Actovegin: ointment for topical use. Actovegin eye gel

Actovegin is an ophthalmic gel that is used both in ophthalmology and for diseases of other organs; in particular, the substance is used to reduce the risk of diseases of the intestines and its tract. After application to the skin, the gel does not penetrate into the blood. In this way, you can avoid an overdose and maintain the concentration of the drug in the body in the right amount for a long time.

This drug is produced in different forms- injection solutions, ointments or gel. But it is the gel that is currently most popular.

The product has a viscous consistency, but at the same time retains its shape well. Its advantages:

• spreads over the skin in a thin layer and is quickly absorbed;
• can be used in conjunction with other drugs and suspensions;
• has similar acidity to leather.

This tool can be used:

• for preparation for skin grafting operations;
• in the treatment of mucous membranes;
• for burns.

The product quickly heals wounds. Refers to antihypoxatins.

Main active component acts as a hemoderivative of the blood of calves. There are also excipients:

• propylene glycol;
• carmellose sodium;
• calcium lactate;
• propyl parahydroxybenzonate;
• purified water;
• methyl parahydroxybenzonate.

The gel can only be used externally. It has no color. Packaged in aluminum tubes. Each tube contains from 20 to 50 grams of gel. All this is packed in cardboard boxes, which also contain instructions for use.

The drug does not contain toxins, but contains amino acids, peptides and others useful material for a person. The release form makes it possible to speed up wound healing and regulate metabolic processes in the body. When using this drug, cell resistance to hypoxia develops.

Impact

This substance can activate the metabolism of glucose and oxygen. After contact with a skin area, it stimulates wound healing.

Indications

Since the drug cleanses skin areas from infections, it is usually used in the treatment of deep wounds or ulcers.

The substance is also effective for skin lesions chemicals, ultraviolet rays, hot water or steam, after exposure to radiation.

At complex therapy used to prevent the appearance and treatment of bedsores or ulcers.

This drug can also be used in the following cases:

• inflammation of the cornea;
• irritation after wearing lenses for a long time;
• eye lesions.

Instructions

1. The substance is applied in a thin layer.
2. When treating ulcers, you need to apply a thick layer or make compresses with Actovegin. The dressing should be changed 1-2 times during the day or as needed.
3. For inflammation and irritation of the eyes, apply a small amount of the product to the affected area. The number of procedures per day is 2-3. The duration of the course of treatment is determined by the doctor. Everything will depend on the complexity of the disease.
4. After use, the tube should be stored in a dark place at room temperature for 30 days.

Contraindications

This remedy should not be used if the body does not tolerate some of its components. The possibility of using the substance during pregnancy and lactation is determined by the doctor.

Adverse reactions

After prescription, the drug must be used according to the instructions. It is usually well tolerated and does not cause negative side effects. side effects.

On initial stage reception may appear discomfort on the area of ​​skin where the gel is applied, or allergies. But this should not be a reason to refuse to use the product. If such symptoms become permanent and the gel does not bring the expected effect, then use should be stopped and consult a doctor, who will review the therapy.

Skin allergy - possible side effect

Storage

The shelf life is three years. After its completion, it is not recommended to use the gel.

Analogs

WITH Preservation of vision until old age - one of the conditions of our active work . We do not always think about the importance of the organ of vision in our lives. I think that each of us will agree that the greatest joy in a person’s life is the opportunity to see people close and dear to us. It is the eyes, first of all, that give us the opportunity to choose a specialty. With the help of the organs of vision we receive most information about the world around us. The human brain receives basic information through our eyes. So it is impossible to overestimate the role of the organs of vision in our lives. For centuries, poets have praised the eyes in their works, and physicists have tried to imitate the eyes (as the best example of optical instruments).

In a word, you need to protect your eyes! Equally important for preserving vision is timely consultation with a doctor for help with the slightest problems with vision. Few people manage to avoid certain eye problems throughout their lives.
Let's stop now on indications for use Actovegin eye gel.

Numerous possible eye problems include damage to the cornea and sclera of the eye:

ulcers cornea of various origins;

burns corneas with substances such as lime, alkali or acid;
keratitis (as a result of flu, tuberculosis; herpetic or fungal keratitis, etc.). It could be inflammation resulting from a corneal transplant ( transplantation ) or for other reasons;

Scuffs corneas as a result of use contact lenses .

Great help in situations like this twenty percent eye gel(jelly) Actovegin.

The use of Actovegin eye gel and for preventive purposes:
when atrophic and dystrophic processes in the cornea during the selection of contact lenses .

The gel is also used With for preventive purposes radiation injuries corneas and for cornea treatment after sessions radiation therapy (in oncology).

Treatment with this popular gel has worked well in all of the above cases.

Colorless transparent 20% eye gel Actovegin is produced (by the Austrian company Nycomed) in tubes of 5 g. The color of this gel may be slightly yellowish transparent. These five grams of gel contain forty milligrams of dry weight of deproteinized hemoderivate from the blood of calves, as well as 0.25 mg of the preservative thiomersal, sodium carboxymethylcellulose, sorbitol and lactic acid. We have already written in detail about the properties of Actovegin.

How to use Actovegin 20% eye gel?

One or two drops of gel are squeezed into the affected eye. The doctor prescribes how many times a day this procedure should be performed (from one to three times). The duration of treatment is also determined by the ophthalmologist (it depends on your diagnosis, current condition and existing contraindications).

Contraindication Individual hypersensitivity may occur when using Actovegin eye gel.

Pregnant can use 20% Actovegin eye gel on a general basis: no cases have been registered negative impact on the woman and the fetus. During lactation, treatment with this gel is also allowed.

Possible side effects: lacrimation, scleral injection (" Red eyes) .

Storage conditions:

After opening a tube of Actovegin eye gel, you can only use it for four weeks.

Shelf life of the drug: three years, and the sealed tube of gel should be stored at room temperature (up to+ 25° ) in a dark place and out of reach of children to the gel.

We would like to give an example of one of the studies of Actovegin eye gel.

ABOUT clinical trial two eye gels - Actovegin and Korneregel - on patients after surgery with a corneal incision, the doctor Kirisenko L. I. and co-authors write in the article „ Comparative assessment of the use of Korneregel and Actovegin eye gel in patients after cataract extraction ”(RMJ, N. 178) next : after treatment with Korneregel eye gel, corneal edema disappeared on the fourth or fifth day, and epithelization of the incision was recorded already on the third or fourth day. The active substance of Korneregel is dexpanthenol. This eye gel is produced by a 5% company (Bausch a. Lomb/ USA), founded in 1853.
When patients were treated with Actovegin eye gel, the swelling disappeared on the sixth day, and epithelization of the incision occurred on the fifth or sixth day.

As for patients on whom none of the above-mentioned medications were used, the following was observed: : epithelization of the cornea was much slower than with the use of these eye gels.

In conclusion, I would also like to mention Solko eye gel With Eril.
As is known, Solcoserylis an analogue of Actovegin.
Solcoseryl eye gel (jelly) has similar indications for use as Actovegin eye gel. However, you cannot replace Actovegin eye gel with it yourself. Only a doctor can replace one medication with another so that the benefits of treatment are maximized and there is no harm.

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Actovegin activates metabolism, improves trophism and stimulates regeneration. In ophthalmology it is used to treat burns, ulcerative defects cornea, keratitis, as well as for the prevention of radiation damage to the cornea of ​​the eye.

Composition and release form

Actovegin contains a deproteinized hemoderivat, which is obtained from calf blood. The drug is produced in several dosage forms:

• Dragee forte 200 mg;
• Solution for injection (40 mg in 1 ml);
• Solution for infusion with glucose (1 g in 250 ml);
• Solution for infusion with sodium chloride (1 or 2 g in 250 ml);
• Eye gel (200 mcg per 1 g);
• Gel (200 mg in 1 g);
• Cream (50 mg per 1 g);
• Ointment (50 mg per 1 g).

In ophthalmology, eye gel is used. It has a uniform structure, colorless or yellowish, transparent. 5 mg of the drug is placed in an aluminum tube.

The package of eye gel contains 8 mg of dry deproteinized mass obtained from the blood of calves. Auxiliary components include sorbitol, carboxymethylcellulose, thiomersal, lactic acid.

pharmachologic effect

Autovegin activates metabolic processes in the body, improves tissue nutrition and stimulates regenerative processes.

The active substance of the drug is a hemoderivat from calf blood, which consists of nucleic acids and low molecular weight peptides. Actovegin increases the accumulation and transport of glucose, oxygen and other nutrients. All this helps to increase the rate of ATP metabolism, as a result of which the cell’s energy resource increases.

A secondary effect of Actovegin is considered to be an increase in blood supply in the area of ​​influence of the drug. When administered parenterally, the medicine begins to act within half an hour, and when administered enterally, after three hours.

Indications

IN ophthalmological practice Actovegin is used for corneal burns caused by chemicals (acid, lime, alkali), corneal ulcers, keratitis, including inflammation after corneal flap transplantation, and defects in the corneal epithelium resulting from the use of contact lenses. Actovegin is also used in the selection of contact lenses for patients with atrophy or dystrophy of corneal cells.

In addition to ophthalmology, the drug Actovegin is also used in other branches of medicine to improve blood supply and nutrition to the brain, accelerate wound healing, treat ischemia, hypoxia, etc.

Mode of application

Actovegin can be used in different doses, which are determined by the specific nosology of the disease and the severity of its course.

Dragees are prescribed 1-2 times a day before meals.

At intramuscular injection the initial dose is 10-20 ml, which is then reduced to 5 ml per day. At intravenous administration Actovegin is administered dropwise in a 250 ml solution every day or several times a week. The duration of the course is 10-20 days.

Local forms of Actovegin (gel, cream, ointment) are applied directly to the wound surface in a thin layer. The frequency of application is 2-3 times a day. When using an eye gel, 1-2 drops of medication are squeezed onto the surface of the eye directly from the tube. The duration of treatment is determined by the doctor.

Contraindications

Actovegin should not be prescribed to patients with hypersensitivity to the components of the drug.

Data about negative impact Actovegin was not received for the fetus or mother, therefore, when potential benefits can be used in this category of patients. It is not advisable to use Actovegin during lactation.

Side effects

When using Actovegin, you may develop allergic reactions in the form of urticaria, increased body temperature, a feeling of a rush of blood. TO local reactions include lacrimation, burning, scleral injection, itching.

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Actovegin ointment is used as medicinal substance to eliminate trophic processes in the human body. The drug can be used to cure various diseases, including the organs of vision.

Compound

Actovegin ointment is available in tubes ranging from 20 to 100 grams. They are packed in carton boxes, which also contains instructions for use. The main active ingredient is hemoderivat from the blood of calves. One hundred grams of the product contains about 5 milliliters. It also contains auxiliary components:

• propyl parahydroxybenzoate - this substance can be found in plants or in certain types insects, can have a strong antimicrobial effect and inhibit the growth of bacteria or fungi;
• methyl parahydroxybenzoate - helps prevent the development of bacteria and can have a disinfecting effect, the substance is not dangerous to humans and is independently eliminated from the body;
• peptides and amino acids - belong to physiological compounds and are not dangerous to the body.
• cetyl alcohol - protects the code from microbes and ultraviolet radiation;
• paraffin - has a dermatoprotective effect, protects the skin, softens it and makes the healing process faster;
• water.

This ointment has no analogues or contraindications for use. The product can have a beneficial effect on the body and accelerate metabolic processes in it.

Despite the fact that the drug does not have negative influence, it is recommended to start using it only after consulting a doctor.

The substance belongs to such drugs that can affect the body at the cellular level. The ointment is able to activate the transport function, resulting in the accumulation of oxygen and glucose in the tissues. Therefore, metabolism accelerates and the ability of cells to regenerate increases.

Action

The ointment is an antihypoxane. When the metabolic process is disrupted or increased energy consumption occurs, the substance stimulates and brings all functions back to normal. The ointment is well absorbed by cells.

Usually the product is used topically for external use. After use positive effect can be noticed within 10-15 minutes. It can work for 2-3 hours.

So, let's figure out why the ointment is prescribed. It has the following effect:

• heals wounds;
• improves tissue trophism;
• improves recovery processes;
• increases the flow of oxygen to tissues;
• stops bleeding;
• relieves inflammation;
• enhances the body's potential;
• improves the sensitivity of nerve endings.

Thanks to these features, the drug can be used to treat hypoxia or ischemia, when there is a lack of glucose or oxygen in the body’s tissues.

Indications for use

Often consumers do not know exactly what the drug helps with. The instructions for using the ointment state that it is used when and to eliminate:

• ulcers and wounds;
• bedsores;
• burns;
• skin grafting;
• eye damage;
• disruption of metabolic processes;
• insufficient blood circulation;
• venous insufficiency;
• hemorrhoids.

Based on these features, we can say that it is used in many medical profiles, and not just for eye treatment. It could be:

• ophthalmology;
• dentistry;
• phlebology;
• proctology;
• dermatology.

Instructions

The instructions for use for the ointment say that it should be used as follows:

1. The course of treatment is at least 12 days.
2. You need to apply the ointment at least 2 times a day.

• For ulcers and wounds of the skin and mucous membranes: use Actovegin 5%, apply in a thin layer.
• Bedsores and their prevention: rub into the right places.
• To prevent the appearance of radiation injuries: apply a thin layer of 5% ointment immediately after radiation therapy; this should be done in between procedures.

If desired effect does not occur after using the ointment, you should consult a specialist.

Contraindications

The medicine is used to treat many diseases.

Children are also allowed to use it, but only a doctor can prescribe it after a full examination and taking into account all the risks. Application is carried out only locally. In some cases, children this remedy poorly tolerated, just like during pregnancy.

Side effects

Typically, patients who have used the substance note its effectiveness. In some cases, the product may have a negative effect on the body. The whole point is that the substance contains elements of animal origin, which can cause allergies.

Most common negative impacts are as follows:

• rash;
• Redout;
• temperature increase;
• increased sweat production.

If such symptoms appear, then the use of the medicine should be discontinued. You must also remember that during initial use of the product it may cause minor painful sensations, but this should not be a reason to cancel the use of the substance. This pain is usually caused by regeneration processes. These sensations go away on their own.

Contraindications

The description of the ointment says that it cannot be used for:

• pulmonary edema;
• diabetes;
• sensitivity to components;
• oliguria;
• disorders in the respiratory system.

The ointment is prescribed with caution during pregnancy and children.

Currently, scientists have not yet figured out how the substance interacts with other drugs. There were no cases of overdose either. After using the product, you can drive a car, as it does not reduce reaction or impair the clarity of vision.

Analogs

The ointment also has cheaper analogues that are similar in action. You cannot prescribe one of these remedies yourself; only a doctor can do this:

• Solcoseryl - makes the skin healing process faster.
• Algofin - prescribed for skin lesions caused by radiation, abscesses and fistulas.

Which analogues are best to choose, including during pregnancy, is determined only by a doctor. Experts often prefer Solcoseryl.

Price

One of the most frequently asked questions for patients - how much the medicine costs. This ointment is quite cheap, the cost does not exceed 150 rubles. Prices in pharmacies may vary, but most often do not exceed 200 rubles.

The price of substitutes is also quite reasonable. So, Solcoseryl costs about 250 rubles per package.

Reviews

Judging by the reviews of patients, we can conclude about the popularity of the drug and its effectiveness, since most of the comments are positive. Also among the advantages are the availability and composition of the ointment. IN in rare cases the product may have a negative effect.

There are also negative reviews, but in most cases they are from those whose body does not tolerate the components of the drug, and therefore it causes side effects.

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Actovegin instructions for use in ophthalmology

"Actovegin" is a drug that activates tissue metabolism, stimulates regeneration processes and improves trophism. Available in the form of a solution for injection, solution for infusion, film-coated tablets, as well as in the form of ointment and gel.

In ophthalmology, eye gel is used. It is used for burns, corneal ulcers, keratitis of various origins and for the treatment and prevention of radiation damage to the cornea.

Release form and composition

The drug is available in five gram tubes, packaged in cardboard boxes, instructions are included. Actovegin eye gel is a homogeneous, transparent mass, colorless or slightly yellowish.

His active substance is a hemoderivative from calf blood (dry mass) deproteinized (eight milligrams). Auxiliary components include carboxymethylcellulose, sorbitol, lactic acid, thiomersal.

pharmachologic effect

This drug helps to activate metabolism in tissues, improves trophism and stimulates regeneration processes. In ophthalmology it is used topically.

"Actovegin" activates cell metabolism by increasing the transport rate and further accumulation of oxygen and glucose, enhancing intracellular utilization.

As a result, there is an increase in the energy resources of the cell, especially under conditions of ischemia and hypoxia.

Pharmacokinetics

It is impossible to study the pharmacokinetic characteristics (absorption, distribution, excretion) of a drug, since it consists of physiological components that are usually present in the human body.

Yes, today no decrease in pharmacological activity has been detected active substance in patients with altered pharmacokinetics (including renal and liver failure, age-related metabolic changes).

Indications for use

Actovegin eye gel is used:

• to eliminate corneal ulcers of various origins;
• for the treatment of corneal burns (lime, alkali, acid);
• for the purpose of prevention and treatment of radiation injuries of the cornea;
• for defects of the corneal epithelium in patients using contact lenses;
• for the prevention of lesions during the selection of contact lenses in patients with atrophic and dystrophic processes in the cornea (including age-related atrophic keratitis).

Dosage and method of administration

The drug is intended exclusively for local application. One or two drops of gel are squeezed directly from the tube into the affected eye.

The frequency of application is from one to three times per day. The duration of treatment is determined by the indications.

Side effects

Side effects of the eye gel include the development of reactions allergic type, which are observed quite rarely.

Contraindications

Contraindications to the use of this drug include: increased sensitivity to one or more of its components.

Use during pregnancy and lactation

The use of the drug "Actovegin" during lactation and pregnancy is allowed only if indicated.

Read the instructions for use of erythromycin ophthalmic ointment and find out for what diseases it is used.

You can learn more about the Vitalux Plus vitamin complex here.

Overdose

There are no reports of cases of overdose with eye ointment.

Interaction with drugs of other pharmacological groups

To date, no significant interactions of the drug with drugs of other pharmacological groups have been established.

special instructions

The use of the drug can be combined with the use of other forms of Actovegin.

Terms and conditions of storage

The drug must be stored at a temperature of eighteen to twenty-five degrees Celsius. Its shelf life is three years. After the package is opened, the eye gel can be used for no more than four weeks.

Pain in the eyes: causes and treatment

Pain in the eyes is not an independent pathology. A feeling of discomfort indicates the presence of a disease or injury to the organ of vision. It is often accompanied by other unpleasant symptoms.

This article is for informational purposes only. For detailed advice, you should contact an ophthalmologist.

Causes

Pain in the eyes usually appears in combination with the following sensations:

• lacrimation;
• dryness;
• pain;
• burning;
• redness of the sclera;
• photophobia;
• discomfort;
• formation of purulent discharge;
• swelling of the eyelids

If you experience watery eyes, pain or burning in your eyes, you should immediately contact a specialist. You cannot independently replace full-fledged treatment with the use of eye drops(Leksin, Slezin, etc.). It will only drown out pathological condition, but will not get rid of the source of the problem.

Antibiotic wide range actions for topical use in ophthalmology - instructions for use of Tobrex eye drops.

Often, when you are overworked, you may experience a burning sensation and increased lacrimation.

Symptoms can appear both together and separately. It depends on the cause of pain in the eyes:

• conjunctivitis (the most pronounced feeling of “sand in the eyes”, redness, lacrimation and the formation of purulent discharge);
• keratoconjunctivitis;
• blepharitis;
• application of some medicines(for example, to reduce blood pressure or stabilize the psychological state);
• general diseases of the body ( rheumatoid arthritis, lupus);
• production disruption natural tears;
• viruses (herpes, measles, etc.);
• demodicosis (appearance of mites in the interciliary space);
• overvoltage;
• incorrectly selected contact lenses;
• violations visual function(for example, astigmatism);
• allergic reactions;
• glaucoma;
• cyclite;
• eye injury or burn;
• factors environment;
• increased eye pressure;
• presence of a foreign body.

Adverse environmental factors affect the health of all body systems

When delay is like death! - The first symptoms of eye cancer are described in the article.

Environmental factors include:

• indoor humidity level;
• tobacco smoke;
• presence of dust or mist in the room;
• artificially created air flows (air conditioning or fan);
• direct sunlight.

Working at a computer and watching TV increases the risk of pain in the eyes due to:

• overload of the muscles of the organs of vision;
• infrequent blinking and slower production of natural tears;
• lack of movement of the eyeball;
• increased concentration.

Pain in the eyes often appears only in the morning. In this case, we can talk about the presence of problems with the tear membrane, fatigue, lack of sleep and overexertion.

Find out how to choose tint lenses with diopters here.

Long-term overvoltage eye muscles contributes to the appearance of unpleasant symptoms

Consequence of circulatory disorders eyeball - peripheral dystrophy retina.

Diagnostics

To identify the cause of discomfort, you need to undergo comprehensive examination at the ophthalmologist. It includes:

• eye swab;
• scraping from the interciliary space;
• examination of the lacrimal membrane;
• examination using a slit lamp;
• eye pressure measurement;
• examination using an ophthalmoscope.

To clarify general data, a patient survey is also conducted (use of contact lenses, adequate rest, work at the computer, etc.).

If necessary, a specialist can prescribe additional research and samples. Sometimes you need to see a doctor general practice for delivery general analyzes and identification systemic violations body work.

A modern method of vision correction and restoration is perifocal spectacle lenses.

The mandatory set of diagnostic measures includes measuring intraocular pressure

Acute therapy allergic conjunctivitis- instructions for use of Polinadim eye drops.

Treatment

Treatment for pain in the eyes is determined by the cause of its manifestation. On initial stage examination, the patient is prescribed moisturizers eye drops to alleviate the condition. With pronounced inflammatory process – antibacterial drugs. After diagnosis with:

• dysfunction of natural tear production - moisturizing drops and ointments (Korneregel, Actovegin);
• allergic reactions - antihistamines(Suprastin, Zodek) and local drugs(Okumethyl, Cromohexal, Allergodil);
• improper wearing or selection of contact lenses - their replacement and recommendations for use;
• In inflammatory diseases, treatment is selected depending on the pathology;
• burns and injuries - antimicrobial and healing drugs;
• demodicosis - treatment of eyelids with calendula tincture and by specialized means(Blefarogel, Demazol);
• General disorders of the body are treated by specialists.

Often patients with pain in the eyes are prescribed tetracycline ointment. It has the following effect:

• healing after burns and eye injuries;
• treatment of bacterial infections.

Levomiticin is the most common antibiotic used.

The duration of treatment is determined by the ophthalmologist. After completing the full course of restorative procedures, the patient must undergo a re-examination.

Antiviral and immunomodulatory drug! - Study the instructions for Poludan eye drops using the link.

The drug is indicated for disorders of natural tear production

Evidence of progression dangerous disease- clouding of the cornea of ​​the eye.

Demazol will help with demodicosis

This article will help you find out the causes of clouding of the lens of the eye.

Prevention

To the main preventive measures include:

• implementation proper care behind the eyes;
• correct selection of contact lenses and adherence to wearing regimen;
• regular visits to the ophthalmologist;
• use of sunglasses;
• compliance with safety regulations to avoid injury and burns;
• use of high-quality cosmetics;
• implementation gymnastic exercises for eyes;
• adherence to sleep and rest patterns;
• use of moisturizing eye drops for long work at computer;
• complete cure of infectious and viral diseases;
• strict adherence to all procedures prescribed by the ophthalmologist;
• use of glasses and contact lenses for visual impairment.

Important to use Sunglasses to protect the sclera of the eye from ultraviolet radiation