other disorders. It is prepared like this: take 100 ml of warm boiled water and pour it into a bottle with granules. When the drug dissolves, shake the bottle and give it to the child, observing the dosage.
    3. Children over 3-5 years old can take the product in tablets.

    Dosage Calculations

    What you should not do is resort to medication on your own. The correct dose and treatment tactics should be determined by a pediatrician.

    The doctor takes into account all factors: does the baby have chronic illnesses, what type of pathology is, how severe it is. In addition, when calculating the dose, the child’s weight is taken into account. General recommendation By daily dose– 10 mg of the drug per 1 kilogram of weight. These indicators mean that a 6-year-old preschooler weighing 20 kg should take 200 mg of Furazolidone per day, and a 6-month-old baby needs 60-70 mg.

    Treatment regimen

    Doctors have developed rules for taking medication for children and given nutritional recommendations for the period of treatment with Furazolidone. Parents should remember them well:


    Furazolidone must be washed down large quantity m of water
    • during a course of treatment, the drug should not be taken for more than 10 days;
    • frequency of administration per day – 4 times;
    • Furazolidone should be given after meals, with plenty of water;
    • It is necessary to reduce the amount of foods that contain tyramine in the child’s diet: smoked meats, canned food (meat and fish), chocolate, kefir, yogurt, cheese, legumes.

    The nutritional warning is due to the fact that the active substances of the drug, when interacting with tyramine, provoke negative processes. The child may feel dizzy, his blood pressure will increase, in some cases such negligence leads to severe consequences. Be sure to monitor your baby’s diet to prevent such problems.

    Contraindications

    The minimal toxicity of Furazolidone is the main argument that allowed pediatricians to prescribe the drug for rotavirus and other infections, even for one-year-old children. However, this quality does not negate the presence of contraindications for the medicine.


    There are a number of contraindications for which doctors prohibit the use of Furazolidone

    The drug is not used for:

    • end-stage chronic renal failure;
    • problems with the central nervous system;
    • lack of glucose-6-phosphate dehydrogenase;
    • individual intolerance to nitrofurans.

    Side effects

    The side effects of Furazolidone are also listed in the instructions; there are few of them, but they are there, which means they require careful attention from parents. It is necessary to monitor the child while giving him medicine. We list the main negative consequences:

    • allergies, manifested by itching, rash, swelling and redness;
    • gastrointestinal upset (vomiting, loss of appetite, nausea);
    • neuritis (forms with long-term use).

    Consequences of overdose

    It is difficult to overdose on a drug when you follow the prescribed dosage, but if information about this is in the instructions, then such cases have happened. Complications of overdose:


    An overdose of Furazolidone can lead to a number of complications.
    • methemoglobinemia and hemolytic anemia;
    • destruction of liver cells (hepatitis in acute toxic form);
    • disruption of the cellular composition of the blood and the functions of the cells themselves;
    • polyneuritis.

    What medications is the drug incompatible with?

    If there is a need to use Furazolidone, parents are required to inform the pediatrician what other medications the baby is taking at this time.

    The information is very important because Furazolidone is not compatible with some drugs. Let's list them:

    1. Ethanol. Association with this drug provokes acute intoxication, manifested by vomiting, headache, fever, nausea, problems with heart rhythm, difficulty breathing.
    2. Antidepressants and monoamine oxidase inhibitors. If the baby takes a medicine with phenylephrine, which constricts blood vessels, simultaneous use of Furazolidone will cause a sharp increase in blood pressure.
    3. Antibiotics of the aminoglycoside group can enhance antimicrobial effect Furazolidone.
    4. Foods and medications that can alkalize urine. Entering the body along with Furazolidone, they accelerate the process of drug elimination, reducing its therapeutic effectiveness.

    What analogues exist?

    Analogs that are structurally compatible with Furazolidone are not produced. There are tools similar to it therapeutic effect. The pediatrician decides which drug to replace the initial prescription, based on the diagnosis and nature of the causative agent of the disease.


    Smecta – safe drug for adults and children, which helps cope with gastrointestinal disorders and diseases

    If antibiotics are not required, the child is given Smecta; for a bacterial infection, the following substitutes are recommended:

    Product nameRelease formActive substanceIndicationsChild's age
    Enterofuril (more details in the article:)suspension and capsulesnifuroxazidediarrhea infectious nature in acute or chronic formsuspension - from 1 month, capsules from 3 years
    Naxojinpillsnimorazoletrichomonas infections, giardiasis, amebiasis; Vincent's gingivitis5 years and older
    Furadoninpillsnitrofurantoininfections urinary tract bacterial nature, prevention of intestinal infections during cystoscopy, catheterizationfrom 1st month
    Stopdiarpills; suspensionnifuroxazideacute and chronic diarrheaat 2-4 years capsules, suspension from 2 months
    Negroespillsnalidixic acidgastrointestinal infections; pyelonephritis; cystitis; urethritis; prostatitis; cholecystitis.from 2 years

    Furazolidone is effective against various infections and has a multi-level effect. Pediatricians note its low toxicity, but it also has contraindications and side effects that lead to serious complications. Obviously, with such characteristics, the drug should not be used independently. The decision to use it should be made by a specialist, a doctor who can properly structure treatment and avoid negative consequences.

    An antibacterial agent that is used primarily in urology. Effectively fights the causative agent of the disease and rarely causes adverse reactions. Children are prescribed in the form of a suspension, which also has a detrimental effect on pathogenic flora in the gastrointestinal tract.

    Dosage form

    Furazolidone is available in tablets. The package with the drug contains 2 blisters of 10 tablets each. For children, the medicine can be prescribed in the form of a granulated powder for the preparation of a suspension.

    Description and composition

    The drug Furazolidone belongs to the antibacterial drugs from the nitrofuran group. My high efficiency the drug has proven to treat many infectious diseases. It has a broad antimicrobial effect, is highly effective, well tolerated and has low toxicity. In practice, Furazolidone is more often used in nephrology, urology, gastroenterology or dermatology. Compared to other antibiotics, the drug is affordable. Furazolidone does not have structural analogues, therefore, the medicine can only be replaced with antibiotics with the same principle of action.

    One tablet of the drug contains 0.05 g of furazolidone, as well as excipients.

    Pharmacological group

    Furazolidone – antimicrobial drug from the group of nitrofurans. The use of tablets in the treatment of infectious diseases makes it possible to suppress the aggressiveness and reproduction of a large number of pathogenic bacteria, including gram-positive and gram-negative bacteria, as well as trichomonas, salmonella. It is these bacteria that most often cause the development of diseases of the genitourinary system. The drug does not show high activity against anaerobic and purulent infections. The mechanism of action of the drug allows you to disrupt breathing pathogenic bacteria at the cellular level, suppress their reproduction cycle, inhibit their biological processes. This action of the drug allows you to destroy the membrane of bacteria, stop their reproduction and penetration into the deeper tissues of the body. Under the influence of the drug, there is a decrease in toxins produced by bacteria. This effect of the drug allows you to improve general state patient, reduce the risk of developing intoxication of the body with waste products of bacteria.

    Furazolidone is a synthetic antibiotic. When used, a pronounced bacteriostatic effect is manifested, as well as persistent antimicrobial effect. The drug destroys the integrity cell membranes bacteria, blocks their growth and reproduction, thereby reducing the risk of complications and speeding up recovery.

    Indications for use

    The instructions for the drug contain a list of diseases, the treatment of which may include taking Furazolidone tablets. The appropriateness of prescribing the drug should be determined by the doctor.

    For adults

    For adults, Furazolidone tablets are prescribed in complex therapy with other drugs to treat the following diseases and conditions:

    • infectious diarrhea;
    • enterocolitis;
    • giardiasis;
    • food toxic infections.

    For children

    In pediatrics, the medicine is prescribed in the form of granules to prepare a suspension for oral administration. The following conditions may be indicated:

    Only a doctor can prescribe the drug to a child strictly according to indications, individually selecting the dosage of the drug.

    During pregnancy and breastfeeding It is better to avoid using Furazolidone tablets. Clinical trials not identified negative impact drug on the fetus, so in some cases, when there is a need to take medication, it can be prescribed by a doctor. Pregnant women can be prescribed tablets for: intestinal infection x, giardiasis and other diseases.

    Clinical trials have shown that in in rare cases taking medication by a pregnant woman can provoke glucose-6-phosphate dehydrogenase deficiency in the child, hemolytic anemia and other conditions. Considering possible risks, only a doctor can prescribe medicine.

    Contraindications

    Like any other antibiotic, Furazolidone has a number of contraindications, including:

    1. increased sensitivity to the composition;
    2. chronic renal failure;
    3. pregnancy;
    4. breast-feeding;
    5. children under 1 year of age.

    The medicine is prescribed with caution in case of deficiency of the enzyme glucose-6-phosphate dehydrogenase, pathologies of the nervous and cardiovascular systems.

    Applications and dosages

    The antimicrobial drug Furazolidone can be prescribed by a doctor only after determining the cause of the disease and making a diagnosis. Doses are determined by the doctor individually for each patient.

    For adults

    Furazolidone tablets are taken strictly following the prescribed regimen. Depending on the diagnosis and stage of the disease, the dose may be increased or decreased. Standard scheme The dose is considered to be 2 tablets 3 times a day. The treatment course can take from 3 to 7 days. The effect of taking the drug can be noticed already on the 2nd day of use.

    For children

    For children, a suspension is used. At the age of 1 to 3 years, a single dose of 0.0125 g - 0.015 g (4 - 5 ml) per day is prescribed. Children from 3 to 5 are recommended to take 0.018 - 0.021 g (6 - 7 ml) per day. From 5 years old, no more than 0.084 g (24 - 28 ml) per day is allowed. Along with the bottle, the package contains a measuring spoon, which allows parents to correctly distribute doses of the medicine and eliminate the risk of overdose.


    For pregnant women and during lactation

    Considering that the drug is contraindicated in pregnant women and can only be used in as a last resort, the dosage should be prescribed by a doctor individually for each woman.

    Side effects

    The drug Furazolidone has slight toxicity, is well tolerated, but can still cause some adverse reactions in the body, including:

    • decreased appetite;
    • nausea, urge to;
    • allergic skin reactions;
    • pain in the epigastric region.

    The appearance of such symptoms often becomes a reason to discontinue the drug and prescribe analogues. The closest analogues in terms of the mechanism of action are such drugs as Enterol, Enterofuril. Such drugs contain other active ingredient, therefore only a doctor can prescribe them.

    Interaction with other drugs

    Furazolidone, antibacterial drug, therefore it is not compatible with similar groups of drugs. Taking drugs from the tetracycline group enhances the effect of furazolidone, which increases the risk side effects. At joint reception drug and drugs from the group of antidepressants, monoamine oxidase inhibitors, ephedrine, may increase blood pressure. The drug is not compatible with alcohol. If a person has chronic diseases, is taking any medications, you must inform your doctor about this.

    special instructions

    It is strictly forbidden to take the drug without a doctor's prescription. Only a specialist will be able to prescribe the required dose and therapeutic course. If the nature of the disease is not known, it is recommended to undergo additional methods research and only then take the drug.

    Overdose

    If the prescribed dose of the drug is not observed or if it is used uncontrolled, there is a risk of developing adverse reactions of the body, including:

    1. acute toxic hepatitis;
    2. polyneuritis;
    3. symptoms of poisoning.

    There is no antidote for such symptoms and consequences, so only going to the hospital, taking enterosorbents and saline laxatives can improve the patient’s condition.

    Storage conditions

    You can buy medicine at a pharmacy without a doctor's prescription, although the instructions contain information about prescription drug. The medicine should be stored in a dark place inaccessible to children at a temperature not exceeding 25 degrees. The shelf life of the medicine is 3 years from the date of release.

    Furazolidone is a cheap antibiotic. He has good feedback from users, but can only be used as prescribed by a doctor.

    Analogues

    The following furazolidone analogues are commercially available:

    1. represents antibacterial agent, which acts predominantly in the intestinal lumen. Therefore it is prescribed for bacterial infections flowing in this department digestive tract. The medication is available in tablets that can be taken by children from 3 years of age.
    2. belongs to Furazolidone substitutes in the clinical and pharmacological group. It is an intestinal antiseptic, its active substance is . The drug comes in tablets, capsules and suspensions. It is used for intestinal infections caused by pathogens sensitive to it in children over 2 years of age. Can be used with caution during pregnancy and lactation.
    3. refers to nitrofuran derivatives. The medication is available in tablets that contain nifuratel as an active ingredient. It has antibacterial, antimycotic, antiprotozoal effects. The medication is used for infections of the genitourinary system and digestive tract. For children it is prescribed at a dosage of 10-15 mg per kg of weight. You can drink with caution during pregnancy and lactation.
    4. belongs to Furazolidone substitutes in the therapeutic group. It is available in capsules and suspensions. Used as antimicrobial agent for intestinal infections. In suspension, the drug can be given to babies older than 1 month; capsules are allowed from 3 years. It can be used for a short time during lactation.

    Drug price

    The cost of Furazolidone is on average 80 rubles. Prices range from 48 to 203 rubles.

    Furazolidone belongs to the nitrofuran group of antibiotics. The instructions for use indicate that this drug is used in the treatment of a number of diseases. This:

    • Dysentery and salmonellosis;
    • typhus and paratyphoid;
    • cholera;
    • giardiasis;
    • food poisoning;
    • trichomonas lesions of the genitourinary system;
    • cystitis;
    • treatment infected wounds using the drug topically.

    Many of the above pathologies have diarrhea as their main symptom. But there is also infectious lesions internal organs and systems.

    Furazolidone has limited effectiveness against fungal flora. In addition, the product has a number of contraindications. Therefore, the question arises: what to replace Furazolidone with?

    Let's make a list of substitutes for a familiar drug.

    The phenomenon is familiar to both adults and children. There are many causes of diarrhea - from banal overeating or errors in diet to serious organ pathologies gastrointestinal tract. Consequently, there are many drugs that act on this unpleasant symptom and are effective against various pathogens.

    Furadonin’s “brother” in the fight against diarrhea is Loperamide. This means, so to speak, is situational ambulance with diarrhea. After administration, the effect appears within 40-50 minutes.

    For effective disposal For diarrhea, it is recommended to immediately take two Loperamide tablets with plenty of water. Then one tablet after each loose stool, but not more than 10 tablets per day. After taking the drug, constipation and inhibition of intestinal motility are possible.

    If diarrhea does not go away within two days while taking Loperamide, you need to contact a specialist and change the drug. It is usually not prescribed in courses and has a number of contraindications.

    We already know that Furazolidone belongs to the antibiotic class of drugs, but it has a slight immunostimulating effect. In other words, it does not inhibit the beneficial microflora of the stomach and intestines. An analogue of Furazolidone in terms of its effect on beneficial microflora is the probiotic Enterol. It not only fights diarrhea, but is also recommended for simultaneous administration with tetracycline and cephalosporin antibiotics to avoid problems with the gastrointestinal tract.

    Therapy of other pathologies

    The instructions for use of the “hero of our novel” indicate not only the pathologies that cause stool disorders, but also some others. In this regard, there are also quite worthy analogues of Furazolidone. Let us consider them in relation to the pathologies for which they are prescribed.

    Inflammatory processes of the genitourinary system

    Since the highest concentration of Furazolidone is observed in the intestinal lumen, it is during intestinal infections that its effectiveness is maximum. But it is used for the treatment of cystitis as a mono-drug only in uncomplicated forms of the pathology.

    In the case of cystitis, if you choose which is more effective - Furazolidone or Furadonin, then the second drug works better. But it is more toxic and has a significant list of contraindications and side effects, including digestive disorders and dyspepsia.

    In this regard, the question of which is better, Furazolidone or Furagin, remains relevant:

    The next question is Furazolidone or Macmiror? These two drugs can be used interchangeably in the fight against such ailments:

    • Giardiasis;
    • pathologies of the urinary system.

    Macmiror is still indicated in treatment gynecological pathologies fungal and infectious origin, as well as inflammatory diseases upper sections Gastrointestinal tract.

    In the treatment of infected wounds, Furazolidone or Furacilin can be used as a local antiseptic. The difference between these drugs is that Furacilin is used only topically and has a limited range of applications. It is contraindicated for children under five years of age, pregnant and lactating women. With prolonged use, it can cause side reactions in the form of allergies, and if used for rinsing the mouth, angioedema is possible.

    None of the products are available with a prescription. But this does not mean that they can be used uncontrolled, and if any side effects occur while taking Furazolidone, you can independently replace the drug.

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