home Calculators Fenistil allergy cream. Use in elderly patients. Therapeutic effects and action

Fenistil allergy cream. Use in elderly patients. Therapeutic effects and action

Children different ages suffer from allergies caused by food, medications, insect bites, etc. This problem is especially relevant for infants. An allergic reaction is manifested by red spots on the skin, itching, swelling, and irritation of the mucous membranes. It is important to protect the child from the pathogen, and medications will help eliminate unpleasant symptoms.

Fenistil is a popular antihistamine, which quickly eliminates negative manifestations allergies. The medication reduces sensitivity cell receptors to histamine. Whether the drug can be given to infants will be discussed further.

Fenistil for newborns: description of dosage forms

The antihistamine is available in the form of drops, capsules, emulsion and gel. For children, drops and gel are used, which have the following composition:

Fenistil gel for newborns, colorless with a neutral aroma:

Fenistil drops are transparent and odorless:

When an allergen enters the body, antibodies begin to be produced. Upon repeated contact with the pathogen, histamine is produced, which enters the bloodstream, causing a rash, swelling and itching.

Fenistil reduces the susceptibility of cellular receptors to histamine. Thanks to the action of the drug, the capillaries become stronger, the inflammatory process and pain. As a result, allergy symptoms disappear.

Oral drops have a systemic effect, the therapeutic effect appears half an hour after administration, and they act for 12 hours. The gel is applied externally, and about 10% penetrates into the blood active component. Therapeutic effect external remedy appears almost immediately and lasts from 3 to 4 hours.

Indications

Fenistil for newborns in the form of drops is prescribed in the following cases:

Chronic runny nose of allergic origin.
Allergy to medications.
Nettle fever.
Angioedema.
Food allergies.
Allergic cough.
Itching caused by chickenpox, dermatitis, eczema, insect bites, etc.
Colds, such as laryngitis (to relieve symptoms such as irritation of the throat mucosa).
(symptomatic treatment).

The gel is prescribed to eliminate external symptoms allergies:

Itching on the skin due to nettle fever, dermatosis.
Itchy skin rash due to chickenpox, rubella, dermatitis.
Sun or household burns.
After insect bites.
Lichen.

Some doctors advise taking drops for 3 days after vaccination to prevent allergies. However, not all pediatricians approve of this practice, explaining that if the child does not have a predisposition to diathesis, then there is no need to give him the drug.

Application and dosage

Fenistil drops are intended for children from 1 month.

According to the instructions for use, the daily dosage for children under one year of age is as follows:

up to 12 months – from 3 to 10 drops;
from 1 to 3 years – from 10 to 15 drops;
from 3 to 12 years – 15 or 20 drops;
from 12 years and older – from 20 to 40 drops.

The drug is taken three times a day, the final dosage is determined by the pediatrician after the diagnosis has been established.

You can calculate the daily dose of medication for allergies yourself:

The dose is determined by the calculation of 1 kg of weight/0.1 mg of dimethindene. For example, a child’s weight is 5 kg, then 5 (kg) x 0.1 (mg) = 0.5 mg of dimethindene should be received by the baby in 24 hours.
1 ml of the drug contains 1 mg of the main component, so the baby should receive 0.5 ml of the drug.
1 ml of the drug contains 20 drops, 0.5 ml x 20 = 10 drops per day.
The daily portion is divided into 3 times: 10 drops: 3 doses = 3 drops.

Thus, a patient weighing 5 kg should take 3 drops of Fenistil three times. The medicine is given before or after meals. Before use, the medication should not be heated, as its effectiveness will decrease.

For newborns aged 1 month, the drug is diluted with breast milk or formula, for a child 6 months old - with juice or compote. Children 12 months and older take the drops pure form, they taste good.

Fenistil is used until allergy symptoms disappear; the shorter the therapeutic course, the better. The gel is used for newborns to eliminate external.

Rules for using the gel:

To eliminate skin rashes, the product is applied in a thin layer to the damaged area. The frequency of the procedure is from 2 to 4 times in 24 hours.
After treatment, you should avoid the sun.
Only the skin (forehead, cheeks, chin) is treated with the gel; the product should not come into contact with the mucous membranes.
Treatment lasts until symptoms disappear completely. If after 4 days of using the gel the patient’s condition has not improved, then you should contact your pediatrician.

Before applying the gel to delicate skin child, you need to clean your hands with antibacterial soap.

special instructions

Fenistil for infants is contraindicated in the following cases:

Patients under 1 month of age, premature or low birth weight infants. The likelihood of respiratory arrest increases.
Hypersensitivity to the components of the drug.
Angle-closure glaucoma.
Lung diseases.
Bladder diseases.
Impaired functionality of the gallbladder.

As the dosage increases or there is a contraindication, the likelihood of side effects: lethargy, dizziness, dryness inner shells, skin rash and tissue swelling. Some patients experience nocturnal breathing (temporary cessation of breathing) for up to 12 months. After using the gel, the skin may dry out, burning, itching, and rash may occur.

If used for too long, the likelihood of seizures, disorders heart rate, the child becomes lethargic and decreases physical activity, reflexes become dull. If such symptoms appear in an infant, you should stop taking it. medicine and contact your pediatrician.

Similar anti-allergy products

If there is a contraindication in a child, Fenistil can be replaced with antihistamines with a similar mechanism of action. However, choosing a drug for a patient younger than 12 months is quite difficult, since many antiallergic drugs are intended for children 6 months and older.

Popular analogues:

Antihistamine syrup Erius with desloratadine is used for patients over 1 year of age; it rarely causes adverse reactions.
Agistam is a tablet based on loratadine against allergies, intended for children over 2 years old.
Suprastinex in the form of drops with levocetirizine is prescribed to children from 2 years of age.
Zyrtec drops based on cetirizine are used to eliminate allergy symptoms in a child over 6 months old.

Your doctor will help you choose the right analogue. The average price for Fenistil drops is 400 rubles, and the gel can be purchased for 350 rubles.

Thus, Fenistil is an effective antihistamine that eliminates allergy symptoms. The drug eliminates rash, itching, and swelling of tissues. To ensure that the treatment is only beneficial, you should consult a pediatrician before using the medication to treat a newborn.

Thank you

Fenistil is a drug intended to treat allergy symptoms. According to the mechanism of action, the medicine belongs to the group of non-selective (non-selective) histamine blockers. Non-selective blocking of histamine receptors is a property of first generation drugs, which include Fenistil.

Today, Fenistil is an antiallergic and antipruritic agent intended for use internally or externally. The medicine is symptomatic because it does not treat the cause, but only eliminates characteristic features various diseases allergic nature (for example, hay fever, rhinitis, urticaria, eczema, dermatitis, etc.).

Release forms and composition

Today Fenistil is available in various dosage forms that can be used both internally and externally. On the domestic pharmaceutical market The following dosage forms of the drug are available:
1. Fenistil drops.
2. Fenistil gel.
3. Fenistil capsules.

Drops and gel are worn trade name Fenistil. The dosage form for oral use is capsules, often called simply tablets. That is why it is quite fair to put an equal sign between the names of “tablets” and “capsules” Fenistil. The correct commercial name of the capsules is Fenistil 24.

As active substance All dosage forms of Fenistil contain the same chemical compound - dimethindene. Quantitative content of dimethindene in various forms release of Fenistil:

Drops contain 1 mg per 1 ml of solution.
The gel contains 1 mg per 1 g, which is a concentration of 0.1%.
Capsules – each contains 4 mg.

Excipients in Fenistil preparations vary depending on the dosage form. We list only those components that can cause an allergic reaction:

Drops – propylene glycol, sodium saccharinate, benzoic acid.
Gel – propylene glycol, carbopol 974R.
Capsules - lactose, starch, glutamic acid, silicone emulsion, titanium dioxide, gelatin.

Drops are produced in dark glass bottles of 20 ml, equipped with a dropper - dispenser. The gel is packaged in tubes of 30 g. Capsules are produced in packs of 10 pieces.

Fenistil Pencivir

There is a drug that is correctly called Fenistil Pencivir. Usually the second word in the name is simply omitted. This cream is also often called ointment, so in this case “cream = ointment”. But Fenistil Pencivir cream is an antiviral, not an antiallergic drug, the name of which is confusing.

Therapeutic effects and action

Fenistil blocks histamine receptors located on cells. As a result, histamine does not transmit a signal into the cells, which leads to the release of a huge amount of biologically active substances. In the classic development of allergies, these biologically active substances lead to the development of familiar symptoms - itching, swelling, redness or rash, etc. That is, Fenistil simply blocks one of the stages allergic reaction, which cannot develop further.

However, Fenistil is a purely symptomatic remedy, since it does not affect the causes of allergies, eliminating only its manifestations. In other words, under the influence of the allergen, histamine continues to be released, but it cannot cause further stages of the hypersensitivity reaction with the formation characteristic symptoms, since receptors for it on the surface of cells are blocked. In addition to blocking histamine receptors, Fenistil reduces capillary permeability, which prevents the release of fluid into the tissue and the formation of edema.

The drug has two main therapeutic effects - antiallergic and antipruritic. These effects are used to relieve allergy symptoms.

Separately, it should be said about Fenistil Pencivir cream, which is an antiviral drug used to treat herpetic rashes on the lips.

Indications for use

Fenistil drops and capsules have same readings for use, which is the presence of the following conditions:

hives;
hay fever(hay fever);
year-round allergic rhinitis;
food allergies;
drug allergies;
Quincke's edema;
itchy skin of various origins(for example, for eczema, chickenpox, measles, rubella, insect bites, dermatitis, etc.);
prevention of allergy development as part of complex hyposensitizing therapy.

Fenistil gel is used externally, so the range of indications for its use is somewhat narrower compared to tablets and drops.

So, Fenistil gel is used to treat the following conditions:
1. Itchy skin against the background of dermatosis and urticaria.
2. Skin itching of various origins, except those caused by cholestasis.
3. Itching developing in the background skin rashes, for example, with chickenpox, measles, etc.
4. Itching due to insect bites.
5. Minor burns (household or sunburn).

Fenistil - instructions for use

The use of Fenistil internally and externally has certain differences. Therefore, we will consider the rules for using various dosage forms of Fenistil separately.

Fenistil drops

Adults and adolescents over 12 years of age should take the drug in an amount of 3–6 mg per day, which corresponds to 60–120 drops. This amount of the drug must be divided into three doses, that is, drink 20 - 40 drops three times a day. If it is not possible to drink drops three times a day, the daily dose should be divided into two doses.

If a person has a tendency to drowsiness, then in the evening he should drink large dose, and in the morning - less. For example, in the morning and at lunch - 20 drops of Fenistil, and in the evening, before bed - 40 drops.
Fenistil drops are allowed to be taken by children from 1 month. The dose of drops for children depends on age:
1. 1 month – 1 year: take 3 – 10 drops at a time (maximum daily dose – 30 drops).
2. 1 – 3 years: take 10 – 15 drops at a time (maximum daily dose - 45 drops).
3. 3 – 12 years: take 15 – 20 drops at a time (maximum daily dose – 60 drops).

Drops should not be heated before use, as the drug will lose its therapeutic properties. For infants, drops can be added to milk or formula. For older children, the drops are poured into a spoon and given undiluted. The child calmly swallows them, since the drug has a pleasant taste.

When taking Fenistil drops, adults should remember that they have sedative effect. Therefore, if it is necessary to perform work that requires concentration or fast response, the dose should be reduced as much as possible.

Overdose of Fenistil drops manifests itself in the form of the following symptoms - drowsiness and inhibition of the central nervous system in adults, and agitation in children. The following symptoms are typical for both adults and children:

To treat an overdose, the remaining drug should be removed from the body. To quickly eliminate Fenistil from the body, you should drink a sorbent (for example, activated carbon, Polyphepan) and a saline laxative. If necessary, symptomatic agents are used.

Interaction with other drugs. Fenistil significantly enhances the effects of sleeping pills, anti-anxiety drugs and antidepressants. Alcoholic drinks while taking Fenistil, the speed of psychomotor reactions significantly slows down.

Fenistil tablets (capsules)

The drug in capsule form is allowed to be used only from 12 years of age. The dosage for adults and adolescents over 12 years of age is the same. Usually 1 capsule is prescribed once a day, since the duration of action of Fenistil is 24 hours. It is best to take the drug in the evening, before bed, so as not to experience drowsiness during the day. If a person works shifts, the drug should be taken before going to bed.

The capsule must be swallowed whole, without chewing, with a small amount of clean water. Maximum permissible duration The course of taking Fenistil capsules is 25 days.

For the treatment of allergic, infectious (for example, chickenpox, measles, etc.) and other rashes on the child’s skin, the gel is applied to the affected areas 2 – 4 times a day, in a thin layer. In this case, it is necessary to protect the treated skin areas from exposure to direct sun rays. When treating the skin of the cheeks, forehead or chin, avoid getting the gel in the eyes and mouth. The course of treatment lasts until the rash disappears completely. However, if after 3 to 4 days of regular use of Fenistil there is no improvement, you should stop using the gel and consult your doctor.

Fenistil gel and drops for newborns - instructions for use

The gel can be used from birth, and drops only from 1 month. However, Fenistil should be given to newborns only when indicated, when an allergic reaction has actually developed. You should not overuse the drug if any minor red spots appear on the child’s skin, which often have nothing to do with allergies. Parents should remember that every spot, redness or rash has a reason that needs to be established, and not immediately rush into battle with this symptom, trying to get it out of sight as soon as possible so that it does not cause concern.

Remember that Fenistil is a first generation drug antihistamines, so it acts on receptors in the central nervous system, causing severe drowsiness as a side effect. In children, the drug can cause convulsions, respiratory arrest, arrhythmia and palpitations. In addition, the inhibitory effect of Fenistil on the central nervous system inhibits the child's development and reduces learning ability. This should be remembered by all parents who decide to give Fenistil to their newborn child. If it is necessary to use antihistamines for a newborn, it is better to choose second and third generation drugs, for example, Zyrtec, Erius, Telfast, Claritin, etc. These drugs act selectively without affecting receptors in the central nervous system.

As a rule, most parents, in response to the information provided, will say: “But the instructions for Zyrtec say that it can only be used from 6 months, and Fenistil - from 1 month, which means it is safer!” Alas, this is not true. The fact is that the instructions for Zyrtec were written in the age of evidence-based medicine, when before introducing into practice, each medicine is tested, indications, contraindications and side effects are verified. After introducing the medicine into practice, it is monitored and all side effects are also carefully recorded. To write only one phrase “can be used from 1 month”, it is necessary to conduct studies in which at least 10,000 children will participate. For obvious reasons, this is not done. After years of observation, when sufficient information has accumulated indicating the safety of the drug, manufacturers will have the opportunity to write in the instructions a phrase about the possibility of use for newborns.

But the instructions for Fenistil were written before the introduction of such strict rules, so no one monitors the drug, does not register numerous side effects, etc. Therefore, this phrase “can be used from 1 month” remained, which was written on the basis of exclusively theoretical data. For example, in Europe and the USA, first-generation histamine blockers (including such widespread ones as Fenistil, Suprastin and Tavegil) are prohibited for use in children under 12 years of age.

However, you should not consider Fenistil an absolute evil, since the drug perfectly relieves allergy symptoms, especially when they are severe. You just need to use it carefully and strictly according to indications. Children under 1 year of age should take 3 to 10 drops three times a day. The maximum daily dose is 30 drops. How less weight child - the fewer drops should be given. It is better to calculate the exact number of drops needed per day based on the child’s body weight, based on the ratio: 0.1 mg per 1 kg of weight. For example, if a child’s weight is 7 kg (9 – 10 months), then he needs 0.1 mg * 7 kg = 0.7 mg of Fenistil per day. We convert milligrams into drops according to the ratio: 20 drops = 1 mg, that is, 0.7 mg = 14 drops. The resulting amount is divided into three doses per day. The drug should be taken until the symptoms disappear. But if after 5 - 7 days of regular use of the drops there is no improvement in the condition, you should stop taking it and consult a doctor.

Fenistil gel can be used to eliminate itching and rashes of an allergic, infectious or burn nature on the skin of newborns. The drug is applied in a thin layer to the skin 2 – 4 times a day. The course of treatment is continued until the symptoms disappear. If rashes appear in a newborn, you should first try to eliminate them with gel, and only then add drops.

Use during pregnancy

Fenistil drops and gel are contraindicated for women in the first trimester of pregnancy (up to 12 weeks). From the 13th week of pregnancy until its end, drops and gel can be used by a woman only if the benefit outweighs the potential risk to the fetus. The gel should not be applied to large areas of skin, to areas with bleeding wounds or severe irritation.

Fenistil capsules can be used by pregnant women only when there is a threat to life - for example, the development of Quincke's edema, etc.

Pregnant women with allergies or prone to hypersensitivity reactions should choose safer selective histamine blockers of the second and third generations (for example, Erius, Telfast, Claritin, Zodac, Zyrtec, etc.).

How much should I take?

In general, you should be guided by the rule - the less, the better! For acute allergic reactions, Fenistil is given short courses for 7–10 days to relieve painful symptoms. If allergy symptoms go away faster (for example, after 2 days), then you can stop taking it. We can say that Fenistil is a remedy for relieving acute allergic reactions, which is used in short courses.

When using capsules for prevention seasonal allergies continuous use is allowed for 25 days. But it's better to avoid this long-term use Fenistil, if possible, choose another antihistamine that is better suited for prevention.

Fenistil before vaccination

Today, many pediatricians recommend giving a child Fenistil as preparation for vaccination. This tactic is based on the desire to reduce reactions to the vaccine so that parents and doctors feel safer. In principle, any histamine blocker, including Fenistil, can indeed reduce the severity of the reaction to the vaccine, but in this situation the question should be posed differently: “Is it even necessary to carry out such preparation and reduce the severity of the reaction?”

Scientists - vaccinologists, specialists from the World Health Organization, the American Medical Association and the European United Clinics consider the tactics of using antihistamines to reduce the reaction to vaccination to be unjustified, risky and harmful. Experts believe that an antihistamine should be given only if a strong reaction develops after vaccination in order to eliminate it. But this should not be done in advance, before the injection, since such “preparation” tactics lead to erasing the reaction, incorrect interpretation of the results and latent flow allergies that may manifest themselves with great force in the future. In a word, by giving the child Fenistil before vaccination, parents want to relieve themselves of responsibility and eliminate the need to monitor the baby after the injection. Adults want to feel calm and confident, so they prefer to give the child medicine in advance, “just in case.” This behavior can be compared to the preventive use of anti-cold medications when a person is still completely healthy.

However, if there is a desire to carry out medicinal preparation, Fenistil is given to the child for 3 to 5 days before and after vaccination. Typically, for children under 1 year of age, the dosage is 4–5 drops, twice a day. Children from 1 to 3 years old take 10 drops, 2 times a day. For prevention, children over 3 years old will have to be given 20 drops of Fenistil, three times a day.

Side effects

Fenistil drops and capsules have the same side effects various organs and systems. Gel as side effects only calls local reactions. All side effects of Fenistil drops, gel and capsules are reflected in the table:

Analogs

Today, Fenistil on the domestic pharmaceutical market has only analogue drugs that have similar therapeutic effects, but contain different Chemical substance as an active component. The following drugs are analogues of Fenistil:

The original medicine fenistil (INN - dimethindene) from the Swiss pharmaceutical company Novartis Consumer Health represents a group of first-generation H1 antihistamines. By blocking H1-histamine receptors, it prevents the development of allergic reactions, thereby providing a pronounced antiallergic effect. Fenistil’s “hit list” includes not only the above receptors: it is capable of removing the body from the influence of other mediators involved in allergic processes, for example, serotonin and bradykinin. The drug significantly reduces the increased permeability of capillary walls caused by an allergic reaction and prevents the strengthening of immediate allergic reactions associated with the secretion of additional amounts of histamine. Fenistil does not have a toxic effect on the heart, and is generally considered safe drug, which makes it possible to use it in children. Among the main advantages of the drug, its manufacturer (and this is a company quite respected in the global pharmaceutical community) claims a broad spectrum of action (including antiallergic, antipruritic and antiexudative effects) and a rapid onset of development pharmacological effect, the peak of activity of which is measured 15-45 minutes from the moment of administration. Another advantage stands out: fenistil is adapted for use in pediatric practice. So, this is, in fact, the only antihistamine produced in drops for oral administration: this “children’s” form of release allows you to accurately measure the required amount of the drug, fortunately, the bottle is equipped with a special dropper dispenser for selecting an individual dose.

To this should be added a pleasant taste, even in the absence of sugar and flavorings. Drops are recommended to be dissolved in heated nutritional mixture or give directly from a spoon before feeding. Fenistil has pronounced antipruritic properties, which makes it an effective remedy for insect bites and infectious rashes: with his active participation, swelling, hyperemia and pain characteristic of the above conditions will recede into the background.

As for side effects, fenistil is not a leader here in the bad sense of the word. The sedative effect, which is often reproached with first-generation antihistamines, is rather weakly expressed and is quite comparable with more modern drugs. In addition to drops, fenistil is available in two more dosage forms, but for local application: gel and emulsion. The gel is convenient in the sense that it has an additional cooling effect. For extensive lesions skin allergists recommend combining the use of drops with the use of one of the external forms of the drug, while in pediatric practice they strive to minimize the area of skin exposed to gel treatment. After applying the latter, the treated areas of the skin should not be exposed to sunlight. The oral form of the drug does not combine well with tranquilizers, sleeping pills and alcohol, because potentiates their action.

Pharmacology

Histamine H1 receptor blocker is a competitive histamine antagonist. Has antiallergic and antipruritic effects. Reduces increased capillary permeability associated with allergic reactions.

It also has an antibradykinin and weak m-anticholinergic effect. When taking the drug during the day, a slight sedative effect may be observed.

Pharmacokinetics

Suction

After oral administration, it is absorbed quickly and quite completely. Cmax in blood plasma is achieved within 2 hours. Bioavailability is about 70%.

Distribution

Protein binding is about 90%. Penetrates well into tissues.

Metabolism

Metabolized in the liver by hydroxylation and methoxylation.

Removal

T1/2 is 6 hours. Excreted in bile and urine (90% as a metabolite, 10% unchanged).

Release form

Drops for oral administration in the form clear liquid, colorless, practically odorless.

Excipients: sodium hydrogen phosphate dodecahydrate - 16 mg, citric acid monohydrate - 5 mg, benzoic acid - 1 mg, disodium edetate - 1 mg, sodium saccharinate - 0.5 mg, propylene glycol - 100 mg, purified water - 888.5 mg.

20 ml - dark glass bottles (1) with a dropper dispenser - cardboard packs.

Dosage

The drug is taken orally.

For adults and children over 12 years of age, the daily dose is usually 3-6 mg (60-120 drops), divided into 3 doses (i.e. 20-40 drops 3 times a day).

For children aged 1 month to 12 years, daily doses are given in the table. Frequency of application - 3 times/day.

20 drops = 1 ml = 1 mg of dimethindene.

Overdose

Symptoms: central nervous system depression and drowsiness (mainly in adults), central nervous system stimulation and m-anticholinergic effects (especially in children), incl. agitation, ataxia, tachycardia, hallucinations, tonic or clonic convulsions, mydriasis, dry mouth, flushing, urinary retention, fever, decreased blood pressure, collapse.

Treatment: should be prescribed Activated carbon, saline laxative; take measures to maintain the function of the cardiovascular and respiratory systems (do not use analeptics).

Interaction

Fenistil ® enhances the effect of anxiolytics and hypnotics.

At simultaneous administration ethanol, there is a slowdown in the speed of psychomotor reactions.

MAO inhibitors enhance the anticholinergic and depressant effects on the central nervous system.

Tricyclic antidepressants and anticholinergic drugs increase the risk of increased intraocular pressure.

Side effects

From the side of the central nervous system: drowsiness (especially at the beginning of treatment), dizziness, agitation, headache.

From the outside digestive system: nausea, dry mouth.

From the respiratory system: dry throat, dysfunction of external respiration.

Other: swelling, skin rash, muscle spasm.

Indications

allergic diseases (urticaria, hay fever, year-round allergic rhinitis, food and drug allergy, angioedema);
skin itching of various origins (eczema, other itchy dermatoses / incl. atopic dermatitis/, itching with measles, rubella, chicken pox, insect bites);
prevention of allergic reactions during hyposensitizing therapy.

Contraindications

angle-closure glaucoma;
bronchial asthma;
prostatic hyperplasia;
children up to 1 month;
I trimester of pregnancy;
lactation period ( breastfeeding);
hypersensitivity to the components of the drug.

Fenistil ® should be prescribed with caution to patients with chronic obstructive pulmonary diseases; children under 1 year of age (since their sedation may be accompanied by episodes of sleep apnea).

Features of application

Use during pregnancy and breastfeeding

Fenistil ® is contraindicated in the first trimester of pregnancy and during lactation (breastfeeding).

The use of Fenistil in the second and third trimesters of pregnancy is possible under the supervision of a physician, only if the expected benefit to the mother outweighs the potential risk to the fetus.

Use in children

Contraindicated: children under 1 month of age (especially premature infants). Fenistil ® should be prescribed with caution to children under 1 year of age, because in them, sedation may be accompanied by episodes of sleep apnea.

special instructions

Drops should not be exposed to high temperatures.

Upon appointment infants they should be added to a bottle of warm baby food immediately before feeding. If the child is already being spoon-fed, the drops can be given undiluted. The drops have a pleasant taste.

When using Fenistil in children under 1 year of age, you should consult a doctor and use it only if there are indications for the use of histamine H1 receptor blockers.

The drug is not effective for itching associated with cholestasis.

Impact on the ability to drive vehicles and operate machinery

Fenistil ® may impair attention, so it should be taken with caution when driving a car, operating machinery, or performing other types of work that require increased attention.

A fairly common health problem in both adults and children is, which is accompanied by a mass unpleasant symptoms. One of effective means Fenistil in the form of drops is considered to eliminate such signs.

The product prevents allergic phenomena such as itching, rashes, and sneezing. In addition, it is accessible to all ages and comes in several forms.

The active component of the drug Fenistil is dimethindene maleate. For one milliliter of product its content is one milligram.

TO excipients medications include:

Fentistil is a drug from the group of antihistamines. Drops have an effect on human body the following actions:

Relieves symptoms of an allergic reaction.
Eliminate itching.
Reduces high permeability of small blood vessels, which prevents the development of edema.
Suppresses the effect of histamine H-receptors on the blood.

It is important to note that Fenistil is used as symptomatic drug, that is, it does not affect the development factors of allergies, but relieves its symptoms - itching, rash, sneezing, swelling.

Fenistil is available in several forms:

Drops. The liquid, found in dark glass bottles, is transparent, without a pungent odor. The volume of the bottle is 20 milliliters. The cardboard box also contains a dropper - a dispenser.
Capsules. Available in blisters of ten pieces.
Gel. The medicine in this form is in thirty gram tubes.

It is recommended to store the drops in a place inaccessible to children and with minimal exposure to sunlight. The optimal temperature for storage is no higher than thirty degrees. The bottle should also be placed in a cardboard package.

The drops are suitable for use for three years from the date of manufacture. If this period has expired, the drops cannot be used.

Indications for use of drops

Experts usually prescribe Fenistil for allergic diseases, such as:

Hay fever - hay fever.
Quincke's edema.
Angioedema.
Hives.
Allergic reactions to medications and food.

Drops also treat itching of various etiologies. Therefore, a drug is often prescribed to eliminate this symptom for the following diseases:

Atopic dermatitis.
Dermatosis.
Eczema.
Chicken pox.
Rubella.
Diathesis.
Measles.
Relieves drops and itching after insect bites.

Fenistil is often used to prevent allergies during hyposensitizing treatment.

Directions for use and dosage

The daily dose of drops for adult patients is from three to six milligrams ( maximum dose per day - one hundred and twenty drops). Therefore, Fenistil should be taken three times a day, from twenty to forty drops at a time. You can also take drops twice a day up to three milligrams per dose (up to sixty drops).

Usually the dosage is selected individually depending on the severity of the disease, age criterion and characteristics of the body. For example, people who feel drowsy after taking an antihistamine are prescribed a lower dose in the morning and an increased dose at bedtime.

Regarding children's age, drops can be taken from one month of age. The dose at one time depends on the degree of maturity:

From one month to a year – 4 – 10 drops
Up to three years – from 10 to 15 drops
Up to twelve years – from 15 to 20 drops

It is recommended to drink Fenistil three times a day. In addition, to avoid overdose, childhood The dosage is set by a specialist, focusing on the patient’s body weight (per kilogram of weight, the recommended dose of drops is 0.1 mg).

Useful video - Allergic rhinitis:

The instructions for the product indicate the following features of the use of Fenistil:

The product should never be heated before use.
You can dilute the drops in the mixture or breast milk- for babies.
Children of preschool and school age the drug is not diluted.
Use the medicine with caution before work with increased concentration, since the drops may cause drowsiness.
As for the use of Fenistil during pregnancy, only a specialist can decide on the advisability of taking them.

Drops are used until the symptoms of an allergic reaction disappear. If there is no therapeutic effect for up to seven days, it is recommended to stop using the drug and consult a doctor about the possibility of using analogues.

Contraindications

There are some restrictions regarding the use of Fenistil drops. Such contraindications include the following pathological conditions:

Bronchial asthma.
Angle-closure glaucoma.
Prostate hyperplasia.

The drug should not be used by children under one month of age, during pregnancy (first trimester) and breastfeeding. Fenistil drops are not prescribed to premature babies.

Some sources contain information that it is advisable not to take the drug for children under one year of age. Since it has a sedative effect, infants may develop sleep disorders and periodic respiratory arrest. The decision to use drops for an infant should be made by a doctor.

Hypersensitivity to the components of the drops is also considered a contraindication.

For patients with obstructive pulmonary diseases and children under one year of age, the drug is prescribed with caution.

Overdose and side effects

Usually, an overdose is extremely rare - and only if the instructions are not followed and the recommended doses of the drug are not followed.

The main signs of an overdose of drops are:

When such symptoms appear, it is necessary to remove the remaining product from the body as quickly as possible. For this, various sorbents (Enterosgel, activated carbon) and laxatives are used. Medicines are also used to relieve symptoms of overdose.

Among the most common side effects from using Fenistil is drowsiness. In children, on the contrary, excitation of the central nervous system may occur. Its oppression is also possible.Most common adverse reactions the following phenomena are considered:

If such symptoms appear, you should stop taking the drug and consult a doctor, who will normalize the dosage and prescribe Fenistil substitutes that are identical in indications and effects.

To prevent an allergic reaction or in a situation where the child has already developed an allergy, drugs from the group of antihistamines are prescribed. One of the most popular drugs of this group in children is Fenistil. It is often prescribed to children in the form of drops, so parents should know in what cases such a medicine is indicated, at what age it is permissible to use it, and what dosages of Fenistil are used for children.

Features of Fenistil in drops

This dosage form Available in a dark glass bottle with a capacity of 20 ml, supplemented with a special dispenser.
The liquid inside the bottle is transparent, odorless, with a sweet taste.
The medicine is safe for infants, so doctors often prescribe it for allergies in children older than 1 month.
The drops are convenient to dose and easy to mix with baby food or drink.
Active substance V this drug is dimethindene maleate. One milliliter of Fenistil drops contains 1 mg of this active ingredient.
1 ml of the drug contains 20 drops.
Additional substances Fenistil drops contain water, sorbitol, a preservative, ethanol, sodium dehydrogenphosphate. Also in pharmacies there is Fenistil New, the main difference of which is the absence of ethanol in its composition.
The medicine is produced not only in drops, but also in the form of a gel, as well as in capsule form.
Store Fenistil drops at a temperature no higher than +25ºС in a place where a child cannot reach. Once opened, the bottle can be stored for up to 24 months.

Fenistil is available in drops, gel and capsule form

Action

The drug blocks receptors that are sensitive to a compound released during allergies - histamine. In healthy children, this compound is located inside the cells, but when pathological process, for example, when exposed to an allergen, histamine begins to be actively released into the blood. The result of this process is swelling of tissues, spasms of smooth muscles, stagnation of blood in small vessels, itching and other allergy symptoms.

When taking Fenistil, the production of histamine is suppressed, so itching decreases, capillary permeability decreases, which leads to the elimination of swelling and other uncomfortable symptoms. Dimetindene begins to act half an hour after application, and maximum effect observed after two hours.

Indications

The drug is often prescribed with for preventive purposes, for example, after vaccination or before vaccination, if the baby has a tendency to allergies.

Contraindications

Fenistil drops are not prescribed if the child has:

Intolerance to any component of the drug.
Bronchial asthma.
Angle-closure glaucoma.

It is also important not to forget that the drug is not used in the neonatal period, since it age limit is 1 month old. At the same time, babies up to 12 months and with chronic pathologies respiratory system, the medicine is prescribed with caution to prevent nighttime apnea attacks.

Side effects

Most common side effect Fenistil in the form of drops causes drowsiness. In most babies it appears in the first days of treatment, and then often goes away. In addition to drowsiness, children taking this antihistamine may experience:

Fenistil has its side effects, which you need to familiarize yourself with before taking it orally.

Dosage: how many drops to drop?

The required dosage Fenistil is often calculated based on the child's weight. The number of kilograms of the child’s body weight is multiplied by 2 and the number of drops is obtained, which represents the daily dose. It is divided into 3 doses, receiving single dosage for a specific child.

The average dosages of Fenistil in the form of drops are:

In the first year of life (from 1 to 12 months) - 3-10 drops, taking into account the child’s weight, per dose, a total of 9-30 drops per day.
For children over a year old up to 3 years of age - 10-15 drops at a time, the daily dosage is from 30 to 45 drops.
At the age of 3-12 years - from 15 to 20 drops per dose, in total from 45 to 60 drops per day.
Children over 12 years old - from 60 to 120 drops as daily dose, that is, 20-40 drops per dose.

If Fenistil is taken before vaccination, the medicine is given to the child 3-5 days before vaccination in the following dose:

For children under one year old - 4-5 drops in the morning and evening.
Children aged 1-3 years - 10 drops twice a day.
For a child over three years old – 20 drops three times a day.

If the drug causes severe drowsiness in the baby, daily dosage medications can be divided into doses so that most The child received the drug before bedtime. For example, a child needs to be given 40 drops of Fenistil per day. You can give 10 drops in the morning, 10 drops at lunch and 20 drops at night.

The dosage of the drug depends on the child’s weight

When calculating the dosage taking into account the child’s weight, also compare the daily amount with the allowable amount for a certain age. For children under 1 year old it is 30 drops, for children 1-3 years old – 45 drops, and for children over 3 years old – 60 drops. If the calculation results in a quantity greater than these figures, the dose is reduced and the child is given the drug at the maximum allowable dosage at his age.

Instructions for use

Required number drops are diluted with a small amount of non-hot liquid, and then given to the child. You can also give drops undiluted.
The drug is given every 8 hours.
Eating food does not affect the intake of Fenistil drops.
The drug cannot be heated, as it will lose its healing properties.

Download full instructions You can access the drug in the form of drops by following the link.

Features of use in infants up to one year

Fenistil is approved for use in infants over one month old. However, before using the medicine on an infant, you should definitely consult a pediatrician. Many doctors do not recommend giving such drops for up to a year, since they have a sedative effect and can cause respiratory arrest at night.

Fenistil is also applicable to children under one year of age, but the dosage will be slightly different

To give drops to your baby, you need to multiply the child's weight by 2, and then divide the resulting number into 3 doses. Having calculated a single dose for the child, the drops are mixed with the expressed human milk or a small amount of warm mixture. As a rule, infants do not protest against such medicine because it has a sweet aftertaste.

Overdose

If the dose of drops is exceeded, the child will experience this situation with increased temperature, increased heart rate, and dry mouth. Hallucinations and seizures may occur. Even if the dosage is exceeded once, you should consult a doctor, and if the baby accidentally drinks the entire contents of the bottle, you should not hesitate - immediately call an ambulance. Doctors will prescribe medications that will support the heart and respiratory system, and also quickly remove the drug from the baby’s body.

Komarovsky's opinion

Komarovsky emphasizes that Fenistil is classified as an antihistamine of the so-called first generation, which affects the functioning of the central nervous system. And that is precisely why such a drug has many side effects that are not observed with more modern antihistamines of the latest generation.

In addition, a well-known pediatrician focuses the attention of parents on the fact that Fenistil, like any other antihistamines, is designed to combat only the symptoms of allergies, but is unable to eliminate it completely, since it does not affect the cause. He advises focusing on identifying allergens and trying to eliminate their contact with the child's body.

For more information about this, see Dr. Komarovsky’s program.