home Adviсe "Dufaston": side effects. "Dufaston": description, instructions, use, contraindications, composition, storage. Temporary gland of the endocrine system. The effect of dufaston on the body and ovulation

"Dufaston": side effects. "Dufaston": description, instructions, use, contraindications, composition, storage. Temporary gland of the endocrine system. The effect of dufaston on the body and ovulation

Many pathologies of the female reproductive system are directly related to the imbalance of hormones in the body. For normal health and a woman's ability to conceive and bear a child, it is necessary to maintain the main sex hormones at a certain level. The most important biologically active substances for the female reproductive system are estrogen and progesterone.

Gynecologists often prescribe hormonal drug Duphaston (Duphaston) for the correction of progesterone levels. When prescribing the drug as one of the most FAQ It is considered whether Duphaston affects weight. It is important for every woman to remain attractive even in the process of hormonal treatment.
To understand if there is a connection between taking Duphaston and the appearance extra pounds, you need to learn about the mechanism of action of the drug and indications for its use.

The effect of the drug on the body

Main active substance in Duphaston is a synthetic substitute for natural progesterone - dydrogesterone. This substance has the same effect on the body as the hormone progesterone, which is one of the main regulators menstrual cycle and pregnancy.

The menstrual cycle in a woman consists of two phases, the second phase begins after ovulation and it is during this period that progesterone is actively produced. This hormone also prepares the female reproductive system to pregnancy and childbearing. Influencing the receptors of the endometrium of the uterus, it contributes to its loosening and active vascularization. These processes are necessary for the successful attachment of the embryo to the uterine wall.

An insufficient amount of progesterone in the body can lead to pathologies such as spontaneous abortions, infertility and menstrual irregularities. Dydrogesterone compensates for the lack of progesterone in a woman and has a number of advantages compared to treatment with drugs based on natural progesterone:

well absorbed in the gastrointestinal tract, therefore, it has a convenient form of release in the form of tablets;
does not affect the metabolism of fats and carbohydrates in the body (so excess weight from Duphaston does not appear);
has no masculinizing effect(when taking the drug, there is no coarsening of the voice, the appearance unwanted hair on the body);
does not affect basal body temperature body(convenient for women who calculate the time of ovulation and practice calendar method contraception).

Since dydrogesterone does not violate metabolic processes in the body, then a woman cannot gain weight from Duphaston.

If you started to get better after taking this drug, then you may have previously had problems with the metabolism of fats and carbohydrates. Also, Duphaston does not cause such side effects as weakness, sleep disturbance, headaches and sharp drops moods.

If you feel a deterioration in general well-being during treatment, then you may have an individual intolerance to one of the components of the drug. Also drink these hormonal pills contraindicated in women with rare hereditary pathologies liver (Rotor syndrome, Dubin-Johnson syndrome). According to reviews from taking Duphaston, there is no weight gain, however, some patients may be dissatisfied with the treatment due to the fact that they have gained a few extra pounds. To find out about all possible consequences reception medicinal product, consult with your physician.

Why is the drug prescribed

Duphaston is used for many diseases of the female reproductive system. In modern gynecological practice doctors often prescribe hormonal agents and many of them have side effects of one kind or another. When taking Duphaston, most women do not experience an increase in body weight, and Negative influence drug on weight has not been proven in the course of scientific and clinical trials. If during the treatment you notice the appearance of extra pounds, then this may be due to your individual reaction to the drug or other diseases. endocrine system.

Indications for the use of this drug are:

menstrual irregularities;
infertility;
threatened miscarriage;
pregnancy planning, provided that the woman has had miscarriages in the past;
pronounced premenstrual syndrome;

If, in the presence of the above diseases, treatment with Duphaston is effective, then, despite weight gain, you need to continue taking the pills. It is also desirable to look for the cause of changes in body weight. Very often women get better on the background of inaccuracies in the diet, sedentary image life. Stress also often causes obesity in the beautiful half of humanity. Since in most cases it is impossible to gain weight from Duphaston, the state of the pancreas should be examined, and the levels of insulin and glucagon in the blood should be checked.

Reading time: 7 minutes

With progressive problems with ovulation on early term pregnancy on Duphaston proceeds successfully, and the gynecologist prescribes this medication for individual correction of the hormonal background. The medication should not be the result of superficial self-treatment, the correction of hormones is purely individual. Difficulties caused successful conception insufficiency of progesterone, therefore, in order to safely become pregnant, it is required to correct the disturbed hormonal background by medication.

What is Duphaston

This combined hormonal drug stimulates the production of progesterone in the concentration necessary for successful conception, while not having a detrimental effect on the liver. The medicine can be bought at a pharmacy, a doctor's prescription is not required. Among the hormonal drugs in the composition replacement therapy it is a reliable remedy that can be used until the third trimester in the fight against progesterone deficiency. Duphaston is recommended for pregnancy, but it is also used to safely carry the baby.

Therapeutic action Synthetic hormone systemic, according to the instructions for use, has the following pharmacological features:

prevents relaxation of the muscles of the uterus;
increases the susceptibility of the endometrium;
normalizes the immune response female body;
protects and seals the thinned endometrium;
saves a long-awaited pregnancy;
guarantees complete implantation gestational sac.

Why are they prescribed

To stabilize ovulation and, thereby, increase the chances of successful fertilization, doctors recommend taking a full course of Duphaston. This real help the natural hormone progesterone, which is produced by the female body in insufficient quantities and prevents a woman from becoming pregnant. The main indications for use are presented below:

How to get pregnant on Duphaston

If there have been abortions or missed abortions in a woman's life, successful conception is possible after the course of Duphaston. With such safe methods at home, you can soon wait for the desired delay and the cherished two strips on the test. So, in case of malfunction of the ovaries (anemorrhoea), doctors recommend Duphaston tablets, while hormone therapy must necessarily be combined with physical activity And therapeutic diet. To compensate for the deficiency of progesterone, the drug is supposed to be taken in the second phase of the cycle. The therapeutic effect is:

prevents bleeding in the middle of the cycle;
reduces pain during unstable menstruation;
reduces the symptoms of premenstrual syndrome.

Does Duphaston affect the pregnancy test

A characteristic medication is hormonal in nature, but it does not affect the veracity of the pregnancy test response. The fact is that hCG, which determines successful conception, is produced only after the attachment of the fetal egg to the wall of the uterus. Then the pregnancy test will be positive. A false answer is also possible, but in this case it is more associated not with taking Duphaston, but with the purchase of low-quality pharmacological products from the manufacturer. So the drug itself does not affect the response of the test strip.

Is it possible to drink Duphaston during pregnancy

A characteristic medication is allowed to be taken not only in the first and second trimester, but also before the onset of the harbingers of childbirth. Harmful effect on intrauterine development is completely absent, but such in a conservative way you can avoid miscarriage in the first trimester, uterine bleeding and hypertonicity. If the lack of ovulation is due to a malfunction of the synthetic hormone in the blood, doctors prescribe Duphaston. Ideally, it is appropriate to take the medication until the 16th obstetric week. However, longer courses of treatment are also possible.

Signs of pregnancy while taking Duphaston

If you drink Duphaston during pregnancy planning, the chances of successful conception increase significantly. With successful fertilization of the egg, the reaction of the body future mother more intense, the following changes occur in general well-being and behavior of a pregnant woman:

constant feeling of hunger, increased appetite;
a feeling of fullness in the abdomen, a feeling of heaviness;
delayed scheduled menstruation;
noticeable breast growth hypersensitivity;
frequent urination, especially at night;
habitual signs of toxicosis;
increase in basal temperature;
soreness and increased sensitivity of the mammary glands.

Indications for use during pregnancy

With previous abortions, the doctor after the next onset of conception recommends taking a course of Duphaston. Tablets help to get pregnant, contribute to the thickening of the endometrium, the timely formation of the placenta. Main medical indications for the use of this hormonal preparation are presented below:

early uterine hypertonicity;
impending threat of miscarriage;
previous abortions at an early stage;
early abortions, mechanical curettage of the uterus;
genetic predisposition to diagnosed infertility;
hormonal imbalance.

Instructions for use in the early stages

The first step is to determine the prevailing in a particular clinical picture causes of infertility and prolonged absence pregnancy, and then eliminate the main pathogenic factor. Duphaston in early pregnancy is recommended to be taken orally until 20 obstetric weeks or up to 4 months, until the placenta is finally formed. Diagnosis of the hormonal background can be determined by a blood test, a comprehensive examination.

To keep the pregnancy

Duphaston during pregnancy is prescribed in the first trimester to prevent miscarriage. The recommended dosage in the early stages is up to 40 mg per day. These are 4 tablets, which are required to be divided into 4 daily oral doses. An overdose is excluded, otherwise you can harm the female body with existing hormonal disorders.

Dosage

Daily dosage medicinal product Duphaston during pregnancy in the early stages is determined purely in individually, adjusted by the attending physician. In addition, regular blood tests are required to monitor hormonal levels and its changes. According to the specified laboratory study, one can judge the positive dynamics, if any, is observed after the course hormone therapy. For treatment, Duphaston is intended to be taken orally at 20 mg per day for 7-10 days. In the future - 10 mg of the hormone per day until the 14th obstetric week of pregnancy.

How long to take Duphaston during pregnancy

Duphaston and pregnancy are quite compatible concepts, if you are not guided by superficial self-medication, but strictly follow medical recommendations. It is recommended to take a characteristic medication up to a maximum of 16 obstetric weeks, after which it is advisable to adhere to the synthetic hormone withdrawal scheme. The recommended dose should be reduced gradually, since the so-called “addictive effect” prevails in the pregnant body, a hormonal surge is not excluded.

Side effects

A characteristic medication is not suitable for all women who have problems with successful conception. It's important to be wary side effects that progress at the very beginning of the treatment course. The doctor rarely introduces a correction of the daily dosage, more often resorts to the help of an analogue of this pharmacological group- Morning. Pregnancy against the background of Duphaston may be at risk. Potential side effects are as follows, disappear only after the withdrawal of the indicated medication:

from the side of the central nervous system: systematic attacks of migraine, dizziness, dull headache, general weakness, poor sleep;
from the gastrointestinal tract: paroxysmal abdominal pain, severe liver dysfunction, physiological jaundice, signs of dyspepsia;
on the part of the reproductive system: hypersensitivity of the mammary glands, breast enlargement, uterine bleeding, imbalance of estrogen and testosterone;
from the side skin: local reactions on the mucous membranes, peripheral edema, allergic reactions (skin rash, itch, anaphylactic shock, angioedema);
on the part of the hematopoietic organs: progressive hemolytic anemia.

The synthetic hormonal drug Duphaston is not recommended for women with chronic pathologies heart, liver, kidneys, pancreas. Such a pharmacological prescription is dangerous for recurrent diseases of the endocrine system, lesions thyroid gland. Before the beginning hormonal course recommended to pass full examination the female body for hidden diseases.

Can duphaston terminate a pregnancy

At systemic use pregnancy on Duphaston proceeds without pathologies. Many future mothers are sure of the opposite, therefore they are afraid to be treated with hormones when carrying a fetus in the early stages. According to medical beliefs, a characteristic medication of a hormonal nature is considered absolutely harmless and safe method infertility treatment, provides reliable protection fetus from a highly undesirable death. According to statistics, real cases threats of progressing pregnancy were not recorded.

How to painlessly stop taking the drug

The abolition of the characteristic medication must be introduced gradually, not forgetting that the tablets for oral intake Duphaston is, first of all, synthetic hormones. For example, shorten daily dosage you can take half a pill a week to eliminate hormonal breakdown and extremely unwanted interrupt early pregnancy. It is desirable to coordinate the most suitable schemes for the withdrawal of a medicinal product individually with the local gynecologist.

Video

We all know that the presence or is almost the main indicator women's health and ability to conceive and have a child. that is why, if at the doctor's appointment, you were prescribed medications, which affect hormonal background, you are probably wondering what effect they will have on ovulation. In today's publication, we will talk about such a hormonal drug as Duphaston and its effect on a woman's ovulation.

So what is ovulation?

Ovulation is the release of an egg from the ovary, which is the most. At the same time, in the first half of the woman's menstrual cycle, the egg matures, and in the second - its release, which is the process of ovulation. However, in some cases, it happens that the egg is not able to fully mature, which means that ovulation does not occur and it becomes impossible to get pregnant. It also happens that the egg matures, but due to a lack of luteinizing hormone from the pituitary gland, which promotes the release of the egg from the ovary, ovulation does not occur. In addition, if a woman's body does not have enough female hormone progesterone, then pregnancy, if it occurs, ends in spontaneous miscarriage.

To solve all of the above problems, as well as for hormonal deficiency in the second half of the menstrual cycle, as a rule, women are prescribed a synthetic analogue of progesterone, such as Duphaston. The drug has proven to be very effective remedy, which almost does not cause side effects and does not affect ovulation.

I prescribe Duphaston to women who have been diagnosed with infertility caused by a lack of progesterone. In this case, the drug is taken from the second half of the menstrual cycle from the 14th to the 25th day of the menstrual cycle, because it in no way affects the release of the egg from the ovary and provides an excellent opportunity for its fertilization. Besides. even after the onset of pregnancy, it is recommended to continue treatment with progesterone in the first trimester to prevent miscarriage and other intrauterine development of the unborn child. For women diagnosed with uterine hypertonicity, duphaston is prescribed until the end of the second trimester of pregnancy.

It is important to note that with insufficient hormonal supply in the second half of the menstrual cycle, the uterine mucosa sometimes cannot secrete enough secretion, which in turn prevents the fertilized egg from attaching to the uterine cavity, which leads to. In addition, changes in the uterus against the background of chronic inflammatory processes can also cause this anomaly. That is why taking Duphaston is the most humane and reasonable solution for maintaining pregnancy.

This hormonal drug is prescribed during pregnancy planning, for successful conception and the onset of a long-awaited pregnancy. The doctor selects an individual treatment regimen, taking into account the days of ovulation, which after 3-6 months of treatment leads to the successful conception of a baby. Some women manage to get pregnant earlier - it all depends on the degree of the disease.

Answering the question of many women about whether taking Duphaston affects ovulation, it is important to note that representatives of the drug manufacturing company claim that, according to clinical research, with normal therapeutic doses Dufaston does not suppress ovulation and is not an obstacle to conceiving a child. However, we do not undertake to confirm the information for 100%, since it is impossible to predict in advance the individual reaction of the body to the drug. Yes, and this should be dealt with by a specialist.

Especially for Ira Romaniy

Dufaston is an artificial analogue of the female sex hormone progesterone. It is prescribed to women who have reduced production of natural progesterone, which leads to such phenomena as or their complete absence, habitual miscarriage, severe premenstrual pain and others.

Duphaston brings with it few side effects and, since it does not affect ovulation, pregnancy can occur while taking this drug. However, it cannot be said that Duphaston is completely safe and does not threaten with any side effects.

Among the most common side effects from taking Duphaston are bloating, headaches and dizziness, and nausea. The drug has hormonal effects- as a result hormonal changes disorders in the body, breast sensitivity may increase, acne may appear, change sex drive(both in the direction of increase and vice versa), minor bleeding appears between periods, weight increases.

In some, although rare cases, Duphaston leads to anemia and abnormal liver function. In addition, you need to be careful if you have a tendency to allergies. Some women are allergic to didrogestron, one of the components of the drug. It appears as a rash.

A contraindication to taking duphaston is the presence in the patient's history of cardiovascular disease, diseases of the liver and gallbladder, ovarian and breast cancer.

Among the side effects of taking Duphaston:

genitals - breakthrough uterine bleeding, increased sensitivity of the mammary glands;
central nervous system- migraine;
gastrointestinal tract- general weakness and malaise, impaired liver function, jaundice, abdominal pain;
skin - rash and itching;
hematopoietic system - homolytic anemia (rare);
allergic reactions such as hives and angioedema;
extremely rare, but still occurs - peripheral edema.

Contraindications to the appointment of Duphaston

First, it is an individual intolerance constituent components drug, rash and skin itching during a previous pregnancy, breastfeeding period. Secondly, Duphaston is not prescribed for certain types of enzymatic deficiency, as well as for malabsorption syndrome.

Before the appointment of Duphaston, it is necessary to undergo an examination. According to its results, the doctor must determine the dosage and duration of the course of taking the drug.

Reviews about the drug

If we talk about the opinions of women who took this drug for one reason or another, then they differ somewhat. Some patients speak of Dufaston only positively, saying that it was thanks to him that they managed to get rid of, save the pregnancy and bear the baby.

Others complain of multiple side effects, constant dizziness and nausea, unexplained discharge between periods, and changes in the menstrual cycle.

Of course, it is impossible to predict who will be affected. side effects the drug, and whom they will bypass, but it is extremely important to take it strictly according to the scheme drawn up by the doctor and not deviate from it. Also, you can’t act for your own purpose - at the same time with a girlfriend.

Despite the recognition of the safety of the drug, if taken incorrectly, Duphaston threatens with serious consequences in the form of a menstrual cycle failure, which is very difficult and long to restore. And it is especially dangerous to experiment with taking Duphaston during pregnancy - this can lead not only to the manifestation of side effects, but also to irreversible consequences.

Planning for a future child is carried out taking into account many different factors. The question of what is the influence is quite relevant today. This hormonal type drug is widely used in modern gynecology. Its main purpose is considered to be used for malfunctions in the menstrual cycle and if the patient has endometriosis.

Given medication actively used during pregnancy planning. Most experts consider this drug very effective. Before taking this medication, you should understand the question of how the effect of Duphaston on the fetus can be reflected in health future mother. The sanitation process through this medication must be accompanied by mandatory supervision by a specialist.

Characteristics of the drug

Today, many gynecologists practice the appointment of such a drug as Duphaston. Its basis is substance active action called dydrogesterone. This element belongs to the group synthetic hormones and is considered an analogue of natural progesterone. Practice shows that this natural substance is intended primarily to prepare the endometrium of the uterus for full pregnancy. After conception, progesterone plays a key role in the preservation of the ovum. The above substance is produced by the ovaries, namely their corpus luteum. As a rule, this occurs at the end of the menstrual cycle.

In the case of successful conception, the concentration of this hormone in the body of a woman increases significantly. If pregnancy does not occur, then the level of progesterone decreases. This hormonal substance plays important role in the process of fat accumulation, development of the mammary glands, relaxation of the uterus and intestines in the body of the expectant mother. With a significant woman, she may experience great difficulties during the planning of pregnancy or immediately upon its occurrence. The above problem negatively affects the ability to become pregnant. In many cases, a lack of progesterone leads to the problem of persistent miscarriages. Also a large number of women have serious difficulties in conceiving a child.

Due to the occurrence of the above negative factors due to the lack of progesterone, most doctors prescribe Duphaston. A specialist can advise the use this tool during pregnancy planning or after its onset. Thus natural hormone is replaced by a synthetic one and all the above problems are eliminated. Most experts say that Duphaston has a very positive effect on pregnancy. The drug in many cases eliminates real reasons infertility. Strongly not recommended self-treatment this medicinal product. Before taking it, a woman should consult a doctor.

The essence of the problem

In the process of carrying a baby, doctors prescribe Duphaston to a woman only if she has already had abortions or the fetus has died. A one-time abortion does not apply to the above cases, with this option, experts do not always recommend taking this medication. It is strongly not recommended to use this drug in order to prevent miscarriages. It is not given to every patient. The gynecologist recommends it strictly on an individual basis only to those women who have shown the above problems.

Often this medicine used at the stage of planning the conception of a child. Before this, a woman should be checked for the amount of progesterone in the body. If the test results show that the level of this hormonal substance is lowered, the patient is recommended to take Duphaston. Such a check should be done in the second phase of the menstrual cycle. Practice shows that taking the drug may be accompanied by the following side effects:

dizziness;
nausea;
headache;
allergy;
vaginal bleeding.

Doctors recommend the use of Duphaston after a missed pregnancy only if the patient is carefully checked for a decrease in her progesterone. If this fact is not confirmed laboratory research, then the miscarriage could occur for a completely different reason. For example, constant stress, illness inflammatory nature, infections can also have a very negative effect on pregnancy and cause its termination. Reception of Duphaston should not be completed if conception occurred after the start of its use. Otherwise, a sharp decrease in progesterone in the blood can provoke a miscarriage. Doctors insist on the gradual abolition of this drug when used during pregnancy. It is important to remember that this medication should only be taken on the strict prescription of a specialist.