home Audience 4 Citramon during breastfeeding: harm and alternative remedies. Excessive dose of caffeine. Who should not take Citramon

Citramon during breastfeeding: harm and alternative remedies. Excessive dose of caffeine. Who should not take Citramon

Citramon-F(Citramonum-F)

Basic physical and chemical characteristics: dot tablets of light brown color, with the smell of cocoa;

Compound. 1 tablet contains acetylsalicylic acid 0.24 g, paracetamol - 0.18 g, caffeine 0.03 g;

other ingredients: potato starch, low molecular weight medical polyvinylpyrrolidone, calcium stearate, citric acid, cocoa.

Release form of the medicine. Pills.

Pharmacotherapeutic group. Analgesics and antipyretics. ATC code N02B A51.

Action of the medicine.

Pharmacodynamics. Due to the presence of acetylsalicylic acid and paracetamol in the tablet, the drug has anti-inflammatory, antipyretic and analgesic effects.

Acetylsalicylic acid causes antipyretic and anti-inflammatory effects, relieves pain, inhibits platelet aggregation, and improves microcirculation in the inflammation zone.

Paracetamol causes analgesic and antipyretic effects.

Caffeine helps normalize cerebral vascular tone and accelerates blood flow, without exhibiting a significant stimulating effect on the central nervous system at this dose.

Pharmacokinetics. Acetylsalicylic acid, when administered orally, is quickly absorbed, sufficient concentration in the blood is observed after 30 minutes, the maximum after 2 hours. Part of the drug is absorbed in the stomach, most of- V small intestine.

Paracetamol is well absorbed in the upper sections gastrointestinal tract, metabolized in the liver. Maximum therapeutic effect develops in 2 – 2.5 hours. Half-life is about 2 hours. It is excreted from the body in urine after 4 – 4.5 hours.

Caffeine increases gastric secretion. The mechanism of action of caffeine is due to the inhibition of the enzyme phosphodiesterase, which leads to the accumulation of cyclic adenosine monophosphate inside cells. Cyclic AMP stimulates metabolism in organs and tissues, including muscles and the central nervous system.

The components of the drug and metabolic products are excreted from the body through the kidneys.

Indications for use. Mild or moderate pain syndrome, predominantly of inflammatory origin (frontal sinusitis, sinusitis), as well as antipyretic drug in febrile conditions of various etiologies. How symptomatic remedy for diseases accompanied by pain and hyperthermia: migraine, headache, toothache, neuralgia, myalgia, arthralgia, primary dysmenorrhea, including colds - flu, acute respiratory viral infections.

Method of use and dose. Citramon-F is used orally, preferably after a meal. Adults are prescribed 1–2 tablets 2–3 times a day. Maximum daily dose makes 6 tablets. The course of treatment depends on the effectiveness of therapy and, as a rule, does not exceed 7 days. It is also prescribed once to relieve pain.

Side effect. May be observed side effects that are typical for acetylsalicylic acid preparations: nausea, anorexia, pain in the epigastric region, diarrhea, erosive and ulcerative lesions of the stomach and intestines, thrombocytopenia, anemia, allergic reactions, dysfunction of the liver and kidneys. At long-term use Dizziness, headache, reversible visual impairment, tinnitus, vomiting, impaired rheological properties and hematopoiesis.

Paracetamol preparations are characterized by allergic reactions; with long-term use, hepatotoxicity and nephrotoxicity are not excluded. toxic effect drug, anemia, methemoglobinemia.

Contraindications. Citramon-F is contraindicated in severe liver and kidney dysfunction, arterial hypertension, decreased blood clotting, stomach ulcers and duodenum, individual intolerance to the components of the drug, as well as during pregnancy and lactation.

Overdose.

Symptoms: nausea, vomiting, tinnitus, general malaise, fever. More severe symptoms characterized by the development of stupor, the appearance of convulsions, the development of coma, pulmonary edema, renal failure.

Treatment: induction of vomiting, administration of activated charcoal and laxatives, alkalization of urine (intravenous infusion of sodium bicarbonate), for pulmonary edema - artificial ventilation lungs with a mixture that is enriched with oxygen; To treat cerebral edema, hyperventilation or osmotic diuresis is used.

Features of use. Use with caution to treat patients with liver and kidney diseases, erosive-ulcerative ulcers and a history of gastrointestinal bleeding, with increased bleeding or with simultaneous anti-inflammatory therapy. Acetylsalicylic acid, which is part of the drug, even in small doses reduces excretion uric acid from the body, which can cause acute attack gout in patients with sensitivity to it. It is not recommended to use Citramon-F for more than 5 days as an analgesic and 3 days as an antipyretic without consulting a doctor. If kidney and liver function are impaired, the interval between doses should be at least 8 hours. During treatment with the drug, you must avoid drinking alcohol. With long-term use necessary control the blood coagulation system and the level of hemoglobin.

There is no experience using the drug in children.

The drug does not affect the ability to drive vehicles and work with complex mechanisms.

Interaction with other drugs. The drug enhances the effect of other non-steroidal anti-inflammatory drugs, indirect anticoagulants, . Combines well with acetylsalicylic acid, ibuprofen,. The effects are potentiated when combined with codeine, ascorbic acid, chlorphenamine, propyphenazone.

When used simultaneously with antacids that contain magnesium or aluminum salts, the absorption of acetylsalicylic acid slows down and worsens. Simultaneous use with glucocorticoids increases the risk of erosive and ulcerative damage to the gastrointestinal tract.

The drug weakens the effect of diuretics, antihypertensives, and anti-gout drugs that promote the excretion of uric acid. Increases the concentration of digoxin, barbiturates and lithium salts in the blood plasma.

Simultaneous use of Citramon-F with tricyclic antidepressants, barbiturates, anticonvulsants, alcohol significantly increases the risk of hepatotoxic complications.

Storage conditions and periods. Store at a temperature between 15 °C and 25 °C, in a dry, protected

away from light and out of the reach of children. Shelf life - 2 years.

How often do you take citramon? Does it really happen sometimes? When the weather changes, when you drank too much yesterday, or when you get a headache from stress before an important meeting. How often have you come across instructions for using citramon? Probably never in my life. Because citramon is not sold in boxes and one instruction is included with a dozen blisters. So, if you did not study to become a pharmacist or doctor, then you are unlikely to have come across this annotation. But citramon has a number of contraindications and side effects. Therefore, if you take citramon from time to time, read this article to the end.

First, let’s talk about how citramon works in the body. All components of citramon: acetylsalicylic acid, paracetamol, caffeine and vitamin C act together, enhancing each other’s effect. Once in the body, citramon is ninety percent absorbed by the body. Within half an hour after administration, the drug begins to act. Paracetamol blocks the central nervous system...

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Pharmacological action of "Citramon"

pharmachologic effect"Citramona" is determined by the influence of each active substance included in its composition. Acetylsalicylic acid has an antipyretic and anti-inflammatory effect, relieves pain symptom caused by inflammation, improves blood circulation in the area inflammatory process. Caffeine has an stimulating effect on the central nervous system and psychomotor centers; it expands blood vessels, reduces the feeling of fatigue, drowsiness, has a slight analgesic effect, stimulates physical and mental activity. Paracetamol has antipyretic, analgesic and moderate anti-inflammatory effects.

"Citramon" relieves pain syndromes of moderate severity. It helps with headaches, toothaches, muscle pain, joint pain, neuralgia, feverish conditions and painful menstruation. The drug should be taken one tablet three times a day.

In some...

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Citramon for hangover

Symptoms of a hangover are a severe headache, aches throughout the body, and sometimes you can even notice an increased temperature. Citramon is known as a pain reliever. Especially popular for headaches, toothaches, and menstruation. Can he help in this case? How long does the tablet last? When should it be taken, before or after meals? In order to understand this, you need to understand what components are included in this drug. It contains caffeine, so it is most often recommended for people with low blood pressure. But wine raises blood pressure. How will taking this medicine affect a person’s hangover? In the pharmacy there are several types of the drug called Citramon. How do they differ, when and how much can they be taken?

Composition of the drug Citramon

In addition to the traditional Citramon for headaches and toothaches, you can find in pharmacies: Citramon P, Aquacitramon, Citramon forte.

What is the difference...

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Citramon tablets are known to many as effective remedy for headaches. Their shelf life is 5 years.

Mechanism of action. Citramon is a complex medicine consisting of aspirin (acetylsalicylic acid), phenacetin, caffeine, cocoa and citric acid. That's why overall effect citramone on the body is the sum of the effects of the individual drugs it contains. Thus, aspirin has an anti-inflammatory effect (see aspirin), phenacetin improves mood and enhances the anti-inflammatory activity of aspirin (in particular, its analgesic, antipyretic, decongestant effect), caffeine improves blood supply to the brain, mental and physical performance, memory and mood of a person, cocoa contains caffeine and another substance similar to it, therefore it also has a stimulating and tonic effect on the body, and lemon acid(citrate) is an energy substrate necessary for brain cells. Thus, citramon is...

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Citramon is one of the analgesics “for all occasions”. Many ordinary people believe that if you get sick somewhere or have a fever, you need to take a pill and everything will go away. One of these " magic pills“Citramone is also considered.

Citramon, like other analgesics such as analgin, pentalgin, spasmalgon, are most often used for headaches to stop an attack. It quickly stops pain and reduces dizziness if it was caused by low blood pressure and poor circulation, since active ingredients make the blood more fluid and improve the functioning of blood vessels. In addition, the drug not only relieves pain from inflammation, but also helps reduce it.

Some patients are also prescribed it for migraines and neuralgia, severe toothache before and after visiting the dentist, diseases of the blood vessels and muscles of the head, which cause discomfort. It is also indicated for pain, including headaches, before and during menstruation in women.

Most often citramon...

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Citramon

One of the most common medications for headaches is Citramon. Surely, each of us has a name this drug will be familiar, because its effectiveness and low cost have contributed to the fact that it has become an integral part of the home medicine cabinet in almost every family.

Citramon is a combination drug that has antipyretic, anti-inflammatory and analgesic effects. It contains three main components: paracetamol, caffeine and aspirin, which act separately. Caffeine, for example, helps improve the functioning of blood vessels; it gives a person additional strength, allowing him to forget about fatigue. The action of aspirin is aimed at lowering body temperature, reducing inflammation and pain. This substance has a positive effect on blood supply in the area of the inflammatory process. Paracetamol also helps reduce body temperature, relieving pain.

There are several forms in which this product is produced...

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What are Citramon tablets for: instructions for use, composition, contraindications

Surely many people in home medicine cabinet there is Citramon. This drug is the development of Soviet pharmacologists. If, while abroad, a person asks for Citramon, they simply will not understand him. After all, this medicine is registered only in post-Soviet countries. What does Citramon tablets help with and how to take it correctly?

Contents: Composition of citramon Indications for use Side effects Contraindications

Composition of Citramon

Citramon is produced by many domestic pharmaceutical companies. This combination drug from NSAID groups, which consists of several medicinal components at once. The original composition of Citramon included the substance phenacetin, but due to its high toxicity it was no longer added to the drug. Classic Citramon consists of three components:

Paracetamol at a concentration of 180 mg; Acetylsalicylic acid - 240 mg; Caffeine - 30 mg....

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Citramon P - why is it so effective?

Citramon contains three active ingredients - aspirin, paracetamol and caffeine. Aspirin belongs to the group of non-steroidal anti-inflammatory drugs. It works by blocking the activity of one of the body's chemical compounds, cyclooxygenase.

Cyclooxygenase is involved in the production of various chemical substances in the body, among which are prostaglandins. The production of prostaglandins begins in response to injury and some diseases and causes associated discomfort.

Aspirin is used to relieve pain and inflammation. Paracetamol is a medicine used to relieve mild to moderate pain. In addition, it has a weak antipyretic effect. Caffeine is a mild stimulant that is often included in various painkillers in small doses. Caffeine is believed to enhance the pain-relieving effects of aspirin and paracetamol.

The combination of these analgesics...

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Citramon - what do we know about it?

Tell me when last time When you went to the pharmacy and bought citramon, did you take instructions for it along with your purchase? Once upon a time a long time ago? When did you read it? How much did you understand from this?

Did you know that Citromon CANNOT be taken:

Pregnant

Nursing

Children under 15 years old

For gastritis or ulcers

With severe arterial hypertension (high blood pressure)

After drinking alcohol

For insomnia (sleep disorders)

For glaucoma

With caution in case of liver diseases

Impressive, huh?
What do you think of the popular thoughts about citramone: if your head hurts, take citramone - it will help anyone - and if it doesn’t help, it won’t hurt; menstruation makes it difficult to live with pain - citramon, citramon is the safest medicine, take citramon for a cold and so on, yesterday I had a good rest - it will help again, drink often...

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Instructions for use, contraindications and reviews

Inexpensive but fast-acting Citramon is familiar to almost every woman. Not everyone uses it Everyday life, but many people know that Citramon helps with various pains, elevated temperature and inflammatory processes. Most often, it is women who resort to its help, because it can improve the condition during menstrual bleeding, although it has a blood-thinning effect (that is, it can potentially cause bleeding), which not everyone thinks about.

And yet, the main difference between Citramon, for which people “loved” it, is its pronounced analgesic effect. This drug is quite quickly and almost always able to eliminate or reduce headaches, toothaches, and muscle pain, thanks to which it has received a reliable registration in our home medicine cabinets.

Fenpiverinium bromide (an antispasmodic), reducing the hypertonicity of smooth muscles, blocks painful sensations and has a relaxing effect.

...

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Citramon is an over-the-counter drug. This means that the patient can take it on his own, but in this case he must clearly know the mechanism of action of this drug and its side effects, since possible complications Such treatment will depend on the patient himself.

Mechanism of action of citramon

Citramon (more correctly citramon P, since citramon, which contained phenacetin, is no longer available, it was replaced by paracetamol) is a combination drug that has an analgesic, mild antipyretic and mild anti-inflammatory effect. All these properties are due to the drugs included in citramon.

Aspirin (acetylsalicylic acid) is the first medicinal product, belonging to the group of non-steroidal anti-inflammatory drugs (NSAIDs), it is very well studied and both its positive and negative properties. To the positive properties...

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One of the most popular and sought-after drugs remains the drug “Citramon”.

What is the drug

The drug "Citramon" (the instructions for it must be read before use) is a combined, hormone-free analgesic that has anti-inflammatory, antipyretic and analgesic effects.

Active Ingredients

This medicine is manufactured by a fairly large number of companies, so its composition may differ slightly from one company to another. All varieties relieve inflammation, have a positive effect on capillary permeability, reduce temperature, thin the blood, and relieve pain. The caffeine they contain increases blood pressure, improves the functioning of the heart and nervous system, dilates blood vessels, positively affecting their tone, reduces fatigue, and gives activity to the mind and body. The drug also includes cocoa, which is a natural antidepressant and has a stimulating...

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pharmachologic effect

A combined drug, the effect of which is determined by the effects of its constituent components. Acetylsalicylic acid has antipyretic, anti-inflammatory and analgesic effects due to inhibition of prostaglandin synthesis. Phenacetin has antipyretic and analgesic effects. Caffeine affects the tone of blood vessels in the brain, and also enhances the effect of acetylsalicylic acid and phenacetin in this combination.

Indications

Moderate pain syndrome of various etiologies: headache, migraine, toothache, neuralgia, arthralgia, myalgia, algodismenorrhea;
febrile conditions due to acute respiratory viral infections, influenza and rheumatic diseases

Dosage regimen

The drug is taken orally.
Prescribed to adults and children over 14 years of age, 1-3 tablets. 3 times/day. The maximum daily dose for adults is 6 tablets.

Side effect

Possible: heartburn, nausea, epigastric pain,...

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In almost every home you can find this drug, which “rescues” fever, inflammation in the body, and also has an analgesic effect. Moreover, all the components that make up this medication are absolutely safe. It's about about Citramon.

Pharmacokinetics

The residue of citramon contains 3 of the most active active ingredients, which are aimed at providing the following effects:

Analgesic; Antipyretic; Anti-inflammatory.

Citramon contains: acetylsalicylic acid, paracetamol and caffeine. Now let's look at the action of each component separately. So, acetylsalicylic acid has an antiperitic effect. This substance affects the central nervous system and the hypothalamus (part of the brain). If we turn to medical and more scientific terms, acetylsalicylic acid suppresses the growth of the inflammatory process, having a direct effect on...

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Citramon is an analgesic and antipyretic drug, characterized by its availability and low cost. This is a popular and best-selling headache medication. Therefore, it is important to know in what dosage it is recommended to take Citramon, whether it can cause intoxication and how to act in case of overdose.

Features of the drug

Citramon consists of 3 main components:

paracetamol in a dosage of 0.18 g.
acetylsalicylic acid in a dosage of 0.24 g.
caffeine in a dosage of 0.03 g.

This drug is used in the following cases:

headache or toothache;
low blood pressure;
pain in the muscles;
fever.

You should know that Citramon should not be taken with drinks containing caffeine. This can lead to a sharp rise in blood pressure, since the drug also contains a certain amount of this component.

An overdose of Citramon can occur only in cases where the recommended dosage of the drug is significantly exceeded. The cause may be either inattention or accidental intake of a large amount of medication, or a suicide attempt. Fortunately, cases of Citramon poisoning are quite rare.

To avoid intoxication, it is important to know following features dosage and administration of the drug:

Citramon is taken 1-1.5 hours after meals;
a one-time therapeutic dosage corresponds to 0.5 - 1 g. (1-2 tablets) for persons over 18 years of age;
the average daily norm is 4-5 tablets;
the maximum duration of treatment to reduce temperature should not exceed 3 days, and to eliminate pain syndromes– 5 days;
the interval between taking tablets should be at least 2 hours.

When does an overdose occur?

An overdose of Citramon can occur with a single use of more than 7-8 tablets. In addition, poisoning can also be chronic form, if a person regularly takes the drug in a higher dosage. In such cases, signs of intoxication will appear gradually, increasing after each pill intake.

In some categories of people, symptoms of overdose may occur even if the recommended dosage of the drug is observed. The risk group includes people suffering from liver or kidney diseases. The process of metabolism and removal of drug residues from the body is disrupted. Because of this, the components of Citramon can accumulate in it, causing an overdose.

It is also worth noting that drinking the tablets with caffeine-containing drinks can provoke intoxication with Citramon.

Be poisoned by this analgesic before fatal outcome almost impossible.

Symptoms

The severity of overdose symptoms depends on the number of tablets eaten. Moreover, the first signs of intoxication appear only 2-3 days after administration. large quantity drug. This is due to the fact that the caffeine contained in Citramon compensates for hypertension, keeping blood pressure within acceptable limits. And after 2-3 days this substance is removed from the body and ceases to act.

The development of overdose symptoms is due to the influence of its main components. Let us consider separately what effect each of them has on the body when a person exceeds therapeutic dose drug.

Significant excess caffeine provokes the following symptoms:

An excess of acetylsalicylic acid or paracetamol causes symptoms such as:

In severe overdose, when the therapeutic dosage of Citramon is significantly exceeded, the following symptoms may additionally appear:

convulsions;
breathing problems (choking);
bleeding (internal and external);
disturbance of consciousness.

First aid

Citramon intoxication requires work emergency care. It is necessary to minimize as much as possible the time during which the drug remains in the gastric cavity.

First aid should be provided in the following sequence:

Cleanse the stomach. An “artificial” gastric lavage procedure is performed. To do this, you need to give the victim 1.5-2 liters of clean liquid to drink. It is preferable to use filtered water at room temperature. Then gently press on the root of the tongue, inducing vomiting. The procedure can be repeated if necessary. It can be considered effective if vomit The (fluid) coming out of the stomach will become clear.
Accept sorbent. This product is necessary for cleaning digestive tract from accumulated toxic components. Sorbents absorb harmful substances, neutralize and quickly bring them out. The most effective are: Smecta, Enterosgel, Polysorb, Polyphepan.
Observe drinking regime . For any form of poisoning, it is important to drink a lot. The body needs a lot of fluid. The following drinks will be useful: filtered water, Regidron, mineral water(non-carbonated), dried fruit decoction.

Features of inpatient treatment

There is no specific antidote to Citramon! Therefore, therapy carried out in a specialized clinic includes procedures that restore acid-base balance and removing toxins from the body.

Treatment is carried out according to the following scheme:

Appointed infusion therapy. Special solutions are injected dropwise into the patient to restore the water-salt balance.
Intestinal lavage is performed. 8-10 liters are injected into the stomach cavity saline solution For rapid elimination toxins.
Hemodialysis is performed (a method of extrarenal blood purification).
An antidote to paracetamol, acetylcysteine, is administered.
Antipsychotics are prescribed. These drugs are intended to treat psychotic disorders, also have calming properties. Aminazine is most often used.
Antihypertensive drugs are used to level out caffeine residues. The most effective include Enap and Clonidine.

Possible consequences

The consequences of an overdose of Citramon can pose a serious threat to human health, especially in cases where the victim was unable to provide first aid in time.

The most common consequences of Citramon intoxication are:

liver dysfunction. The components of the drug have a toxic effect on the liver, leading to the death of its cells - hepatocytes. It will take a long time for the organ to recover;
stroke. People with severe hypertension are at risk. In most cases, headaches are caused by increased blood pressure. Many people prefer to quickly get rid of it with the help of Citramon, but they only make the situation worse. In such cases, caffeine can provoke cerebral vascular spasms. In a person with heart disease, this causes hemorrhagic or ischemic stroke.

Citramon – reliable assistant in the fight against pain! But it is important to take it correctly and as directed. Only if you follow the instructions and dosage can you be sure of the effectiveness of the drug. Otherwise, treatment may result in an overdose.

Citramon is an analgesic and antipyretic drug that contains caffeine and paracetamol. Distributed through pharmacies, available without a prescription, today it is one of the most popular drugs used for headache problems. It is practically not used as an antipyretic. An overdose of Citramon is quite rare in toxicological practice.

Rules for using Citramon

Normally, Citramon is used in the following cases:

Contraindications to the use of Citramon are:

hypertonic disease;
pregnancy;
bleeding;
pathology of the blood coagulation system;
increased mental excitability;
liver failure.

Ignoring these contraindications does not lead to the appearance of overdose symptoms, but provokes an exacerbation of the underlying disease and significantly worsens the patient’s condition.

The drug does not have a pronounced analgesic effect, therefore it can only be used for pain syndrome of moderate and weak degree gravity. When treating, you should also remember how Citramon acts on patients suffering from hypertension. The medicine contains a large amount of caffeine. Accordingly, it can provoke a sharp rise in pressure and the development of a hypertensive crisis.

The therapeutic dosage of Citramon is 4-5 tablets per day for an adult. In this case, it is recommended to take the drug in stages, 1 tablet every 2 hours. IN severe cases It is allowed to take 8 tablets per day. More high doses lead to an overdose, the symptoms of which will be described below.

Actually, an overdose of Citramon can only occur when attempting illiterate self-medication. As a rule, this remedy is not used for the purpose of suicide. It is also possible to take too much of the drug by mistake when the patient confuses the drug with other tablets. A similar mechanism of poisoning occurs mainly in elderly people.

Overdose symptoms

Symptoms of overdose depend on the amount of the drug eaten and are caused by two active ingredients. Caffeine, distinguished by its ability to influence blood pressure and the nervous system, gives the following symptoms:

tachycardia;
heart rhythm disturbances;
vasodilation (appears only when taking high doses);
dyspnea;
respiratory arrest;
convulsions;
headache;
mental arousal (in the most severe cases, caffeine can have a depressing effect on the psyche).

When paracetamol, which affects most internal organs and systems, begins to be absorbed, the patient experiences signs of poisoning such as:

In general, an overdose of Citramon can have various clinical manifestations. The interaction between paracetamol and caffeine plays a role here - if, when poisoned with pure paracetamol, the patient almost immediately experiences severe hypotension (BP 80/40 and below), then the toxic effect of Citramon leads to the development of hypotension only 2-3 days after consuming the tablets. Before this, caffeine, which is part of medicine, compensates for hypotension, allowing pressure to remain within acceptable limits. Afterwards, the caffeine is eliminated and stops working. It may take 6-10 days for paracetamol to clear from the body.

First aid

An overdose of Citramon requires assistance emergency assistance. In this case, the time that the tablets remain in the stomach should be minimized.

The algorithm for providing treatment benefits does not differ from that for any other drug poisoning. Before the emergency medical team arrives, you must:

rinse the stomach using the “restaurant” method - to remove the drug, you should give the patient a drink clean water(up to 1-1.5 liters), then induce vomiting. Repeat the procedure several times. The taken tablets will be washed away with water;

Give activated carbon at the rate of 1 tablet per 10 kg of patient weight. Activated carbon is able to deposit a certain amount of tablets on himself and remove them through the intestines. In the absence of coal and other sorbents, the victim should be given milk to drink;

Call EMS

Symptoms of Citramon poisoning do not allow you to treat an overdose on your own - full treatment can only be started in a specialized hospital.

Even with mild degree poisoning, the patient is hospitalized, since such intoxications often have delayed consequences - death from paracetamol poisoning most often occurs 3-5 days after taking the drug. In turn, even slight increase Caffeine-induced blood pressure can trigger the development of myocardial infarction in people with existing coronary disease hearts.

Treatment of poisoning

There is debate about how long it takes for paracetamol to be eliminated in a hospital. However, there is no doubt that active infusion therapy significantly reduces the time required for detoxification.

The patient can be given up to 10 liters of fluid per day, after which strong loop diuretics are prescribed - a toxicant dissolved in the blood is well excreted by the kidneys.

The second treatment method is intestinal lavage. When using this innovative method in combination with other treatment methods, the symptoms of poisoning disappear within 24 hours. The essence of the method is to introduce 8-10 liters of saline solution into the patient’s stomach, which leads to the development of profuse diarrhea and the elimination of the toxicant along with the stool.

The most complex and expensive method of detoxification is hemodialysis. In this case, the patient’s blood is forced through a special purifying filter that is capable of passing elements of the internal environment, but retaining particles of chemical substances unusual for the body.

Antidote therapy consists of administering Acetylcysteine to the patient, which is an antidote to paracetamol. The effect of caffeine can usually be neutralized by prescribing antipsychotics (aminazine) and antihypertensive drugs (Enap, Clonidine). Similarly, assistance is provided in cases where there is not an overdose, but side effects Paracetamol or Citramon (nausea, vomiting, heartburn, headache, tinnitus).

Overdose Prevention

To the question of whether Citramon is harmful and why this drug is dangerous, the answer can only be unequivocal - harmful and dangerous if used incorrectly.

Proper use of the drug, taking into account contraindications and possible side effects, allows you to avoid negative effects. To avoid overdose and associated symptoms, you should follow a few simple rules:

do not exceed the single and daily dose indicated in the annotation;
use the medicine strictly according to indications;
Avoid taking Citramon if there are contraindications;
hide medicine from children;
monitor medication intake by people with mental disorders;
monitor medication intake in older people.

If there are signs of Citramon poisoning ( characteristic symptoms, tablet blisters near the patient, unconsciousness after attempts at self-treatment).

Citramon is a popular medication that perfectly relieves headache, menstrual pain, and also used in therapy viral diseases. It relieves hangover symptoms well.

Pharmacological properties

Citramon belongs to the anti-inflammatory drugs from the analgesic group. Produced in tablet form. It has both contraindications and advantages, which are determined by its composition.

Compound

This analgesic is a combination non-hormonal agent, which includes three main components:

acetylsalicylic acid ( tradename aspirin) in the amount of 0.24 g;
caffeine in the amount of 0.03 g;
paracetamol in the amount of 0.18 g.

Aspirin

This component affects inflammation processes, relieving the pain they cause.

It can improve blood circulation by reducing platelet aggregation. This ensures sufficient blood supply to the site of inflammation.

Aspirin is able to quickly act and be absorbed without residue, being converted in the intestinal cavity into intermediate metabolic products (metabolites).

Caffeine

It has the ability to dilate blood vessels, enhances excitatory activity spinal cord, eliminates spasmodic phenomena and a feeling of drowsiness.

The share of its quantitative composition in acetylsalicylic acid small, because it helps to increase blood flow, while it does not affect the activity of the central nervous system. Caffeine is absorbed by the intestines and excreted unchanged in an amount of 10%, bypassing the metabolic process.

Paracetamol

This substance has analgesic and antipyretic properties. This effect occurs by influencing the thermoregulatory center of the hypothalamus. Absorbed upper sections intestines and is excreted from the body through the kidneys.

Complex impact

Thanks to this composition, citramon is effective for both mild and moderate pain in cases of inflammation. Its effect on the body is manifested in:

Flaws

In contrast to the benefits, citramon also has side effects. Among them:

from the outside immune system: anaphylaxis, rhinitis, bronchospasm;
from the outside skin: itching, rash, urticaria, Stevens-Johnson syndrome, angioedema and etc.;
from the gastrointestinal tract: vomiting, heartburn, gastrointestinal hemorrhage, exacerbation chronic diseases Gastrointestinal tract;
hepatobiliary disorders: increased active work liver enzymes(without jaundice), hepatonecrosis;
endocrine disorders: hypoglycemia, hypoglycemic coma is not excluded;
from the central nervous system: dizziness, tremor of the limbs, paresthesia, fear, excitability, insomnia, tinnitus;
from the cardiovascular system: tachycardia, high pressure, arrhythmia;
from the outside circulatory system: thrombocytopenia, bleeding, anemia.

And no less important is information about taking other medications at the moment.

take the drug after 1-2 hours;
wash down simple warm water(it is prohibited to use drinks containing caffeine as a drink);
a single dose corresponds to 0.5-1 g for adults;
the average dose per day corresponds to 4 tablets;
The maximum duration of treatment is 5-7 days.

In addition, if there is no individual medical prescription, then the maximum duration of the course when the temperature decreases is 3 days, when the pain syndrome is eliminated - 5 days.

Elderly patients or those with kidney and liver dysfunction should reduce the dosage and increase the interval between doses.

Non-compliance

Despite the effectiveness medication, they can be poisoned. In particular, an overdose of citramone is possible when you take 7-8 tablets at a time. Cases fatal outcome medical practice not known.

Possibility of overdose

Symptoms of overuse of medication can occur not only due to non-compliance with recommended standards, but also in people suffering from certain diseases.

People with kidney or liver disease are at risk. IN similar cases the metabolic process is disrupted, and the process of removing the drug from the body becomes more complicated.

It accumulates in it, causing symptoms of overdose.

Signs of intoxication

Intoxication can be provoked by the fact that the medication was washed down with a drink containing one of its components. Basically, symptoms indicating poisoning with citramone are caused by the influence of each of the components that make up its composition.

The important question is how long it will take for signs of toxemia to appear. If an overdose of pure paracetamol is immediately manifested by obvious hypotension, then the toxic effect of citramone leads to its development only 2-3 days after taking the drug. Until this point, caffeine compensates for the development of hypotension, helping to maintain normal blood pressure. Afterwards it is removed and has no effect. In contrast, paracetamol is eliminated from the body after 6-10 days.

Excess aspirin and paracetamol

Symptoms caused by excess of these components are characterized by:

gag reflexes and subsequent vomiting;
pain in the epigastric zone of a pulling nature;
internal and external bleeding;
exacerbation of chronic diseases.

Excessive dose of caffeine

A significant excess of this component causes:

IN severe form an overdose of citramone will manifest itself in convulsions, nosebleeds and internal organs, deterioration in breathing and loss of consciousness.

Chronic form

Many people, with the desire to quickly get rid of pain syndromes of various types, systematically violate the recommended norms when taking medication. In case of prolonged abuse, disturbances in the functioning of many organs develop, leading to negative consequences:

peptic ulcer of the gastrointestinal tract;
renal failure;
liver failure;
disruption of the blood clotting process, which leads to hemorrhages and anemia;
a decrease in the level of glucose in the bloodstream, glycemic coma is likely;
malfunction of the cardiovascular system, arrhythmia, increased blood pressure, rapid pulse.

Emergency care and treatment

An overdose of this drug requires emergency treatment. Moreover, the time during which the medicine remains in the stomach must be minimized.

First aid

Residues of the drug are removed using standard methods. The algorithm of actions before the arrival of the emergency team is as follows:

gastric lavage in the “restaurant” way - by taking 1-1.5 liters of water and inducing vomiting;
taking sorbent drugs (if they are absent, you can drink milk).

Profile help

What drug can neutralize the effects of this drug? There is no specific antidote to citramon. That's why health care in a specialized clinic consists of procedures that restore the acid-base balance and remove toxins from the body:

infusion therapy;
intestinal lavage - injection of 8-10 liters of saline solution into the stomach cavity (thanks to it, the symptoms disappear within a day);
hemodialysis;
introduction of an antidote to paracetamol - acetylcysteine;
taking antipsychotics;
reception antihypertensive drugs to level out caffeine.

Similar treatment is carried out during side effects.