home Calculators Pyobacteriophage - instructions for use, composition and release form, indications, side effects and analogues. Pyobacteriophage complex liquid

Pyobacteriophage - instructions for use, composition and release form, indications, side effects and analogues. Pyobacteriophage complex liquid

Bacteria surround humans everywhere. Their presence or absence can be adjusted using aseptic agents. But they should not be completely destroyed, since the presence of moderately pathogenic flora contributes to the formation of strong and lasting immunity in both adults and children. One of the drugs that contains the most popular bacteriophages is “Piobacteriophage”. Its features and dosage regimen for use in children will be discussed further.

Main characteristics of the drug "Piobacteriophage"

Bacteriophages are drugs based on the use of special viral compounds that destroy the dangerous, pathological bacteriological environment in the human body, but do not have a toxic effect on other vital systems.

"Piobacteriophage" is often prescribed to children, provided that there is laboratory confirmation about the presence of a pathogenic microorganism. Drugs of this kind, according to their characteristics, can work in analogy with all common antibiotics.

Is it possible for children to take the drug?

The drug is indicated for the treatment of children, including newborns.

Indications for use

Most often, doctors prescribe “Piobacteriophage” for diseases of purulent and inflammatory origin that were caused by pathological bacteria. In addition, taking the drug is possible only after a series of laboratory research, which can determine the exact name of the provoking bacteria. Treatment is possible after the recommendation of the attending physician or pediatrician.

Most often, the following diseases with confirmed bacteriological origin are subject to treatment with this remedy:

Lesions of ENT organs.
Spicy and chronic problems inflammatory in nature in the urinary excretory system.
Skin pathologies with a clear inflammatory-purulent component.
Infectious damage to the gastrointestinal tract.
Problems of the organs of vision with a purulent-inflammatory element.

Release forms

The drug "Pibacteriophage" exists in liquid form. The liquid can range from clear to yellowish-green in color. In the pharmaceutical industry, “Piobacteriophage” is produced in the form of a solution packaged in vials and ampoules. The first option can be found in containers of 10, 15, 20 and 25 ml. Bottles are packed 4 pieces per carton boxes with special protective partitions. Ampoule packaging can be in a 5-10 ml format, in a cardboard package of 5-10 pieces.

Instructions for use

"Pyobacteriophage" has application in pediatric practice, so there is next norm drug, according to age criteria:

For children aged from birth to 6 months, 10 ml of the drug is indicated in a single dosage.
For children from 6-12 months, 10-20 ml of the drug per dose is indicated.
For babies aged 1-3 years, 15-30 ml per dose is recommended.
For children aged 3-8 years, 20-40 ml is indicated.
For children over 8 years of age and adults, a single dose of the drug is 50 ml.

The regimen for taking the drug depends on the type of disease and its extent, so the doctor sets the norm in a face-to-face consultation and has full control over the patient’s treatment. The medication can be taken in the form of lotions when skin lesions, For urological diseases oral administration.

It is important to treat the surface with sodium chloride before washing. The duration of the course is on average 10-14 days and depends on the doctor’s prescriptions. Infants are advised to administer the drug in the form of enemas 2 times a day for 5 days. Before your appointment, you must consult a doctor!

Compound

Lysed cultures:

Side effects and contraindications

As a rule, the drug is well tolerated and has no negative side effects. Due to its relative safety, the use of the drug is permitted in any case.

Analogs

Analogue drugs include “Piopolyfag”, “Sextafag”.

Price range

You can purchase “Piobacteriophage” at a pharmacy for the price from 650 to 850 rub. per package.

If a patient is diagnosed with a bacterial infection, an antibiotic is often prescribed, but in the treatment of those caused pathogenic bacteria Viruses called phages can also be used to treat pathologies.

With their help, drugs are created with a selective effect on certain microorganisms. They contain bacterial phagolysates, that is, purified microbial cells destroyed by phages. One of these drugs is Piobacteriophages. They are often included in the treatment complex purulent infections, including in children.

Release form and composition

"Piobacteriophages" are produced Russian company Microgen, which also produces other immunobiological drugs.

Currently, the bacteriophage with the prefix “pio” is represented by two means:

“Complex pyobacteriophage”;
"Pyobacteriophage polyvalent Sextaphage."

Both drugs are solutions packaged in sterile glass bottles of 20 ml. “Complex Pyobacteriophage” is sold in 8 such bottles in a pack, and is also additionally available in larger packaging (100 ml bottles, which are sold in 1 piece). “Sextaphage” is presented in packs of 4 and 10 bottles. The solution itself is transparent, yellowish or greenish.

The main difference between these two drugs is their composition, in particular, the list of microbes destroyed by bacteriophages, which are the active ingredient of the solution.

“Sextaphage,” as the name suggests, contains 6 types of microorganisms:

streptococcus

staphylococcus

Escherichia coli

Pseudomonas aeruginosa

They are also present in Pyobacteriophage Complex, but this medicine additionally contains destroyed enterococci and Klebsiella oxytoca. An auxiliary component of both drugs is 8-hydroxyquinoline sulfate (preservative). The effect of such drugs on the body, indications for their use and even dosages are the same, so the information below will concern both drugs.

enterococci

Klebsiella oxytoca

Operating principle

The microbes destroyed by phages that are in the “Piobacteriophage” contribute to the destruction of precisely those species and strains of bacteria from which they were obtained.

This means that “Sextaphage” affects streptococci and staphylococci, two types of Proteus and Klebsiella pneumoniae, as well as Escherichia coli and Pseudomonas aeruginosa. “Complex Pyobacteriophage” is also effective against enterococci and Klebsiella oxytoca.

Indications

The reason to prescribe “Piobacteriophage” may be:

otitis media, bronchitis, tonsillitis, rhinitis, tracheitis, sinusitis and other infections of the respiratory system;
boil, felon, abscess and others bacterial infections skin, bones and soft tissues;
purulent complications from skin damage (burns, wounds, etc.);
cystitis, urethritis and other bacterial infections of the urogenital organs;
purulent eye infections;
dysbacteriosis;
intestinal infection;
generalized bacterial infections and so on.

The prophylactic use of solutions is in demand for external treatment of skin lesions and sutures after operations. In addition, drugs are prescribed to prevent hospital-acquired infections if such a risk exists.

At what age is it prescribed?

Pyobacteriophage can be used in children at any age. This medication is used even in newborns, for example, for sepsis, pyoderma, conjunctivitis or omphalitis.

However, the drug must be prescribed by a doctor after determining the sensitivity of the pathogen.

Contraindications

Treatment with Pyobacteriophage is prohibited if the patient is hypersensitive to any component of the solution. There are no other contraindications for such medications.

Side effects

According to information from the manufacturer, Piobacteriophage does not cause any side effects. However, in in rare cases after taking the solution, you may experience skin rash or diarrhea, and in infants in the first months of life, regurgitation may occur. About these negative symptoms You should immediately tell your doctor.

Instructions for use

To obtain the desired effect, it is important to follow some rules for using Piobacteriophage.

Since the medicine is stored in the refrigerator, before giving it to the baby, you should warm up the solution a little by holding the syringe in your hands or drawing up the medicine for some time (no more than 1 hour).
Before use, the solution must be shaken and its transparency checked. If cloudy, the medication should be thrown away. To prevent other microbes from getting inside the bottle, it is best to draw the drug with a syringe, and wipe the stopper and hands with alcohol.
Most often, “Piobacteriophage” is used internally. The product is given to the child three or four times a day 1 hour before feedings. The duration of oral administration ranges from one week to 20 days - the duration of treatment for a particular patient is determined by the doctor.
If the drug is prescribed to a newborn, then the required dose of the solution is diluted boiled water 1:2. In the absence negative reactions and good tolerance, after a few days the product can be given undiluted. If the baby refuses to drink "Piobacteriophage" in pure form, it is permissible to add a little mother’s milk to the medicine.

In addition to oral administration, the drug is often used in the form of enemas. This method is prescribed to children with enterocolitis, vomiting, regurgitation, sepsis and other problems. Rectal administration of the solution involves performing a high enema (it is performed through a catheter or using a gas outlet tube). The duration of such treatment is usually 7-10 days.
“Piobacteriophages” are also used externally, for example, to make lotions for suppuration of an umbilical wound or to irrigate burnt skin. If the conjunctiva is damaged, the drug is dripped into the eyes, for rhinitis and adenoids - into the nose, and for stomatitis and throat lesions, rinses and inhalations are prescribed. Surgeons, if necessary, inject such drugs into cavities, for example, inside a joint or into the pleural cavity.
To determine a single dosage, it is important to know the patient’s age. The recommended dose both for oral administration and for administration into the rectum is noted in the table in the instructions for “Piobacteriophages”. For example, infants up to 6 months should be given 5 ml of medication orally, and 10 ml of solution should be used for an enema.
For prophylactic use, age-specific dosages are used, but the medicine is given only once a day. The duration of such an appointment should be checked with the doctor for each patient separately.

Many patients are categorically opposed to antibiotics, but there are clinical situations in which representatives of this pharmacological group simply cannot be avoided. Common medical drug- Polyvalent pyobacteriophage, which is available in the form of a medicinal solution, is taken orally, externally and locally.

General description of the drug

After processing cultures of bacteria such as Escherichia coli, streptococcus, staphylococcus, Proteus, enterococcus and others, a medical product called Pyobacteriophage polyvalent was developed. Essentially, this is a mixture of bacteriophages necessary for productive suppression of the activity of pathogenic flora. The medicine is presented medicinal solution yellow, transparent or greenish in color.

Because this medicinal product is chemical composition a mixture of bacteriophages, in practice has a wide spectrum of action, i.e. active against a number of colonies of harmful microorganisms. This is the most safe method treatment, since the active components of the drug do not interact with body cells and beneficial bacteria.

According to their own pharmacological properties it is immunostimulating and antibacterial agent, which demonstrates a gentle but targeted effect directly on the foci of pathology. Pyobacteriophage polyvalent does not have complete analogues in modern pharmacology, list of contraindications and side effects minimum. You can buy it at a pharmacy, without a prescription.

Indications for use

The use of this medication is appropriate for inflammatory, purulent, infectious processes when the cause of the pathology is increased activity streptococci, staphylococci, enterococci, coli, proteus More often, doctors recommend this antibacterial drug in the following clinical situations:

surgical infections (peritonitis, suppuration of open wounds, pleurisy, mastitis);
extensive damage to the gastrointestinal tract (dysbacteriosis, pancreatitis, cholecystitis);
urogenital infections (colpitis, vulvitis, cystitis);
purulent-inflammatory pathologies of ENT practice (frontal sinusitis, tonsillitis, sinusitis);
prevention of intrauterine infections;
ophthalmology diseases infectious nature(keratoconjunctivitis, conjunctivitis, purulent corneal ulcer).

The use of this medication should not be unauthorized; only the attending physician can determine the daily dose, method of use of the antibiotic, duration intensive care. Superficial self-medication can only aggravate the clinical picture and provoke complications.

Contraindications for use

Despite the fact that Pyobacteriophage polyvalent belongs to the group of antibiotic drugs, its use is permitted for all categories of patients, from newborn children to retired people. Medical contraindications are absent in full, moreover, increased sensitivity body to active components completely excluded. Pregnant women, young mothers during breastfeeding- not an exception. Such categories of patients can also receive such a prescription from the attending physician.

Side effects and cases of overdose

During intensive therapy, the occurrence of side effects is excluded, and cases of overdose have not been recorded at all in extensive research. medical practice. Pyobacteriophage polyvalent is an absolutely safe medical drug; moreover, it can be safely combined in one treatment regimen with other antibiotic agents.

Directions for use and daily doses

This medication differs in several ways of delivering the medicine to a weakened body. These are applications, compresses, irrigation of the mucous membrane, oral administration, performing enemas, draining internal cavities. Which method of application is suitable for a specific clinical picture is determined by the attending physician. In addition, he prescribes daily doses and specifies the time frame for the course of antibacterial therapy. So:

It is important to know not only the dose, but also the method of using the medicine. For example, before opening the bottle you need to shake it well, and then observe the color of the medicine. If a cloudy sediment appears or the liquid is not clear enough, it is better to check the expiration date of the antibiotic and temporarily stop taking it. If the medicine is suitable for use, the rules for its use are as follows:

Wash your hands before using Pyobacteriophage polyvalent liquid.
For repeated use, it is recommended to treat the rubber stopper of the bottle with alcohol to prevent the indicated antibiotic from becoming unusable.
If the drug is used repeatedly, it should only be stored in the refrigerator.
When using relatively small doses of the medicine, take the dose exclusively with a sterile syringe.
Do not leave the bottle open.

If you follow the above rules, you can use an opened bottle of Pyobacteriophage polyvalent throughout the entire shelf life.

special instructions

Since this is an antibiotic, it is important to coordinate its prescription with a local physician (pediatrician) or other highly specialized specialist. The drug Pyobacteriophage polyvalent can be an independent treatment agent, or be part of complex therapy with representatives of other pharmacological groups. Drug interactions absent.

The medication is available without a prescription; moreover, it is approved for use by premature babies under conditions of mandatory hospitalization. The child can learn about this antibiotic in the prenatal period, when the need arises. urgent treatment pregnant woman.

Data on the compatibility of polyvalent Pyobacteriophage and alcohol are completely absent. It is also known that this combination antibiotic does not reduce the patient’s concentration and does not affect the quality of management vehicle during the period of antibacterial therapy.

A medical product has several varieties of one treatment agent. In this case we're talking about about Pyobacteriophage polyvalent, purified, staphylococcal and Sextaphage. The specific name depends on the characteristics of the clinical picture and the intended method of using the antibiotic.

It remains only to add that reviews of this treatment are positive. Doctors prescribe polyvalent Pyobacteriophage for inflammatory and infectious processes, without fearing for the health of a weakened organism. So, at the first symptoms from the list of indications, you should definitely pay attention to this natural antibiotic.

Rate Pyobacteriophage polyvalent: instructions!

Latin name:
Pyobacteriophagum Polyvalentum
ATX code: V03A
Active substance: Pyobacteriophage
Manufacturer: Microgen NPO, Russia
Conditions for dispensing from a pharmacy: Over the counter
Price: from 700 to 800 rub.

Pyobacteriophage polyvalent purified (Sextaphage) – medicine, is used therapeutically and prophylactically for infections that are accompanied by purulent and inflammatory processes. It belongs to the category of antibacterial and immunostimulating drugs with a wide range of effects. Contains a mixture of bacteriophages.

Indications for use

Sextaphage is used in medical practice when curing pathologies caused by staphylococci, streptococci, Proteus, E. coli and others. Most often prescribed for the following ailments:

ENT pathologies and respiratory diseases (pharyngitis, pneumonia, bronchitis, inflammatory process of the middle ear)
Wounds purulent in nature, burns, various types of boils, abscess
Urological infectious diseases
Conjunctivitis, purulent ulcers on the cornea resulting from trauma
Generalized septic pathologies
Diseases caused by intestinal viruses
Purulent pathologies accompanied by inflammation in newborns.

For severe infectious diseases, which arose against the background of the above bacteria, purified polyvalent Pyobacteriophage is prescribed in combination with other medications.

In addition to therapy, it is appropriate to use Sextaphage in for preventive purposes when treating wounds in the postoperative period.

Compound

Purified polyvalent pyobacteriophage includes the following main components: a mixture of phagolysate of staphylococci, streptococci, Escherichia coli, Protea, Pseudomonas aeruginosis and Klebsiella pneumoniae. Additional ingredient: preservative 8-hydroxyquinoline sulfate monohydrate.

Medicinal properties

Pyobacteriophage polyvalent purified has harmful effects for microorganisms such as staphylococci, streptococci, E. coli and some others. Characterized by anti-inflammatory and antibacterial effects.

The average price is from 700 to 800 rubles.

Release forms

Purified polyvalent pyobacteriophage (Sextaphage) is a light liquid with a yellowish or greenish tint. Produced in 20 ml glass bottles. One package contains 4 bottles. Sextaphage is also offered in ampoules of 10 ml and 5 ml.

Mode of application

Purified polyvalent Pyobacteriophog is prescribed for internal use, and is also used topically and for intracavitary administration. Used locally as compresses, irrigations, and for treating wounds. Intracavitary injection is indicated in the area of the nasal sinuses, bladder, vagina, etc. The medicine is also prescribed orally, sometimes administered using a probe, or enemas.

Depending on the nature of the disease, the dosage may vary, recommended doses:

For children up to six months, a single dose is 5 ml, for rectal administration - 10 ml. For babies up to one year - 10 ml and 20 ml for rectal administration. For children under 3 years of age, the recommended dose is 15 ml internally and 20 ml by enema. Children under 8 years of age should be given 20 ml internally and 30-40 ml rectally
A single dose for adults and adolescents is 20-30 ml orally and 40 ml for rectal use. The duration of the therapeutic course is determined by a specialist
During the healing purulent inflammation the drug is prescribed locally as a lotion. For abscesses, it is injected into the affected cavity after removing the suppuration.
In case of bronchitis or pneumonia, the medicine should be taken 10-20 ml internally 3 times a day. It is also recommended for inhalation. Duration of therapy is 15-20 days. For sore throat and pharyngitis this solution used for rinsing 10 ml 2-3 times a day, week
For urological infections, Sectafag is injected into the bladder cavity in an amount of 15-20 ml
For ophthalmic diseases, the medication is prescribed orally, as well as drops 4-5 times a day.
At various infections intestinal polyvalent purified Pyobacteriophage is taken orally 1-2 hours before meals for one week or administered via enema.

During pregnancy and breastfeeding

When treating infectious diseases for women while pregnant and breastfeeding, purified polyvalent Pyobacteriophage can be used only as prescribed by a doctor.

Contraindications and precautions

The solution has practically no restrictions, the only one being individual intolerance to its components.

It is necessary to open purified polyvalent Pyobacteriophage (Sextaphage) by adhering to all antiseptic rules. Before use, the medication should be shaken well; if the liquid is clear, then this drug is approved for use. You must remember that if there is cloudiness, it is prohibited to use the medicine!

It is not advisable to leave the printed bottle open; it should be stored in a cool place. When it is necessary to use a small dosage, it is best to use a sterile syringe, which is used to draw the solution from the container.

Cross-drug interactions

Sextaphage is approved for use with other antibacterial and anti-inflammatory medications.

Side effects

To date, adverse reactions are unknown.

Conditions and shelf life

The medicine must be stored in a dry and dark place, when temperature conditions 2-8 degrees Celsius. The shelf life is 2 years.

Analogs

Pibacteriophage complex liquid

Microgen NPO, Russia
Price from 800 to 900 rub.

Pyobacteriophage complex liquid is prescribed for the treatment of infections accompanying purulent and inflammatory processes. It has an antibacterial effect against many microorganisms. The difference between the complex Pyobacteriophage and the polyvalent one is that the polyvalent one does not contain enterococcus phagolysate. Pyobacteriophage complex liquid is offered in the form of a solution.

pros

Practically does not cause adverse reactions
Approved in pediatrics

Minuses

Not a very pleasant taste
Quite a high cost.

Microgen NPO, Russia
Price from 700 to 800 rub.

Staphylococcal bacteriophage is often contained in the combined Pyobacteriophage or can be produced independently. Staphylococcal Sextaphage contains bacteriophages that can only kill staphylococci. Used for diseases caused by these microorganisms.

pros

Can be used for internal use, both externally
Does not have a detrimental effect on other organs, unlike antibiotics

Minuses

Narrow spectrum of action
It is advisable not to use for a long period.

Microgen NPO, Russia
Price from 700 to 750 rub.

Streptococcal bacteriophage is a drug that is effective against streptococci. It is used in pulmonology, otolaryngology, in the treatment of urological, enteral and some other infections.

pros

Does not change intestinal microflora
Can be prescribed to children

Minuses

Difficult to access - not available in all pharmacies.

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"Pyobacteriophage"

Unfortunately, inflammatory diseases bacterial origin can hardly be considered a rarity. Every person faces similar problems from time to time, regardless of age, gender or other indicators. So what treatments does modern medicine offer for treating such ailments?

Today, drugs based on bacteriophages are becoming increasingly popular. And quite often doctors prescribe to their patients medicine"Pyobacteriophage". The instructions for using it are quite simple, but it really does have an effect. But what is special about this drug? What does it contain? Are there any contraindications to therapy? This information will be of interest to many readers.

Description of the composition and release form of the drug

The drug “Pyobacteriophage complex liquid” is available in the form of a transparent yellowish solution. The liquid is placed in glass bottles with a capacity of 20 or 100 ml.

This drug is a mixture of bacteriophages that are obtained by lysis of bacterial cells. In particular, the solution contains bacteriophages that are active against enterococci, staphylococci, streptococci, Klebsiella, Escherichia coli, Pseudomonas and Proteus. The resulting lysate is carefully filtered to remove pathogenic cell residues during the production process. Quinosol is used as a supporting buffer. By the way, the solution should be stored at a temperature of 2-8 degrees Celsius.

What properties does the drug have?

What effect can the drug “Piobacteriophage” provide? The instructions say that the medicine copes well with various kinds infections. But why?

In fact, such drugs have unique properties. Bacteriophages are types of viruses that infect bacterial cells. Penetrating through the cell wall, the virus begins to actively multiply, using cellular resources for this. This, in turn, leads to the death of bacteria, lysis of their walls and the release of new viral particles.

It is also worth noting that the action of bacteriophages is highly specific. Viral particles infect only certain bacterial cells, without affecting either the structures of the body or the beneficial bacteria which are necessary to maintain normal functioning organ systems.

Indications for use

In what cases are patients prescribed the drug “Piobacteriophage”? The use of this tool is quite widespread. It is used for treatment inflammatory diseases caused by the activity of phage-sensitive bacteria.

For example, medication is indicated for intestinal infections. In surgical practice, the drug is used to treat suppurations, burns, carbuncles, phlegmons, and boils. Also indications for use are infectious sore throats, otitis, pharyngitis, sinusitis, pleurisy, pneumonia, pyelonephritis, cystitis, colpitis, salpingo-oophoritis, etc.

The drug "Piobacteriophage": instructions for use

Only a doctor can prescribe use this drug. The specialist will also determine the maximum effective dose and duration of therapy. So how to use the Piobacteriophage product correctly? The instructions in this case depend on the form of the disease, the patient’s condition and some other factors.

For example, for skin lesions, the solution is used in the form of wet dressings, applications, irrigations, lotions, etc.
When treating an abscess, a solution with bacteriophages is injected directly into the suppuration cavity, having previously thoroughly cleaned it of existing purulent masses.
For diseases excretory system the solution can be injected directly into the renal pelvis or into the bladder cavity.
The drug can also be used for instillation, washing, gargling (for example, throat), irrigation.
For intestinal diseases, enemas based on this solution will be effective.
However, the drug is most often prescribed orally. In addition, for some diseases it is advisable to combine several methods of administration at once to achieve maximum results.

The single dose is determined by the doctor. For adult patients and children over eight years of age, it is usually 50 ml. You need to take the drug three times a day (the number of doses may be reduced if therapy includes other procedures, such as enemas). The course of treatment in most cases lasts from 5 to 15 days. If we are talking about the prevention of a particular disease, then a seven-day intake will be enough.

Features of treatment of children under 6 months of age

Of course, this drug is widely used in pediatrics for the treatment of newborns and children in the first months of life. Treatment with “Pyobacteriophage” in this case has some features that are worth paying attention to.

When treating enterocolitis or sepsis in newborns (including premature babies), the method of so-called high enemas is used. Used for intestinal irrigation special catheters. A single dose of enema medication is 10 ml, the procedure is repeated 2-3 times a day. If there is no vomiting, then the child can be given the solution orally, mixed with formula or breast milk- a single dose is 5 ml. Quite often, doctors recommend combining rectal and oral methods administration of the drug. The course of therapy usually lasts from 5 to 15 days.

Are there any contraindications and side effects?

Of course, many people are interested in the question of whether all categories of patients are allowed to take the drug “Piobacteriophage”? The instructions state that this product has no contraindications. Moreover, no cases of severe adverse reactions have been reported. Sometimes patients experience slight allergic reaction, but this happens extremely rarely.

The drug “Pyobacteriophage complex liquid” is often used to treat even newborns. Moreover, the drug is indispensable in the treatment of certain infections during pregnancy, because during this period of a woman’s life traditional antibacterial therapy using antibiotics can only cause harm.

But, despite all the safety, you should not use the medicine without permission - be sure to consult your doctor before starting therapy.

How much does the medicine cost?

For many patients, the issue of cost of a particular medicine is important. So how much will the drug “Piobacteriophage” cost? The price, of course, may fluctuate depending on the volume you purchase, the manufacturer, as well as the financial policy of the pharmacy.

On average, a package costs 900 rubles. But you need to keep in mind that to complete the full course of treatment you will most likely need several of these packages.

What to do if, for one reason or another, you cannot use the “Complex Liquid Pyobacteriophage”? The bacteriophage is also contained in some other drugs - if necessary, you can choose a substitute with almost the same properties. For example, good analogues such means as “Piobacteriophage polyvalent purified”, “Piopolyphage”, “Sextaphage” and some others are considered.

The drug "Piobacteriophage": reviews from doctors and patients

Today, drugs based on bacteriophages are becoming more and more popular. After all, standard therapy with antibiotics is not suitable for everyone and is often associated with side effects. And in such cases, doctors prescribe the drug “Piobacteriophage”. Reviews from doctors are positive character, since the drug copes excellently with its main task.

Patients also respond well to this means. It helps to cope with staphylococcus and other pathogenic microorganisms, does not harm health and has practically no contraindications. As for the negative aspects, it is worth mentioning the price, which may be too high for some patients. The disadvantages include a not very pleasant taste, as well as some difficulties that arise with storing the drug. But in any case, health is worth all the inconvenience.

www.syl.ru

PYOBACTERIOPHAGE POLYVALENT PURIFIED

Before use, the vial with the bacteriophage must be shaken and inspected. The preparation must be transparent and free of sediment.

Attention! If cloudy, do not use the drug!

Due to the content of the preparation in a nutrient medium in which bacteria from environment causing cloudiness of the drug, the following rules must be observed when opening the bottle:

Wash your hands thoroughly;

Treat the cap with an alcohol-containing solution; remove the cap without opening the stopper;

Don't put the cork in inner surface on a table or other objects;

Do not leave the bottle open;

Store an opened bottle only in the refrigerator.

When using small doses (2-8 drops), the drug must be taken with a sterile syringe in a volume of 0.5-1 ml.

The drug from an opened bottle, subject to storage conditions, the above rules and the absence of turbidity, can be used throughout the shelf life.

The drug is used for oral administration (orally), in the form of enemas, applications, irrigations, injection into wound cavities, vagina, uterus, nose, sinuses, as well as into drained cavities: abscesses, abdominal, pleural, bladder, renal pelvis.

The drug is taken orally on an empty stomach 0.5-1 hour before meals.

Treatment of purulent-inflammatory diseases with localized lesions should be carried out simultaneously both locally and by taking the drug orally.

If the cavity of a purulent lesion is treated with chemical antiseptics, before using the bacteriophage, it must be washed with a sterile 0.9% sodium chloride solution.

When treating tonsillitis, pharyngitis, laryngitis, the drug is used to rinse the mouth and throat 3 times a day, 10-20 ml, the course of treatment is 7-10 days.

When treating bronchitis and pneumonia, the drug is taken orally 3 times a day, 10-20 ml, and is also used in the form of aerosols and inhalations (without heating and the use of ultrasound), the course of treatment is 15-20 days.

In the treatment of otitis, the drug is used for washing and introducing 2-5 ml into the middle ear cavity 1-3 times a day. The course of treatment is 7-15 days.

When treating inflammation of the sinuses, the drug is used to rinse the nasal cavity, nasopharynx and sinuses in a dose of 5-10 ml and inject 2-3 ml into the sinuses. The procedure is repeated once daily for 7-10 days. In addition, the drug is administered into the nasal cavity in the form of turundas moistened with bacteriophage, in turn into each nasal passage and left for 0.5-1 hour. The procedure is repeated 3 times a day, the course of treatment is 7-15 days.

In the treatment of stomatitis and chronic periodontitis, the drug is used in the form of rinses in the mouth 3-4 times a day in a dose of 10-20 ml, as well as by introducing turundas impregnated with bacteriophage into the periodontal pockets for 5-10 minutes, the course of treatment is 7-10 days.

For conjunctivitis and keratoconjunctivitis, the drug is used 2-3 drops 4-5 times a day, the course of treatment is 5-7 days; at purulent ulcer corneas - 4-5 drops per day for 7-10 days, for purulent iridocyclitis - 6-8 drops every 3 hours in combination with oral administration in therapeutic dosages for 7-10 days.

In case of an abscess, after opening and removing the purulent contents, the drug is administered in an amount less than the volume of removed pus once daily, the course of treatment is 7-10 days.

For peritonitis and pleurisy, the drug is administered into the drained cavities - abdominal and pleural through drainage tubes - 20-70 ml once daily, the course of treatment is 10-15 days.

For osteomyelitis, the drug is administered into the wound cavity through turundas and drainages in the amount of 10-30 ml once daily, the course of treatment is 15-20 days.

In the treatment of mastitis, suppuration of wounds and burns, the drug is used in the form of irrigation, applications, dressings, injection into drainage in a dose of 5-50 ml depending on the lesion at least 1 time per day, the course of treatment is 10-15 days.

In the treatment of purulent-inflammatory gynecological diseases(suppuration of wounds, endometritis, vulvitis, bartholinitis, colpitis, salpingoophoritis) the drug is used for irrigation, applications, injected into the cavities of wounds, vagina, uterus, 5-20 ml once a day for 7-10 days.

For cystitis, pyelonephritis, urethritis, the drug is taken orally in therapeutic dose 3 times a day 1 hour before meals for 10-20 days. If the cavity of the bladder or renal pelvis is drained, the drug is administered through a cystostomy or nephrostomy 1-3 times a day, 20-50 ml per bladder and 5-7 ml per renal pelvis, course of treatment is 7-15 days.

For gastroenterocolitis, pancreatitis, cholecystitis, as well as intestinal dysbiosis, the bacteriophage is taken orally age dosages 3 times a day 1 hour before meals for 7-15 days (according to clinical indications). For indomitable vomiting, the drug is used in the form of high enemas 2-3 times a day, 20-40 ml. In case of intestinal dysbiosis, the drug can be used with normal flora preparations.

For the prevention of nosocomial surgical infections the drug is used for the treatment of postoperative and fresh infected wounds in a dose of 5-50 ml depending on the lesion, once daily for 5-7 days.

Use of the drug in children under 1 year of age (including premature infants)

For gastroenterocolitis, pneumonia and sepsis of newborns, the drug is used by mouth 2-3 times a day, 3-5 ml, 30 minutes before feeding. In cases of indomitable vomiting, the drug is used in the form of high enemas (through a gas outlet tube or catheter) once daily in a dose of 5-10 ml. A combination of rectal (in the form of high enemas) and oral administration drug. The course of treatment is 7-15 days (according to clinical indications). In case of recurrent course of the disease, repeated courses of treatment are possible.

In the treatment of omphalitis, pyoderma, infected wounds, the bacteriophage is used in the form of applications of 5-10 ml 2-3 times a day (a gauze cloth is moistened with the bacteriophage and applied to umbilical wound or affected area of skin) for 7-15 days.

In order to prevent the occurrence of nosocomial infection in newborns, the bacteriophage is used according to epidemic indications orally 3-5 ml 3 times a day 30 minutes before feeding during the entire period of hospital stay.

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Polyvalent Pyobacteriophage

Compound

The drug contains active substance pyobacteriophage (mixture of filtrates of sterile phagolysates, streptococci, Proteus, Pseudomonas aeruginosa, staphylococci, enterococci, Klebsiella, Escherichia coli) 10 ml per bottle.

The drug also contains Excipients– preservatives.

Release form

Solution in a bottle of 20 ml, ampoules of 10 and 5 ml. There are 4 bottles in a cardboard package, ampoules - 5 or 10 pieces.

pharmachologic effect

Antibacterial, immunostimulating agent.

Pharmacodynamics and pharmacokinetics

The drug specifically lyses bacteria Proteus, streptococci, staphylococci, Klebsiella pneumoniae, Pseudomonas aeruginosa, various serogroups of Escherichia coli. Thus, providing an immunostimulating effect on the body.

Indications for use

Liquid Pyobacteriophage is prescribed:

for the treatment and prevention of purulent, inflammatory, gastrointestinal diseases;
with peritonitis, pleurisy, osteomyelitis, mastitis, purulent wounds and skin lesions;
for the treatment of sore throats, stomatitis, otitis, sinusitis, pleurisy and pneumonia;
for pancreatitis, gastroenterocolitis, cholecystitis, dysbacteriosis;
for the treatment of cystitis, endometritis, colpitis, pyelonephritis;
with suppuration of the cornea, conjunctivitis;
for omphalitis, pyoderma, enteritis, various dysbacteriosis, septicemia, septicopyemia.

Contraindications

Doesn't have it.

Side effects

Not registered.

Instructions for Pyobacteriophage Polyvalent purified (Method and dosage)

According to the instructions for use of Pyobacteriophage Polyvalent, enemas, lotions and irrigations are made with the drug. It is also possible to use the drug intracavitary and orally.

Frequency of application 1-3 times a day. The course usually lasts from 5 to 15 days.

For the treatment of pyelonephritis, 5-20 ml are prescribed orally, in 3 doses.

How to give it to a child?

If uncontrollable vomiting occurs in children under one year of age, you can additionally administer the drug through a tube, 3-5 ml every day. The course lasts 5-7 days.

For the treatment of omphalitis and pyoderma in newborns, the medicine can be used in the form of applications, twice a day. The course of piopolyvalent bacteriophage ranges from 5 days to a week.

Overdose

No cases of overdose have been reported.

Interaction

In parallel with treatment with the drug, other anti-inflammatory and antibacterial agents can be used.

Terms of sale

No recipe needed.

Storage conditions

Temperature from 2 to 8 degrees. The shelf life at temperatures up to 25 degrees is reduced to one month. Use immediately after opening. If flakes appear, the solution is not homogeneous, or after the expiration date, the Bacteriophage cannot be used.

Best before date

24 months.

Analogs

Analogues: Piobacteriophage, Piobacteriophage Complex liquid, Piopolyphage, Sextaphage.

Complex Bacteriophage and Polyvalent Pyobacteriophage

The only difference between Complex Pyobacteriophage and Polyvalent is that the latter does not contain enterococcus phagolysate. The drugs have a common manufacturer.

Reviews for Pyobacteriophage Polyvalent purified

Reviews from doctors are good. It is also used by surgeons for postoperative treatment wounds, and pediatricians, and gynecologists with urologists. Some believe that the drug is more effective and safe to use than antibiotics.

The reviews on the forums are very good. Many have used the drug and were satisfied with the results. Bacteriophage is especially effective for children due to the absence of side effects; newborns are often allergic to antibiotics.

Price of Polyvalent Pyobacteriophage, where to buy

The price of Pyobacteriophage Polyvalent purified in Ufa is about 650 rubles.

You can buy the product in Moscow for 700 rubles, for 4 ampoules of 20 ml each. Sometimes the product may be called PIOpolyvalent Bacteriophage.

NOTE! Information about medications on the site is for reference and general information, collected from publicly available sources and cannot serve as a basis for making a decision on the use of medications in the course of treatment. Before use medicinal product Polyvalent Pyobacteriophage, be sure to consult with your doctor.

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Complex bacteriophage: instructions for use, analogues and reviews

Diseases bacterial etiology most often treated with antibacterial drugs who have wide range actions. To selectively destroy pathogenic agents, it is recommended to use bacteriophages. Such drugs have many advantages compared to other medications. A complex bacteriophage is a medicine that contains several types of bacteriophages. Let's take a closer look at the mechanism of action and scope of application of this medicine.

What are bacteriophages?

Every ailment needs specific treatment. To choose the right method of therapy, it is important to determine the type of pathogen. To combat bacterial pathologies that are characterized by severe course and consequences, doctors often prescribe bacteriophages. These drugs are useful for human body viruses that use harmful bacteria to reproduce and continue their life activity. At the same time they provide negative impact only on pathogenic microorganisms and do not affect the functioning of organs and systems.

Unlike antibiotics, bacteriophages do not destroy beneficial microflora and do not cause the development of dysbacteriosis. The drugs can be taken on a long-term basis and without fear of the emergence of resistance pathogenic microorganisms to the active ingredients.

In pediatric practice, polyvalent bacteriophage is often used. Reviews (for children the medicine is prescribed after diagnosis) from specialists confirm the effectiveness of the drug, provided that the type of pathogen is accurately determined. To do this, before starting therapy, you must undergo laboratory diagnostics. Bacteriophages are considered to be as powerful drugs as antibiotics.