home Audience 1 What are these tablets for? Biseptol. Biseptol - a modern take on a long-familiar antibacterial drug

What are these tablets for? Biseptol. Biseptol - a modern take on a long-familiar antibacterial drug

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When is Biseptol indicated?

Toxoplasma; streptococci and staphylococci; protozoan microorganisms; toxoplasma; coli; pathogenic fungi.

Contraindications

Side effects

Biseptol - instructions for use, analogues, price, reviews

The drug Biseptol

Biseptol also has an effect on microorganisms that are resistant to other sulfonamide drugs.

Release forms

Tablets 120 mg (100 mg sulfamethoxazole and 20 mg trimethoprim);
Tablets 480 mg (400 mg sulfamethoxazole and 80 mg trimethoprim);
Tablets "Bactrim forte" 960 mg (800 mg sulfamethoxazole and 160 mg trimethoprim);
Syrup (or suspension) - for oral administration 100 ml (in 1 ml - 40 mg of sulfamethoxazole and 8 mg of trimethoprim);
Concentrate for the preparation of solution for injection 480 mg (in 1 ml of concentrate - 80 mg of sulfamethoxazole and 16 mg of trimethoprim).

The drug should be stored in a dry place and at a temperature not exceeding +25 o C.

Instructions for use of Biseptol

Indications for use

diseases respiratory tract(bronchitis in acute and chronic form; pneumonia; pleural empyema - purulent inflammation membranes of the lungs; abscess or abscess of the lung; bronchiectasis - dilation of the lumen of the bronchi due to disease);
ENT pathology (otitis, or inflammation of the ear; sinusitis, or inflammation of the paranasal sinuses);
intestinal infections (dysentery, paratyphoid A and B, cholera, typhoid fever);
infections of the genitourinary organs (urethritis - inflammation urethra; prostatitis – inflammation of the prostate gland; pyelonephritis – inflammation of the renal pelvis and the kidney tissue itself; salpingitis - inflammation of the uterine appendages);
gonorrhea (venereal disease);
infections of soft tissues and skin (pyoderma, or pustular skin lesions; acne; boil, or boil);
meningitis (inflammation meninges) and abscess (ulcer) of the brain;
septicemia (a form of blood poisoning);
infectious diseases: brucellosis, malaria, toxoplasmosis, borreliosis, scarlet fever;
wound infections and osteomyelitis;
prevention and treatment of Pneumocystis pneumonia in HIV-infected patients.

Contraindications

with severe cardiovascular insufficiency;
for diseases of the hematopoietic organs;
with liver failure;
with severe renal failure;
during pregnancy;
mothers when breastfeeding;
with deficiency of glucose-6-phosphate dehydrogenase (hereditary disease);
children under 3 months of age and premature babies;
with elevated bilirubin levels in children;
in case of hypersensitivity to the components included in the drug or to other sulfonamide drugs.

Biseptol can be used with caution if the patient has previously had allergies to other drugs; at bronchial asthma; patients with folic acid deficiency; for diseases of the thyroid gland; in the early childhood and in old age.

Side effects

From the digestive system: in rare cases - diarrhea, abdominal pain, loss of appetite, nausea, vomiting; in isolated cases - colitis (inflammation of the intestines); reactive inflammation of the liver with stagnation of bile – cholestatic hepatitis; glossitis - inflammation of the tongue; stomatitis – inflammation of the oral mucosa; pancreatitis – inflammation of the pancreas.
From the outside nervous system in some cases: dizziness, headache, depression, slight trembling of the fingers.
On the part of the kidneys in rare cases: increased volume of urine, inflammation of the kidneys (nephritis), bleeding in the urine.
From the respiratory system: bronchospasm, cough, suffocation or feeling of lack of air.
On the part of the hematopoietic organs in isolated cases: a decrease in the number of leukocytes in the blood, a decrease in the number of neutrophils (a type of leukocytes that protect the body from infections), a decrease in platelets (blood platelets involved in blood clotting), folate deficiency anemia.
From the skin: skin rashes in the form of urticaria; itching; in isolated cases - Lyell's syndrome and Stevens-Johnson syndrome (the most severe types of allergic manifestations on the skin and mucous membranes with necrosis and rejection); Quincke's edema (local or diffuse swelling of the subcutaneous tissue and mucous membranes); increased sensitivity to ultraviolet rays.
Isolated cases of chills and fever have been reported after taking Biseptol (drug fever).
Pain in joints and muscles.
Thrombophlebitis (at the injection site).
Reduced potassium, sodium and blood sugar levels.

Side effects are usually mild and disappear after discontinuation of the drug.

Treatment with Biseptol

Biseptol should be taken after meals. To prevent complications such as the formation of crystals in the urine and urolithiasis It is necessary to take the medicine with a sufficient amount of water, and ensure that you drink plenty of fluids (at least 2 liters per day) for the entire course of treatment.

Biseptol should not be taken simultaneously with Aspirin, Butadion, Naproxen.

The dose of the drug and duration of administration are prescribed by the doctor individually, depending on the severity of the condition and concomitant diseases.

Biseptol for children

Biseptol for sore throat

Biseptol for cystitis

Analogs and synonyms of Biseptol

Asacol (active ingredient: mesalazine);
Dermazin (active ingredient: sulfadiazine);
Inhalipt (active ingredients: streptocide, sodium sulfathiazole);
Ingaflu (active ingredient: streptocide) and other sulfonamide drugs.

Synonymous drugs are drugs with the same active ingredients, but have different names, because are produced by different companies. These are generic drugs. They may differ in dosage forms, but have the same pharmacological properties.

Reviews about the drug

Drug price

Biseptol tablets 120 mg - 20 pieces - 31 rub.

Biseptol tablets 480 mg - 20 pieces - 67 rub.

Biseptol in ampoules 480 mg (5 ml) - 10 pieces - 340 rub.

Biseptol suspension 80 ml (240 mg in 5 ml) – 120 rub.

What does Biseptol help with?

Biseptol is a widespread and quite effective antibacterial agent that helps cope with the manifestations of many infectious and inflammatory diseases of the body.

This drug is actively used in the treatment of acute or chronic inflammatory diseases of the respiratory, urinary, gastrointestinal and other systems.

The main active medicinal substance of this antimicrobial drug is sulfamethoxazole, which has a pronounced antibacterial effect against the most common infectious pathogens (staphylococci, streptococci, gonococci, etc.).

The effectiveness of treatment with Biseptol primarily depends on the severity and severity of the inflammatory disease of the body, while the average course of treatment with this drug is 5-7 days.

Main indications for use of Biseptol:

acute or chronic inflammatory diseases respiratory tract of the body (sore throat, tracheitis, bronchitis, pneumonia);
diseases genitourinary systems s (pyelonephritis, cystitis, prostatitis, urethritis);
infectious and inflammatory diseases of the gastrointestinal tract (diarrhea, dysentery, cholera);
otitis media (inflammation of the ear);
gonorrhea;
infectious lesions of the skin of the body (furunculosis, pyoderma);
meningitis (an acute infectious disease that affects the membranes of the brain).

Attention: before using Biseptol, you must consult with your physician in order to prevent the possible development of unwanted complications.

An antibacterial drug is produced in the form of tablets with different amounts of the active medicinal substance.

How to take Biseptol?

For adults daily dose Biseptol depends on the specific disease of the body and is 1-2 t. 2-3 r. daily after meals, with plenty of water.

The minimum interval between taking the drug should be 5-6 hours, while the average course of treatment with Biseptol is 5-7 days. Children from 3 to 6 years old this antibiotic prescribed ½ t. (mg.) 1-2 r. per day strictly as prescribed by the attending physician.

In case of sufficiently severe inflammatory diseases of the body ( acute bronchitis, pneumonia) the drug should be taken for at least 7-10 days, 1 t. (mg.) 2-3 r. the day after meals.

Contraindications to the use of Biseptol

increased individual sensitivity of the body to the main active ingredients of the drug;
acute renal failure;
pregnancy and lactation (breastfeeding);
stomach and duodenal ulcers;
serious illnesses liver;
severe inflammatory diseases of cardio-vascular system body.

Side effects of Biseptol

The most common adverse reactions from long-term use of this antibacterial drug are:

dry mouth;
digestive system disorders (diarrhea, nausea, flatulence, constipation);
dizziness (very rare);
skin itching;
headache;
decreased appetite;
allergic rash on the body (most often urticaria occurs).

If any of the above side effects develop, it is recommended to completely stop further use of the drug, and also be sure to consult a doctor!

In this article, we found out what Biseptol helps with, and also looked at how to take it correctly.

Biseptol for what diseases

At the end of the 20th century, Biseptol became such a common drug that it was used with or without a prescription for any reason, seeing it as a panacea for many ills. Today, the popularity of the medicine has begun to wane. Few people are interested in what biseptol is and what it helps with. However, this far from harmless remedy still remains in people’s minds as a cheap way to combat certain diseases. How justified is “unauthorized” treatment with Biseptol?

What is biseptol and is it related to antibiotics?

In the minds of Russian people, the most dangerous drugs in terms of side effects are antibiotics. In this regard, the question arises: is biseptol an antibiotic or not? Can I take it without a prescription?

The medicine belongs to the group of antiseptics, i.e. antibacterial drugs. The active ingredients in it are:

sulfamethoxazole (suppresses the reproduction and growth of bacteria); trimethoprim (increases the effect of sulfamethoxazole).

Biseptol cannot be classified as antibiotics, since the latter are substances natural origin, and the components of Biseptol are created in the laboratory.

Although the drug has nothing to do with antibiotics and belongs to the group of sulfonamides, you should not think that it is absolutely safe. With improper therapy, microorganisms become accustomed to the components of this product. Frequent use makes biseptol ineffective, and the disease enters the chronic stage.

The medicine is available in several forms:

in tablets of 480 and 120 mg (the latter option is for children); in the form of a suspension or syrup (1 teaspoon of suspension (5 ml) contains 240 mg of active substance; it must be shaken before use); in the form of ampoules of 480 mg for injection in a hospital setting.

When is Biseptol indicated?

The spectrum of influence of this representative of sulfonamides is quite wide:

In this regard, the range of diseases for which a doctor can prescribe Biseptol will also be wide:

respiratory diseases: tonsillitis, pharyngitis, tonsillitis, bronchitis, sinusitis, tracheitis and others; infectious diseases urinary tract; gastrointestinal diseases (typhoid fever, paratyphoid fever, diarrhea and others).

The desire of many people to use Biseptol to treat colds and acute respiratory viral infections is not always advisable, since these diseases are caused by viruses that are not sensitive to antibacterial drugs.

But for sore throat or bacterial complications after viral diseases of the ENT and respiratory organs, the use of the drug is completely justified. In these and other cases, the question arises of how to take Biseptol and what the dosages will be.

For children from 2 months to 5 years, a suspension is used - 240 mg 2 times a day. If the child can take tablets, then 2 tablets 2 times a day with a dosage of 120 mg are recommended.

Children over 6 years old can be given tablets with a dosage of 480 mg 2 times a day. For adolescents over 12 years of age and adults, the recommended dose is 960 mg 2 times a day. Treatment should last for at least 5 days and no more than 2 weeks. If you complete therapy before the time specified by the doctor, there is a risk of the most resistant microorganisms surviving and the disease becoming chronic.

It is quite natural to prescribe biseptol for cystitis. Most cases of this disease are caused by E. coli. However, you should not try any painful sensations in the area of the genitourinary system can be cured with this medicine. Most often, fluoroquinolone drugs are prescribed for cystitis. Unjustified use of Biseptol for cystitis can lead to the survival of some microorganisms, as a result of which the disease becomes chronic.

Biseptol should only be given to children under the supervision of a doctor. Most parents do not even have a clear idea of what Biseptol is and what it helps with. If you treat babies with it uncontrollably, you can only do harm. Most early age when you can give biseptol to children - from 6 weeks.

When taking medication, you must remember the following rules:

The medicine must be taken strictly every 12 hours; take the drug after meals; maintain the minimum course of treatment - 5 days.

Contraindications

Biseptol is not prescribed to patients:

with liver and kidney diseases; disorders of the hematopoietic system; during pregnancy and lactation; with individual intolerance to the components of the drug.

Side effects

Among the side effects of Biseptol are:

rash, hives, dermatological diseases; diarrhea, nausea, stomatitis, loss of appetite; intestinal dysbiosis; candidiasis, thrush.

These side effects are common. If they occur, you must immediately stop taking the drug.

In recent studies, other adverse reactions have been noted, but they occur once in several thousand people, for example, disruption of the hematopoietic system.

Most often in pharmacies you can find biseptol produced by Polish pharmacists. However, there are also less expensive foreign and Russian analogues:

Senexy Bactrim (France); Co-trimoxazole (Russia); Bi-septin (Holland); Septrin (England).

Which biseptol analogues to choose depends on the doctor’s recommendations and the patient’s financial capabilities. Dutch products are characterized by excellent quality, however Russian drug much cheaper.

Biseptol is by no means a harmless remedy, and you should not use it without consulting a doctor, even though it is not an antibiotic. Negligent treatment can lead to the fact that the medicine does not help, but only harms. You need to be especially careful with children: the side effects of Biseptol and incorrectly selected therapy sometimes provoke consequences that are difficult to correct.

What does Biseptol help with and what is its mechanism of action?

Biseptol actively affects the following microorganisms:

gram-positive and gram-negative bacteria;
protozoa;
staphylococci;
toxoplasma;
streptococci;
mushrooms;
coli.

Indications for use

Some patients believe that since Biseptol is not an antibiotic, it can be taken uncontrolled, but this is not so. The drug has serious side effects, and an increased dose of the drug will not cure prostatitis faster. It is necessary to follow the treatment regimen for prostate inflammation and follow all doctor’s recommendations.

Before starting to take the drug, it is necessary to exclude contraindications. Biseptol is not used in the following cases:

pregnancy and lactation;
childhood hyperbilirubinemia;
at risk of developing hemolysis.

Taking the drug may be accompanied by the following side effects:

urticaria, rash, erythema;
myalgia, arthralgia.

The tablet form is available in two dosages:
- 120 mg - for children;
- 480 mg - for adults.
Suspension for children with strawberry scent in a bottle of 80 ml. 1 dose - 5 ml contains 240 mg of active substances.
Concentrate for preparing a solution for infusion. 1 ampoule contains 480 mg of active substances.

Treatment in adolescents and adults:

Treatment in children

How to drink Biseptol in suspension?

The minimum dosage is calculated as follows:

How do Erespal and Biseptol combine when taken?

What does Biseptol help with: composition and release form

Today, the drug Biseptol is known in medicine as an effective antibacterial agent. For little money you can buy it at absolutely any pharmacy, also in some cases the drug can be taken without prior consultation with a doctor.

In addition, the medicine is actively used to treat prostatitis in men in combination with other drugs. Let's take a closer look at what Biseptol helps with.

The drug contains two main components - sulfamethoxazole and trimethoprim.

The suspension contains additional components such as sodium salt, citric acid, water, propylene glycol. The syrup is intended for children as it tastes sweet.

Ampoules are used to treat patients only in a hospital; they also contain additional substances: sodium, alcohol, ethanol, water.

The tablets are round in shape and light yellow in color. In addition to the main substance, they also contain starch, talc, and polyvinyl alcohol.

Release form

Biseptol is produced in different dosage forms:

Tablets (120 mg, 480 mg) packed in 20 pieces, each blister contains 10 tablets, so there are 2 blisters in a cardboard package.
Suspension for internal use(80 ml) is in a brown transparent bottle.
Ampoules for injection (8 ml).

pharmachologic effect

Biseptol is always prescribed in combination with other antibacterial agents. The main active ingredients contained in the drug actively destroy bacteria. Biseptol differs from other drugs in that it is capable of destroying bacteria that are not killed by drugs belonging to the sulfonamide class. The substances contained in the medicine disrupt the metabolism of pathogenic bacteria in the body and also destroy the synthesis of folic acid, as a result of which the microorganisms die. To understand what Biseptol helps with, you need to read the attached instructions.

Pharmacodynamics and pharmacokinetics

The components of the drug are quickly distributed throughout the body, entering the kidneys, lungs, prostate gland, and vaginal secretions. In addition, substances can cross the placenta to the fetus and enter the mother's breast milk. A large concentration in the body is observed already one hour after administration. Biseptol is excreted in the urine ten hours after administration.

How to take Biseptol: indications and contraindications

Biseptol is taken when patients have various diseases caused by bacteria. It should be remembered that the drug is considered a second-line antibiotic and does not affect many harmful microorganisms, is prescribed when pathogenic bacteria are resistant to first-line antibiotics.

The drug actively fights inflammation of the nasal mucosa, namely rhinitis, pharyngitis, laryngitis. In this case, the drug can be prescribed without additional powerful drugs.

To cure a specific disease, you need to know how to take Biseptol.

The medicine helps relieve inflammation of the prostate gland in men, alleviate the course of prostatitis, and also destroys bacteria that appear in uterine appendages in women, removes infections from the kidneys, bladder, urethra.

Biseptol acts on bacteria that have settled in the digestive organs, helping to cope with gastritis, pancreatitis, and enterocolitis. The antibiotic relieves inflammation formed in the liver, bile with a purulent process.

Biseptolom in tablet form is taken for acute infections that occur in the digestive tract.

Contraindications

Despite the fact that Biseptol is considered not strong antibiotic, it still cannot be used for certain diseases:

In case of individual intolerance to the components included in the drug.
In case of parenchymal pathology of the liver, when inhibition of the cells of this organ occurs.
In acute renal failure, especially when it is not possible to monitor the condition of the kidneys in the hospital.
For anemia, which is associated with a lack of folic acid in the body.
For blood dysfunction and changes.
During pregnancy and lactation, the active components of the drug lead to the body beginning to suffer from a deficiency of folic acid, which is considered the main one during this period.

Before taking the drug, it is necessary to consult a specialist, since all contraindications must be determined before starting treatment.

Side effects

Taking Biseptol can cause the body to exhibit an undesirable reaction, namely:

The digestive system will suffer, namely vomiting, diarrhea, nausea, inflammation of the liver, intestines, such a reaction may occur due to the fact that a deficiency of folic acid forms in the body.
Work will be disrupted circulatory system, anemia and leukopenia may occur. In addition, the number of platelets in the blood plasma may decrease, leading to thrombocytopenia.
There will be a malfunction in the urinary system, the kidneys and bladder will become inflamed, and a small amount of blood may appear in the urine.
A headache will occur, the person will become depressed, the mood will become depressed, this may be accompanied by frequent dizziness and vascular spasms.
An allergy will appear, which manifests itself in the form of a red rash on the skin, while the skin may experience itching and burning, urticaria, and Quincke's edema. In rare cases, patients experienced anaphylactic shock from the use of the drug, which occurred as a result of a gradual decrease in blood pressure.

Such side effects stop immediately after the patient stops taking Biseptol.

Overdose

If you exceed the prescribed dose of the drug, poisoning may occur in the form of nausea, vomiting, dizziness, abdominal pain, diarrhea, and confusion. If these symptoms occur, you should immediately stop taking the medication and call a doctor.

Before medical care you need to rinse your stomach and start symptomatic treatment. If a person exceeds the normal dose by three times or more, a chronic overdose may occur, which leads to inhibition of blood cells.

To avoid an overdose, you need to know how to take Biseptol and strictly follow the instructions.

Interaction

Biseptol should not be taken simultaneously with medications belonging to the class of diuretics, most often thiazides, otherwise thrombocytopenia may occur.

If Biseptol is taken simultaneously with Phenytoin, a person may experience folic acid deficiency.

Salicylic acid, contained in many drugs, can enhance the effect of this antibiotic.

The simultaneous use of ascorbic acid and those drugs that oxidize the urine can lead to crystalluria.

In case of simultaneous use of tetracyclic antidepressants, Biseptol reduces their effect.

The drug inhibits the microflora in the vagina and intestines, and can also lead to rupture of contraceptives. If a person takes this drug, he also needs to take probiotics.

Biseptol: dosage and instructions for use

Biseptol for prostatitis is taken according to a separate regimen. If the patient is diagnosed with a mild form of the disease, then the course does not exceed 21 days.

In the first few days, the doctor prescribes the maximum allowable dose of the drug, 6 tablets in two doses.

The first three tablets are taken in the morning, the last three at night. This dosage is considered the most correct for the acute course of the disease. The patient's condition improves already on the third day after the start of treatment.

Having completed one course, a man must take a break for a month, after which tests are taken again and if the result is unsatisfactory, the course is resumed.

Before taking Biseptol, the dosage must be agreed with a specialist.

In this case, the drug acts gently but effectively. The medicine does not reduce itself inflammatory process, kills pathogenic microorganisms, as a result of their death, inflammation goes away on its own.

The medication solution is injected into a vein. In this form, the drug is prescribed to children from 12 years of age, with a single dose not exceeding 10 ml. The drug is injected into a vein every 12 hours.

Biseptol tablets are taken twice a day every 12 hours. Adults are prescribed the drug 950 mg twice a day.

The suspension is taken by adults at a dosage of 950 mg per day. In severe cases of the disease, the dosage is increased to 1430 mg.

Pneumonia is treated with the drug Biseptol, the dosage of which is calculated depending on the patient’s body weight, 100 g. per 1 kg of weight.

If an infection is detected in the urine, you need to take 2 grams. medications twice a day. The course is set separately for each patient, most often it does not exceed two weeks.

If a child is diagnosed with urinary tract inflammation or acute otitis media, then 45 mg of medication per 1 kg of weight is prescribed. The drug is taken every 12 hours. Children under 12 years of age are prescribed a suspension 2 times a day; it has a sweetish taste and is easier for the child to accept. The usual dosage ranges from 2.5 ml for babies aged 4-6 months and up to 10 ml for children 12 years old.

During pregnancy and lactation

The drug should not be taken if the woman is pregnant and is breastfeeding her baby.

Terms of sale

You can buy the medicine in pharmacies, but a prescription from a doctor is required.

Storage conditions

The drug is stored at 25 degrees.

Best before date

Biseptol can be stored for no more than 5 years.

special instructions

While taking this drug, it is necessary to remember that the active substances reduce the strength of contraceptives; in addition, the antibiotic disrupts the microflora in the vagina and intestines. Treatment should take place at simultaneous administration probiotics.

Groseptol;
Berlocid;
Bactrim.

“It’s not a bad drug, but it helps only when the disease is not severe, mainly on initial stage, V difficult situations a stronger antibiotic is needed.”

“Biseptol cured my prostatitis in two doses, although the course was long, and I didn’t take anything else.”

Price, where to buy

Biseptol in all forms of release can be purchased in pharmacies.

The average cost of the drug in Russia is:

tablets from 50 to 150 rubles;
ampoules from 140 to 200 rubles;
suspension from 170 to 220 rubles.

Biseptol is a mild antibiotic, so it cannot be used for every disease. The active components of the medicine destroy bacteria, as a result the inflammation gradually goes away. As a rule, this drug is prescribed in combination with other drugs to achieve the best therapeutic effect. A single dose of medication is allowed in case of minor inflammation.

What does Biseptol help with and how to take it?

What is biseptol and is it related to antibiotics?

The medicine belongs to the group of antiseptics, i.e. antibacterial drugs. The active ingredients in it are:

sulfamethoxazole (suppresses the reproduction and growth of bacteria);
trimethoprim (increases the effect of sulfamethoxazole).

Biseptol cannot be classified as an antibiotic, since the latter are substances of natural origin, and the components of Biseptol were created in the laboratory.

Although the drug has nothing to do with antibiotics and belongs to the group of sulfonamides, you should not think that it is absolutely safe. With improper therapy, microorganisms become accustomed to the components of this product. Frequent use makes Biseptol ineffective, and the disease enters the chronic stage.

The medicine is available in several forms:

in tablets of 480 and 120 mg (the latter option is for children);
in the form of a suspension or syrup (1 teaspoon of suspension (5 ml) contains 240 mg of active substance; it must be shaken before use);
in the form of ampoules of 480 mg for injection in a hospital setting.

When is Biseptol indicated?

The spectrum of influence of this representative of sulfonamides is quite wide:

gram-positive and gram-negative bacteria;
toxoplasma;
streptococci and staphylococci;
protozoan microorganisms;
toxoplasma;
coli;
pathogenic fungi.

In this regard, the range of diseases for which a doctor can prescribe Biseptol will also be wide:

respiratory diseases: tonsillitis, pharyngitis, tonsillitis, bronchitis, sinusitis, tracheitis and others;
infectious diseases of the urinary tract;
gastrointestinal diseases (typhoid fever, paratyphoid fever, diarrhea and others).

For children from 2 months to 5 years, a suspension is used - 240 mg 2 times a day. If the child can take tablets, then 2 tablets 2 times a day with a dosage of 120 mg are recommended.

It is quite natural to prescribe biseptol for cystitis. Most cases of this disease are caused by E. coli. However, you should not try to cure any pain in the genitourinary system with this medicine. Most often, fluoroquinolone drugs are prescribed for cystitis. Unjustified use of Biseptol for cystitis can lead to the survival of some microorganisms, as a result of which the disease becomes chronic.

Biseptol should only be given to children under the supervision of a doctor. Most parents do not even have a clear idea of what Biseptol is and what it helps with. If you treat babies with it uncontrollably, you can only do harm. The earliest age when children can be given biseptol is from 6 weeks.

When taking medication, you must remember the following rules:

The medicine must be taken strictly every 12 hours;
take the drug after meals;
maintain the minimum course of treatment - 5 days.

Contraindications

Biseptol is not prescribed to patients:

with liver and kidney diseases;
disorders of the hematopoietic system;
during pregnancy and lactation;
with individual intolerance to the components of the drug.

Side effects

Among the side effects of Biseptol are:

rash, urticaria, dermatological diseases;
diarrhea, nausea, stomatitis, loss of appetite;
intestinal dysbiosis;
candidiasis, thrush.

These side effects are common. If they occur, you must immediately stop taking the drug.

In recent studies, other adverse reactions have been noted, but they occur once in several thousand people, for example, disruption of the hematopoietic system.

Most often in pharmacies you can find biseptol produced by Polish pharmacists. However, there are also less expensive foreign and Russian analogues:

Senexy Bactrim (France);
Co-trimoxazole (Russia);
Bi-septin (Holland);
Septrin (England).

Biseptol: instructions for use

The drug Biseptol is a combined antibacterial drug that has a wide spectrum of action and activity against a large number of different pathogenic bacteria infectious diseases. Due to the wide spectrum of action, Biseptol tablets are used for infectious pathology different locations in the body.

Release form and composition

Biseptol tablets are round in shape and White color. There is a dividing line in the middle of the tablet for easy breaking in half if it is necessary to reduce the dosage. In one tablet, the concentration of the active substance co-trimoxazole is 120 mg (sulfamethoxazole - 100 mg and trimethoprim - 20 mg) and 480 mg (sulfamethoxazole - 400 mg and trimethoprim - 80 mg). It also contains excipients, which include:

The tablets are packaged in blister packs of 20 pieces. One cardboard box contains one blister pack of tablets and instructions for use.

pharmachologic effect

The active ingredient of the tablets is co-trimoxazole. It is a combination of 2 compounds - sulfamethoxazole and trimethoprim. These substances have antimicrobial effect due to inhibition of the process of folic acid synthesis in the bacterial cell. Sulfamethoxazole blocks the formation of dihydrofolic acid, and trimethoprim blocks its subsequent conversion to tetrafolic acid. Folic acid is necessary for the normal course of the exchange of nucleotide bases in the bacterial cell, which are part of the genetic material (DNA and RNA). Thanks to this mechanism, Biseptol tablets in low concentrations have a bacteriostatic effect (inhibit the growth and reproduction of bacteria), and when the concentration increases, they have a bactericidal effect (cause the death of bacterial cells). Co-trimoxazole has activity against wide range different types of bacteria:

Gram-negative rods (rod-shaped bacteria that stain with Gram stain) pink color) - Enterobacter cloacae, Enterobacter aerogenes, Haemophilus parainfluenzae, Citrobacter freundii, Citrobacter spp., Klebsiella oxytoca, Klebsiella spp., Yersinia enterocolitica, Yersinia spp., Vibrio cholerae. Also Hafnia alvei, Serratia marcescens, Serratia liquefaciens, Serratia spp., cinetobacter lwoffi, Acinetobacter anitratus, Aeromonas hydrophila.
Gram-positive cocci (spherical bacteria, have a purple color in a Gram-stained smear) - Staphylococcus aureus (methicillin-sensitive and methicillin-resistant), Staphylococcus spp. (coagulase-negative), Streptococcus pneumoniae (penicillin-sensitive and penicillin-resistant).

The causative agents of specific infectious diseases (tuberculosis, syphilis) - Mycoplasma spp., Mycobacterium tuberculosis, Pseudomonas aeruginosa and Treponema pallidum - are resistant to the active substance of the drug.

After taking the tablets orally, the active substance is absorbed into the blood from the lumen small intestine. The therapeutic concentration in the blood is achieved minutes after taking the tablet, and the active substance is almost completely absorbed from the intestine (bioavailability above 90%). Co-trimoxazole penetrates well into all tissues of the body from the blood, penetrates the blood-brain barrier, and accumulates in brain tissue. In lower concentrations, it accumulates in the fetus during pregnancy (passes through the placental barrier) and breast milk during lactation. Almost half of the active substance is excreted unchanged in the urine by the kidneys. Co-trimoxazole is partially processed in the liver to intermediate breakdown products, which are excreted in the urine and bile.

Indications for use

The use of Biseptol tablets is indicated for various infectious processes in the body caused by bacteria sensitive to co-trimoxazole, these include:

Upper respiratory tract infections - rhinitis (inflammation of the nasal mucosa), pharyngitis (bacterial process in the pharynx), laryngitis (inflammation of the larynx).
Lower respiratory tract infections - tracheitis (inflammation of the trachea), bronchitis (damage to the bronchi), pneumonia (inflammation of the lungs, including those caused by Pneumocystis carinii pneumocystis).
Pathology of the ENT organs - sinusitis (inflammation of the mucous membrane of the paranasal sinuses), tonsillitis (infection of the tonsils) and otitis (inflammation of the outer, middle or inner ear).
Infections of the genitourinary system - prostatitis (inflammation of the prostate gland in men), a pathological infectious process in the uterine appendages in women, damage to the kidneys, bladder, ureters and urethra.
Infections of the digestive system and gastrointestinal tract– enterocolitis (inflammation of the small and large intestines), gastritis (bacterial infection of the stomach), pancreatitis (inflammation of the pancreas), infectious and purulent processes in the liver and biliary tract. Biseptol tablets are also used to treat especially dangerous infections with damage to the digestive system, in particular cholera.
Some generalized specific bacterial infections caused by co-trimoxazole-sensitive bacteria are brucellosis, actinomycosis (if it is not caused by true actinomycete fungi).

Biseptol is usually a second-line antibiotic; its use is advisable if bacteria are resistant to first-line antibiotics. Biseptol tablets can also be used to treat osteomyelitis (a purulent process in the bones) if sensitivity to co-trimoxazole is confirmed in pathogenic bacteria.

Contraindications for use

Biseptol tablets are contraindicated for use in a number of pathological and physiological conditions of the body, which include:

Individual intolerance or hypersensitivity to co-trimoxazole or excipients of the drug.
Parenchymal pathology of the liver with severe damage or death of hepatocytes (liver cells).
Renal failure, especially in cases where it is not possible to carry out laboratory monitoring of the functional state of the kidneys and the level of co-trimoxazole in the blood.
Anemia (anemia) associated with insufficient folic acid in the body.
Disturbances in the functional state of the blood system, accompanied by changes in hematological parameters.
Previous immunological decrease in platelet count caused by co-trimoxazole use.
Pregnancy at any stage of pregnancy and breastfeeding - co-trimoxazole can lead to a deficiency of folic acid, which is necessary for the normal development of the fetus or infant.

The presence of possible contraindications is determined before starting to use Biseptol tablets.

Directions for use and doses

Biseptol tablets are taken orally after meals and washed down with a sufficient amount of liquid. They are taken every 12 hours (2 times a day). The recommended therapeutic dose differs for people of different ages:

Children aged 2 to 6 years – 240 mg 2 times a day.
Children aged 6 to 12 years – 480 mg 2 times a day.
Children over 12 years of age and adults – 960 mg 2 times a day.

Also, the dosage of the drug differs, depending on the type of pathogen and severity infectious process in organism:

For pneumonia, the administered dose is calculated based on 100 mg per 1 kg of body weight.
For gonorrhea (infection of the urinary and reproductive system caused by gonococcus) - 2 g of the drug 2 times a day.

The duration of the course of use of the drug is prescribed by the doctor individually. Usually it is 5-14 days.

Side effects

Taking Biseptol tablets can lead to the development of negative reactions and side effects from various organs and systems, which include:

Digestive system - nausea, vomiting, loose stools, stagnation of bile in the biliary tract with the development of cholestatic hepatitis (liver inflammation), pseudomembranous colitis (specific intestinal inflammation caused by folic acid deficiency).
Hematopoietic system and blood - anemia (decrease in the level of hemoglobin and red blood cells), leukopenia (decrease in the number of leukocytes in the blood) with neutropenia (decrease in neutrophils). An autoimmune decrease in the number of platelets in the blood (thrombocytopenia) is also possible.
Urinary system - hematuria (the appearance of blood in the urine), nephritis (specific inflammation of the kidneys).
Central nervous system – headache, depression (decreased mood, depression), periodic dizziness.
Allergic reactions - a skin rash, itching, urticaria (characteristic swelling and rash that looks like a nettle burn), angioedema angioedema (severe swelling of the skin and subcutaneous tissue with a predominant localization in the face and external genitalia) may develop. Heavy allergic reaction characterized by the development of anaphylactic shock (multiple organ failure with a progressive decrease in systemic blood pressure).

If signs and symptoms of side effects appear, you should stop taking the drug and seek medical help. Side effects are reversible and disappear after discontinuation of the drug.

special instructions

Biseptol tablets can be used only after a doctor’s prescription, a study and an appropriate diagnosis. Regarding their use, there are several special instructions that you should pay attention to:

The drug is used with caution in patients with bronchial asthma, other types of allergies (provided that they did not develop to the components of the drug), acute or chronic liver or kidney failure, and the elderly.
The simultaneous use of Biseptol tablets with thiazide diuretics (diuretics) increases the risk of developing hypokalemia (decreased levels of potassium ions in the blood) and bleeding.
It is not advisable to simultaneously use Biseptol with salicylates, rifampicin, cyclosporine, warfarin.
You cannot combine Biseptol tablets and alcohol, as there is a high risk of developing toxic hepatitis.
When using the drug, it is necessary to ensure that a sufficient amount of fluid enters the body.
With prolonged use of Biseptol tablets, it is necessary to carry out laboratory monitoring of the functional state of the liver, kidneys and hematological blood parameters.
The drug is contraindicated for use by pregnant and lactating women.
The tablets do not have a direct effect on the speed of psychomotor reactions and concentration. However, when using them there is a risk of developing side effects from the central nervous system, so it is advisable to refrain from administering them while taking them. vehicles or mechanisms.

Biseptol tablets are available in pharmacies with a doctor's prescription. You cannot use the drug yourself or on the recommendations of third parties who are not specialists. If you have any questions or doubts about taking the drug, you should consult your doctor.

Overdose

When the recommended therapeutic dose is significantly exceeded, symptoms develop acute poisoning– nausea, vomiting, abdominal pain, headache, disturbances of consciousness. In this case, you should stop taking the drug and seek medical help. Detoxification therapy includes gastric lavage, intestinal lavage and symptomatic therapy. Chronic overdose can lead to suppression of hematopoiesis with a significant decrease in the number of all blood cells.

Analogs of Biseptol tablets

The active ingredient co-trimoxazole is included in such drugs that are analogues of Biseptol - Groseptol, Berlocid, Bactrim, Co-trimoxazole.

Terms and conditions of storage

The shelf life of Biseptol tablets from the date of their manufacture is 5 years. The drug must be stored in a dry, inaccessible place with an air temperature no higher than +25° C.

Biseptol price

Biseptol tablets 120 mg - from 27 to 37 rubles.

Biseptol tablets 480 mg - from 83 to 109 rubles.

Biseptol is a drug that has an effective bactericidal effect. It is used in the treatment of a wide range of diseases and only as prescribed by the attending physician. The drug is not an antibiotic, but belongs to the class of sulfonamides. Biseptol consists of active components that complement therapeutic effect each other: trimethoprim and sulfamethoxazole.

pharmachologic effect

Biseptol contains 2 main ingredients: active substances- sulfamethoxazole and trimethoprim, which have an effective bactericidal and bacteriostatic effect.

Sulfamethoxazole interferes with the release of dihydrofolic acid in bacterial cells. Trimethoprim, in turn, prevents the development of dihydrofolic acid into the active form of folic acid, which affects protein metabolism and microbial cell division.

Biseptol is absorbed fairly quickly. Its duration of action is 7 hours. The largest number of Biseptol components is concentrated in the lungs and kidneys. The drug is excreted from the body along with urine within 24 hours after administration.

Biseptol does not help in the treatment of runny nose, cough, colds and flu; more precisely, its use is inappropriate, since in most cases these diseases are caused by viruses that are resistant to antibacterial drugs. But the use of Biseptol for sore throat or complications of diseases of the ENT organs that are bacterial in nature is quite justified.

The instructions for use of Biseptol indicate infectious inflammatory pathologies organisms provoked by pathogenic organisms sensitive to medicine. Biseptol helps with the following conditions.

Infectious diseases of the respiratory system:

pneumonia;
acute and chronic bronchitis;
lung abscess;
pleural empyema;
bronchiectasis.

Diseases of the upper respiratory tract and throat diseases developed against the background of respiratory infections:

Infectious and inflammatory diseases of the genitourinary system:

Infectious diseases of the gastrointestinal tract:

Infectious diseases of soft tissues and skin:

Infectious diseases carried by animals and insects:

Severe forms of infectious and inflammatory diseases:

meningitis;
brain abscess;
osteomyelitis;
sepsis;
wound infections.

Biseptol is prescribed to children in cases of contraindications to antibiotics. Its most effective use is in the treatment of:

tonsillitis;
sinusitis;
respiratory infections (including pneumonia and bronchi);
inflammation of the middle ear;
intestinal infections;
infectious lesions of soft tissues;
furunculosis.

Release form

Biseptol is available in different forms:

Tablets of 120 milligrams for children.

Packed in blisters of 20 pieces. Contents of 1 tablet: 100 milligrams of sulfamethoxazole, 20 milligrams of trimethoprim and excipients: polyvinyl alcohol, propylene glycol, potato starch, magnesium stearate, aseptin P and M, talc.

480 milligram tablets for adults.

Packed in a blister of 20 pieces. Contents of 1 tablet: 400 milligrams of sulfamethoxazole, 80 milligrams of trimethoprim, and similar excipients.

Suspension nursery for oral administration light cream color with strawberry scent.

5 milliliters (teaspoon) of Biseptol suspension contains 200 milligrams of sulfamethoxazole, 40 milligrams of trimethoprim, propylene glycol, maltitol, propylhydroxybenzoate, citric acid, sodium saccharinate, methylhydroxybenzoate, sodium salt, Cremophor RH 40, sodium hydrogen phosphate, magnesium-aluminum silicate, purified water and strawberry flavoring. The drug is packaged in 80 ml dark glass bottles.

Concentrate in ampoules 5 milliliters each for preparing a solution for infusions (droppers).

1 milliliter of Biseptol contains 80 milligrams of sulfamethoxazole and 16 milligrams of trimethoprim. The drug contains 10 ampoules and is packed in a cardboard box.

The course of treatment and dosage of Biseptol is selected individually by the attending physician, depending on the general condition health, age and concomitant diseases of the patient. In case of severe illnesses, the doctor has the right to double the dosage of Biseptol.

Children from 6 months to 5 years are usually prescribed a syrup or suspension. The recommended dose is 5 milliliters of suspension 2 times a day.

Children who are able to swallow a tablet should take 2 tablets (120 milligrams) twice daily.

Children from 6 years of age are prescribed Biseptol tablets 480 milligrams twice a day.

For patients over 12 years of age, Biseptol is prescribed at a dosage of 960 milligrams twice a day.

For pneumonia

Biseptol is prescribed at the rate of 100 milligrams of sulfamethoxazole per kilogram of body weight per day. The interval between doses should be 6 hours, and the course of treatment should be 2 weeks.

For gonorrhea

The drug is taken 2 grams (in terms of sulfamethoxazole) twice a day with an interval of 12 hours.

For cystitis

If the disease is caused by E. coli, then before using Biseptol, you need to take a sensitivity test to the drug. The drug is prescribed in a dosage of 2 tablets 2 times a day, for a course of 5 to 10 days.

For sore throat

Biseptol is prescribed as recommended age dosage for 5-10 days. Although recently, Biseptol has been prescribed less and less frequently for angina, since studies show that the causative agents of the disease (streptococci and staphylococci) lose sensitivity to this drug.

Admission rules

A 12-hour interval should be strictly observed between doses of the drug.
Biseptol should be taken only after meals, as the medicine irritates the walls of the stomach.
The course of therapy must be at least 5 days, otherwise a complication may develop.
During treatment, it is important to exclude from the diet protein food, it reduces the effectiveness of the drug and complicates its absorption. And also refuse alcoholic drinks.

Failure to comply with these rules may lead to a decrease in the effectiveness of Biseptol or side effects.

Contraindications

Damaged liver parenchyma and severe liver failure;
Renal dysfunction and renal failure;
Hematopoietic disorders and severe blood diseases (agranulocytosis, aplastic anemia, leukopenia, megaloblastic anemia, B12-deficiency anemia);
Pregnancy and lactation;
Age up to 3 months;
Hyperbilirubinemia;
Jaundice in children;
Lack of glucose-6-phosphate dehydrogenase;
Hypersensitivity to the composition of the drug.

Biseptol is prescribed with extreme caution for:

diseases of the thyroid gland;
bronchial asthma;
hay fever;
atopic dermatitis;
lack of folic acid in the body.

Side effects

According to studies, in most cases Biseptol is well tolerated. However, after long-term use of the drug, there is a possible risk of developing candidiasis and thrush. On the background accompanying pathologies and the body's sensitivity to the drug, the following side effects may occur.

Nervous system disorders:

apathy;
depression;
aseptic meningitis (caused by bacteria);
severe and prolonged headaches;
dizziness;
tremor (involuntary contractions of the muscles of the trunk or limbs);
peripheral nerve inflammation.

Gastrointestinal tract dysfunctions:

diarrhea, abdominal pain;

nausea, vomiting;

pseudomembranous enterocolitis;

gastritis;

pancreatitis;

glossitis (inflammation of the tongue);

hepatitis.

Respiratory system disorders:

inflammatory allergic reaction of lung tissue;
cough;
bronchospasms.

Disturbances in the functioning of the circulatory system and complications in hematopoiesis:

thrombocytopenia (reduced number of platelets in the blood);
neutropenia (reduction or absence of granulocytes in the blood);
leukopenia (decreased white blood cells);
megaloblastic anemia.

Problems of the urinary system:

polyuria ( advanced education amount of urine);
hematuria (the appearance of blood in the urine);
increased urea concentration;
crystalluria (presence of salts in urine);
kidney dysfunction.

Painful manifestations from the musculoskeletal system:

muscle pain;
joint pain.

Manifestation of allergic reactions:

Do not be afraid of an overly impressive list of adverse reactions to Biseptol. They have been noted throughout the production and use of the drug, but can only occur in one in several thousand people.

Pathogenic bacteria are present in the surrounding space of a person, and therefore in his body. Immune cells do not allow pathogenic microflora to develop, but when immunity is weakened or other factors occur, microbes begin to actively multiply in the body, causing various diseases.

Among pathogens- bacteria, viruses, fungi. Since these are different biological objects, treatment should be prescribed in accordance with the pathogen. The doctor prescribes a medicine that will be effective in the fight against a particular microbe. One of the most frequently prescribed drugs against bacteria is Biseptol. What Biseptol helps with and how to take it, we’ll look at it in the article.

For the treatment of various inflammatory diseases, two types of drugs are prescribed: antibacterial and antimicrobial. The former contain substances that kill bacterial cells, while the latter inhibit protein synthesis in the enemy cell and stop its vital activity.

Active ingredients Biseptol does not have any components found naturally natural environment, and therefore the medicine does not belong to the group of antibiotics. In other words, the drug is completely synthetic.

Composition of the medicine:

sulfamethoxazole - the main active ingredient, stops the growth and development of bacteria;
trimetroprin - has an auxiliary effect, prevents the restoration and reproduction of pathogenic microflora.

Co-trimozole is synonymous with sulfonamides. It is part of Trimethoprim, an antibiotic that is widely used to treat diseases of the urinary system.

Pharmachologic effect:

The bacteriostatic property of the drug is achieved by blocking the biosynthesis of folic acid in bacterial cells by the active substances. Folic acid is involved in metabolic processes, in which, using nucleic acids microbial protein synthesis occurs. Violation of biochemical reactions in the cell leads to a stop in reproduction and to its death from the inside.

Biseptol actively affects the following microorganisms:

gram-positive and gram-negative bacteria;
protozoa;
staphylococci;
toxoplasma;
streptococci;
mushrooms;
coli.

Pathogenic microflora causing syphilis and tuberculosis are resistant to sulfonamides.

Indications for use

Biseptol is indicated for the treatment of diseases infectious nature caused by microorganisms sensitive to the active substances of the component. Asking the question: “What does Biseptol help with?” It should be understood that you cannot self-medicate. Only a doctor can correctly determine whether a drug will be effective or not after examining the patient.

The medicine helps with inflammatory diseases of the respiratory system: rhinitis, bronchitis, pharyngitis, pneumonia, laryngitis and others.
Bispetol is often prescribed for infectious lesion organs of the genitourinary system: prostatitis, inflammation of the uterine appendages, pathological processes in the kidneys, bladder, urethra.
The drug is effective for the treatment of the digestive system: inflammation of the pancreas (pancreatitis), inflammatory processes in the small and large intestines (enterocolitis), gastritis.
Biseptol is prescribed for pathologies of the ENT organs accompanied by infection: inflammation maxillary sinuses(sinusitis), inflammatory processes occurring in the inner and outer ear (otitis), purulent inflammation in the tonsils.

Therapeutic effect on prostatitis

Biseptol for prostatitis is one of the most powerful medications to combat the disease. It is prescribed if the pathology of the prostate gland is infectious. The active ingredients of the drug penetrate deep into the prostate tissue, stopping the development of pathogenic bacteria. Reducing the number and activity of bacteria reduces pain, swelling of the prostate, and eliminates other symptoms.

Prostatitis should be treated with Biseptol only on the recommendation of a doctor. Self-medication may be useless or even harmful. After the examination, the specialist will calculate the dosage that will be optimal.

You need to take the drug for inflammation in the prostate for at least two weeks. The first few days the doctor prescribes maximum dosage, which then decreases. The patient feels relief after 2-3 days, but it is important not to interrupt the course of treatment, since bacteria can develop resistance to the drug. This, in turn, can lead to a chronic form of prostatitis, which is difficult to treat.

Therapeutic effect on other pathologies

Biseptol is prescribed for many inflammatory diseases of the respiratory system and ENT organs. And sometimes people think that it can be taken for acute respiratory infections, but in this case the drug is useless, since these diseases are caused by viruses. But Biseptol treats tonsillitis, tonsillitis, sinusitis and other diseases complicated by bacterial microflora perfectly.

You should be careful when treating Biseptol when it comes to children. Even if in the past the doctor prescribed a drug to treat, for example, a sore throat, then recurrent illness Under no circumstances should you give your child medicine on your own.

Otherwise, the bacteria will become resistant, and sore throat will appear again and again.

The therapeutic effect of sulfonamides on different organs manifests itself in the same way, since the principle of action on bacterial cells is the same. But the doctor determines the dosage and course of treatment individually.

Before starting to take the drug, it is necessary to exclude contraindications. Biseptol is not used in the following cases:

When taking the drug, people suffering from bronchial asthma and pathologies in the thyroid gland should be careful.

The drug may have a negative effect on different systems body: nervous, respiratory, digestive, musculoskeletal, hematopoietic system.

Taking the drug may be accompanied by the following side effects:

dizziness and pain in the head;
depression, apathy and peripheral neuritis;
abdominal pain, nausea, diarrhea, vomiting;
urticaria, rash, erythema;
cough, suffocation, bronchospasm;
anemia, neutropenia, agranulocytosis, thrombocytopenia;
increased urea concentration, impaired renal function;
myalgia, arthralgia.

How to take Biseptol for children and adults

For ease of use, Biseptol is available in different dosage forms.

Tablet form Available in two dosages:
- 120 mg - for children;
- 480 mg - for adults.
Suspension for children with strawberry scent in a bottle of 80 ml. 1 dose - 5 ml contains 240 mg of active substances.
Concentrate for preparing the solution for the purpose of infusions. 1 ampoule contains 480 mg of active substances.

How to take Biseptol and in what dosage forms depends on the disease and age of the patient.

Treatment in adolescents and adults:

The minimum dose for treatment longer than 14 days is 480 mg every 12 hours. The standard dosage is 960 mg twice a day; for severe infections, the dose is increased to 1440 mg every 12 hours.

The course of treatment for respiratory tract and ENT infections is ten days.
Treatment of inflammatory diseases of the genitourinary system lasts from fourteen to twenty-one days.
Diseases of the gastrointestinal tract are treated for at least five days.
Treatment for infectious diseases of the genital organs (chancroid) lasts from seven to fourteen days.
For treatment acute infections urinary tract In women, “shock” therapy is carried out, in which a single dose is up to 2880 mg.
Pneumonia is treated with 960 mg twice a day. The individual dosage is calculated at 30 mg/kg.
Nocardiosis is treated at a dosage of 2880 mg for at least three months, acute brucellosis - four weeks, typhoid fever - three months.

How to drink Biseptol in tablets and suspension?

The tablets are taken every 12 hours, so the medication should be taken in the morning and evening. The drug should be taken only after meals, the tablet should be washed down with plenty of clean water.

Do not take the medicine on an empty stomach, otherwise it may cause side effects.

Treatment in children

Up to five years of age, the medicine is prescribed in a standard dosage of 240 mg in the morning and evening. From six to twelve years - 480 mg twice a day. The duration of treatment is seven days.

For children from two months to six months of age, born from a mother infected with HIV, the dosage is 120 mg.

For children, Biseptol is most often prescribed for the treatment of intestinal infections, sore throat, otitis media, laryngitis and other infectious diseases of the respiratory tract.

The syrup is used from two months of age, and 120 mg tablets from two years of age.

For individual dosage, the suspension is calculated based on 36 mg of the drug per 1 kg of weight.

How to drink Biseptol in suspension?

The child should be given the medicine after meals; it is advisable to maintain a 12-hour interval between taking the suspension. The medicine is taken with a special measuring syringe through the neck of the bottle. Before taking the suspension, shake the bottle well to agitate the liquid. There are special divisions on the syringe that determine the dosage.

Biseptol suspension has a pleasant berry taste, so children drink it easily. If the child wants to drink the medicine, you can give him clean water.

It is important to give the child the medicine exactly in the dose prescribed by the doctor; in no case should you be independent in this matter.

The minimum dosage is calculated as follows:

up to six months - 2.5 ml in the morning and evening;
up to three years of age - 2.5-5 ml twice a day;
up to the age of six - 5-10 ml every 12 hours;
up to twelve years - 10 ml every 12 hours.

Prices:

Tablets 120 mg 20 pieces - 30 rubles;
Tablets 480 mg 28 pieces - 90 rubles;
Suspension 240 mg / 80 ml - 120 rubles.

How do Erespal and Biseptol combine when taken?

Biseptol does not combine well with various drugs and alcohol. For inflammatory diseases of an infectious nature, it is prescribed first; if the medicine does not help, the doctor adjusts the treatment.

Erespal is prescribed for the treatment of infectious diseases of the upper respiratory tract. The drugs have different pharmachologic effect on the body, therefore, the question of combining the techniques of Erespal and Biseptol is best answered by the attending physician.

In contact with

In this article we will look at how to drink Biseptol.

One of the most famous and controversial antibacterial drugs sold in Russia is Biseptol. In the 80-90s of the last century it was at the peak of its popularity. The drug was prescribed by doctors of all specializations, from a local pediatrician to a highly specialized urologist. Patients, having felt the effectiveness of the product, perceived it as a panacea for all ills. If at first we did not risk buying Biseptol without a doctor’s prescription, then soon such a “trifle” as a specialist’s recommendation began to seem unnecessary. It was seen as salvation from any infection and was taken almost uncontrollably for any reason, not excluding a common cold.

It is a drug that has a bactericidal effect. It is used in the treatment of a wide range of pathologies and only as prescribed by a doctor. This drug is not an antibiotic; it belongs to the class of sulfonamides. The medicine "Biseptol" consists of active components that complement the therapeutic effects of each other, namely sulfamethoxazole and trimethoprim. How many days to drink Biseptol is indicated in the instructions.

Composition of the medicine

The composition includes two main active components: sulfamethoxazole and trimethoprim, they have an effective bacteriostatic and bactericidal effect. Sulfamethoxazole can interfere with the release of dihydrofolic acid in the bacterial cell. Trimethoprim, in turn, prevents the development of dihydrofolic acids into the active form of folic fluids, which affect protein metabolism, and, in addition, microbial cell division.

Many people are interested in how much Biseptol should be taken.

Pharmacological effects

The drug in question is quite active against Escherichia coli, streptococci, staphylococci, pneumococci, the causative agent of typhoid fever, dysentery and Proteus. But, however, this drug is absolutely powerless against tuberculosis and Pseudomonas aeruginosa, viruses and spirochetes. The drug "Biseptol" can be absorbed quite quickly. The duration of its effect is seven hours. The largest amount of Biseptol ingredients is concentrated in the kidneys and lungs. This drug leaves the body in the urine within twenty-four hours after administration.

Everyone should know how to drink Biseptol.

Indications for use

When treating runny nose, cough, flu and colds, Biseptol does not help patients; more precisely, its use in this case is inappropriate, since in most cases these diseases can be triggered by viruses that are resistant to antibacterial medications. But the use of “Biseptol” for sore throat or complications of diseases of the otolaryngological organs, which are bacterial in nature, is completely justified.

The instructions for use indicate how to drink Biseptol 480 mg, as well as infectious and inflammatory pathologies of the body that are provoked by pathogens and are sensitive to the drug. The medicine helps patients with the following conditions.

Release form

The drug "Biseptol" is produced in various forms:

In the form of pills of 120 milligrams. These tablets are intended for children. They are packaged in blisters of twenty pieces. One tablet contains 100 milligrams of sulfamethoxazole, and, in addition, 20 milligrams of trimethoprim along with excipients in the form of polyvinyl alcohol, propylene glycols, potato starch, magnesium stearate, aseptin and talc.
In the format of 480 milligram tablets intended for adults. Such pills are packaged in blisters of twenty pieces. One tablet contains 400 milligrams of sulfamethoxazole along with 80 milligrams of trimethoprim and similar excipients.
In the format of a children's suspension intended for oral use. This medicine has a light cream color with the smell of strawberries. 5 milliliters of the Biseptol suspension in question contains 200 milligrams of the sulfamethoxazole component along with 40 milligrams of trimethoprim, propylene glycols, maltitol, propyl hydroxybenzoate, citric acid, saccharinate, methylhydroxybenzoate, sodium salt, cremophor, sodium hydrogen phosphate, aluminum silicate, purified water and strawberry flavor. This drug is packaged in special dark glass bottles in a dosage of 80 milliliters.
In the format of a concentrate in ampoules of 5 milliliters, intended for the preparation of solutions for droppers. One milliliter of Biseptol contains 80 milligrams of sulfamethoxazole and trimethoprim. The drug is produced in the form of 10 ampoules, which are packed in a cardboard box.

Dosage

How to take Biseptol, in what dosage?

The course of therapy and dosage of the medication is selected by the attending physician individually, depending on the state of health, and, in addition, on the age and concomitant pathologies of the patient. In the presence of serious illnesses The doctor has the right to double the dosage.

Do you drink Biseptol before or after meals? The medicine is taken after meals.

For children and adults

Children aged from six months to five years are usually prescribed a syrup or suspension. The recommended dosage is 5 milliliters of suspension twice. Children who are able to swallow a tablet should take two tablets (that is, 120 milligrams) twice a day.

How much Biseptol can older children take?

Children from the age of six are prescribed tablets with a dosage of 480 milligrams twice a day.

For adults, the drug "Biseptol" is prescribed in a dosage of 960 milligrams twice.

How many days to take Biseptol for pneumonia? Let's look further.

If you have pneumonia

The drug "Biseptol" is prescribed at the rate of 100 milligrams of sulfamethoxazole per kilogram of weight per day. The interval between doses should be about six hours, and the course of therapy is required for two weeks.

How much to take Biseptol for gonorrhea? More on this below.

If you have gonorrhea

If a patient develops gonorrhea, this drug is taken 2 grams (in terms of sulfamethoxazole) twice with an interval of twelve hours. You should not prescribe the dosage and time of taking such a serious drug on your own, since there are many side effects.

If the patient has cystitis

How to take Biseptol for cystitis?

If the disease was caused by E. coli, then immediately before using the drug “Biseptol” you need to take sensitivity tests to this drug. The drug is prescribed in a dosage of two tablets twice a day, for a course of five to ten days.

It is better to find out in advance how to take Biseptol for cystitis.

If you have a sore throat

In this case, the drug “Biseptol” is prescribed in the recommended age dosage for five to ten days. True, recently, in the presence of a sore throat, Biseptol is prescribed less and less, since studies show that the causative agents of the disease (which are streptococci and staphylococci) simply lose sensitivity to the drug in question.

How much to drink Biseptol is now clear.

A twelve-hour interval must be strictly observed between doses of this medication.
It is necessary to take the medicine "Biseptol" only after meals, since the drug in question significantly irritates the walls of the stomach.
The course of treatment should be at least five days, otherwise complications may develop.
During the period of therapy, it is important to exclude protein foods from the diet, which reduce the effectiveness of this drug and complicate its absorption.

So, you can drink Biseptol when various pathologies, but you need to do it correctly.

It is also extremely important to give up all kinds of alcoholic beverages. Failure to comply with these basic rules can lead to a decrease in the effectiveness of treatment or the appearance of side effects.

Contraindications

This drug should not be taken in some of the following cases:

In the presence of damaged liver parenchyma and severe liver failure.
In case of impaired renal function and failure of this organ.
Against the background of hematopoietic disorders and severe blood diseases, in the presence of agranulocytosis, aplastic anemia, leukopenia and megaloblastic disease. Also, this remedy is completely unsuitable for use if a person has B12 deficiency anemia.
In case of pregnancy and lactation periods.
Up to three months of age.
Against the background of hyperbilirubinemia and jaundice in children.
If the patient has a deficiency of phosphate dehydrogenase.
Against the background of increased sensitivity to the composition of this drug.

With great caution, the drug "Biseptol" is prescribed for pathologies of the thyroid gland, against the background of bronchial asthma, hay fever, atopic dermatitis and a lack of folic acid in the body. Patients are strongly advised not to stay while taking this drug. for a long time in the open sun.

The development of possible adverse reactions depends on how many times Biseptol is taken.

Side effects

According to studies, in most situations the medicine called Biseptol is tolerated very well by patients. However, after long-term use of this drug, people may be at risk of developing candidiasis and thrush. Against the background of concomitant diseases and the sensitivity of the human body to the drug in question, various side effects may occur:

It is likely that the functioning of the nervous system is impaired, which can manifest itself in the form of apathy, depression, aseptic meningitis (which is caused by bacteria), severe and prolonged headaches, dizziness, tremors (that is, involuntary contraction of the muscles of the limbs or torso) and inflammation of the peripheral nerve.
Malfunctions in the functions of the digestive system are likely. In this case, we can talk about lack of appetite, diarrhea, abdominal pain, nausea, vomiting, pseudomembranous enterocolitis, gastritis, pancreatitis and glossitis (inflammation of the tongue). Hepatitis is also possible.
The respiratory organs can respond with an inflammatory allergic reaction of the lung tissue, cough and bronchial spasms.
Some disturbances in the functioning of the circulatory system are possible, along with complications in hematopoiesis, which can be expressed in thrombocytopenia (reduced number of platelets in the blood), neutropenia (decreased or absent granulocytes in the blood), leukopenia (decreased white blood cells) and megaloblastic anemia.
Problems with the urinary system may also occur in the form of polyuria (increased urine production), hematuria (blood in the urine), excessive concentration of urea, crystalluria (the presence of salts in the urine) and kidney dysfunction.
Additionally, some painful manifestations from the musculoskeletal system may be observed, with possible muscle pain along with discomfort in the joints.
The occurrence of allergic reactions in the form of urticaria, itching, rash, allergic myocarditis, fever, scleral hyperemia, angioedema, exfoliative dermatitis, toxic epidermal necrolysis, photosensitivity and exudative erythema multiforme cannot be excluded.

But it must immediately be emphasized that you should not be afraid of such an excessive and impressive list of all kinds of adverse reactions that may manifest themselves as a response to taking Biseptol. These have actually been observed throughout the production and use of the drug in question, but may only occur in one in several thousand patients.

Is the drug "Biseptol" an antibiotic?

Many patients are often concerned about this issue. Therefore, due to adverse reactions from antibiotics, patients agree to therapy with them only in extreme cases and want to do without them altogether.

Speaking in simple language, it is worth considering that antibiotics are aimed at suppressing and, in addition, destroying bacteria. In other words, such medications have an antibacterial effect. Antibiotics are distinguished by their natural (or sometimes semi-synthetic) origin. They are plant, microbial and animal.

If you study the instructions for Biseptol pills, you will see that both components of this medicine are synthesized in the laboratory. The main component is sulfamethoxazole, which is a sulfonamide ingredient. And the second substance, trimethoprim, was added to the drug in order to enhance the effect of the first. Thus, the conclusion is quite obvious: the drug “Biseptol” is not considered an antibiotic, despite the fact that it has an antibacterial effect on the human body. Considered medical drug acts as a sulfonamide agent.

You can take Biseptol tablets, however, you should not naively assume that since it is not an antibiotic, it is completely safe, just like, for example, biologically active additives with vitamins. There are, for example, side effects, of which, I must say, there are many. In addition, improper use and dosage can lead to the formation of bacteria that are resistant to the drug. Sulfonamides, along with antibiotics, serve as serious medications classified as prescription drugs. Among the analogues of "Biseptol" it is worth mentioning medical supplies in the form of "Groseptol", "Bactirm", "Septrin" and "Bifeseptol". How should an adult take Biseptol for a cold?

Common cold

Many patients refrain from antibiotic treatment and want to avoid them at all costs. But there is another category of patients who are convinced that antibiotic treatment will be unnecessary in the presence of a cold, otitis media, acute respiratory infections, and even a long-term runny nose. It is scary to note that even on children, their parents sometimes conduct similar experiments. In this regard, it is worth finding out how to drink Biseptol for a cold.

To do this, it is necessary to recall that some diseases are caused by viruses, while others are caused by bacteria. Many patients are simply not competent enough to distinguish and understand the causes, that is, to determine the causative agent of some kind of inflammation. Experienced therapists, in turn, will be able to do this without difficulty.

So, ARVI is called acute respiratory viral infections. Flu, by the way, is also caused by viruses. However, according to the instructions, it becomes obvious that the drug “Biseptol” does not destroy viruses at all. Therefore, if you have a cold and flu, with the hope of recovery, swallowing pills will not achieve any effect, and even some complications are possible.

Typically, influenza and otolaryngological diseases go away on their own after one week. But if a child’s or adult’s body is very weakened, then coccal infections are quite possible. Now the drug “Biseptol” can be useful for therapy.

How can one determine whether a bacterial infection has joined a viral one or whether something similar has not happened? Usually, when people have the flu, their temperature rises in the first days. Then the temperature disappears and the person thinks that he has begun to recover. But it is at this moment, after about a week, that an attack of fever may begin again. At the same time, it is most likely impossible to reduce the temperature for a long time, since it will rise again and again. If the first seven days a person just had a runny nose with a headache, then later coughing attacks begin. All this indicates that now the causative agents of painful health are pathogenic pathogenic bacteria. This means that the time has come for a person to take care of antibacterial therapy.

We looked at how to drink Biseptol.

Biseptol - are they antibiotics or not? The medicine is not classified as an antibiotic. It is assigned antimicrobial properties. The complex medicine Biseptol based on sulfamethoxazole and trimethoprim fights streptococci, pneumococci, salmonella, gonococci, chlamydia, and some groups of fungi. The description of the medication notes that the drug has no effect on viruses, Pseudomonas aeruginosa and the causative agent of tuberculosis.

The drug stops the production of folic acid, which is so necessary for the development and reproduction of microbes. The incoming components interact well with each other and enhance each other's effects.

The drug Biseptol is relatively quickly and almost completely absorbed from digestive tract, begins to act within a couple of hours after administration. The maximum effect in the body lasts for 6 hours. Remains of the drug are excreted by the kidneys along with urine.

To understand whether Biseptol is an antibiotic, you need to understand its effect on the body. The drug belongs to the synthetically derived group antimicrobial agents. Synthetics are not considered antibiotics. Biseptol exhibits its effect in the blood and purulent foci. They conduct treatment courses for infectious diseases when antibacterial medications are undesirable or contraindicated.

Biseptol has a varied and convenient release form for the individual case of treating the disease. It is produced in the form of tablets, suspension and solution for injection. You can choose a convenient dosage prescribed by your doctor.

Reviews about the drug from users are mostly positive. It is noted that improvement occurs after taking one dose. There are no problems with treating children. It has a sweet taste and a pleasant smell. Many patients note that “I drank Biseptol when chronic bronchitis and within a week the symptoms disappeared, and after two weeks I forgot about the disease.” Negative reviews associated with the development of side effects. The most common symptoms are nausea and vomiting.

Cases of assistance

In what cases should Biseptol be taken and what does it help with? Common indications for the use of Biseptol include:

pathological processes occurring in the bronchi and lungs, for example, bronchitis, pneumonia, lung abscess;
inflammatory diseases of the ENT organs, for example, sinusitis, otitis media, sinusitis;
Biseptol 480 quickly stops infections in the intestines (copes with dysentery, salmonellosis, cholera);
pathological processes occurring in the organs of the urinary and reproductive systems, for example, pyelonephritis, cystitis, prostatitis;

helps with gonorrhea;
purulent skin lesions, for example, furunculosis;
inflammatory processes in brain structures;
used for toxoplasmosis, malaria, scarlet fever.

Contraindications for Biseptol include serious illnesses heart and blood vessels, diseases of the hematopoietic organs, liver and renal failure. Should not be given to children under three months of age or to those who are born ahead of schedule.

Biseptol should not be taken during pregnancy or breastfeeding. As a result, problems with intrauterine development, premature birth, and even unauthorized termination of pregnancy are possible.

In the instructions for use of Biseptol 480, the paragraph on side effects that negatively affect the body’s condition notes the following points:

while taking it, you may experience nausea and even vomiting, loose stools, poor appetite, pain in various parts of the abdomen, hepatitis, pancreatitis;
Pain in the head, dizziness, apathy and irritability may appear;
sometimes there are attacks of suffocation, coughing, difficulty breathing;
on skin a rash may be noticeable;
the level of sodium, potassium and sugar in the blood may decrease;
pain in muscles and joints.

Treatment should be carried out under the supervision of a specialist and blood counts should be constantly checked. Side effects most often disappear at the end of the course. The reason to stop treatment is skin rash and diarrhea.

Symptoms of overdose are nausea, turning into vomiting, pain in the abdomen, head, dizziness, lack of appetite, loss of consciousness. In this case, immediately stop taking the drug and perform gastric lavage.

Important Rules

How to take Biseptol to get maximum results and avoid unpleasant reactions? Instructions for use of Biseptol indicate that it is recommended to take the medicine after drinking a glass of boiled water. You cannot take Biseptol tablets with milk, as the product reduces its effectiveness. You need to drink at least 2 liters of water per day. This will avoid the appearance side effects.

The instructions for use of the medication indicate mandatory adherence to the diet. Protein foods slow down the absorption of the drug and reduce its effectiveness. Do not eat easily digestible foods (baked goods, vegetables, dried fruits) before taking the medicine. The active substances do not have time to be absorbed into the blood and come out together with the feces.

Biseptol and alcohol are two incompatible things. Drinking alcohol increases the risk of developing allergic manifestations and reduces the effectiveness of treatment. The risk of poisoning increases, against which hepatitis is detected.

Patients with bronchial asthma and other severe forms of allergies (hay fever, hay fever, atopic dermatitis). The medication is prescribed under strict control to patients with thyroid diseases. It is not recommended to take it simultaneously with certain medications, so your doctor should be warned about them.

Taking diuretics increases the risk of bleeding and changes in blood composition.

If you have to take Biseptol 480 mg for a long time or there are changes in the blood, folic acid is prescribed in parallel at 5 - 10 mg per day.

Dosing of the drug

How to take Biseptol to get positive result and not cause harm to health? The dosage for patients over 12 years of age is equal to one 960 mg tablet (or two mg). Must be taken morning and evening. Depending on the course of the disease, treatment can last from one to two weeks. For adults, the dosage can be reduced to 480 mg. The suspension is prescribed in 20 ml doses. The medicine must be taken every 12 hours.

The children's version is presented as a suspension and sweet syrup. Instructions for use for children suggest strict adherence prescribed doses. Biseptol for younger children school age prescribed in a dosage of 480 mg or 5 ml of syrup twice a day. Biseptol for children preschool age prescribed in a dosage of 240 mg or 2.5 ml.

Biseptol contains trimethoprim and sulfamethoxazole. Instructions for use of the Biseptol suspension suggest giving the composition to babies with illnesses from three months. Up to six months of age, the dosage is 2.5 ml. In the future, the dosage can be increased to 5 ml. Biseptol suspension for children from 4 to 6 years old can be given in 5-10 ml doses. The medicine is given to the child after breakfast and dinner.

The instructions for the Biseptol suspension for children indicate that the duration of treatment is 10 - 14 days. The child swallows the medicine without problems, as it has a pleasant taste. The set includes a convenient measuring spoon.

After a year it is allowed to treat with Biseptol syrup. Up to two years, 120 mg of the drug is given twice a day; from 2 to 6 years, the dosage increases to 180 - 240 mg. Syrup for children over 6 years old is prescribed 240 - 480 mg of syrup.

The use of 240 mg tablets is allowed only after two years. Injections are allowed after 6 years.

The duration of treatment for children is five days and another two days after recovery. You cannot independently increase or decrease the prescribed dose, especially when treating pediatric patients.

Knowing all the features of using the drug Biseptol 480, you can avoid the development of unwanted reactions and achieve get well soon. You cannot use the medicine yourself, without examination and doctor’s recommendations.

By group affiliation, Biseptol belongs to the antibacterial drugs from the sulfonamide group. Its chemical composition successfully combines two active components such as trimethoprim and sulfamethoxazole, which have an inhibitory effect on the synthesis of substances, thereby suppressing the rapid proliferation of pathogenic microorganisms.

The drug has a wide spectrum of action, in particular, both gram-negative and gram-positive bacteria are sensitive to it. However, there are many pathogens that are very resistant to Biseptol, in particular, some fungi, pathogens of ureaplasmosis and tuberculosis, viruses, mycoplasmosis.

In addition, Biseptol suppresses the activity of Escherichia coli, which entails a sharp decrease in the synthesis of riboflavin, thiamine and nicotinic acid.

The medication is effectively absorbed from the gastrointestinal tract and almost completely, and its maximum concentration is noticeable within half an hour after administration. The therapeutic effect lasts up to 7 hours.

The antibiotic is available in the form of yellow tablets, suspension and solution for infusion.

Analogs of Biseptol are Expazol, Abatsin, Vanadil, Baktekod, Berlocid, Oriprim, Cotrimaxol, Methomide, Rancotrim, Sulfatrim and Trimezol.

Indications and contraindications for the use of Biseptol

Biseptol is prescribed for infectious and inflammatory pathologies caused by microorganisms that are hypersensitive to the antibiotic. These may be infections of the respiratory and genitourinary systems, otitis, sinusitis, gonorrhea, infections of the gastrointestinal tract, soft tissues and skin.

Contraindications to the use of Biseptol include abnormalities in kidney and liver function, hyperbilirubinemia in children, serious blood diseases, and glucose-6phosphate dehydrogenase deficiency. In addition, the drug is not recommended for use during pregnancy and lactation, as well as in children under three years of age. Restrictions also apply to persons with hypersensitivity to the active substances.

Prescribe Biseptol with caution for bronchial asthma, acute lack of folic acid in the body and thyroid pathologies.

Side effects and overdose of Biseptol

From the side of the central nervous system: migraines, dizziness, tremors of the limbs, apathy and peripheral neuritis.

From the respiratory system: suffocation, cough, bronchospasm.

From the hematopoietic system: eosinophilia, agranulocytosis, neutropenia, megaloblastic anemia, methemoglobinemia and other anomalies.

From the digestive system: symptoms of dyspepsia, loss of appetite, abdominal pain, gastritis, glossitis, stomatitis, hepatitis, pancreatitis.

Allergic reactions: skin manifestations varying degrees intensity, swelling and itching of the skin.

However, it is important to understand that in most clinical pictures Biseptol is well tolerated by the affected organism.

In case of overdose, a sharp exacerbation of all side effects is observed. In such cases, immediate discontinuation of the drug is required. therapeutic measures, in particular, gastric lavage, administration of calcium folinate and systematic monitoring of the patient’s condition.

Instructions for use of Biseptol

Daily doses are determined individually, but take the drug after meals with plenty of water.

Patients 3 - 5 years old are prescribed two tablets twice a day; 6 - 12 years - four tablets twice a day.

According to the instructions, for gonorrhea, the dosage of Biseptol is 2 g twice a day with a 12-hour break between doses.

The duration of the treatment course is from 5 to 14 days.

Features of using Biseptol

The drug is contraindicated during pregnancy and lactation.

Prescribe with caution if you are prone to allergies; In addition, such treatment requires systematic clinical control blood indicators.

During treatment with Biseptol, you should temporarily stop driving and engaging in intellectual work.

Drug interactions. Thus, in combination with thiazide diuretics, progression of thrombocytopenia and bleeding is observed. In addition, Biseptol enhances the effect indirect anticoagulants, activity of hypoglycemic drugs and methotrexate. Benzocaine, procaine, procainamide reduce the productivity of Biseptol.

Between diuretics and oral hypoglycemic agents, on the one hand, and sulfonamide antibiotics, on the other, there is a progression of the allergic reaction. PAS, phenytoin, barbiturates increase folic acid deficiency in joint use with Biseptol. Ascorbic acid, hexamethylenetetramine increase the risk of developing crystalluria. Biseptol reduces the effect of tricyclic antidepressants and also suppresses the effect of oral contraception.

Reviews of Biseptol, price

Reviews about Biseptol are contradictory. Some people think this medication very effective for eliminating internal infections, but others are sure that this antibiotic is obsolete, and it is better to choose its more effective and modern analogues. One way or another, only a knowledgeable specialist should prescribe an antibacterial therapy regimen.

Price for Biseptol tablets 480 mg, 20 pcs. – 250 rubles.

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Biseptol is for everyone famous antibiotic, which eliminates infections of the genitourinary and respiratory systems. It has been known for many years, and many doctors consider it to be morally outdated, but this does not diminish its relevance in modern medicine. general description Biseptol According to its group affiliation, Biseptol belongs to the antibacterial drugs from the sulfonamide group. Its chemical composition successfully combines [...]

Biseptol is a drug that has an effective bactericidal effect. It is used in the treatment of a wide range of diseases and only as prescribed by the attending physician. The drug is not an antibiotic, but belongs to the class of sulfonamides. Biseptol consists of active components that complement the therapeutic effect of each other: trimethoprim and sulfamethoxazole.

pharmachologic effect

Biseptol contains 2 main active substances - sulfamethoxazole and trimethoprim, which have an effective bactericidal and bacteriostatic effect.

The drug is active against Escherichia coli, streptococci, staphylococci, pneumococci, typhoid bacilli, Proteus and dysentery. But against Pseudomonas aeruginosa and tubercle bacilli, spirochetes and viruses, the drug is absolutely powerless.

Indications

The instructions for use of Biseptol indicate infectious and inflammatory pathologies of the body provoked by pathogens sensitive to the drug. Biseptol helps with the following conditions.

Infectious diseases of the respiratory system:

pneumonia;
acute and chronic bronchitis;
lung abscess;
pleural empyema;
bronchiectasis.

Diseases of the upper respiratory tract and throat diseases developed against the background of respiratory infections:

sinusitis;
angina;
otitis.

Infectious and inflammatory diseases of the genitourinary system:

Infectious diseases of the gastrointestinal tract:

dysentery;
diarrhea;
cholera;
typhoid fever.

Infectious diseases of soft tissues and skin:

pyoderma;
furunculosis.

Infectious diseases carried by animals and insects:

malaria;
brucellosis;
toxoplasmosis.

Severe forms of infectious and inflammatory diseases:

meningitis;
brain abscess;
osteomyelitis;
sepsis;
wound infections.

Biseptol is prescribed to children in cases of contraindications to antibiotics. Its most effective use is in the treatment of:

tonsillitis;
sinusitis;
respiratory infections (including pneumonia and bronchi);
inflammation of the middle ear;
intestinal infections;
infectious lesions of soft tissues;
furunculosis.

Release form

Biseptol is available in different forms:

Dosage

The course of treatment and dosage of Biseptol is selected individually by the attending physician, depending on the general health condition, age and concomitant diseases of the patient. In case of severe illnesses, the doctor has the right to double the dosage of Biseptol.

For children

Children from 6 months to 5 years are usually prescribed a syrup or suspension. The recommended dose is 5 milliliters of suspension 2 times a day.

Children who are able to swallow a tablet should take 2 tablets (120 milligrams) twice daily.

Children from 6 years of age are prescribed Biseptol tablets 480 milligrams twice a day.

For adults

For patients over 12 years of age, Biseptol is prescribed at a dosage of 960 milligrams twice a day.

For pneumonia

For gonorrhea

The drug is taken 2 grams (in terms of sulfamethoxazole) twice a day with an interval of 12 hours.

For cystitis

For sore throat

Biseptol is prescribed in the recommended age dosage for 5-10 days. Although recently, Biseptol has been prescribed less and less frequently for angina, since studies show that the causative agents of the disease (streptococci and staphylococci) lose sensitivity to this drug.

Admission rules

A 12-hour interval should be strictly observed between doses of the drug.
Biseptol should be taken only after meals, as the medicine irritates the walls of the stomach.
The course of therapy must be at least 5 days, otherwise a complication may develop.
During the treatment period, it is important to exclude protein foods from the diet; they reduce the effectiveness of the drug and complicate its absorption. And also give up alcoholic beverages.

Failure to comply with these rules may lead to a decrease in the effectiveness of Biseptol or side effects.

Contraindications

Damaged liver parenchyma and severe liver failure;
Renal dysfunction and renal failure;
Hematopoietic disorders and severe blood diseases (agranulocytosis, aplastic anemia, leukopenia, megaloblastic anemia, B12-deficiency anemia);
Pregnancy and lactation;
Age up to 3 months;
Hyperbilirubinemia;
Jaundice in children;
Lack of glucose-6-phosphate dehydrogenase;
Hypersensitivity to the composition of the drug.

Biseptol is prescribed with extreme caution for:

diseases of the thyroid gland;
bronchial asthma;
hay fever;
atopic dermatitis;
lack of folic acid in the body.

Side effects

According to studies, in most cases Biseptol is well tolerated. However, after long-term use of the drug, there is a possible risk of developing candidiasis and thrush. Against the background of concomitant pathologies and the body’s sensitivity to the drug, the following side effects may occur.

Nervous system disorders:

apathy;
depression;
aseptic meningitis (caused by bacteria);
severe and prolonged headaches;
dizziness;
tremor (involuntary contractions of the muscles of the trunk or limbs);
peripheral nerve inflammation.

Gastrointestinal tract dysfunctions:

Respiratory system disorders:

inflammatory allergic reaction of lung tissue;
cough;
bronchospasms.

Disturbances in the functioning of the circulatory system and complications in hematopoiesis:

thrombocytopenia (reduced number of platelets in the blood);
neutropenia (reduction or absence of granulocytes in the blood);
leukopenia (decreased white blood cells);
megaloblastic anemia.

Problems of the urinary system:

polyuria (increased production of urine);
hematuria (the appearance of blood in the urine);
increased urea concentration;
crystalluria (presence of salts in urine);
kidney dysfunction.

Painful manifestations from the musculoskeletal system:

muscle pain;
joint pain.

Manifestation of allergic reactions: