What are Kagocel tablets for? Influence on the ability to drive vehicles and machinery. The composition of Kagocel includes
Kagocel – synthetic drug, belonging to the group of immunostimulants and antiviral agents for systemic use.
Release form and composition
The medicine is produced in the form of biconvex tablets containing 12 mg of the active substance of the same name.
Excipients used in the production of Kagocel are calcium stearate, potato starch and ludipress (in other words, direct pressing lactose) containing lactose monohydrate, crospovidone and povidone (kollidon 30).
Pharmacological properties of Kagocel
Kagocel is a drug created on the basis of new developments and pharmacological nanotechnologies due to the fact that microbiologists and epidemiologists managed to combine the molecule medicinal substance(and more importantly - plant origin) with a nanopolymer. This synthesis significantly increased the effectiveness of the drug.
According to the instructions, Kagocel has a complex effect on the human body: antiviral, immunostimulating, antimicrobial and radioprotective.
The main mechanism of action of the drug is its ability to induce and enhance the production of interferon (a natural protein secreted by the body in response to viral invasion) in almost all cells involved in the antiviral response: endothelial cells, macrophages, fibroblasts, granulocytes, T- and B-lymphocytes . In this case, the drug promotes the formation of so-called late interferon, which is a mixture of α- and β-interferons that have the highest antiviral activity.
Pharmacokinetics
When taken orally as a single dose (which is usually 2 tablets) maximum concentration In the blood serum, the interferon titer reaches after 48 hours, but in the intestines its peak value is observed after 4 hours.
As for the body’s interferon response, it is characterized by a fairly long (up to 5 days) circulation of the protein in the bloodstream.
When using Kagocel in therapeutic doses it has no toxic effects, does not accumulate in the body, and does not have teratogenic, mutagenic or embryotoxic properties.
The greatest effectiveness of Kagocel, according to reviews, is achieved when taking the drug no later than the fourth day after the onset of symptoms acute infection.
In order to prevent a viral disease, the medication can be used at any time, optimally - as soon as possible after direct contact with a sick person.
Kagocel's analogs
By active substance structural analogues Kagocel is not produced.
By belonging to one pharmacological group analogues of the drug are: Altabor, Amizon, Amizonchik, Arbidol, Armenicum, Arpeflu, Groprinosin, Isoprinosine, Imustat, Novirin, Panavir, Flavozid, Erebra and others.
Indications for use
As indicated in the instructions for Kagocel, the drug is intended for:
- Prevention and treatment of influenza and acute respiratory infections viral infections in adults and children over 6 years of age;
- Treatment of influenza and SARS in children older than 3 years;
- For the treatment of herpes virus in adults;
- For the treatment of urogenital chlamydia in adults (as part of complex therapy).
Contraindications to the use of Kagocel
Even if there are indications, Kagocel is not prescribed:
- In case of increased individual sensitivity to the active or any of the auxiliary components of the drug;
- Pregnant and breastfeeding women;
- Children under 3 years old;
- With diagnosed lactase deficiency, lactose intolerance or glucose-galactose malabsorption syndrome.
Directions for use and dosage
If the indication for Kagocel is viral infections or influenza, the following regimen is recommended for adults for medicinal purposes: course - 4 days, total number of tablets - 18, which are taken as follows: the first two days, 2 tablets. (loading dose) three times a day, the next two days, 1 tab. also three times a day.
For the purpose of prevention viral diseases and influenza in adults, the drug is taken in 7-day cycles: the first two days, 2 tablets at a time, once a day, then a five-day break, after which the described scheme is repeated. The duration of the preventive course of Kagocel can be one week or several months.
For the treatment of children 3-6 years old, the following scheme is provided: course - 4 days, total number of tablets - 6 pieces, which should be taken as follows: the first two days, 1 tablet twice a day, then for another two days, 1 tablet. once a day.
When treating children over 6 years old, the following scheme is used: the course of treatment is 4 days, the total number of tablets is 10, which should be taken as follows: the first two days, 1 tablet. three times a day (loading dose), after which the next two days take 1 tablet. morning and evening (the interval between doses is 12 hours).
In order to prevent viral diseases and influenza in children over 6 years of age, Kagocel, according to the instructions, is taken in 7-day cycles: the first two days, 1 tablet once a day, then a five-day break, then the described scheme is repeated. The duration of such a course is at least 1 week, but can last for several months.
For the treatment of herpes virus and complex therapy of urogenital chlamydia, adults are prescribed to take 2 tablets three times a day for 5 days.
Side effects of Kagocel
As they say in reviews of Kagocel, the drug is well tolerated in more than 95% of cases. Extremely rare cases Allergic reactions occur due to intolerance to individual components.
Additional Information
When using Kagocel, it should be borne in mind that when it is simultaneous reception with antibiotics, immunomodulators and others antiviral agents an additive effect is observed (i.e., enhancing each other’s action).
The medicine is dispensed from pharmacies without a doctor's prescription. Its shelf life is 24 months.
zdorovi.net
Kagocel - instructions, application, reviews
Kagocel is an antiviral, immunostimulating drug.
Active substance
Kagocel.
Release form and composition
Kagocel is sold in the form of tablets. Medical drug is produced in blister packs (10 tablets each), placed in carton boxes 1 pc.
Indications
Indications for prescribing a medication are: herpes therapy in adult patients, treatment and prevention of influenza and other acute respiratory viral infections in children (in particular, aged 3 years and over) and adults.
Contraindications
Contraindications to the use of Kagocel are:
- Lactose intolerance, acute lactase deficiency, glucose-galactose malabsorption.
- Hypersensitivity to the main and auxiliary components of Kagocel.
- Children under 3 years of age.
- The period of gestation and breastfeeding.
Directions for use and dosage
Kagocel is intended for oral use. When treating ARVI and influenza, the recommended dosage regimen for adult patients in the first 2 days is 2 tablets. with a frequency of 3 times a day, and the next 2 days - 1 tablet. 3 times a day. The duration of the therapeutic course is 4 days (a total of 18 tablets per course).
Prevention of ARVI and influenza is carried out in 7-day cycles. The patient is prescribed 2 tablets for 2 days. 1 time per day, then take a 5-day break. Then the cycle is repeated again. The prophylactic course should last from 1 week to several months.
For the treatment of herpes Kagocel, take 2 tablets. 3 times a day for 5 days. The duration of the course of treatment with the drug is 5 days (a total of 30 tablets per course).
For the treatment of acute respiratory viral infections and influenza, the drug is prescribed to children according to the following scheme:
- At the age of 3 to 6 years - in the first 2 days, 1 tablet. with a frequency of 2 times a day, in the next 2 days, 1 tablet. with a frequency of 1 time per day. The duration of the treatment course is 4 days (a total of 6 tablets per course).
- From 6 years and older - in the first 2 days, 1 tablet. 3 times a day, in the next 2 days, 1 tablet. with a frequency of 2 times a day. The duration of treatment is 4 days (10 tablets each).
For the prevention of acute respiratory viral infections and influenza, children aged 3 years and older are given a 7-day cycle: 2 days - 1 tablet. Once a day, then a 5-day break is taken and the cycle is repeated again. The duration of use of tablets is from 1 week to several months.
Side effects
When using Kagocel, it is possible that allergic manifestations. The patient should inform the specialist about any changes in his health.
special instructions
To achieve the best therapeutic effect The drug should be taken no later than 4 days from the onset of the disease.
At sharing Kagocel with other antibiotics, immunomodulators and antiviral drugs an additive effect is observed (the total effect of all drugs).
The effect of the drug on the ability to work with complex mechanisms and car control vehicles not studied.
Storage conditions and periods
Store at a temperature not exceeding 25 °C. Keep away from children. Shelf life – 2 years.
Attention!
The description of the drug posted on this page is a simplified version of the official version of the annotation for the drug. The information is provided for informational purposes only and does not constitute a guide for self-medication. Before using the drug, you should consult with a specialist and read the instructions approved by the manufacturer.
dolgojit.net
Kagocel
The main mechanism of action of the drug is its ability to induce the production of interferon. Kagocel causes the formation in the human body of the so-called late interferon, which is a mixture of α-, β- and γ-interferons with high antiviral activity. Kagocel produces interferon in almost all cell populations involved in the body's antiviral response: T- and B-lymphocytes, macrophages, granulocytes, fibroblasts, endothelial cells. When one dose of the drug is taken orally, the titer of interferon in the blood serum reaches its maximum values after 48 hours. The dynamics of interferon accumulation in the intestine when taking the drug orally does not coincide with the dynamics of circulating interferon titers. In the blood serum, the production of interferon reaches high values only 48 hours after taking Kagocel, while in the intestine the maximum production of interferon is noted already after 4 hours.
Kagocel, when used in therapeutic doses, is a non-toxic drug that does not accumulate in the body. The drug has no mutagenic, teratogenic and carcinogenic properties, has no embryotoxic effect.
Maximum effectiveness in treatment with Kagocel is achieved when it is used no later than the 4th day from the beginning. acute period infections. For prophylactic purposes, the drug can be used at any time, including immediately after contact with an infectious agent.
24 hours after administration to the body, Kagocel accumulates mainly in the liver, to a lesser extent in the lungs, thymus, spleen, kidneys, and lymph nodes. Low concentrations of the drug are observed in adipose tissue, heart, muscles, testes, brain tissue, and blood plasma. The low content of Kagocel in the brain may be due to the large molecular weight of the drug, which makes it difficult to penetrate the BBB. In plasma, the drug is found predominantly in bound state.
With daily repeated administration Kagocel's volume of distribution fluctuates widely in all studied organs. The accumulation of the drug is especially pronounced in the spleen and lymph nodes. At oral administration about 20% of the administered dose enters the general circulation. After entering the bloodstream, the drug circulates in the blood, mainly in the form associated with macromolecules: with lipids - 47%, with proteins - 37%. The unbound portion of the drug is about 16%.
Excretion of the drug from the body occurs mainly through the intestines: 7 days after administration, 88% of the administered dose is excreted from the body, including 90% with feces and 10% with urine. In exhaled air, the drug is not determined.
Indications
Kagocel is used in adults as a prophylactic and therapeutic agent for influenza and other respiratory viral infections, herpes, as well as for urogenital chlamydia.
Kagocel is used in children over the age of 6 as a remedy for influenza and other respiratory viral infections.
Application
For treatment of influenza and acute respiratory viral infections, adults are prescribed 2 tablets 3 times a day in the first 2 days, 1 tablet 3 times a day for the next 2 days. Total duration course of treatment - 4 days, during which the patient takes 18 tablets.
For the treatment of herpes in adult patients, take 2 tablets 3 times a day for 5 days. Total for the course - 30 tablets, course duration - 5 days.
For treatment of urogenital chlamydia in adults, take 2 tablets 3 times a day for 5 days.
Prevention of respiratory viral infections in adults is carried out in 7-day cycles: 2 days - 2 tablets once a day, the next 5 days do not take the drug (break), then the cycle is repeated. The duration of the prophylactic course is from 1 week to several months.
For the treatment of influenza and other respiratory viral infections in children over 6 years of age, it is prescribed in the first 2 days - 1 tablet 3 times a day, in the next 2 days - 1 tablet 2 times a day. The total duration of the course of treatment is 4 days, during which the patient takes 10 tablets.
Contraindications
Increased individual sensitivity to the components of the drug; During pregnancy and breastfeeding.
Side effects
Perhaps the development of allergic reactions.
special instructions
In order to achieve therapeutic effect Taking Kagocel should begin no later than the 4th day from the onset of the first symptoms of the disease.
Interactions
The drug combines well with other antiviral drugs, immunomodulators, antibiotics and antibacterial drugs(note the additive effect).
Overdose
In case of accidental overdose, nausea and pain in the epigastric region are noted. It is recommended to appoint drinking plenty of fluids, induce vomiting.
Storage conditions
At room temperature (15 to 25 °C).
it-apharm.ru
How to take Kagocel for adults and children
Kagocel is effective medicinal product, which is effective against viral diseases. Before purchasing it, you need to find out about its indications and methods of use. It would be useful to familiarize yourself with inexpensive analogues Kagotsela.
Kagocel is known for its strong therapeutic effect on harmful microorganisms. It helps make the immune system stronger. The medicine stimulates the production of interferon in the body.
You need to know how to take Kagocel, as this will help speed up the process of restoration of areas damaged by infection.
The drug is also an excellent prophylactic agent.
Properties of Kagocel and application
This inexpensive, effective antiviral drug has a simple chemical composition which helps to quickly absorb useful components. The drug contains the active substance kagocel, which is a synthetic compound. Emulsifiers, stearates, food colors and starch are used as additional ingredients.
Often, for viral pathologies, the doctor prescribes Kagocel. The price of the medicine varies between 200-300 rubles.
At Kagotsel the following readings:
- Different types flu
- Active forms herpes.
- ARVI.
- Infectious chlamydia.
- Prevention of colds and viral infections.
- Various viral infections.
By using of this medicine the immune system is restored, the body’s defenses increase, the process of eliminating infection is accelerated, and the removal of free radicals that cause tumor formation.
The use of Kagocel for adults
Special attention requires Kagocel's instructions. To get rid of ARVI and different forms Influenza adults are shown three times a day, two tablets. So you should take the medicine for two days, and the next few days - one tablet at a time. The duration of the whole course is 4 days.
The approaching season of viral infections causes anxiety among many mothers who want to protect their son or daughter from flu and colds. That is why in the autumn-winter period there is an increased demand for antiviral drugs, which include Kagocel.
How does such a drug affect the child’s body and does it cause harm? Is it allowed to give it to small children, for example, under one year old? Is this medication used for prophylactic purposes and what medications can it be replaced if necessary?
Release form
Kagocel has been produced by the domestic company Nearmedic Plus since 2003 only in tablet form. Syrups, capsules, powders, ampoules and other forms of the drug are not produced.
There is also no separate pediatric form of the medication. Kagocel tablets have one dosage for all ages, and depending on the purpose of use and the age of the patient, only the dosage regimen, the number of tablets per dose and the duration of use of the drug change.
The characteristics of the tablets are white-brown color, round shape, and the presence of brown inclusions. One pack may contain 10, 20 or 30 such tablets. Children most often buy the smallest package, since it is enough for one course of treatment and for several weeks of prophylactic use.
Compound
The active ingredient of the drug is called kagocel, which determined the name of the tablets. This synthetic compound is obtained by merging plant molecules with nanopolymer molecules and is represented by a dosage of 12 mg in one tablet. In addition, the compounds in the medicine are calcium stearate, potato starch, crospovidone, lactose monohydrate and povidone. All these additional substances They are considered harmless, but in some children they provoke allergies, so it is important for mothers of children with allergies to know the composition of any medications.
Now let’s listen to the pediatrician about the drug Kagocel.
Operating principle
The medication is classified as an antiviral agent, since Kagocel has the property of activating the production of alpha and beta interferons. These substances have quite strong antiviral activity, so they are synthesized in the human body during the immune response to virus attack. The drug stimulates almost all cells immune system– B lymphocytes, macrophages, granulocytes, T cells and others.
Taking Kagocel has the following effects:
- Strengthens the body's defenses;
- Restores immunity;
- Accelerates the death of infectious agents;
- Blocks the proliferation of viral cells;
- Resists the formation of pathologically altered cells.
The maximum level of interferons is observed in the patient’s blood 48 hours after taking a single dose of Kagocel. Interferons produced in response to the use of the drug circulate in the bloodstream for up to 4-5 days.
The drug itself penetrates the liver, lungs, spleen, lymph nodes and other organs. Most of The medication leaves the patient’s body after 7 days, mainly with feces. Only 10% of the medicine is excreted by the kidneys, so diseases of this organ do not affect the use of Kagocel.
The drug has no toxic effect and does not accumulate, and greatest effect from its use is noted in situations where treatment is started in the first 3-4 days infectious disease. If the tablets are used for prevention, they can be taken at any time, including the period after direct contact with a sick person releasing viruses.
Indications
Kagocel is prescribed for ARVI, herpes, influenza and other diseases caused by viruses. This drug is in demand in the treatment of sore throat, laryngitis, bronchitis and other diseases if they are caused by a viral infection. In addition, it can be prescribed as part of complex treatment rotavirus or enterovirus infection. The medication is also used to prevent infection with influenza viruses, rhinoviruses and other pathogens of acute respiratory infections.
Now let’s listen to Dr. Komarovsky about children’s acute respiratory infections and acute respiratory viral infections.
At what age is it allowed to take it?
In pediatrics, Kagocel is used in children over 3 years of age. It is not recommended to give this medicine to younger children (for example, if the child is only 2 years old). But even at the age of 3-5 years and older, you should not self-medicate with Kagocel. Before treatment with any antiviral drugs, you should consult your pediatrician to clarify whether there are indeed indications for such therapy.
Contraindications
The drug should not be taken:
- Children who are intolerant to any of its ingredients.
- Children with glucose-galactose malabsorption.
- For young patients with lactase deficiency.
- Adults during pregnancy and breastfeeding.
Side effects
As with the treatment of many other drugs, when using Kagocel, it is possible that allergic reaction. In addition to allergies, others negative consequences from these tablets are not mentioned.
Instructions for use and dosage
The tablets should be swallowed with water. It is not recommended to chew the medicine, and meals do not affect the mode of use of the drug in any way. WITH therapeutic purpose The following regimen for taking Kagocel is used:
- For children 3-6 years old, the medication is prescribed in a 4-day course. In the first two days, the child is given 1 tablet twice a day, and then for two days the child takes one tablet once. At this age, a total of 6 Kagocel tablets are given for the entire treatment period.
- If the child is over 6 years old, then a four-day course is also prescribed for treatment, however, the frequency of administration is different and the course dose will be higher. A single dosage is one tablet. On the first and second days of admission, the little patient is given it three times a day, and on the third and fourth days - twice. In total, the child receives 10 tablets of the drug over 4 days.
In order to prevent viral infections, the medication is childhood prescribed in a seven-day cycle. On the first day of treatment, a child over three years old is given 1 tablet of the drug per day, on the second day - another tablet of the drug once, and then Kagocel is not taken for five days, after which the cycle is repeated. The duration of such prophylactic use medication can last up to several months.
Overdose
Although Kagocel is considered a safe and non-toxic medicine, accidentally taking several tablets of such a medicine at once can lead to abdominal pain, dizziness, severe nausea and other signs of illness. Such an overdose requires prescribing plenty of fluids and inducing vomiting.
Interaction with other drugs
It is allowed to use other antiviral drugs together with Kagocel. This drug also works well with antibacterial agents and immunomodulatory medications, enhancing their effectiveness.
Terms of sale
To purchase a package of Kagocel in pharmacies, a prescription from your doctor is not required. The average price of 10 tablets is 220 rubles.
Storage conditions and shelf life
Kagocel should be kept at home away from sun rays and moisture. The medicine should not be in free access for small children, and the storage temperature should not exceed +25 degrees. If the shelf life of the tablets, which is 4 years, has expired, it is strictly forbidden to give such a drug to a child.
Reviews
In most cases, mothers who gave Kagocel to children or took such tablets on their own speak well of the medication. They emphasize the effectiveness of the medicine for colds and flu, since general state after the start of treatment, it improved and the disease passed faster. The medication is also praised for its minimum contraindications, small dosage and short course applications.
Explicit side effects children suffer from this medicine, judging by the reviews, are extremely rare. The drug is well tolerated even by children with allergies. Most parents consider the cost of medicine to be low, so rarely does anyone look for cheaper medicines. The release form does not cause difficulties for most patients. According to mothers, the tablets are easy to swallow and are not bitter.
As for the shortcomings of Kagocel, some reviews complain about its absence therapeutic effect, which is associated with the effect of the drug not on all types of viruses. There are also complaints that after a treatment course for a child under 6 years old, unused tablets remain. In addition, some mothers do not trust this medicine, since its composition has not been completely deciphered.
Analogues
The following drugs with antiviral and immunostimulating activity can replace Kagocel in case of viral diseases or for their prevention:
- Orvirem. This medicine in syrup is approved for children over 1 year of age. Thanks to the presence of rimantadine in its composition, the drug actively fights influenza and other acute respiratory infections caused by viruses.
- Amiksin. This antiviral drug in tablets contains tilorone. It is used in the treatment of influenza and other acute respiratory viral infections in children over 7 years of age.
- Viferon. The basis of such rectal suppositories is alpha interferon. The drug is prescribed for ARVI, rotavirus, candidiasis, influenza and many other diseases. It can even be used in premature newborns. The medication is also available in the form of a gel, approved from birth, and an ointment, prescribed to children over one year of age.
Associate Professor of the Department of Pediatrics-1 at Osh State University. Neonatologist-reanimatologist
RS OMKB. Candidate of Medical Sciences.
Kagocel with instructions for use is used for children as an antiviral and immunomodulatory medicine. Kagocel as an active substance is not used in other medicines; it is not included in the WHO registry. However, the drug is recognized as the most prescribed in Russia. How effective and safe is the drug, what do patients and doctors say about it?
According to the instructions, Kagocel is not used to treat children over 2 years of age. For patients younger age prescribe:
- Orvirem is a syrup with rimantadine. Prescribed to children over 1 year of age with the flu.
- – a product based on antibodies to human interferon gamma. The tablet is dissolved in a teaspoon of boiled water and can be taken from 1 month of life. Effective for acute respiratory viral infections, influenza, and intestinal infections.
- Cytovir-3 is available in powder form for solution preparation. Allowed for use from 1 year. The advantage of the drug is its use in children with atopic dermatitis. Prescribed for viral infections.
- – a flu medicine based on oseltamivir, prescribed from 1 year of age. Release form: capsules and powder for preparing a suspension.
The therapeutic course lasts 4 days:
- According to the instructions for children 3 years old, for the first two days Kagocel is taken 1 tablet twice a day.
- Then take 2 days, 1 tablet once a day.
6 tablets are taken per course of treatment. The medicine is used regardless of food intake.
If the child is 5 years old, then according to the instructions for therapeutic purposes, Kagocel is given in the same dosage as for children 3 years old. To prevent viral diseases, a seven-day cycle of taking the medication is used. On the 1st and 2nd days, the child should take 1 tablet, then take a break for 5 days. The course lasts from 7 days to several months. According to the instructions for use, Kagocel is used for prevention in children:
- during the seasonal spread of viral diseases;
- after contact with the patient.
In order to prevent infection, the drug is prescribed from 3 years of age, 1 tablet per day.
Kagocel, according to the instructions for use, for children over 6 years of age is prescribed in the following doses:
- the first two days, one tablet three times a day;
- for the next two days, take one tablet twice a day.
In just a four-day course of treatment, the child must take 10 tablets. The medicine is taken before or after meals.
For children aged 7 to 10 years and older, Kagocel is prescribed for therapeutic and for preventive purposes for ARVI and influenza. The same doses of the drug are observed as for a six-year-old child.
It is recommended to begin treatment with this remedy no later than the fourth day of illness. On at this stage The body already independently produces interferons of the required type and there is no need to take stimulants.
The medicine has round shape and cream color. Active substance– Kagocel, a synthetic interferon inducer. The product was developed by Russian scientists and has no analogues active substance. Among the auxiliary ingredients contains lactose.
Kagocel affects the cells that are responsible for immune reaction body to a viral attack. As a result, late interferon of the alpha and beta types is formed. This provides antiviral effect medicines.
After taking the medicine, the maximum production of interferons in the intestines is observed after 4 hours. Peak plasma concentrations are observed after two days. These indicators persist for another 4-5 days. Other organs into the tissues of which Kagocel penetrates:
- spleen;
- liver;
- The lymph nodes;
- kidneys;
- lungs.
This effect is recorded 24 hours after using the medicine orally. The substance is excreted approximately 90% through feces, and slightly less than 10% is excreted through urine.
Indications for prescribing Kagocel
- flu;
- acute respiratory viral infections;
- herpetic infections in adults;
- urogenital chlamydia (for adults, in combination with other medications).
It is possible to use the medicine for prevention during the seasonal spread of viral infections.
Contraindications
- children under 3 years of age;
- galactose intolerance;
- individual hypersensitivity to substances in the composition of the product;
- lactose intolerance Lapa;
- impaired absorption of glucose-galactose.
Kagocel is contraindicated for women during pregnancy and breastfeeding. This tool considered safe, but exceeding the dose may lead to stomach pain, severe nausea, dizziness and other signs of malaise. In this case, the patient needs to drink plenty of fluids and induce vomiting.
Adverse reactions and interactions with drugs
From side effects The drug is known to cause only rare development of allergic reactions.
Kagocel combines well with other medications that are prescribed for viral and bacterial infections. When interacting with antibiotics, immunomodulators, and antiviral agents, mutual enhancement of effectiveness was noted. According to the instructions, sedative effect Kagocel tablets for children do not have any properties.
Kagocel 12 mg - instructions for use for children
The concept of “children's Kagocel” does not exist, since a single release form is offered for children and adults - tablets, and a single dosage - 12 mg. To achieve a therapeutic effect, adults should take large quantity medicines. Recommended dosage regimen for Kagocel for adults:
- For acute respiratory viral infections and influenza - the first 2 days, 2 tablets. three times a day, then 2 days, 1 tablet. three times a day.
- Against herpetic infections and urogenital chlamydia are taken for 5 days, 2 tablets. three times a day.
The exact treatment regimen and dosage should be prescribed to the child by a pediatrician. Maximum daily dose should not exceed 24 mg for children under 6 years of age, 36 mg for children over 6 years of age. The minimum dose is 12 mg per 24 hours. Before taking the medicine, you need to be sure of the viral origin of the disease. For bacterial infections, Kagocel has an auxiliary immunomodulatory effect without eliminating the real reason illness.
Kagocel syrup - instructions for use for children
Kagocel for children is not produced in syrup form. The medicine is available only in 12 mg tablets. One package contains 10 pieces.
Kagocel - instructions for children and price
The price of Kagocel for children in Russia varies from 189 to 300 rubles per package.
Kagocel with instructions for use has been used to treat children recently, but there are many reviews about it. Opinions regarding the effectiveness and safety of the drug among patients and doctors are divided. From positive aspects use of the medicine is noted:
- The tablet is very small and easy for a child to swallow;
- The tablets only need to be taken for four days;
- no adverse reactions;
- one package of medicine is completely enough for the entire therapeutic course for a child;
- relief of well-being occurs already on the second day of taking the medicine;
- the drug is dispensed in pharmacies without a prescription;
- Compared to other immunomodulators, the price of Kagocel tablets for children is quite low.
For comparison, a number of drugs with similar effects and approximate prices:
- Tamiflu – 1270 rubles;
- – 990 rub.;
- Lavomax – 690 rub.;
- Viferon – 540 rubles;
- Tsitovir-3 – 390 rub.
Half of the patients were not satisfied with the experience of using Kagocel, even with a successful outcome of the disease.
Distrust of the drug is caused by:
- Presence of gossypol in the medicine. This substance is obtained from cottonseed oil. It can reduce the fertility of males, especially children. Gossypol is found in some male contraceptives. Since 1989, the WHO has banned the use of this substance in medicines. According to the manufacturer, gossypol in Kagocel is in a bound state, which ensures that it has no effect on the fertility of men and boys. However, there are no studies documenting its safety.
- Kagocel tests were carried out only in laboratory conditions on rats. To fully prove the safety and effectiveness of a substance, experiments on primates and, preferably, clinical studies are necessary. They are carried out on volunteers, with the participation of a control group taking a placebo. Nothing similar was done with Kagocel.
Consumers were also surprised by the latest metamorphoses with the medicine. Previously, according to the instructions for use, Kagocel could be prescribed to children from the age of six, but now it can be used from three.
According to reviews from doctors, there is no clear opinion about the instructions for using Kagocel for children. Some pediatricians trust the drug and prescribe it in combination with other medications for the treatment of ARVI and influenza. Some of their colleagues believe that the action of the drug is based on the placebo effect.
According to Dr. Komarovsky, among antiviral drugs, only drugs based on oseltamivir - Tamiflu, have proven effectiveness. This active substance has undergone many laboratory and clinical trials Worldwide. Other medications in this group cannot boast of such an evidence base.
In most cases of ARVI and influenza, Kagocel quickly eliminates the symptoms of the disease and shortens the treatment period. Before using the remedy, you need to consult a pediatrician and accurately establish the diagnosis.
Instructions for useKagocel® (Kagocel)Registration number: P No. 002027 dated 11/19/2007Trade name: Kagocel®Dosage form: tabletsComposition: active substance - Kagocel 12 mg. Excipients- potato starch, calcium stearate, Ludipress.Pharmacotherapeutic group: antiviral agent.Pharmacological properties: The main mechanism of action of Kagocel is the ability to induce the production of interferon. Kagocel causes the formation in the human body of the so-called late interferon, which is a mixture of alpha and beta interferons with high antiviral activity. Kagocel causes the production of interferon in almost all cell populations involved in the antiviral response of the body.Kagocel, when prescribed in therapeutic doses, is non-toxic, does not accumulate in the body. The drug does not have mutagenic and teratogenic properties, is not carcinogenic and does not have an embryotoxic effect. The greatest effectiveness in treatment with Kagocel is achieved when taken no later than the 4th day from the onset of acute infection. For preventive purposes, the drug can be used at any time, including immediately after contact with the infectious agent.Indications for use:Kagocel® is used in adults as a preventive and remedy for influenza and other respiratory viral infections, as well as a remedy for herpes.Kagocel® is used in children over 6 years of age as a treatment for influenza and other respiratory viral infections.Contraindications:Increased individual sensitivity, pregnancy, age up to 6 years.Directions for use and dosage:For the treatment of influenza and ARVI, adults are prescribed 2 tablets 3 times a day in the first two days, and one tablet 3 times a day in the next two days. A total of 18 tablets per course, course duration - 4 days. Prevention of respiratory viral infections in adults is carried out in 7-day cycles: two days - 2 tablets 1 time per day, 5 days break, then repeat the cycle. The duration of the preventive course is from one week to several months. For the treatment of herpes in adults, 2 tablets are prescribed 3 times a day for 5 days. A total of 30 tablets per course, course duration - 5 days. For the treatment of influenza and ARVI, children over 6 years of age are prescribed 1 tablet 3 times a day in the first two days, and one tablet 2 times a day in the next two days. Total for the course - 10 tablets, course duration - 4 days.Side effects:Perhaps the development of allergic reactions.Interaction with other drugs:Kagocel combines well with other antiviral drugs, immunomodulators and antibiotics.special instructions: To achieve a therapeutic effect, Kagocel should be started no later than the fourth day from the onset of the disease.Release form:Tablets containing 12 mg of the active substance. There are 10 tablets in total in a pack.Best before date:2 years. The drug should not be used after the expiration date indicated on the package.Conditions for dispensing from pharmacies:Dispensed without a doctor's prescription.
Antiviral and immunomodulatory drug.Drug: KAGOCEL ®
Active ingredient: non appropriated
ATX code: J05AX
KFG: Antiviral and immunomodulatory drug. Interferon synthesis inducer
Reg. number: P No. 002027/01
Registration date: 11/19/07
Owner reg. cred.: NEARMEDIC PLUS LLC (Russia)
DOSAGE FORM, COMPOSITION AND PACKAGING
? Pills round, biconvex, cream-colored, interspersed.
Excipients: potato starch, calcium stearate, ludipress (directly compressed lactose with the composition: lactose monohydrate, povidone (kollidon 30), crospovidone (kollidon CL)).
10 pieces. - contour cellular packaging (1) - cardboard packs.
The description of the drug is based on the officially approved instructions for use.
PHARMACHOLOGIC EFFECT
Antiviral and immunomodulatory drug. interferon synthesis inductor. The active substance is sodium salt copolymer of (1?4)-6-0-carboxymethyl-?-D-glucose, (1?4)-?-D-glucose and (21?24)-2,3,14,15,21,24, 29 ,32-octahydroxy-23-(carboxymethoxymethyl)-7,10-dimethyl-4, 13-di(2-propyl)-19,22,26,30,31-pentaoxaheptacyclo dotriaconta-1,3,5(28), 6.8(27), 9(18),10, 12(17), 13.15-decaene.
Causes the formation in the body of so-called late interferon, which is a mixture of alpha and beta interferons with high antiviral activity. Kagocel causes the production of interferon in almost all cell populations involved in the body's antiviral response: T- and B-lymphocytes, macrophages, granulocytes, fibroblasts, endothelial cells. When one dose of Kagocel is taken orally, the interferon titer in the blood serum reaches maximum values after 48 hours. The body's interferon response to Kagocel administration is characterized by prolonged (up to 4-5 days) circulation of interferon in the bloodstream. The dynamics of interferon accumulation in the intestine when taking the drug orally does not coincide with the dynamics of circulating interferon titers. In the blood serum, the content of interferon reaches high values only 48 hours after taking Kagocel, while in the intestine the maximum production of interferon is noted already after 4 hours.
Kagocel, when prescribed in therapeutic doses, is non-toxic, does not accumulate in the body. The drug does not have mutagenic and teratogenic properties, is not carcinogenic and does not have an embryotoxic effect.
PHARMACOKINETICS
Suction and distribution
When taken orally, about 20% of the administered dose of the drug enters the general bloodstream. After oral administration after 24 hours, it accumulates mainly in the liver, to a lesser extent - in the lungs, thymus, spleen, kidneys, and lymph nodes. Low concentration is observed in adipose tissue, heart, muscles, testicles, brain, blood plasma. The low content in the brain is due to the high molecular weight of the drug, which hinders its penetration through the BBB. In plasma, the drug is found predominantly in bound form: with lipids - 47%, with proteins - 37%. The unbound portion of the drug is about 16%. With repeated daily administration of the drug, V d varies widely in all organs studied, the accumulation of the drug in the spleen and lymph nodes is especially pronounced.
breeding
It is excreted mainly through the intestines: 7 days after ingestion, 88% of the administered dose is excreted from the body, including 90% with feces and 10% with urine. The drug was not detected in exhaled air.
INDICATIONS
Prevention and treatment of influenza and other acute respiratory viral infections in adults;
Treatment of influenza and other acute respiratory viral infections in children aged 6 years and older;
Treatment of herpes in adults.
DOSING REGIME
For adults
For treatment of influenza and ARVI prescribed in the first 2 days - 2 tablets. 3 times a day, in the next 2 days - 1 tablet. 3 times/day. In total, for a course lasting 4 days - 18 tab.
Prevention of ARVI carried out in 7-day cycles: 2 days - 2 tablets. 1 time/day, break for 5 days. Then the cycle is repeated. The duration of the preventive course varies from 1 week to several months.
For herpes treatment 2 tablets are prescribed. 3 times/day for 5 days. In total, for a course lasting 5 days - 30 tablets.
Children aged 6 years and older
For treatment of influenza and ARVI prescribed in the first 2 days - 1 tablet. 3 times a day, in the next 2 days - 1 tablet. 2 times/day. A total of 10 tablets per course lasting 4 days.
SIDE EFFECT
Maybe: allergic reactions.CONTRAINDICATIONS
Pregnancy;
Children under 6 years of age;
Increased individual sensitivity.
PREGNANCY AND LACTATION
The drug is contraindicated for use during pregnancy.
SPECIAL INSTRUCTIONS
The greatest effectiveness in treatment with Kagocel is achieved when it is prescribed no later than the 4th day from the onset of acute infection. For prophylactic purposes, the drug can be used at any time, incl. and immediately after contact with an infectious agent.
Kagocel combines well with other antiviral drugs, immunomodulators and antibiotics.
OVERDOSE
Treatment: In case of accidental overdose, it is recommended to prescribe plenty of fluids and induce vomiting.DRUG INTERACTIONS
With simultaneous use of Kagocel with other antiviral drugs, immunomodulators and antibiotics, an additive effect has been described.
CONDITIONS OF VACATION FROM PHARMACIES
The drug is approved for use as a means of OTC.
TERMS AND CONDITIONS OF STORAGE
The drug should be stored in a dry place, protected from light, out of reach of children, at a temperature not exceeding 25°C. Shelf life - 2 years.
