home Analyzes What is cardiomagnyl (an antiplatelet drug)? Angioprotectors are also often used. Recommended. I took cardiomagnyl to thin the blood, everything returned to normal

What is cardiomagnyl (an antiplatelet drug)? Angioprotectors are also often used. Recommended. I took cardiomagnyl to thin the blood, everything returned to normal

Chimes on pharmaceutical market known for a long time. It is used as an antianginal (antiangina drug), antiplatelet (antithrombotic) and angioprotective (vascular protection) agent.

Curantil has a vasodilating effect mainly on small vessels hearts, but in large doses it reduces resistance in arterioles throughout the body and leads to a decrease in blood pressure. By expanding the diameter of the vessels, blood circulation increases and the flow of oxygen to the cells improves, therefore, the damaging effect of hypoxia or ischemia, which often occurs in heart disease, is neutralized. Curantil promotes the formation of collaterals (bypass paths) in ischemic areas, improves the functioning of the heart muscle, and reduces blood pressure.

Curantil improves microcirculation in the vessels of the brain, retina, and kidneys. During pregnancy, it slows down degenerative processes in the placenta, eliminates hypoxia of fetal tissue and restores placental blood circulation.

In addition, the drug prevents platelet aggregation and the formation of blood clots, especially when taken in combination with Curantil and acetylsalicylic acid. With an increase in a single dose of the drug, a shortening of the lifespan of platelets and a suppression of the tendency to thrombus formation are observed. This effect is used in the treatment of patients with deep vein thrombosis. The combined use of Curantyl and acetylsalicylic acid is quite often prescribed in the complex treatment of atherosclerosis, as well as to reduce the risk of developing a recurrent stroke in patients with ischemic stroke.

The main active ingredient of Curantil is dipyridamole, which helps increase the production of interferon, a protein with a pronounced antiviral effect. In this regard, Curantil can be used as a drug that increases the body's resistance to viral infections.

And the last area of application of Curantil is stress echocardiography and dipyridamole-thallium-201 perfusion scintigraphy in diagnostics coronary disease hearts in patients with unchanged coronary vessels. In this case, the drug is used as a diagnostic tool to determine the condition of the heart muscle, the safety of the valve apparatus and its contractile activity.

Release forms

Curantil is available in tablets, dragees and solutions for intravenous administration.

Pills yellow or greenish-yellow in color, covered with a shell. Each tablet contains 25, 50, 75 or 100 mg active substance dipyridamole. Depending on this, the drug is called Curantil 25, Curantil 50, Curantil 75 or Curantil 100.

Dragee contain 25 or 75 mg dipyridamole. Usually dragees are packaged in glass jars 100 pcs.

In ampoules A 0.5% dipyridamole solution is available. Each 2 ml ampoule contains 0.01 g of active substance.

Instructions for use of Curantyl

Indications for use

Curantil is prescribed to adults and children over 12 years of age who have vascular disorders in the brain, retina, heart, kidneys, deep vessels of the extremities. In obstetric practice, it is used for circulatory disorders in the placenta and deterioration of the fetal nutritional conditions.

The main indications for prescribing Curantil are:

Treatment of coronary heart disease, subacute myocardial infarction or post-infarction condition, stable angina, especially with intolerance to acetylsalicylic acid. For these diseases, Curantil can also be prescribed for prophylactic purposes.
Prevention of thromboembolism and thrombosis of arteries and veins in postoperative period when replacing heart valves.
Common atherosclerosis of heart vessels.
Heart failure in the compensation stage.
Hypertension II degree and higher.
Deterioration of placental circulation, fetal hypoxia, placental insufficiency.
Chronic failure cerebral circulation, cerebral infarction, discirculatory encephalopathy.
Included complex treatment for various microcirculatory disorders.
As an immunomodulatory drug (to enhance immunity) during periods of influenza and ARVI epidemics.

Contraindications

Any acute conditions caused by impaired microcirculation, unstable or decompensated diseases, as well as increased bleeding are contraindications for the use of Curantil.

The drug is not prescribed to children under 12 years of age, because there is not enough data on its harmlessness to the child’s body.

The drug is not prescribed for the following diseases or conditions:

Acute cerebral or myocardial infarction;
Acute or unstable course of angina;
Cardiac, renal, liver failure in the stage of decompensation;
Arterial hypotension, collapse, fainting;
Vegetative-vascular dystonia of the hypotonic type;
Violations heart rate - ventricular arrhythmias, atrial fibrillation etc.;
Obstructive diseases of the bronchopulmonary system;
Subvalvular (subaortic) aortic stenosis;
Common coronary sclerosis;
Tendency to spontaneous bleeding, presence of peptic ulcer (due to possible development bleeding), hemorrhagic diathesis;
Intolerance to any of the components of the drug.

Side effects

Side effects while taking Curantil occur quite rarely. Among them, the main place is occupied by dyspeptic symptoms - nausea, occasionally vomiting and diarrhea. Complaints of headache or muscle pain, weakness and dizziness may appear. People prone to arterial hypotension are likely to develop fainting and/or increase the heart rate to 90 or more times per minute.

In some cases, the phenomenon of cardiac “steal” occurs - retrograde movement of blood along the collaterals, bypassing the narrowed coronary vessels. Withdrawal syndrome may also develop with the development unstable angina or myocardial infarction. This phenomenon usually occurs when long-term treatment Chimes.

Extremely rare adverse reactions are urticaria and bronchospasm, as well as changes in the blood, in particular a decrease in the number of platelets (thrombocytopenia).

Unlike acetylsalicylic acid (aspirin), Curantil does not cause ulceration in the gastrointestinal tract.

Treatment with Curantil

The doctor selects the dosage and duration of taking Curantil individually, based on the form of the disease, the severity of its course and the patient’s sensitivity to the drug. If necessary, the drug can be taken long time, in some cases - up to 10 weeks or more.

Self-prescription of the drug is not allowed, due to the fact that its incorrect or unreasonable use can worsen the patient’s condition. Curantil is a prescription drug.

How to take Curantil?
The drug is taken before meals or 1.5-2 hours after meals. The tablet or pill should not be chewed; it must be swallowed with a sufficient amount of still water.

Curantil dosage
The maximum daily dose of the drug is 600 mg, it is prescribed only during the treatment of severe disorders. At simultaneous administration Curantil with anticoagulants or acetylsalicylic acid, the dose of Curantil is halved.

Depending on the nature of the disease, Curantil can be prescribed in the following dosages:
1. For coronary heart disease, the initial daily dose of the drug is 225 mg. The dose is divided into 3 doses.
2. For cerebrovascular accidents, Curantil is prescribed 75 mg 3 to 6 times a day.
3. As an antiplatelet agent, Curantil is prescribed 3-6 tablets per day, dividing the dose into several doses. If necessary, the daily dose can be increased to 8-9 tablets.
4. During an epidemic of influenza and ARVI, Curantil is taken 1-2 tablets once a week for 1.5 months. To increase immunity in frequently ill people, the drug is prescribed at a dose of 100 mg per week (the dose is taken in 2 doses, the interval between doses is 2 hours) for a period of up to 8-10 weeks.

Chimes during pregnancy

Curantil can be taken during pregnancy; it does not have a negative effect on the fetus. However, in the 2nd and 3rd trimesters it should be taken with extreme caution and if there are clear indications for this.

Most often, Curantil is prescribed to pregnant women for placental insufficiency, late toxicosis, concomitant cardiovascular and renal pathology, premature aging of the placenta, post-term pregnancy.

Curantil can also be used to increase nonspecific immunity in pregnant women during dangerous periods. viral diseases periods or when frequent exacerbations existing chronic viral infection(eg genital herpes).

Interaction of Curantyl with other drugs

During treatment with Curantil, it is not advisable to drink drinks containing caffeine (coffee, cocoa, tea, mate, Coca-Cola, Pepsi-Cola), as well as take the drug diuretin. These substances can significantly reduce or completely neutralize positive effects Chimes.

At simultaneous treatment Curantil and indirect anticoagulants (drugs that reduce blood clotting), as well as acetylsalicylic acid, the dose of Curantil should be reduced, because its activity increases sharply and there is a risk of spontaneous bleeding.

Curantil may enhance the effect of drugs prescribed to lower blood pressure. And, on the contrary, when using Curantil and drugs for the treatment of Alzheimer's disease, dementia, myasthenia gravis, a decrease in the activity of the latter is observed.

The simultaneous use of Curantil and cephalosporin antibiotics (Cefamandol, Cefoperazone, Cefotetan) leads to an increase in the antiplatelet properties of Curantil.

Antacids used for elevated acid-forming function stomach, reduce the absorption of Curantil, which causes a decrease in the therapeutic effect.

It is not allowed to mix Curantil solution for intravenous injections with others injectable drugs due to the fact that an insoluble precipitate may form. You cannot mix Curantyl solution with Actovegin, because the latter can cause anaphylaxis. However, tablet forms of Curantil and Actovegin are often prescribed in the complex treatment of microcirculatory disorders of various origins.

Curantil's analogs

Curantil has quite a lot of analogues. Depending on the country and manufacturer, the drug is produced under the following trade names:

During pregnancy, the percentage of development is high various pathologies and diseases of the expectant mother and fetus.

It is necessary to strictly follow doctor's instructions to avoid problems.

Impaired blood circulation can lead to, which can lead to negative consequences.

One of effective drugs prescribed during pregnancy are Curantil tablets.

Curantil is an angioprotective drug. Main active component The medication is dipyridamole. This remedy helps dilate blood vessels, thin the blood and improve capillary circulation.

Doctors often prescribe Curantil during pregnancy to prevent the formation of blood clots.

It ensures the penetration of adenosine into the intracellular space and increases its concentration in plasma.

Adenosine has a positive effect on the smooth muscles of blood vessels and strengthens them.

Curantil has a mild vasodilating effect and is an indicator of the synthesis of a substance such as interferon.

Increasing the production of interferon in the human body leads to increased immunity and improves the body's resistance to colds.

Curantil is indicated during pregnancy in the following cases:

The drug is also prescribed for the prevention of blood clots, stent occlusion and for the complex treatment of glomerulonephritis.

General contraindications:

acute myocardial infarction;
atherosclerosis;
obvious renal failure;
possible allergic reactions on the ingredients.

Prescription of Curantil in early and late pregnancy

During the period of gestation, doctors prescribe several courses of Curantil. In some cases, it is taken continuously without interruption.

Throughout pregnancy, Curantil is used to normalize blood supply to the placenta.

This is of fundamental importance, since the baby will not be able to receive normal amount substances necessary for its development, with impaired blood circulation. As a result, oxygen starvation may begin.

To support the placenta, the method of administration is as follows: Curantil is taken in a dosage of 75-225 mg/day. The exact dosage is prescribed by the doctor.

In the first trimester, Curantil can be used to treat ARVI and other infectious diseases. Viral diseases can cause significant harm to a child, so do not delay visiting a doctor.

For the prevention of ARVI, Curantil is prescribed in a dosage of 50 mg once a week. For the same reason, Curantil is sometimes prescribed during pregnancy planning.

On early stages During pregnancy, the child does not have independent protection in the form of the placental membrane. He is especially at risk. If viruses penetrate the embryo, the result may be termination of pregnancy. In this case, Curantil is also necessary to prevent the development of intrauterine pathology.

In the early stages of pregnancy, you should drink Curantil 50 mg (usually 2 tablets) twice a day, with a break of 2 hours.

On later pregnancy Curantil is prescribed for.

Circulatory disorders, edema, excess weight and kidney problems are the main reasons for the development of late toxicosis. All this leads to an increase in platelets in the blood.

Vascular spasms may occur due to blood thickening. As a result necessary substances and oxygen practically does not reach the most functional internal organs. In this case, the daily dose of Curantil can be increased to 600 mg.

Curantil makes the blood more fluid and improves its microcirculation.

As a result, the tone of the capillaries gradually stabilizes. For the same reason, Curantil is prescribed for.

We can highlight the main types of positive effects of Curantil at 35-38 weeks of pregnancy:

prevention oxygen starvation the developing baby's brain.
Providing nutrients.
Fight with.
Preventing mental retardation.
improves the condition of the mother's organs, removes swelling.
Maintains stable blood supply to the placenta and prevents abruption from occurring.
Prevents the development of preeclampsia in pregnant women.

The above drug can be prescribed by a doctor and in for preventive purposes during pregnancy.

No need to take independent decisions about acceptance or cancellation of appointment medicine. In this regard, it is better to consult a medical specialist.

Main contraindications to taking Curantyl

When prescribing, the doctor must take into account the specifics of the pregnant woman’s condition and existing contraindications.

These include:

lack of platelets and decreased blood clotting;
stomach ulcer or duodenum;
or ;
diseases of internal organs;
heart rhythm disturbances.

When using Curantil, side effects may occur such as:

general weakness of the body and lungs
dizziness,
increased heart rate

You should pay attention to whether it appears on the body skin rash. Even with minor rashes, you should consult a doctor.

It may be necessary to reduce the dosage of Curantil. In general, a pregnant woman’s body tolerates taking the medicine normally.

Doctors categorically prohibit taking Curantil during pregnancy along with coffee and strong tea, as they reduce it positive action. Do not combine the drug with aspirin and other medications.

Personal experience
I was prescribed Curantil twice - during my first and second pregnancy. Then I just came to the antenatal clinic and went through routine inspection. In both cases, it was prescribed to me at 4-5 months of pregnancy.

After meeting with my gynecologist, I ran to the pharmacy and bought the drug. At home, of course, I read a lot of reviews. It is usually prescribed to pregnant women who may develop varicose veins. But most often it is prescribed for prevention.

After reading the reviews, I thought for a long time whether I should drink it. Many have written that Curantil is prescribed if there is swelling and problems with the placenta. On the ultrasound I was fine. Friends said that the drug improves immunity well. Well, I started taking it according to the prescription.

During my first pregnancy, I was prescribed Curantil 50 mg three times a day. Sometimes, I admit, I skipped appointments and forgot to drink at the time. One jar lasted me about 3-4 weeks. The drug was not very affordable, so I took it during my first pregnancy until 8 months, and during my second pregnancy until 7 months. I stopped taking it because I didn’t notice any significant changes in my tests or my body.

The family doctor said that the baby was too active in the womb (in the second pregnancy), and this indicates a lack of oxygen. And if you drink Curantil, the nutrition of the placenta will be more effective, since the blood is thinned. Of course, to avoid repeat miscarriages, I took the pills for a while. Previously, there was a strong tone of the uterus, but then it didn’t even remind me of itself.

During my third and fourth pregnancies, I did not take anything. The new gynecologist said that such strong drugs not prescribed for prophylaxis. The only thing that happened after starting the course was frequent fainting. Maybe the heat and stuffiness also played a role, although this was not observed in the next two pregnancies.

If we compare the pregnancy and all the tests when I took and did not take Curantil, I can say that there is no difference. Ultrasound readings were always normal, but I felt only bad - weakness, nausea, fainting. In general, in order not to take medications in vain, you need to see at least two or three gynecologists, who will objectively tell you whether you need treatment or not. I just wouldn’t recommend such powerful drugs for prevention.

Tatiana, 29.

What can be replaced?

Curantil is an angioprotective or vascular protecting drug. It is possible to take similar medications if individual intolerance to its components is identified.

Considered the most effective analogue Chimes. It improves microcirculation of capillaries and reduces venous stagnation.

Its use contributes to significant activation of blood supply.

Phlebodia has a minimal number of side effects. But clinically the drug is not so well studied that it can be used in the first trimester of pregnancy. It is prescribed at 12-14 weeks of pregnancy.

Cardiomagnyl.

Pregnant women are also allowed to take it. It is an excellent blood thinner, but does not have a positive effect on the immune system.

In some cases it is prescribed joint reception Cardiomagnyl and Curantyl to achieve maximum therapeutic effect.

Actovegin.

A biostimulating agent that helps activate metabolic metabolism.

It effectively eliminates the phenomena of hypoxia. Can act as an analogue of Curantil.

But unlike it, it has strongly pronounced side effects. It's about about urticaria, excessive sweating, itchy dermatoses. It is allowed to administer the product by injection.

Hofitol.

Medicine for plant based, which can be prescribed to remove toxins from the body and improve fat metabolism.

It will not be possible to replace Curantil with it. But doctors often prescribe pregnant women to take these drugs together for the complex treatment of preeclamptic condition.

The decision to replace one drug with another can only be made by a medical specialist.

Release forms

The medicine is available in the form of dragees and tablets with different dipyridamole contents - 25 and 75 mg.

Thereby safe means, you can strengthen your immune system and eliminate premature birth because of .

There are also similar drugs, but they have more pronounced side effects. The dosage should be prescribed by a doctor.

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Curantil, instructions for use of the drug, indications for use, how it affects platelets and blood microcirculation. At what pressure to take pills, what help for varicose veins. All detailed information in our article. We will be grateful for your feedback or repost on social networks.

What is Curantil n used for: antiplatelet agent and immunomodulator

Many people have encountered a drug like Curantil N. This tool can be attributed to pharmacological group anti-renegades, .

Therefore the drug is different wide range actions.

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How it affects health: on platelets and blood microcirculation

Reduces platelets, making the blood thin. Therefore, it must be taken with caution. Sometimes nosebleeds are possible, which indicates the need to discontinue the drug.

Renders positive impact for microcirculation.

Manufacturer

This medicine is produced in Germany. This confirms the high quality drug.

Release form

The drug is available in three forms:

tablets - distinguished by a yellow tint, contain 25, 50, 75, 100 mg of the main substance;
dragees - the dosage of dipyridamole in them is 25 or 75 mg, packaged in dark glass jars;
ampoules - used for intravenous administration and contain 0.01 g of dipyridamole.

Composition of the medicine

The drug contains Dipyridamole. This substance improves microcirculation, prevents hypoxia and reduces blood pressure. In addition, it has additional components, the composition of which depends on the form of release of the drug.

pharmachologic effect

This product provides angioprotective, immunomodulatory and antiaggregation effects.

Mode of application

Indications for use

It is a medicinal product whose indications for use are:

ischemia;
prevention of vein thrombosis;
post-infarction state;
heart failure during the compensation period;
problems with blood circulation in the placenta;
placental insufficiency;
hypertension from 2 degrees;
fetal hypoxia;
problems with cerebral circulation; cerebral infarction;
reduced immunity, with ARVI.

Indications are described in detail in the instructions for use of the drug.

Contraindications

Curantil is a drug that has a number of contraindications. IN annotations the following list is provided:

Heart attack in the acute stage.
Children's age up to 12 years.
Hypotension.
Heart failure.
Kidney failure.
Arrhythmia.
Stomach ulcer.
Diseases of the lungs and bronchi.
Coronasclerosis.
Individual intolerance to active substances.

Side effects

This remedy is well tolerated. Occasionally, such side effects may be associated with disturbances in the functioning of the digestive system, headache or muscle pain. Fainting is possible with low blood pressure.

Rarely disrupts blood flow. Sometimes urticaria and bronchospasm are noted.

Course of treatment of tablets

The course of treatment is selected depending on the characteristics of the disease. The duration of therapy is up to 10 weeks. It is allowed to start taking the drug only after consulting a doctor.

How to take is indicated in official instructions.

Who is prescribed the medicine?

Curantil is prescribed for men and women. The drug is prescribed for aging placenta, low placentation, oligohydramnios, and for the endometrium.

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I attribute it to varicose veins, thrombophlebitis and other problems with veins and blood flow.

At what pressure should I take it?

This remedy reduces blood pressure. Prescribed to people with hypertension. If your blood pressure is low, this medication may cause fainting.

Dosage during pregnancy for women

Curantil is one of the drugs prescribed during pregnancy. It has been proven that this remedy does not affect the fetus harmful effects. Even while planning this medicine appointed jointly with hormonal drugs. and improves microcirculation.

During pregnancy, indications for the use of the drug are: placental insufficiency, kidney problems (with glomerulonephritis, with pyelonephritis), aging of the placenta, late toxicosis.

The drug is prescribed as an immunomodulator.

In late pregnancy, you should drink with caution and only as directed by your doctor.
Only an obstetrician-gynecologist can tell you how to drink during pregnancy. The dosage is determined based on the woman’s condition. Daily dose of the active substance should not exceed 225 mg in 5 doses. How to take it before or after meals is also of interest to women. It is recommended to drink before meals or an hour after meals.

In the early stages of pregnancy, this remedy helps to normalize the blood supply to the placenta, and therefore improve the nutrition of the unborn child. In addition, the drug is effective against colds, or rather for preventing them, which is important in the first trimester of pregnancy.

Analogs

Whether Curantil is an anticoagulant or not is a concern for pregnant women and those who need an analogue of the drug. This remedy helps thin the blood.

Best before date

Tablets are valid for 3 years, and dragees for 5 years.

Alcohol compatibility

Some people are interested in the compatibility of this product with alcohol. There is no information about such a combination in the official instructions.

The active substance of the drug does not react to ethanol.

It is possible that alcoholic drinks may cause side effects. Doctors note that you can only drink a glass of alcohol without consequences.

Curantil: instructions for use 25 mg and 75 mg 100 tablets

Price: where to buy in Moscow and cost in other cities

How much Curantil costs is important to know for people who need regular use of the drug.

It is worth checking out the prices in cities for the drug in a dosage of 25 mg:

You can buy this medicine in Moscow for 642 rubles.
You can buy the product in St. Petersburg for 615 rubles.
The price in Lipetsk for the same packaging is 590 rubles.
In Samara - 605 rubles.
Price in Tambov - 580 rubles.
In Sochi it sells for - 610 rubles.
In Stavropol, 120 tablets cost 590 rubles.
In Orenburg - 596 rubles.
Price in Krasnodar - 610 rubles.
In Chelyabinsk - 611 rubles.
In Belgorod - 598 rubles.
Price in Omsk - 607 rubles.
Price in Tula - 591 rubles.
In Voronezh - 575 rubles.
In Kostroma - 610 rubles.
In Rostov-on-Don - 597 rubles.
In Perm - 600 rubles.
In Bryansk - 620 rubles.
In Cheboksary - 602 rubles.

Thus, the average price in Russia is 600 rubles. The price in Kazakhstan for 120 tablets of 25 mg is 1840 tenge. Curantil N is also represented in Ukraine. The price of this medicine there is 618 UAH.

Cheap analogues in tablets, injections

Not all people can afford to buy the drug. In this case, it will not be possible to do without substitutes, some of these analogues Russian production. To get a positive effect, the doctor selects another antiplatelet agent.

Some of the popular ones are:

The listed funds have their own characteristics. Some drugs are not suitable for pregnancy. Others are better to drink for prostatitis or before childbirth.

Therefore, before starting a course of treatment, you need to consult a doctor.

Mydocalm

Mydocalm is a drug that helps cope with muscle spasm. This remedy can also be used for hematomas and injuries. Mydocalm is available in the form of tablets and ampoules.

Cardiomagnyl is an antiplatelet agent based on acetylsalicylic acid. This remedy helps with thrombosis, varicose veins of the lower extremities, and the risk of heart attack. Drinking Cardiomagnyl is recommended for prevention in old age.

(included in Cardiomagnyl )

B Acetylsalicylic acid + Magnesium hydroxide (text from instructions)⇒ Dipyridamole (he was found)

When used simultaneously, acetylsalicylic acid enhances the effect of the following drugs:
- methotrexate - by reducing renal clearance and displacing it from protein binding, the combination of acetylsalicylic acid with methotrexate is accompanied by an increased incidence of side effects from the hematopoietic organs;
- narcotic analgesics, other NSAIDs;
- heparin and indirect anticoagulants - due to disruption of platelet function and displacement of indirect anticoagulants from connection with blood plasma proteins;
- thrombolytic, antiplatelet and anticoagulant drugs (for example, ticlopidine);
- digoxin - due to a decrease in its renal excretion;
- hypoglycemic drugs for oral administration (sulfonylurea derivatives) and insulin - due to the hypoglycemic properties of acetylsalicylic acid itself in high doses and displacement of sulfonylurea derivatives from communication with blood plasma proteins;
- valproic acid - by displacing it from its connection with blood plasma proteins.
The simultaneous use of acetylsalicylic acid with ibuprofen leads to a decrease in the cardioprotective effects of acetylsalicylic acid.
The combination of acetylsalicylic acid with anticoagulants, thrombolytics and antiplatelet agents is accompanied by increased risk development of bleeding.
Simultaneous administration with acetylsalicylic acid increases the concentration of barbiturates and lithium salts in the blood plasma.
By enhancing the elimination of salicylates, systemic corticosteroids weaken their effect.
GCS, ethanol and ethanol-containing drugs enhance negative impact on the gastrointestinal mucosa and increase the risk of gastrointestinal bleeding.
When taking acetylsalicylic acid with ethanol, there is an increase in toxic effect ethanol on the central nervous system.
Acetylsalicylic acid weakens the effect of uricosuric drugs - benzbromarone, probenecid (reduced uricosuric effect due to competitive suppression of renal tubular excretion uric acid), ACE inhibitors(a dose-dependent decrease in GFR is noted as a result of inhibition of PGs, which have a vasodilatory effect, and, accordingly, a weakening hypotensive effect), diuretics (with joint use with acetylsalicylic acid in high doses, a decrease in GFR is observed as a result of decreased PG synthesis in the kidneys).
Antacids and cholestyramine reduce the absorption of acetylsalicylic acid.

Interactions Dipyridamole (included in Kurantil ) ⇔ Magnesium hydroxide (included in Cardiomagnyl )

B Dipyridamole (text from instructions)⇒ Magnesium hydroxide (he was found)

Interactions Dipyridamole (included in Kurantil ) ⇔ Acetylsalicylic acid (included in Cardiomagnyl )

B Dipyridamole (text from instructions)⇒ Acetylsalicylic acid (he was found)

Antacids reduce the Cmax of dipyridamole due to decreased absorption. Acetylsalicylic acid and indirect anticoagulants enhance the effect, heparin increases the risk of developing hemorrhagic complications. When combined with clopidogrel, the risk of bleeding increases. When used concomitantly with fludarabine, the effects of fludarabine may be reduced. Dipyridamole increases the plasma concentration and cardiovascular effects of adenosine. Dipyridamole may interfere with the anticholinesterase effect of cholinesterase inhibitors, and therefore may potentially worsen the course of myasthenia gravis. Do not mix dipyridamole with other drugs in the same syringe (precipitation may occur).

Common interactions between dipyridamole and acetylsalicylic acid

Dipyridamole and Acetylsalicylic acid belong to the same pharmaceutical group:

Blood function is very important in human body, because it contains cells that are able to protect the body. If the blood begins to thicken, doctors prescribe blood thinners.

Let's look at the reasons for this phenomenon and provide a list of pills and medications that will help correct the situation.

Causes of blood thickening

Consumption of low quality food and water;
Diseases of the spleen;
The body is clogged with toxins (usually observed in patients over 50 years old);
Lack of enzymes to break down nutrients;
Dehydration, long stay in the sun;
Excessive physical activity;
Living in an unfavorable climate.

These factors affect the quality and thickness of blood. Early manifestations pathologies are drowsiness, fatigue, irritability, memory loss, depression.

Diseases that cause blood viscosity:

Varicose veins;
Heartbreak;
Atherosclerosis;
Brain hemorrhage.

In the absence of compensatory treatment, all this can lead to the formation of blood clots, so patients are advised to use tablets to thin the blood and prevent blood clots.

Treatment options

Thick blood can be thinned with medication, folk remedies, therapeutic nutrition, leeches and other methods. To enhance the effect, these methods are combined.

If you have a predisposition to this disorder, you will need regular prevention and monitoring your health.

Medication

Most effective method treatment - appointment medicines. Blood thinners The products help prevent the formation of blood clots and improve the condition and quality of blood.

Each medicine is effective and good in its own way, but only a specialist has the right to prescribe a specific drug to a patient. At the very least, self-medication will not give results and can lead to complications.

List of blood thinning drugs:

Titles	Properties	Average price, rub.
Heparin	Prevents blood thickening. The composition of the product includes a thinning substance contained in the saliva of leeches. Heparin is prescribed by a doctor in a dosage that is selected individually for each patient.	550
Warfarin	An anticoagulant drug that reduces blood clotting. Thinning with Warfarin tablets is used if there is a risk of blood clots. Sold without a prescription.	160
Chimes	Reduces blood thickness and is used to prevent blood clots in varicose veins and atherosclerosis.	700
Dabigatran	Analogue of Warfarin.	from 680
Aspecard	Tablets that strengthen the walls of blood vessels with an antithrombic effect. Contains aspirin.	It is not sold in the Russian Federation, in Ukraine it costs 32 UAH.
Aescusan	A medicine that thins the blood and increases the elasticity of blood vessels. Normalizes the blood circulation process.	250
Cardiomagnyl	A popular remedy that prevents blood clotting and restores the human body as a whole. Aspirin in the product affects the condition of the blood, and magnesium reduces the effect of the main substance on the stomach. Prescribed by a doctor, prohibited for self-medication.	from 130
Preparations with zinc and lecithin	They prevent the formation of blood clots, increase the absorption of water in the body, thereby normalizing the composition of the blood.	Depends on the manufacturer
Vitamins	Improves vascular health, promotes their restoration, and reduces the risk of thrombosis.	Depends on the manufacturer

Each medication has its own instructions for use, so before drink drug, first of all you should read the instructions for its use.

There are still medicines, which are not only liquefy blood, but also have additional effects. However, to achieve optimal results from their use, they must be combined with basic drugs.

These include:

Phlebodia;
Sermion;
Mexidol;
Diacarb.

Angioprotectors are also often used. Recommended:

Diosmin;
Hesperidin;
Actovegin;
Angiovitis;
Troxevasin (or its analogue Troxerutin);
Detralex;
Omega 3;
Venarus.

Products that do not contain aspirin

Besides aspirin There are medications that will help solve the problem.

So, names of tablets which thin the blood without acetylsalicylic acid:

What means do you need accept And how to dilute with medications thick blood, the attending physician has the right to decide. To avoid adverse consequences and side effects, independent selection of drugs is not allowed.

How to replace Cardiomagnyl?

On the pharmaceutical market there is a list of drugs that are analogues and substitutes for Cardiomagnyl, these are:

Each drug has its own contraindications and side effects, so before you start taking it, you should consult a specialist.

Which is better – Curantil or Trombo ACC?

Both drugs are most often prescribed during pregnancy; they are analogues in relation to each other.

Curantil is prescribed to improve blood circulation, starting from the 2nd trimester of pregnancy. Before pregnancy, when planning, use Thrombo ACC.

The reason for prescribing these drugs may be hereditary thrombophilia or indications of blood tests (coagulogram, etc.), by which a hematologist or gynecologist determines the risk of blood clots in a pregnant woman.

In this case, the drugs can be prescribed simultaneously.

Thrombo Ass contains acetylsalicylic acid and costs from 40 rubles, and Curantil is Dipyridamole, and its price in pharmacies is from 520 rubles. The difference in cost, as you can see, is quite large. So if you need budgetary means– it’s better to choose Trombo ACC.

Which one is better is decided strictly individually for each patient, depending on the purpose of treatment and indications.

Food

The diet helps to achieve positive dynamics while reducing blood clotting. There are products that make it thicker, others, on the contrary, thin it out.

Kefir and yogurt from cow's milk;

Dietary meats – chicken breasts, turkey (without skin and fat).

Patients need to drink more fluids - water reduces blood viscosity and improves absorption nutrients. An adult needs to drink about 2 liters per day clean water without gas.

It is also useful to drink herbal and fruit teas (ginger, strawberry, raspberry, cranberry, green) and juices from fresh vegetables and fruits.

Video

Increase thickness	Liquefy
Food of animal origin, except dairy products	Fresh berries and fruits
Roast	Flaxseed and olive oil
Smoked	Vegetables
Protein food	Ginger
Carbohydrate foods, especially those high in sugar	Sunflower seeds, almonds and walnuts
Alcohol	Onion garlic
Sweet and carbonated drinks	Products rich in magnesium (for example, rolled oats, etc.)