Is it possible to drink Proginova and Duphaston at the same time? Benefits and side effects of hormonal drugs. Features of joint use. Indications and contraindications. Planning pregnancy and prescribing medications
Today, quite often, women for treatment or prevention reproductive sphere discharged hormonal medications, however, few people know what side effects they can cause. In our article, we suggest that you familiarize yourself with the part of the instructions for use of the drug Duphaston, which concerns side effects, and will also tell you whether it is worth taking the medicine for.
Characteristics and description
"Duphaston" is a synthetic analogue of one of the most important female genitals. Its peculiarity is that it does not affect pregnancy in any way, so it is quite possible to become pregnant while taking it.
The medicine is produced in the form of tablets, around which there is a coating. It has a large number of indications, therefore it is used to combat many diseases.
Let's look at why Duphaston is prescribed:
- Luteal insufficiency, as a result -.
- Availability .
- The presence of a pronounced
- When threatened, after it.
- For dysfunctional uterine bleeding.
- If there is a secondary one.
- Recovery .
Side effects during use
Unfortunately, except positive result in treatment, Duphaston has side effects. Let's take a closer look at the effect it has on the body.
Headaches and migraines
Taking Duphaston leads to an increase in concentration. Hormonal surges affect the central nervous system and can cause headaches or migraine attacks.
If you notice similar symptoms while taking Duphaston, you should immediately report them to your doctor and stop taking the medicine.
Hemolytic anemia
One of the serious side effects when taking Duphaston is the development hemolytic anemia- deviation in work circulatory system. It causes destruction of red blood cells in the blood.
Depression
Unfortunately, long-term use The drug can also affect the woman’s psyche. An unpleasant side effect in this case is depression. In this case, there are symptoms such as fatigue, apathy, lethargy, lack of mood and desire to do anything.
Getting into the human blood, progesterone also affects the mucous membranes gastrointestinal tract. Therefore, women often complain of a feeling of nausea, but vomiting is observed in isolated cases. 
Liver dysfunction
When taking Duphaston, side effects may occur in the liver. At the same time, women note the appearance of weakness, abdominal pain, and jaundice may begin. If you have liver problems, taking the medicine is strictly prohibited.
Uterine bleeding
Unfortunately, if it turns out that the pills are not suitable for you or they were prescribed incorrectly, this can lead to breakthrough bleeding from the uterus, which can occur as a result of an insufficient dose being prescribed. In addition, women note increased sensitivity breasts
Itching and allergic reactions
Hormones can also affect the skin, subcutaneous tissue. An allergy to Duphaston is often noted, which is manifested by itching, raw materials, urticaria, and sometimes Quincke's edema.
One of the main purposes of Duphaston is normalization menstrual cycle, however, sometimes failures may occur in the first months of use. 
Some women note that their body weight increases while taking the drug. However, there are no clear reasons to connect this with Duphaston.
The only thing worth paying attention to is that the drug can promote fluid retention in the body, which in turn can affect weight. However, if you stick proper nutrition, engage in moderate physical activity, taking the drug will not affect your body weight.
Special instructions and contraindications
If taking the pills is part of HRT, you should detailed analysis anamnesis. In addition, the attending physician should warn the patient about what changes in the breast require increased attention.
If breakthrough bleeding from the uterus continues after completion of the therapeutic course, it is worth sending part of the endometrium for a biopsy in order to exclude the presence of malignant changes.The main contraindications to taking Duphaston include:
There are many analogues of the drug, but you should not decide on your own which medicine to take. Only experienced specialist will be able to choose a drug based on your situation.
After reading our article, you learned how Duphaston can be dangerous and in what cases it is prescribed. Any treatment should be carried out under the supervision of a doctor - only in this case can you achieve a positive result and not harm your health.
– a synthetic gestagenic drug that increases the content of native progesterone in the blood. – natural preparation progesterone, which can be taken during pregnancy, miscarriage, hormonal disorders associated with insufficiency corpus luteum. Often during pregnancy, utrozhestan and duphaston are prescribed simultaneously. Is it possible to take these two drugs together, will there be any consequences from such a prescription? negative consequences for the fetus? This question is of great concern to expectant mothers.
Are the drugs prescribed together?
It is indeed possible to take Utrozhestan and Duphaston, but such prescriptions are given only during pregnancy with a clear lack of progesterone in the body in the early stages, as well as with the threat of miscarriage and placental abruption. There are often cases where a woman took one duphaston, but it had no effect on increasing the reference values of the hormone progesterone. In this case, the additional use of utrozhestan is indicated, but in the form vaginal suppositories so that there is no risk of hormone overdose. The intravaginal method of using the medication is good because it promotes rapid penetration of the medicinal component to the uterus, so the effect appears almost immediately.
In what other cases are medications prescribed together?
If a woman becomes pregnant through in vitro fertilization, then to create suitable conditions For embryo development, both drugs are prescribed together. This prescription allows you to maintain optimal hormonal levels in the body and prevents spontaneous abortion in the early stages. Also, during the period of gestation, both of these medications can be prescribed in for preventive purposes, If:
- The pregnancy was difficult to achieve, and the woman was previously treated for infertility for a long period of time
- Previous pregnancies ended unsuccessfully - frozen pregnancy, miscarriages, abortions
- Last time a woman gave birth prematurely
- History of gynecological diseases
- Hormonal imbalance
- Uterine anomalies.
If a woman experiences uterine bleeding and direct signs of miscarriage, then it is necessary to go to the hospital, where the maximum possible dosages of progesterone will be prescribed in order to prevent spontaneous termination of pregnancy.
In the second trimester, especially after 20 weeks, duphaston is no longer prescribed orally, since the work digestive system pregnancy changes, due to which the oral form of synthetic gestagen becomes practically inactive. Intravaginal administration of utrozhestan improves the strength of the cervix and also prevents the onset of premature birth. In the third trimester after 34 weeks, the use of any gestagens is contraindicated.
It’s great when your menstrual cycle is stable and you don’t need to take anything to ovulate. But if you look around, you can see a lot of girls attending antenatal clinics, undergoing tests, and undergoing treatment courses. Problems with conception are often caused by hormonal disorders, and one of the drugs that solves these problems and is prescribed when planning pregnancy is Duphaston. Let's talk about him.
When tests show that there is little in the body, doctors recommend the drug Duphaston. This remedy helps restore normalcy and helps you get pregnant.
The medicine is prescribed when the body does not produce the required amount of progesterone. Sometimes it is not canceled until the third trimester - at this time it is already formed, producing progesterone. The drug is absolutely safe even for a pregnant woman and baby. It also does not affect blood clotting and does not negatively affect the liver.
Is it possible to get pregnant after taking Duphaston? Yes, many gynecologists recommend this remedy, as it has shown excellent results.
You can get pregnant on Duphaston - it compensates for the lack of progesterone and is its synthetic analogue.
Doctors prescribe the drug in cases where problems with conception are associated with a lack of the hormone:
- uterine bleeding;
- amenorrhea.
It is important for the patient to know exactly how to drink Duphaston in order to become pregnant. The drug must be taken on certain days of the menstrual cycle, otherwise it can act as a contraceptive.
Does Duphaston help you get pregnant? Yes, because it contains artificial progesterone, called the “pregnancy hormone”. IN natural conditions its production occurs on the postovular days of the cycle, preparing the uterus for possible conception. To determine whether the cause of problems with conception is really deviations in hormonal background, you need to go to the antenatal clinic and get tested.
How to take the drug Duphaston if you are planning a pregnancy in the near future? Usually they start taking it from the 16th to 25th day of the menstrual cycle. If pregnancy has occurred, then use continues until week 20, after which the dosage is gradually reduced.
Doctors prescribe the drug for at least three months. If conception has not occurred during this time, Duphaston can be taken for up to 6 months.
Effect of the drug on the cycle
U healthy woman Menstruation should be monthly. Occasional cycle failures may be acceptable as long as they are intermittent. Long delays can be caused by insufficient progesterone. The indication for taking Duphaston is amenorrhea, which is caused by a malfunction of the ovaries. When a diagnosis of “secondary amenorrhea” is made (no periods for more than 6 months), doctors prescribe hormonal treatment, which is combined with physical activity and diet.
They drink Duphaston in the second phase of the cycle, replenishing the progesterone deficiency. Menstruation should become regular while taking the drug.
Sometimes women themselves begin to take the drug to combat amenorrhea, without first consulting a doctor. This cannot be done, because even greater violations may appear in endocrine system, which will be very difficult to cope with.
The drug can help prevent bleeding that occurs in the middle of the cycle, and it also reduces pain during menstruation. But to be positive effect, you need to drink it regularly.
Contraindications for use
Will Duphaston help you get pregnant? Of course, yes, but doctors must take into account both indications and contraindications for its use. An incorrect attitude to this issue can negatively affect a woman’s health.
The main contraindications are as follows:
- chronic renal failure;
- hypersensitivity to the components of the drug;
- hereditary pathologies, for example, Dubin-Johnson and Rotor syndromes.
Before taking the drug Duphaston when planning long-awaited pregnancy, you need to pay attention to your health. For example, if a patient has problems with cardiovascular system or diabetes, she needs to be careful when taking this drug. The doctor must constantly monitor her health.
You can take Duphaston to get pregnant with peace of mind, as it is safe. The same applies to the period of pregnancy itself. But during lactation, it is advisable that the patient does not drink it. The main component of the drug, dydrogesterone, is excreted in mother's milk and makes it impossible breast-feeding baby.
Taking the drug correctly
Before taking the drug Duphaston when planning a pregnancy, you need to read the instructions and remember that only a doctor can prescribe it. He monitors the patient and is familiar with the peculiarities of the course of the disease.
Rules of admission for various pathologies:
- PMS and irregular critical days- from 11 to 25 days of the menstrual cycle. When planning pregnancy, Duphaston is taken in a dosage of 10 mg twice a day.
- Dysmenorrhea (mild critical days) - from 5 to 25 days. Dosage: 10 mg twice a day.
- How to take Duphaston to get pregnant with amenorrhea? From 11 to 25 days of the expected cycle. Dosage: 10 mg twice a day. Additionally, you need to take estrogen.
- Duphaston for endometriosis during pregnancy planning is taken from 5 to 25 days. Dosage - 3 times a day, 10 mg.
- In case of infertility due to a lack of progesterone, the drug is taken from the 14th to 25th day of the cycle. When planning pregnancy, the dosage of Duphaston in these circumstances is 10 mg once a day. The course lasts 6 cycles in a row. If Duphaston helped you get pregnant, then you should not stop taking it for another 3 months.
- The drug copes well with uterine bleeding. In this case, you need to take it for 7 days, 10 mg twice a day.
Use during pregnancy
So, you can get pregnant while taking Duphaston, but is it allowed to take it after conception? Pregnancy sometimes occurs with complications, so it is necessary to take this remedy in order to safely carry the baby. If uterine bleeding is observed, the doctor may extend the course of therapy.
Discontinuation of the drug is developed by a doctor, since abrupt withdrawal often provokes a negative reaction. If the pregnancy is progressing normally, the dosage of the medication is reduced by half, and the woman’s well-being is monitored by the attending physician. If there are fluctuations in the level of the hormone progesterone due to a decrease in dosage, the process of stopping the medication will continue for another 2-3 weeks.
Those who have been helped by Duphaston to become pregnant should remember that they should not drink it after childbirth, because it has a negative effect on the baby’s body, getting there along with mother’s milk.
Duphaston or Utrozhestan - which is better?
The role of the first drug in planning conception and a successful pregnancy is well known. However, there are also effective analogues.
The main competitor of this drug is also very effective when planning conception. The drug contains progesterone, made from plant materials. For this reason, it is used in exactly the same way as its counterpart described above. There is no big difference in what to use when planning pregnancy - Duphaston or Utrozhestan. The doctor decides which specific drug to give preference to.
The difference between these medicines is that Duphaston - synthetic drug, and Utrozhestan is natural. But the first one has much fewer side effects.
The significant difference between these drugs is that Utrozhestan can not only be drunk, but also injected directly into the vagina, which prevents the development of allergic reactions. The doctor will decide which drug to prescribe for therapy.
Side effects from taking Duphaston
Duphaston can be used when planning pregnancy because it has few side effects. It does not affect ovulation, and conception often occurs when taking it. But it is not 100% safe. There are such side effects like nausea, dizziness, bloating.
Taking Duphaston when planning pregnancy in in rare cases may cause liver dysfunction and anemia. It is not recommended for women with pathologies of the heart, liver, kidneys, or pancreas.
To prevent side effects, you need to know how to take synthetic Duphaston correctly when planning a pregnancy. First, an examination is carried out, based on which the gynecologist determines the duration of treatment and the required dosage.
When a doctor recommends taking Duphaston when planning a pregnancy, there is no need to refuse - the drug is safe if you follow the instructions for its use. The medicine has proven itself well. If a woman is wondering whether it is possible to get pregnant on Duphaston, then she needs to know that only correct application This drug, under the supervision of a specialist, will help solve the problem.
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Problems with conceiving often occur because the body does not have enough of a hormone called progesterone, which prepares the endometrium to receiving the egg. The pregnancy hormone also ensures its normal course. Its synthetic analogue, the drug Duphaston, helps replenish progesterone reserves.
How to take medicine correctly
In any case, it can only be taken in consultation with the attending physician. It is necessary to drink the drug in accordance with the diagram or instructions - when the second half of the cycle begins its countdown.
The active components of the tablets do not affect ovulation itself and do not cause its inhibition. Their task is to prepare the inner layer reproductive organ to acceptance and subsequent implantation fertilized cell.
Take the drug 1 capsule twice a day, starting from the 11th or 14th day of the cycle. More exact date determined through testing.
You need to stop taking the medication on the 25th day of the cycle.
When the course of taking Duphaston is completely completed, but there is still no pregnancy, the drug is no longer used. Hormonal imbalances it does not give, so the body calmly tolerates its presence or absence.
Features of treatment for irregular cycles
When clear frequency the menstrual cycle is not observed, then the use of the drug is permissible only after ovulation has passed. If you take the pills until the egg has left the ovaries, you can get the exact opposite effect.
The active components of the drug in this case will have a suppressive effect. If the cycle is irregular, then you need to consult a doctor, get tested to determine the day of ovulation, or measure it yourself basal temperature body and calculate it.
You can also track the moment the egg is released using ultrasound, but it is better not to use this method often, so as not to do not exert mechanical influence on a sensitive organism.
Reception scheme
It is necessary to drink Duphaston in order to get pregnant in accordance with a certain scheme:
- When tests reveal a lack of the necessary hormone, 1 capsule is prescribed in the morning and evening, starting from the 14th to the 25th day of the cycle.
- In the absence of pregnancy, after using synthetic progesterone, normal menstruation will begin.
- If it is not possible to become pregnant after three months, a additional examination, and then the dose of the medicine is doubled - up to 2 tablets per day from 14 to 25 days menstrual cycle.
- When diagnosing a recurrent miscarriage, the drug should be taken 2 capsules per day - in the morning and evening time. In this case, taking Duphaston does not stop even after the implantation of the fertilized egg into the endometrium. You will need to drink it until the fifth month. Then the dosage is gradually reduced.
Before and after meals
It is advisable to take the drug half an hour before meals for its effective absorption by the body, but every woman's reaction the medicine is individual. Some people experience nausea if taken on an empty stomach. This may be caused by damage to the gastric mucosa as a result of ulcers or gastritis.
How to take the drug for endometriosis
When endometriosis bothers you, it can be treated with the drug Duphaston. It will help reduce pain, will not suppress ovulation and disrupt the menstrual cycle.
While taking the medicine, it becomes easier to get pregnant thanks to active work active components of the drug. For endometriosis, it is prescribed in an amount of 10 mg 2 to 3 times a day from 5 to 25 days of the menstrual cycle. Therapy lasts from six months to 9 months.
What dosage is needed
It is determined in agreement with the attending physician, but if necessary, take Urgent measures, but there is no opportunity to consult, the dose is determined by the instructions.
For infertility, Duphaston is taken 10 mg every day in order to get pregnant, from days 14 to 25 of the cycle for six months. If there is a threat of abortion, take 40 mg of the drug at one time, and then 1 tablet at intervals of 8 hours until the condition stabilizes.
If there is no period for a long time, but there is no pregnancy, then taking the drug is accompanied by taking estrogen once a day. At uterine bleeding 10 mg of medication is prescribed twice a day.
Features of admission if the cycle is 25 days
A normal time indicator of the menstrual cycle in women can be considered a periodicity from 24 days to 35, therefore, even in the same person the cycle may shift with a difference of 10 days, and this will not be considered a deviation. Therefore, on the 14th day of the cycle, if it is 25 days, it is too late to take the drug.
It is necessary to learn how to independently determine the days when a fertilized egg is released from the ovaries. To do this, you need to measure your basal body temperature every day - put a thermometer in your mouth, rectum or vagina in the morning. The procedure is done within a month.
On the day of ovulation, temperature will rise a little higher, than usual. After this or the next day, you can start taking the drug according to the instructions.
If the cycle is 30 days
When a woman’s menstrual cycle is exactly one month long, there is no point in taking Duphaston on the fourteenth day after it starts, as this can only cause harm. In this case, it is recommended, as with a 25-day cycle, to measure basal temperature throughout the month.
For convenience, you can use special electronic thermometers; they determine the temperature faster and provide more accurate information. When the day of ovulation is determined, you can start taking the drug - 1 capsule each twice a day for two weeks.
It is advisable to coordinate this period with the doctor.
Why is it important to take Duphaston after ovulation?
If you calculate the duration of the cycle and the approximate day of release of the fertilized egg incorrectly and start taking medication ahead of schedule, then the effect will be the opposite.
In this case, pregnancy will not take place. In order for cell implantation into the endometrium to occur successfully, it is important to correctly calculate the day of ovulation and only after it begin to take the drug in the prescribed doses. Then inner surface the uterus will be ready accept a fertilized egg, and pregnancy will proceed in a healthy direction.
At correct use"Duphaston" interesting situation won't keep you waiting long.
Carefully read the instructions before using the drug, consult your doctor in time and take into account the length of the menstrual cycle for optimal choice the day of ovulation - the happiness of motherhood is in your hands.
Obstruction fallopian tubes, endometriosis and progesterone deficiency are the main causes female infertility. The latter pathology is successfully treated today with Duphaston. Hormone deficiency leads to a child or spontaneous abortion. Progesterone causes the growth of the endometrium to stop, making it loose, within which many vessels are formed.
Very soon, these changes will create conditions for the successful attachment of the zygote (fused egg and sperm). Until the placenta is formed, the vessels will provide the embryo with nutrition.
Duphaston is a gestagenic drug containing dydrogesterone, an artificial analogue of natural progesterone, having an identical molecular structure, pharmacological and chemical composition.
When progesterone is not produced naturally enough, with conception and pregnancy up to 10-14 weeks. The medicine replenishes the hormone deficiency without causing serious side effects.
The drug is prescribed to increase hormone levels so that egg implantation becomes possible.
Treatment will be effective when examination of the woman confirms that the cause of infertility is hormonal disorders.
What cures
At the discretion of the doctor, the drug may be prescribed to create optimal conditions with IVF (in vitro fertilization).
Also indications for prescribing are:
The hormone is required for the accumulation of fat in the pregnant woman’s body (she is still breastfeeding a child), relaxation of the muscles of the uterus and intestines.
How to drink
The doctor prescribes the drug treatment regimen individually for each patient; there is no universal advice here. As a rule, therapy begins the day after ovulation. Methods of use and doses are described in detail in the instructions for the drug. If the cause of infertility is endometriosis, the medication is prescribed 3 times a day, 10 mg on days 5-25 of the cycle or regularly.
When conception does not occur due to luteal insufficiency - 10 mg 3 times a day on days 14-25 of the cycle. Treatment cannot be interrupted during 6 cycles; even during the first 2-3 months after conception, Duphaston is not canceled.
Helpful information
Duphaston suppresses the growth of the endometrium, characteristic of the first phase of the menstrual cycle, and normalizes secretion. The mechanism is the same as that of progesterone, but the advantage of the former is that it is used orally, and not by injecting an oil solution.
There is no suppression of female sex hormones. Dydrogesterone ( active substance) is not a derivative of androgens, therefore it does not have properties characteristic of them. There is no risk of weight gain or blood clots.
Dydrogesterone enhances the positive effect of estrogens during menopause without causing negative influence on blood clotting.
The uniqueness of the mechanism of action lies in the fact that the effect of treatment is achieved while maintaining ovulation.
The menstrual cycle does not go astray. Synthetic analogue natural hormone– dydrogesterone reduces the degree of excitability of the myometrium, and the contractile activity of the uterus also decreases.
The effectiveness of Duphaston is reduced when used simultaneously with Rifampicin or Phenobarbital, which affect liver microsomal enzymes. These medications increase the rate of biological transformation of Duphaston. There is no data on drug incompatibility of the drug with other drugs and biological additives.
How to take Ovariamine and Duphaston at the same time
Ovariamin – biologically active additive to food, so the effectiveness of its action is assessed subjectively. Dietary supplements do not work clinical trials, How medications However, in case of infertility, gynecologists advise taking the drug.
