home Audience 4 But spa intramuscularly instructions for use. No-shpa - what helps

But spa intramuscularly instructions for use. No-shpa - what helps

No-spa is a drug for relieving spasms.

pharmachologic effect

No-spa dilates blood vessels, reduces muscle tone internal organs, reduces intestinal peristalsis, while the drug does not affect the central nervous system.

The active substance of the drug is drotaverine hydrochloride, which is similar in action to papaverine, but is characterized by a more pronounced, long-lasting effect.

When administered intravenously therapeutic effect occurs in 2-4 minutes.

Release form

No-spa tablets and solution are produced.

Indications for use No-shpa

The drug is effective for spastic constipation and spastic colitis, pyelitis, tenesmus, proctitis, gastroduodenitis, gastrointestinal ulcers, endarteritis, spasms of the coronary, cerebral and peripheral arteries, algodismenorrhea.

In addition, No-shpa is prescribed according to the instructions for the treatment and prevention of muscle spasms of internal organs due to kidney, intestinal, biliary colic, cholecystitis, dyskinesia of the gallbladder, bile ducts, postcholecystectomy syndrome.

No-shpa is used during pregnancy to relieve the threat of miscarriage, prevent premature birth . In obstetric practice, the drug is used to relieve spasm of the uterine pharynx during childbirth, in case of prolonged opening of the pharynx, and to relieve postpartum contractions.

The drug is also used for cholecystography and instrumental examinations.

Instructions for use No-shpa

Orally No-shpu according to the instructions is prescribed in a dosage of 120-240 mg ( daily dose), which is taken two or three times a day. The maximum permissible single dosage of No-shpa tablets is 80 mg, and the daily dosage is 240 mg.

The drug is administered intramuscularly to adults in a volume of 40-240 mg/day for 1-3 administrations. For acute biliary and renal colic the drug is administered intravenously at a dosage of 40-80 mg over 30 seconds.

No-shpu for children 6-12 years of age is prescribed at a dosage of 80 mg in two doses, for children over 12 years of age - 160 mg in 2-4 doses.

The permissible single dosage when prescribing No-shpa to children 6-12 liters is 20 mg, daily dosage is 200 mg.

When using the product independently, without a doctor’s prescription, it should be taken into account that therapy should last no more than one or two days. If after this period the pain has not been relieved, you should seek medical advice. medical assistance
to clarify or clarify the diagnosis.

No-shpu during pregnancy is prescribed to take an average of 3-6 tablets/day when characteristic symptoms increased tone uterus - stretching and pain in the lower abdomen. Good effect gives a combination of the drug with papaverine and valerian. It is recommended to take No-shpa during pregnancy only as prescribed by a doctor, strictly following the instructions.

Side effects

The product may cause palpitations, fever, increased sweating, dizziness, low blood pressure, allergies.

Because of intravenous use No-shpa, the patient may experience collapse, arrhythmia, and respiratory depression. To prevent the development of these conditions, a patient with low blood pressure should be in a supine position during the infusion procedure.

Due to an overdose of No-shpa, the excitability of the heart muscle may decrease, paralysis of the respiratory center, and cardiac arrest may occur.

Contraindications to the use of No-shpa

According to the instructions, the drug No-shpa is contraindicated in case of severe heart disease, liver failure, hypersensitivity to the drug, intolerance to sodium disulfite (with intramuscular, intravenous administration).

No-shpa tablets should not be taken if you have galactose-glucose malabsorption syndrome, congenital galactose intolerance, or lactase deficiency.

Intramuscular and intravenous administration The drug is contraindicated for children under 18 years of age, and the tablet form of No-shpa is contraindicated for children under 6 years of age.

For patients with gastrointestinal ulcers, No-Spa is usually prescribed simultaneously with antiulcer drugs.

Since dizziness often begins after intramuscular or intravenous administration of the drug, it is recommended to refrain from driving vehicles or operating other complex, potentially dangerous mechanisms for another hour after the procedure.

During therapy, it should be taken into account that the drug can weaken the effect of Levodopa, the antispasmodic effect of Morphine, and enhance the effect of Bendazole, Papaverine, and other antispasmodics. Phenobarbital increases the antispasmodic activity of the drug.

Sincerely,

"No-spa" is a drug that has an antispasmodic and vasodilator effect. With the help of this medicine You can reduce the tone of smooth muscles and muscles of internal organs. In its action, it is superior to its analogues. At the same time, this strong effect this drug does not become negative factor for the functioning of the central and autonomic nervous system.

When taking this medicine, its active substance, drotaverine, acts only on the muscles of the internal organs. Therefore, this antispasmodic is used in the treatment of patients for whom anticholinergic drugs are contraindicated.

The effect of taking this medicine occurs within a few minutes. After half an hour the phase begins maximum effect from taking this antispasmodic.

No-shpa release form

Each form contains active substance– drotaverine, as well as some additional compounds: talc, lactose, corn starch, etc.

Pills

The tablet form of “No-shpa” is presented in the form of orange or yellow-green biconvex pills with the letters “spa” on one of their sides. One tablet contains 40 mg of drotaverine hydrochloride
Tablets are indicated for muscle spasms in diseases such as: cholecystitis, cholecystolithiasis, cholangitis, papillitis, cystitis, cystitis, uro- and nephrolithiasis, pyelitis and tenesmus Bladder
Also, No-shpa tablets are used to relieve spasms in diseases of the stomach and intestines, as an anesthetic for headaches caused by spasms blood vessels

Solution

The use of this drug in ampoules is indicated if taking tablets, according to various reasons impossible

The No-shpa solution does not contain lactose. Therefore, it can be used to relieve spasms in patients with intolerance to this carbohydrate.
Injections with this drug are prescribed to patients with impaired glucose absorption syndrome, galactosemia and lactose deficiency.
For pancreatitis complicated by strong gag reflexes, you can also use only injections of this drug

No-spa indications for use

The instructions for this drug indicate that it is necessary to use “No-shpa” in case of antispasmodic pain caused by:

Urolithiasis
Peptic ulcer of the stomach and duodenum
Chronic cholecystitis
Postoperative spasms
Disorders of the duct of blood vessels in the head

No-spa dosage

This drug must be used in strictly prescribed dosages.

For adults, 120–240 mg of this drug per day is indicated. It must be taken 2-3 times. You can take no more than 80 mg of this antispasmodic at a time
Daily intake rate intravenous solution"No-spa" is 40-240 mg. Single dosage 40-80 mg. It is possible to use three injections of this drug per day with 2-3 hours between them
It is possible to take No-shpa on your own for no more than two days in a row. If the drug does not give desired effect you must seek help from a qualified specialist

No-shpa for children

This medicine is contraindicated for children under one year of age. Although many mothers ignore this instruction and give “No-shpu” infants for intestinal colic
As a rule, no negative consequences Taking this drug does not cause this. In minimal quantities, the active substance of this antispasmodic, when mixed with mother's milk, has a “mild” effect. But, before taking this method, it is better to consult a doctor.
Children from 1 year to 6 years old can use “No-shpa” in the amount of 40 – 200 mg of the drug in 2-3 doses. Your doctor will tell you the exact dosage

Children over 6 years old can use this remedy in the amount of 80-200 mg in 2-5 doses.

IMPORTANT: No-shpa should not be given to a child who is lactose intolerant and allergic to drotaverine.

No-spa side effects

The most severe negative reactions when taking this antispasmodic were recorded when it was administered by injection.

No-spa contraindications

This antispasmodic should not be taken if you have glaucoma or hypersensitivity to its components.

No-spa overdose

When taking this antispasmodic over permissible norm it is necessary to induce vomiting and rinse the stomach
At the same time, there is an urgent need to ensure clinical control the affected person and provide symptomatic and supportive therapy

No-spa during pregnancy

Carrying a child is a very important stage in the life of every woman.

And the main task is right choice medications to treat problems that arise during this period. They must be effective and not harm the unborn child.
Experts have proven that taking No-shpa during pregnancy cannot harm the baby and recommend using this remedy to relieve increased uterine tone
Therefore, all women carrying a child should always have this drug on hand.

No-shpa or Papaverine

Both drugs are classified as antispasmodics with myotropic action. They can reduce muscle tone and dilate blood vessels. This relieves muscle spasms
In terms of severity of action and effectiveness, “No-shpa” is several times superior to “Papaverine”. It is also important to know that Papaverine is poorly soluble in aqueous media.
Therefore, it is more effective to take it intravenously or rectally. As for the No-shpa tablets, taking them is not complicated by this. They can be taken at any time. As a rule, these tablets are always on hand

Analogs

"Drotaverine hydrochloride". Tablets with antispasmodic and vasodilating effects. They are used in the treatment of cholecystitis, pyelitis, stomach ulcers and spasms caused by other diseases.

Dosage – 1-2 tablets 2-3 times per day

"Drotaverine Forte". Antispasmodic myotropic action. Available in tablet form. In terms of components and structure it is close to Papaverine, but surpasses it in action and effectiveness.

Dosage – 1-2 tablets 1-3 times a day

"Spazmol". Myotrobic antispasmodic based on drotaverine hydrochloride. Therefore, it has the same scope and effectiveness.

"Spazmonet". Myotrobic antispasmodic based on drotaverine hydrochloride. Used for spasms of smooth muscles.

Dosage – 1-2 tablets 2-3 times a day

Catherine. Always at acute pain I use No-shpu. It works within 10-15 minutes. But somehow this medicine was not in the medicine cabinet. I went to my neighbor and he said that he uses drotaverine instead of No-shpa. She gave it to me. Personally it didn't work on me. I only recommend “No-shpu” to everyone.

Sonya. The child got sick. I lay in bed with him, and I saw his hands became cold. I called my pediatrician. She said to urgently give “No-shpu”. Half a tablet. That's what I did. After 20 minutes, the hands became warm again. I’m even afraid to think about what would have happened if it weren’t for the doctor’s advice and No-Spa in the medicine cabinet.

Video: ALL ABOUT PILLS [Pain of various origins]

How to use No-shpu intramuscularly? Let's find out in this article.

The drug "No-shpa" is a drug based on the substance drotaverine, which is produced in the form of tablets and ampoules. The medicine has an antispasmodic effect and is used in the treatment of spastic syndrome digestive tract, reproductive, hepatobiliary and urinary systems. In addition, this medication relieves spasms cerebral vessels for headaches resulting from overexertion as a result of depression and neuroses, and peripheral vessels with Raynaud's disease or endarteritis.

The active substance is a derivative of papaverine. Generic international name medicines "No-shpa" - "Drotaverine". According to the clinical and pharmacological classification, it is classified as a myotropic antispasmodic. In its properties, the substance is very similar to papaverine, but has a longer and more pronounced relaxing effect on muscle fibers.

The effectiveness of a pharmacological agent is due to its ability to exert an inhibitory effect on the enzyme phosphodiesterase, which, through a series of chemical reactions is able to catalyze the inactivation of myosin chain kinase. This kinase phosphorylates myosin and provokes muscle contraction. When it is relieved, muscle relaxation is maintained. Positive properties The drug also consists of selective suppression of only the fourth type of PDE, which does not affect the third type enzyme and does not cause negative side effects from the blood vessels and heart.

Drotaverine causes muscle relaxation when spasms of both neurogenic and myogenic nature occur and, regardless of the type of innervation, relaxation muscle fibers. A significant advantage of this medication is that there is no stimulating effect on the cholinergic system, as a result of which the drug “No-shpa” can be used in people suffering from a disease such as glaucoma. However, some caution must be exercised when taking it, especially in the presence of prostatic hypertrophy, since symptoms of urinary retention may occur due to relaxation of the detrusor muscle in the bladder. So No-Spa is prescribed intramuscularly very often.

Composition and release form

Medical product"No-shpa" for intramuscular injection produced in glass ampoules containing 2 ml of injection solution. The volume of the active element in 1 ml is 20 mg of drotaverine. Injections can be carried out through intra-arterial, intravenous and intramuscular administration. The solution has a bright yellow-green color.

Indications for use

Indications for the use of the pharmacological agent "No-shpa" intramuscularly are the prevention and treatment of organ functional disorders And pain syndrome caused by:

muscle spasms digestive organs tract with ulcers, gastritis, dyskinesia, pancreatitis, spastic enteritis, proctitis or colitis, as well as in the event of spasms of the pylorus or cardia, irritable bowel, development of flatulence, spastic constipation, tenesmus;
disruption of the functionality of the hepatobiliary system due to inflammatory processes in the gallbladder or its ducts, hyperkinetic forms of biliary dyskinesia, cholelithiasis;
excessive excitability of the uterus during pregnancy;
spasms of the urinary system with the development of kidney stones, pyelitis, urolithiasis, neurogenic bladder, pyelonephritis, cystitis;
spasms of the uterine pharynx during the birth process;
prolonged opening of the uterine pharynx;
postpartum contractions;
threat spontaneous miscarriage;
menstruation.

This is stated in the instructions. “No-spa” is also used intramuscularly when spasms of cerebral and peripheral vessels occur. Effective for postoperative colic due to gas retention, preparation for exercise instrumental studies, postcholecystectomy syndrome.

Use of “No-shpa” injections for children

Children under six years of age are prohibited from injecting the drug intramuscularly. It is important to know that the main substance of the drug is synthesized artificially. In other words, it is not a natural element. Therefore, No-shpu is usually used intramuscularly for children only as prescribed by a specialist.

The medicine is a good antispasmodic, but does not have an analgesic effect like, for example, Analgin and it similar drugs. In addition, it has some contraindications for use, which should also be taken into account when treating children.

Instructions for use for No-shpa injections indicate that usually this medicine prescribed to young patients following cases:

which is accompanied high temperature and coldness of the extremities.
Spasms due to bronchitis or stenosis, causing coughing.
Spasms that provoke headache.
Renal or intestinal colic.
Excessive painful gas.
Smooth muscle spasm during pyelitis or cystitis.
Spasms due to gastritis or colitis.

Contraindications for the use of No-shpa injections for children are:

age up to 6 years;
low blood pressure in a child;
intolerance to drotaverine;
vascular diseases;
bronchial asthma;
suspicion of presence intestinal obstruction;
suspicion of acute appendicitis;
liver and kidney failure.

In accordance with the instructions for use, No-shpy injections can be administered during pregnancy.

Use during pregnancy

Among the medications that are widely used during pregnancy, No-spa plays a special role. Being a powerful antispasmodic, this medicine eliminates any painful sensations associated with temporary dysfunction of the digestive tract in expectant mothers. In addition, during pregnancy this medication is absolutely safe and can be used without any fear.

However, even taking into account these properties of the drug, caution should be exercised when using it in this period, since it has certain indications for use, contraindications and negative side reactions.

During pregnancy, No-Spa can be prescribed intramuscularly for hypertonicity of the uterus and the threat of premature birth. At the first symptoms of premature birth or threat of spontaneous miscarriage, such as pulling painful sensations in the lower abdomen and a feeling of fullness in this area, a single use of No-shpa in most cases completely eliminates uterine hypertonicity and helps maintain pregnancy.

Another indication for the use of this pharmacological drug is spasm of the smooth muscles of the uterus and cervix during childbirth. This situation is dangerous because the child is in a clamped state - excessive tension in the myometrial muscles helps expel it from the uterus, but the contracted cervix prevents its movement through the birth canal. In most cases, one dropper with this medicinal solution enough to restore normal birth process. The intramuscular dosage of No-shpa must be strictly observed.

Contraindications

The main contraindication to the use of this drug, like many other drugs, is the manifestation of severe disorders of the liver, kidneys, and heart, caused by insufficiency of their functions.
In addition, the drug “No-shpa” is not prescribed during breastfeeding, since drotaverine and other representatives of this pharmacological category can penetrate into mother's milk.
The use of the drug is allowed from 6 years of age, but only in tablet form, since studies of the effects injection solutions were not carried out, according to which the use medical product Parenteral administration is contraindicated.
Taking the medication is contraindicated if you have a high sensitivity to the active element or other substances from its composition.
This medicine can only be used if certain precautions are taken in case of low blood pressure due to high probability development of collapse, as well as during pregnancy.

What is the dosage of No-shpa intramuscularly?

Dosage regimen and methods of administration

A single dosage of the drug “No-shpa” in the form of solutions for intramuscular, intraarterial and intravenous administration, depending on medical indications, is 1-2 ampoules. The frequency of such injections is 1-3 times a day. How to administer No-shpu intramuscularly is indicated in the instructions.

At labor activity or after an abortion, administration of the drug in an amount of 80 mg is allowed with a time interval of at least 2 hours. How long does it take for No-shpa to work? Intramuscular and intravenous injection allows you to get desired result after 5 minutes. That's why injections of this medication got wide use.

Side effects

Negative side reactions that may occur when using this pharmacological drug develop extremely rarely. Most often, its effect negatively affects the nervous system, gastrointestinal tract, blood vessels and heart.

Nervous system: cephalalgia, dizziness, sleep disturbance.
Circulatory system: increased or rapid heartbeat, feeling of heat, irregular heartbeat, decreased blood pressure(sometimes to the point of collapse), atrioventricular blockade.
Digestive system: dyspepsia, nausea, stool disorders.

In addition to the above negative actions of this medication there is some information about such side effects, such as breathing problems, excessive sweating, allergic reactions. Local redness or burning sensation may occur. Most often this manifests itself when the dosage of No-shpa injections is not observed.

There are also special instructions that should be strictly followed when using the No-Spa medication:

Compliance required increased measures caution when treating patients who suffer from atherosclerosis coronary arteries or low blood pressure.
The medicine is approved for use in complex therapy hypertensive crisis.
A question about management vehicle when using the drug it is decided in individually, especially when it occurs negative impact. In this case, it is advisable to refrain from driving and activities associated with the use of complex mechanisms, when using an antispasmodic in injection forms. If dizziness occurs after administration of No-shpa, it is prohibited to perform these types of work intramuscularly.
According to clinical research, this medical product does not have embryotoxic or teratogenic effects. However, it is necessary to remember possible risk in relation to the fetus and use the medication only according to strict medical indications with precautions. The use of medication during pregnancy in the form of injections is undesirable.
The use of an antispasmodic during labor can cause the development of postpartum atonic bleeding.
IN pharmacological agent metabisulfite (sodium disulfite) is contained as an auxiliary element, which must be taken into account if hypersensitivity to him.
When administering this medication parenterally, patients suffering from hypotension should take horizontal position body due to the high probability of collapse.

What else does the instructions for “No-shpe” (intramuscular) tell us?

Drug interactions

Drotaverine, like other papaverine derivatives that inhibit PDE enzymes, can reduce the antiparkinsonian properties of levodopa, as well as increase muscle rigidity and tremor. With simultaneous therapy with other antispasmodic medications, mutual potentiation of antispasmodic effects may be observed. This pharmacological drug in injection form enhances the decrease in blood pressure caused by the use of antidepressants, quinidine or procainamide. This is confirmed by the instructions for use of No-shpa injections intramuscularly.

This medication reduces the spasmogenic effectiveness of morphine. When using phenobarbital, the antispasmodic effect of the drug “No-shpa” increases. Taking into account high level binding to plasma proteins (more than 80%) does not exclude the possibility of competition of this drug with medications that have the same feature. Taking this fact into account, if a combination of such drugs is used, the toxic effect of the medications taken may be enhanced.

Analogs

The medical product "No-spa" in the form of injection solutions has many analogues that have the same composition, but different bioequivalence and bioavailability. These medications include:

“Nosh-bra” is a medicine from the category of myotropic antispasmodics. By pharmacological properties And chemical structure close to papaverine, but has a longer and stronger effect. Reduces the level of calcium ions entering smooth muscle cells (suppresses phosphodiesterase, promotes the accumulation of intracellular cAMP). Reduces muscle tone of organs and peristalsis, dilates blood vessels. It has no effect on the autonomic nervous system and does not penetrate the central nervous system. The presence of a direct effect on smooth muscles allows the use of this drug as an antispasmodic in situations where medications of the M-anticholinergic class are contraindicated (prostatic hyperplasia, angle-closure glaucoma).
"Spazmol" is a medicine that is an antispasmodic with myotropic effects. Distinctive feature of this pharmacological drug is the presence of a long-lasting effect. The medicine affects not only the smooth muscles of internal organs, but also the walls of blood vessels. It can be taken to prevent the development of spasms or their presence in colitis, cholelithiasis, to eliminate spasms of the gastrointestinal tract, brain, to reduce the tone of the uterus, dilate blood vessels, and reduce peristalsis in the intestines.
“Spakovin” is an antispasmodic with myotropic effectiveness, similar in properties to papaverine, but superior to it in effectiveness and duration of action. Reduces the tone of internal organs, their motor activity and has a vasodilating effect.

Other analogues of the drug “No-shpa” are:

Price

The cost of this medication in the form of ampoules No. 5 ranges from 70 to 190 rubles per package, in the form of ampoules No. 25 - up to 320 rubles. It depends on the region and pharmacy chain.

To relieve a sudden spasm, eliminate pain, the hands themselves reach for the first aid kit. There lies No-shpa - faithful assistant for all family members at any time of the day. This antispasmodic will quickly relax smooth muscles and help relieve spasms of the heart and blood vessels. For some people, the pain remedy has been lying around for months, waiting in the wings. But as soon as the spasm makes itself felt, the little yellow tablets quickly neutralize it.

Instructions for use of the drug No-shpa

When buying tablets without a doctor’s prescription, you need to carefully study the instructions and make sure that there are no serious restrictions on taking the drug. The instructions indicate the composition of the tablets, in what cases they can be used, and to whom they are strictly contraindicated. It says what No-shpa helps with, and what dosage is needed for various pains at different ages.

You should pay attention to the possibility of taking the medicine for expectant mothers and women who are breastfeeding. The instructions were compiled by specialists, it takes into account everything possible reactions for other drugs if they are taken simultaneously with No-shpa. special instructions there are concerns about alcohol and driving a vehicle.

Indications for use, or what No-spa helps with

Doctors prescribe an antispasmodic different profiles. Urologists and gynecologists, surgeons and therapists, cardiologists and gastroenterologists.

There are basic indications for starting to use this drug:

Colic of the liver and kidneys;
Gastrointestinal diseases;
Various pain sensations in the muscles;
Stomach spasms due to ulcers;
Severe headaches and painful periods;
Relieving spasms during the removal of bile stones.

No-spa is used by gynecologists during pregnancy. early stages to exclude the possibility of miscarriage. Obstetricians also use the drug to open the uterus during childbirth.

Dosage, or how to use No-shpu correctly

Indications for use of No-shpa must be followed by dosage. Depending on how old the person is and the spasm of which organ needs to be eliminated, the number of tablets that can be taken during the day is prescribed.

Read also: Instructions for use of the drug.

Directions for use for children

If the child is under 6 years old, he is prescribed half a tablet in the morning, at lunch and at dinner. From 6 to 12 years it can already be 1 or 2 tablets with each meal. When giving the drug to children, you should definitely consult a doctor to exclude all contraindications.

Directions for use for adults

Children over 12 years of age and adults take 2 tablets 3 times a day. The dose may be reduced or increased as directed by the doctor or depending on the intensity of the cramps.

The tablet should be swallowed without chewing, with a sufficient amount of water. It is recommended to take No-shpa during or immediately after meals so that the drug is quickly absorbed into the body.

Intravenous administration

No-spa in ampoules is prescribed by a doctor in cases where sudden attacks and colic when passing stones. It is administered intravenously. The dosage is set only in medical institution. Emergency workers can also administer the drug in solution to quickly relieve pain. An insertion into a vein is made experienced specialist only in a lying position, avoiding overdose.

Composition, description and pharmacotherapeutic group

No-spa has a simple composition: 40 mg of drotaverine, starch, povidone, lactose, magnesium and talc. This drug can be immediately distinguished from others by yellow color, convex round shape and three letter markings – “spa”. No-spa in ampoules and tablets belongs to the group of antispasmodics.

Pharmacokinetics of the drug

As soon as drotaverine enters the stomach with water or food, it is completely absorbed by the intestines. The drug is quickly and evenly distributed throughout all types of tissues and muscles, and penetrates the cells. Relaxation of spasms and pain relief occurs within 20 minutes after taking the tablets, and 5-10 minutes after injection into a vein. The action stops after 6-8 hours. It is completely eliminated from the body within three days.

Contraindications to the use of tablets and side effects

The indications for the use of No-shpa indicate when this drug is prescribed by a doctor and when it can be taken independently. But there are a number of diseases for which the use of tablets and injections is strictly prohibited or should be done with great caution after consulting a doctor.

Moderate to severe renal and liver failure;
Low blood pressure, hypotension;
Sensitivity to the components of the drug;
Atherosclerosis, serious eye diseases;
When feeding babies with breast milk;
Pregnancy, except necessary appointments doctor;
Serious heart disease.

There are cases of allergy to drotaverine. As soon as a rash appears on the body, itching and slight redness of the skin on the hands begins, taking No-shpa for headaches, coughs, severe cramps should be stopped immediately. Treatment can be resumed only if the allergy is not confirmed.

Sometimes patients complain about various reactions body after you start taking No-shpu by prescription or on your own. These may be signs of arrhythmia or a slight decrease in blood pressure. It happens that you start to feel dizzy or feel hot throughout your body. Rare complaints of sweating and drowsiness.

No-shpa: analogues and prices in Russia

No-spa has analogues in the same way as other basic drugs. Analogs are those that contain the original active substance and have the same effect on the body when taken.

The most effective and popular analogues of No-shpa:

and Nosh-bra;
Dolce and No-h-sha;
Noxhaverine and two more forms of Drotaverine: forte and hydrochloride.

You should not prescribe an analogue to yourself. Only a qualified doctor can determine which drug to replace the original if necessary. Both Drotaverine and No-shpa have absolutely the same effect on the body of a child and an adult. The only difference is the manufacturer and the possibility of counterfeiting.

Drotaverine is not counterfeited because it is much cheaper than No-shpa. When purchasing a drug at a higher cost, you should ask the pharmacist for a certificate, and also take out one tablet to check the labeling. The price of Drotaverine ranges from 50 to 90 rubles. No-shpu in tablets can be purchased from 100 to 250 rubles, in injections - up to 450 rubles.

No-shpa for children: when can you give it?

Starting from 12 months, the drug can be prescribed to children with the following diseases and symptoms:

Headache that does not stop within an hour;
High temperature and muscle spasms due to its increase;
Pain due to cystitis and kidney stones;
Intestinal problems, constipation.

Sometimes parents give No-shpa for cough or bronchitis to ease expectoration. But doctors cannot say for sure whether the drug has required action in this case.

No-shpa is drug, reducing the tone and contractile dynamics of smooth muscle tissue of the gastrointestinal tract, urogenital, vascular systems, urinary, gall bladders; relieves spasm and pain.

Instructions for use of the drug No-shpa include information about the cost, rules for using the drug in tablet, injection form, comparative characteristics with an analogue that has an identical active ingredient.

Composition and release form

The drug No-shpa is manufactured in the form of tablets and a dissolved substance for injection use.

Photo

In addition to instructions for use, the packaging of No-shpa contains:

The tablets are yellow in color, convex in shape, with the word “spa” engraved on one side; there are 6.24 tablets in the blister plate.
Plastic bottles equipped with a dispenser, containing 60, 100 tablets.
Solution for injection, produced in ampoules of two ml., There are 5.25 pieces in a pack.

The active ingredient of No-shpa is drotaverine hydrochloride, the content of which in the tablet is 0.04 g.

Additional components of No-shpa:

enterosorbent – povidone;
a compound of magnesium salt and octadecanoic acid;
lactose monohydrate;
silicate mineral – talc;
corn starch.

No-shpa solution for parenteral use contains an active component similar to the above form, additional components according to the instructions are: sodium metabisulfate; ethanol; liquid d/i.

One of the main causes of constipation and diarrhea is use of various medications. To improve bowel function after taking medications, you need to do it every day. drink a simple remedy ...

Mechanism of action

Myotropic antispasmodic No-shpa is prescribed for diseases of the digestive system, has an effect on smooth muscle tissue this part of the body, the biliary tract, as well as the genitourinary and vascular systems.

The active component of tablets and injections is . It has an antispasmodic effect on smooth muscle tissue by inhibiting the PDE 4 enzyme, which causes an increase in the concentration of cyclic AMP and, due to the inactivation of MLCK, leading to complete relaxation of smooth muscles.

No-spa has effects on spasmodic contractions of smooth muscle tissue of both neurotropic and myotropic nature; dilates blood vessels, which affects increased blood circulation in tissues.

The advantages of using No-shpa instead of papaverine are:

In the most intense and prolonged antispasmodic activity;
In the most rapid and extreme absorption of the substance;
In the absence of such an undesirable reaction as stimulation of breathing when the drug is administered intramuscularly or intravenously.

The active substance No-shpa is rapidly absorbed and reaches its maximum concentration approximately an hour after administration. The metabolic process takes place in the liver, complete elimination from the body occurs in three days, more than half is excreted in the urine, about thirty percent with feces.

Indications for use

What does No-shpa help with?

Instructions for use of the drug No-shpa highlight the following pathological conditions for prescription:

Indications for taking No-shpa for therapeutic purposes.
Spasmodic contraction of smooth muscles in pathologies gallbladder and biliary tract: cholecystolithiasis, papillitis, inflammation of the gallbladder and its outer shell, bile ducts.
Spasmodic contractions in pathologies urinary system: nephrolithiasis, ureteral stones, inflammation renal pelvis, bladder and painful urges to urination.

Indications for taking No-shpa as a promoting agent:

Spasmodic contractions of smooth muscles during pathological conditions organs of the gastrointestinal tract: esophagospasm, ulcer of the stomach and duodenum, with constipation caused by spastic colitis, accompanied excessive gas formation, pylorospasm, inflammatory process stomach, small and large intestine.
For characteristic pain in the lower abdomen during menstrual bleeding.
Tension headache.

Features of use

Lactose, which is part of No-shpa, can provoke gastrointestinal complaints in patients with intolerance to the component of the same name.

The instructions warn about undesirable use of No-shpa to persons suffering from the following diseases:

galactosemia;
hypolactasia;
lactase deficiency;
syndrome of poor absorption of glucose-galactose.

Side effects

According to the instructions, taking the drug No-shpa is rarely accompanied by the occurrence of undesirable responses of the body.

Among isolated cases of occurrence adverse reactions noted:

Immunity: itchy rash, fever, angioedema, redness skin, chills, hyperthermia, loss of strength.
Gastrointestinal tract: isolated cases of constipation, nausea, vomiting.
CNS: dizziness, sleep disturbance, pain in the head.
Circulatory system: decreased blood pressure, tachycardia.

Overdose

The use of the drug No-shpa in significantly higher doses threatens the patient with arrhythmia and impaired cardiac conduction, which provokes the occurrence of complete blockade element of the conduction system and cardiac arrest.

Instructions for use of No-shpa informs that a patient with an overdose is under medical supervision, performing symptomatic therapy, including procedures with gastric lavage and induction of vomiting.

Contraindications

The drug No-shpa is not allowed for use:

Children under six years of age;
Nursing mothers;
Patients with excessive sensitivity to the active and auxiliary components of the drug.
Patients suffering from severe liver, kidney, or heart failure;

Under the supervision of a doctor, No-shpa tablets should be used when carrying a child, especially in the first trimester of pregnancy.

How long does it take to work?

When hitting intestinal tract No-spa begins to act quickly, which makes it a highly active antispasmodic agent. The analgesic effect of No-shpa in tablets occurs through quarter of an hour - half an hour, in injections later five minutes after application.

Mode of application

The course of treatment and indications for use of No-shpa are established by a specialist individually for any category of persons. The instructions for No-shpe do not contain data on the dependence of the drug on food intake (before or after meals), from which we can conclude that it can be taken at any time.

Self-administration of No-shpa tablets should not exceed three days.

Pills

Dosage for children from 6 to 12 years. The maximum daily dose is 0.08 g of drotaverine, divided into several doses (one No-shpa tablet twice a day).

Teenagers. The maximum permissible dose per day is 0.16 g, divided into 2-4 doses (one tablet 2-4 times a day).

Adults. On average, taking No-shpa daily is 0.12 - 0.24 g for two or three doses (you are allowed to drink no more than six tablets in 24 hours).

No-spa in injections

For children, the use of No-shpa in this form is excluded.

For adults, the daily dose ranges from 0.04 – 0.24 g. for one to three intramuscular injections.

At acute colic in patients with gallstones, urinary tract, No-shpa injection is given intravenously in a dosage of 0.04-0.08 g.

Drotaverine and No-shpa: what is the difference?

Having studied the instructions for both medications, it becomes obvious that they are actually similar in almost all respects. The table shows Comparative characteristics Drotaverina with No-shpa.

Drotaverine
General properties
Concentration active substance in both drugs it is identical – 40 mg. Myotropic data antispasmodics have a relaxing effect on the contractile muscle tissue of the gastrointestinal tract, urinary, biliary, urogenital, and vascular systems, relieving pain and spasms. Release form of both Drotaverine and No-shpa - ampoules for parenteral administration and tablets for oral administration. Method of administration side effects, contraindications for use are the same.
Differences
Manufacturer
Russia	Hungary
Price
From 6 to 30 UAH. /12 to 50 rub.	From 50 to 350 UAH. / from 50 to 500 rub.
Childhood
Up to three years	Child under six years old
Application in gynecology
If there is a threat of premature termination of pregnancy, to weaken the tone of the uterus, relieving cervical spasms during and after the birth process.	Dysmenorrhea
What is better No-shpa or Drotaverine?
An obvious distinctive property of the drugs No-shpa and Drotaverine, which is noticeably striking, is the price. Why is it so big and is it worth overpaying for No-shpu? The fact is that No-shpa is patented medicinal product. The presence of a patent indicates the quality of the medicine and imposes responsibility on the manufacturer for its safety and mandatory clinical trials. Drotaverine is a generic drug sold under the INN, which has a low cost due to the lack of ongoing clinical trials, development costs.

Analogs

The following analogues of No-shpa are similar in pharmacological properties, mechanism of action and active ingredient:

Spakovin;
Dolce;
Biospa;
Bespa;
Nokhshaverin.

Photos of analogues:

Price

The cost of the drug No-shpa is approximate, the price may vary depending on trade margin specific pharmaceutical point of sale. To obtain factual information about the availability and price of a medicine, it is advisable to contact the nearest pharmacy in the desired city.

Release form	Kyiv	Kharkiv	Moscow	Novosibirsk
Pills: No-shpa No. 6	There is no data on the sale of No-shpa in this dosage.		52.5	57
No-shpa No. 24	50.25	49.2	120	119
No-shpa No. 60	141.4	118.7	207	205
No-shpa No. 100	208.6	180.2	230	230
Injections: No-shpa No. 5	There is no data on sales in Ukraine.		98	97
No-shpa No. 25	317, 20	260.2	490	480
	UAH		Rub.

additional information

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Trade name: No-shpa (written in Latin No-spa), international name(INN) – Drotaverine.

Manufacturer: Chemical and Pharmaceutical Enterprise - Chinoin, Budapest, Hungary. Holder of a trade license in Russia and Ukraine - pharmaceutical company Sanofi. Sanofi is also represented in Ukraine medications like No-shpa Forte, No-shpalgin.

According to the instructions for use, the expiration date is different for each dosage form of No-shpa:

Ampoules with injection solution and No-shpa tablets in blister vinyl packaging - three years at temperatures below 25 degrees Celsius.
No-spa in tablets in a plastic bottle - five years from the date of manufacture, when stored in a dark place, at a temperature not exceeding 25 degrees Celsius.
No-shpa tablets in aluminum blister packaging – five years at air temperatures up to 30 degrees Celsius.

The medicine should be stored in a place safe from access by children and protected from moisture. Pharmacies do not require a prescription to purchase the drug No-shpa. Before taking No-shpa, you should obtain a specialist’s recommendation and carefully study the instructions for use.