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Ureaplasma disease symptoms. What causes ureaplasma urealyticum? Routes of transmission of ureaplasma

Ureaplasma is an opportunistic flora that is sexually transmitted through unprotected intercourse from a carrier or sick person to a healthy person.

If you have a strong enough immune system that performs the body’s protective functions, ureaplasma may never manifest itself.

But if the level of immunity is at its lowest level, and various associated factors (viral or infectious disease) have appeared, ureaplasma can be activated and cause inflammation genitourinary system.

Ureaplasma affects a healthy person not only during sexual intercourse, but can also be transmitted intrauterinely from an infected mother to the fetus. Postpartum infection of the baby is also possible, when during childbirth the child passes through the infected birth canal. IN medical practice The oral-genital method of transmission of infection is also common.

Today, there are two types of the causative agent of ureaplasmosis:

  • Ureaplasma parvum.

Provoking factors for the activation of ureaplasma are various related aspects. First of all, this is too early sexual activity and a large number of sexual partners with whom unprotected contact occurs.

Disease provocateurs are also venereal diseases sexually transmitted viruses. In some cases, the problem lies in a not very effective and quality treatment gynecological disease, as a result of which an infection appears in the body, causing the disease. Ureaplasma can also be provoked by a course of treatment with antibiotics, with which you treat various diseases. The antibiotic disrupts the microflora and leads to some hormonal imbalances in the body, weakens the immune system.

Another important factor is stress and nervous tension, which provoke the most various diseases, including ureaplasma. After you become infected with ureaplasma, you will not immediately see symptoms of the disease, since the incubation period of the microorganism can last a very long time, and during this time you become a carrier of the infection, which you pass on to your sexual partners.

As a rule, the incubation period can last from 2 to 4 weeks. At this time, the inflammatory process begins, and the infection spreads further, causing negative impact on the genitourinary system, as a result of which the disease begins to show symptoms.

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If you have a fairly satisfactory level of immunity, the disease will not be accompanied by obvious symptoms and develops into a chronic form. And this already poses a health hazard, since ureaplasma provokes the development of serious diseases with complications. May be affected nervous system, joints, any other organ.

Ureaplasmosis: symptoms and methods of transmission of the disease

The disease ureaplasmosis manifests symptoms in men and women almost equally.

In women, many diseases that are sexually transmitted can be completely asymptomatic without menstrual irregularities, pathological discharge from the vagina, or pain in the lower abdomen.

But when immunity is at a poor level, pregnancy begins and other negative and accompanying factors are present, then the symptoms of ureaplasmosis begin to manifest themselves. Note that many of the symptoms characteristic of ureaplasmosis are similar to many sexually transmitted diseases.

Ureaplasmosis in women has the following symptoms:

  • Transparent discharge from the vagina, not accompanied by odor. Over time, the discharge may take on a dirty yellow or greenish color and have an unpleasant odor. These symptoms already indicate that an inflammatory process has begun, which can develop into a chronic one.
  • Pain in the lower abdomen indicates that ureaplasmosis begins to cause inflammation in the uterine appendages.
  • If there was an oral-genital method of contracting the infection, then a sore throat may develop, the tonsils become covered with a whitish, purulent coating.
  • Appears when urinating sharp pain and burning, the urge to urinate also becomes more frequent.
  • During sexual intercourse, pain in the vagina may also be present.

In any case, women should be examined not only when they notice unpleasant symptoms of ureaplasmosis, but regularly - preferably once every six months - to prevent the development chronic diseases caused by ureaplasma. You may not have significant symptoms, but you may be a carrier of the infection and pass it on to your partner.

More about the disease

Symptoms of ureaplasmosis in men are as follows:

  • non-gonococcal urethritis develops;
  • cloudy discharge comes from the urethra;
  • objective symptoms may be absent (pain when urinating, frequent urge to urinate);
  • discharge may appear and disappear, then manifest itself again;
  • inflammation of the testicle develops.

The consequences of the lack of adequate treatment can manifest themselves in damage to the genitourinary system, infertility, and joint tissue. Treatment of the disease begins with diagnosis using culture and PCR. The doctor, based on these tests, prescribes a therapy that will make it impossible for the infection to develop and spread in the body. For improvement general condition health are assigned special drugs to correct immunity, suppress infection and get rid of other infectious and viral diseases that reduce the level of immunity.

Based on culture data, the doctor determines the level of sensitivity of pathogenic microflora to different types of antibiotics in order to prescribe the most effective drug and select the optimal and individual treatment regimen for the patient.

In addition to a variety of specific medications, immunostimulants and bactericidal agents are also prescribed local action, the use of physiotherapy. One of the most important conditions for recovery is the treatment of not one, but two sexual partners in order to rid their bodies of the presence of the problem and re-infection. During the treatment process, you should not be sexually active; you need to use a special diet and follow all the recommendations of your doctor.

What diseases does ureaplasma provoke in women and men?

Ureaplasma in women can occur with symptoms and asymptomatically, if there are no negative factors activating inflammatory processes. Therefore, the gynecologist always recommends visiting him at least once every six months in order to conduct examinations to identify all, even hidden problems, infections, viruses.

If you don't carry out adequate treatment, ureaplasma in women can develop into a chronic form and cause various complications.

When a chronic process begins, then the harmful microflora of ureaplasma remains on the walls of the mucous membrane of the genital organs and at any time, under unfavorable conditions, it can be activated and cause inflammation, exacerbation, and damage to the urinary tract. Vaginal discharge may have no color or odor, but this may already indicate the presence of an infection that can lead to such negative consequences, such as infertility, complete impossibility of conception, miscarriage of the fetus different dates pregnancy.

Strong provocateurs of infection include colds, stress, low immunity, viral problems, increased physical activity and other aspects. Therefore, ureaplasma in men and women poses a certain danger and should be treated. With untimely and inadequate treatment, pathogenic microflora causes urolithiasis, colpitis, cystitis, endodermatitis, and arthritis. If the infection process goes too far, then ureaplasmosis can cause infertility in women, as adhesions occur in the appendages and uterus.

If ureaplasmosis is activated during pregnancy, it can cause miscarriage or premature birth. Treatment of ureaplasmosis in women is carried out only according to the recommendations and under the supervision of a doctor. The most effective is antibacterial therapy. In this case, the doctor determines the antibiotic that is optimally suited to the individual characteristics of the patient, her body and the course of the disease. The regimen and dosage of the drug is chosen by the doctor. In combination with antibacterial therapy, local treatment with vaginal suppositories is also carried out.

Immunomodulatory medications are also used, which prevent further development of pathogenic vaginal flora and gastrointestinal tract(due to taking antibiotics). It is necessary to temporarily abstain from intimate relationships for the duration of treatment so as not to injure the mucous membranes of the genital organs. If a pregnant woman is being treated, then therapy begins only after 22 weeks of pregnancy. In most cases, therapy lasts up to 2 weeks.

As a preventive measure, normal intimate life with one partner, use protective equipment and periodically visit a doctor and get tests.

Ureaplasma occurs as often in men as in women. The course of the disease can also be asymptomatic early stages when there are no activation factors. And this is the main danger, since when symptoms appear, they indicate those complications and diseases that were provoked by ureaplasmosis. The first signs may appear several months after infection. Most often, ureaplasma in men causes pain and burning during urination, secretion, and inflammation of the urethra.

A common manifestation of the problem is urethritis, which is accompanied by sharpness and pain, burning and discomfort when urinating. Very rarely, the disease goes away on its own, but most often it becomes chronic with periodic exacerbations, which negatively affect the quality of life. or inflammation of the epididymis is rare, but quite possible. The disease is not accompanied by any discomfort and painful sensations, but the appendage thickens and enlarges.

These symptoms force a man to visit a urologist, and then he will find out what is causing the problem. Prostatitis can have the most different reasons occurrence, including ureaplasmosis in men. The symptoms of the disease remain the same pain when urinating, burning and discomfort in the perineal area. If left untreated, the disease leads to impotence and male infertility.

Therapy for ureaplasma in women and men is the same; an individual treatment regimen using antibiotics and immunostimulants is also being developed. If one type of drug does not provide quick and effective results, it is replaced with adequate drugs with more effective action. Prevention of the disease should be carried out constantly, especially if you are sexually active, then your partner should also undergo examinations.

Ureaplasmosis: treatment with antibiotics and folk remedies

If you have been diagnosed with ureaplasmosis, treatment is carried out using innovative drugs that give effective results.

This disease should be treated in the following cases:

  • When studies and symptoms show that there is an inflammatory process in the body, which can cause the development of complications and other diseases of the genitourinary system.
  • If you are a sperm donor.
  • For those women who have a history of a diagnosis of infertility and have the opportunity to resolve this issue positively.
  • Before planning a pregnancy.

Doctors use A complex approach to treatment, since it is necessary to get rid of pathogenic microflora, have a local effect on foci of inflammation and increase the level of immunity.

Antibiotic therapy is considered the most effective. This virus has one bad property - it can mutate and cannot be treated with antibiotics. Therefore, treatment is carried out under the supervision of a doctor even if the therapy does not give desired results, then the antibiotic is replaced with another. To test the propensity of this harmful microorganism to antibiotics and a culture is carried out, which shows which groups of antibiotics can cope with the problem and destroy the infection. Antibiotics of the macrolide group are most often used because... They can cope with the microorganism; fluoroquinols are also effective.

It is very important to carry out a full course of therapy, which will completely cleanse the body of the presence of infection and you will no longer have to worry about relapses and acute forms of the disease. You can help yourself using folk remedies. In this case, medicinal herbs are used that have antibacterial, immunostimulating, and cleansing properties. Perfect fit medicinal fees, from which you will make infusions and decoctions.

Suitable medicinal herbs:

  • chamomile;
  • licorice;
  • Leuzea;
  • alder cones;
  • penny root;
  • series;
  • wild rosemary;
  • yarrow;
  • burnet;
  • lungwort;
  • violet;
  • thyme;
  • wild rosemary;
  • plantain.

You can make up decoction from several herbs, take 1 tablespoon each, pour boiling water and leave for 40 - 60 minutes. The infusion is filtered and consumed before meals (30 minutes before) 2 times a day, half a glass. Insufficient treatment of ureaplasmosis can lead to the most different consequences. If there is no treatment, the problem subsides, and after a certain period of time it manifests itself in an acute form and this can last indefinitely.

Ultimately, the disease leads to problems such as impotence, infertility, other severe pathologies, problems during childbirth and miscarriages. In addition to the great danger posed by ureaplasma present in your body, other negative changes may occur. For example, the progression of diseases from mild to severe and chronic forms.

Varieties

Very often, this infection can be combined with other viruses and diseases in your body. For example, this could be chlamydial and gonococcal lesions, the presence of Trichomonas, etc. When these infections mix, the result is an acute and severe course of the disease, which has a very negative impact on overall health. Treatment of such infections takes a very long time and it is necessary to use strong drugs wide spectrum of action.

The presence of an infection in the body often indicates that the patient has a very low level of immunity and this indicates that the body can easily “catch” any infectious and viral disease, which will complicate the health condition. Therefore, it is so important to start treating this problem - ureaplasmosis, as early as possible, use effective medications, and follow all the doctor’s recommendations.

Ureaplasmosis during pregnancy and the effect of the disease on the fetus

Ureaplasmosis during pregnancy poses a risk of infection for the unborn baby.

The difficulty of diagnosing an infection at this point is that the main symptoms - vaginal discharge - are characteristic of pregnancy and ureaplasmosis. And in some cases, infection is completely asymptomatic. Therefore for accurate diagnosis You should undergo an examination so as not to aggravate your condition and take timely treatment measures. If the problem is not noticed in time, then cramps and pain in the abdomen are added to the discharge, which causes severe discomfort and fears for the fetus. Any infection and ureaplasmosis during pregnancy is a risk of losing a child or giving birth to him with various pathologies. The percentage of miscarriages diagnosed with ureaplasmosis today is up to 35%.

The presence of infection in the weakened body of a pregnant woman helps other viruses penetrate the body and cause diseases, disturbances in the growth and development of the fetus. Previously, such a diagnosis as ureaplasmosis during pregnancy could serve as an indicator for its termination, since the infection infects the fetus, which leads to serious consequences and pathologies. Today, the treatment of various infectious and viral diseases, as well as ureaplasmosis before conceiving a child and during pregnancy, is effectively treated.

If infection occurs in the first trimester of pregnancy, the mother’s body protects the fetus from infection. But the infection itself negatively affects the condition of the walls of the uterus - it causes them to loosen, which is the cause of miscarriage or premature birth. In this case, the walls of the uterus are sutured so that they remain in good shape and the risk of premature termination of pregnancy is reduced.

Ureaplasma therapy is carried out with antibiotics and therefore, in order not to harm the development of the fetus, treatment of a pregnant woman with these drugs begins at 22 weeks of pregnancy. It is at this time that the fetus is already reliably protected, it has good immunity and that’s it. internal organs are already developing. In parallel with antibiotics, immunostimulating agents are also prescribed, which increase the body’s protective functions and prevent the risk of infection with other diseases.

Ureaplasmosis in an “interesting” position during pregnancy is dangerous, so before conceiving you should undergo all the necessary examinations, and if the infection is diagnosed, you must get rid of it immediately.

To date, ureaplasmosis has not yet been well studied, and no doctor can predict the course of pregnancy with such a diagnosis; a variety of scenarios for pregnancy, childbirth, and postpartum complications are possible. Treat your health carefully and attentively, as ureaplasmosis can often be diagnosed during pregnancy. Infection also occurs during pregnancy, so avoid situations in which you can become infected with unwanted viruses and infections.

The causative agent of this disease is the microorganism ureaplasma, which belongs to intracellular microbes. Ureaplasmosis tends to be chronic.

Causes

The causes of ureaplasmosis in both women and men can be:

  • frequent change of sexual partners;
  • unprotected sex;
  • lack of personal hygiene;
  • infection of the fetus from the mother.

The most favorable factor in the development of this disease is a decrease in immunity, which can be caused by low-quality and insufficient nutrition, bad habits, past viral disease, nervous disorders and constant stress, the use of antibacterial and hormonal drugs, radioactive exposure.

Symptoms

Ureaplasmosis may not bother you for a long time. The incubation period of this disease is 7-14 days. The absence of symptoms of ureaplasmosis can in some cases lead to the disease becoming chronic and causing serious health consequences.

The symptoms of ureaplasmosis are not very specific and are similar to the manifestations of other diseases that are transmitted during sexual intercourse.

Symptoms of ureaplasmosis in men

  • scanty discharge from the urethra;
  • burning and pain in the penis area, which intensifies during sexual intercourse or urination;
  • soreness in the scrotum area;
  • impaired sperm quality;
  • discomfort and prolonged nagging pain in the depths and lower abdomen and in the perineum.

Symptoms of ureaplasmosis in women

  • burning and pain during urination;
  • vaginal discharge;
  • the presence of scant bloody discharge from the vagina after sex;
  • pain in the lower abdomen;
  • pain during sex;
  • difficulty conceiving.

Treatment of ureaplasmosis


Treatment scheme. Drugs used.

Treatment regimens for this disease are similar in women and men. Only a doctor can prescribe treatment. In most cases, specialists prescribe tetracycline antibiotics. If ureaplasma resistance to this group is detected, the drugs can be replaced with macrolides or fluoroquinolones. Sometimes treatment requires the use of 2 antis at the same time. bacterial agents from different groups.

After antibiotic therapy, for the prevention and treatment of dysbiosis, it is recommended to take drugs that normalize the intestinal microflora. To strengthen the immune system, patients are prescribed natural immunomodulators (schisandra, echinacea extract, rosehip syrup and decoction) and multivitamin preparations. After completing therapy, you should undergo a follow-up examination.

Treatment of ureaplasmosis with folk remedies.

Treatment of ureaplasmosis with the help of folk remedies is usually resorted to if taking medications according to various reasons undesirable.

There are a large number of home recipes for treating this disease, but the most effective is the collection, which is based on Deryabin’s recipe. This collection will help normalize the acid balance; it has diuretic, anti-inflammatory and immunostimulating properties. To prepare it, you need to take all the following ingredients in equal proportions:

  • pine and Birch buds;
  • flowering of chamomile, immortelle, calendula and linden;
  • dandelion, valerian and burnet roots;
  • leaves of oregano, dried cucumber, mint, motherwort, celandine, thyme, St. John's wort and sage;
  • leaves of nettle, coltsfoot and plantain.

All ingredients must be mixed and ground. Next, take 2 tablespoons of powder from the resulting mass and pour boiling water over it. Then you need to close the lid tightly and leave overnight. For a three-month course, you should consume 3-4 glasses per day.

Garlic paste can be a good help in treating the disease. To do this, you need to finely chop 10 grams of garlic and mix with the same amount of sunflower oil. Add a teaspoon of iodized salt and a tablespoon of lemon juice with zest to the resulting mixture. Next, the mixture must be thoroughly beaten. The paste should be taken orally after meals.

Treatment of ureaplasmosis folk ways good to reinforce with douching. To do this, you can prepare a decoction of 1 part boron uterus, 2 parts dried oak bark, 1 part Kuril tea and 1 part bergenia root. The collection needs to be filled hot water and cook, bringing to a boil, for half an hour. Then let it brew for a couple of hours.

Diagnosis of ureaplasmosis

In order to detect the presence of ureaplasma, specialists use a whole set of diagnostic methods.

The classic method for diagnosing the disease is bacterial culture for ureaplasmosis, in which the biomaterial is placed in a favorable environment for the propagation of pathogenic microorganisms. The material for analysis can be urine, blood, sputum, prostate secretions, pathological fluids, scrapings of epithelial cells, serum.

Another method is PCR. This is the most sensitive and exact method, which allows you to identify the causative agent of the disease by the presence of its DNA. Ureaplasma is diagnosed using material obtained from cervical canal, vagina, urethra.

Determination of antibodies to the disease is possible using the serological method. The material for the study is deoxygenated blood, taken from the ulnar vein in the morning, on an empty stomach.

Consequences of ureaplasmosis

The main danger of this disease is that it is often asymptomatic, but can affect almost all areas of the genitourinary system. If a woman long time does not treat ureaplasmosis, it can cause:

  • cervicitis (inflammation of the cervical mucosa);
  • vaginitis (inflammation of the vagina);
  • (inflammation in the area of ​​the ovaries and uterine appendages);
  • endometritis (damage to the lining of the uterus);
  • salpingitis (damage to the fallopian tubes).

The latter disease not only causes physical discomfort to a woman, it can also cause ectopic pregnancy and infertility.

Men are less susceptible to uraeplasmosis. They exhibit symptoms of this disease less frequently than women, as a result of which the disease can progress for a long time before making itself felt. Ureaplasmosis in men can cause:

  • prostatitis (inflammation of the prostate gland);
  • urethritis (inflammation of the urethra, accompanied by discharge and itching when urinating);
  • disorders of spermatogenesis (sperm activity decreases).

Useful video

How to protect yourself from ureaplasmosis - advice from Elena Malysheva.

New medical research technologies such as polymerase chain reaction and enzyme-linked immunosorbent assays have enabled the identification of many new microorganisms. Among them is ureaplasma (Ureaplasma urealyticum).

Many patients who have been diagnosed with ureaplasmosis are interested in the type of pathogen, asking questions about how dangerous ureaplasma is, what it is and how to quickly recover from the disease.

The bacterium lives on the genitals and in urinary system person. Bacteriological studies reveal the activity of the microorganism in various diseases inflammatory in nature: prostatitis, cystitis, colpitis, adnexitis, cervical erosion and other genitourinary diseases in men and women.

The microorganism penetrates into the cytoplasm of leukocytes, epithelium, sperm, disrupting their functions. Often ureaplasma is found together with other pathogenic microflora: chlamydia, gardnerella, trichomonas and others.

Symptoms of the disease may appear acutely or be indolent. There are no specific symptoms unique to ureaplasmosis. Symptoms of the disease caused by ureaplasma are easily confused with manifestations of other microbes. It is possible to determine specifically whether it is ureaplasma or, for example, chlamydia, using diagnostic studies.

WE ADVISE! Weak potency, a flaccid penis, lack of a long-term erection are not a death sentence for a man’s sex life, but a signal that the body needs help and male strength is weakening. There are a large number of drugs that help a man gain a stable erection for sex, but they all have their own disadvantages and contraindications, especially if the man is already 30-40 years old. help not only to get an erection HERE AND NOW, but act as a preventive measure and accumulation of male power, allowing a man to remain sexually active for many years!

Symptoms of male ureaplasmosis:

  • burning and stinging in the genitals during urination;
  • painful sensations in the area of ​​the head of the penis during sex;
  • nagging pain in the perineum and lower abdomen;
  • pain in the scrotum (testicles);
  • Not copious discharge from the genital organ;
  • decreased sexual desire.

Symptoms of female ureaplasmosis:

  • there is pain, burning and stinging when urinating;
  • nagging pain in the lower abdomen may appear;
  • there is copious vaginal discharge;
  • a woman experiences discomfort during sex;
  • partial or complete lack of libido;
  • after sexual intercourse, blood may appear in the discharge;
  • Pregnancy does not occur for a long time.

Ureaplasma can cause harm to the body without symptoms. In this case, the disease enters the chronic stage, bypassing the acute stage.

How is ureaplasma transmitted, and what factors contribute to the development of diseases?

The main routes of transmission of Ureaplasma spp are considered to be unprotected sexual contact, and infection of infants from the mother in utero or during passage through the birth canal. Intrauterine infection is possible due to the presence of ureaplasma in the amniotic fluid. The infection enters through the skin, urethrogenital tract or digestive tract.

According to statistics, almost a third of female newborns have ureaplasma on their genitals. Among boys, this figure is much lower. As the body grows and develops, the infection disappears, especially in male children. Among schoolgirls, ureaplasma is detected in only 5 to 20 percent of those examined. For boys, this figure is practically reduced to zero. Unlike children, the percentage of adults suffering from ureaplasmosis is increasing, since the sexual route of infection is the most common.

Another way of transmitting a microorganism is through household. How ureaplasma is transmitted through household contact has not been studied, so this statement is controversial. But there are still prerequisites for the fact that not only sexual intercourse is the cause of infection in adults. For example, the microbe is able to remain active on damp household items for two days.

Frequently asked questions about methods of transmission of a microorganism:

  • Is it possible to become infected with ureaplasma through a kiss?
    Microbes live and multiply on the organs of the genitourinary system. They are not in the mouth. Therefore, a kiss cannot be a source of infection with ureaplasmosis. But if partners engage in oral sex, the microorganism, entering the oral cavity, can be transmitted to the partner through a kiss. And if he has ulcers on the mucous membranes, then ureaplasma can enter the bloodstream, and, accordingly, infection is possible.
  • Is ureaplasma transmitted through saliva?
    We have already found out how ureaplasma is transmitted through a kiss. Therefore, we can say that saliva itself does not contain a microbe, but it can temporarily appear in its composition during oral sex.

If an infection enters the body, this does not mean that the person will get sick.

To activate ureaplasma, special conditions are required, including:

  • reduced immunity;
  • frequent stress;
  • imbalance of the body's microflora;
  • the presence of other infections of the genitourinary system;
  • radioactive exposure;
  • poor nutrition and quality of life in general;
  • insufficient genital hygiene;
  • long-term use of antibiotics or hormonal drugs;
  • pregnancy, childbirth.

A decrease in the body's defenses is almost always accompanied by the development or exacerbation of diseases of bacterial etiology. But the illnesses themselves also reduce immunity: frequent colds, chronic diseases, etc. During pregnancy, a woman’s body undergoes restructuring, and this puts an additional burden on the immune system.

Poor nutrition, alcohol abuse, heavy physical activity and stress - all lead to exhaustion of the body, and therefore contribute to the development of ureaplasmosis. Most dangerous factor For the manifestation of the disease are promiscuous sexual intercourse.

In addition to the many different pathogenic microorganisms that enter the mucous membranes of the genital organs, frequent changes of sexual partners disrupt the natural microflora present in the genitourinary area of ​​a woman, increasing the risk of developing inflammatory processes.

Types of ureaplasma in women and men

Ureaplasmas have recently begun to be isolated from separate species microorganisms. Previously, they were classified as a class of mycoplasma. Among the species are ureaplasma urealiticum, parvum and spices. Latin names: urealyticum, parvum, species. There are 14 types of microorganisms in total, but only three by type, differing in the composition of membrane proteins. Thanks to typing by type, it is possible to select an effective treatment for ureaplasmosis.

Type urealiticum.

It has a weakly expressed membrane, due to which it easily penetrates into the mucous membranes of the genital organs and urinary tract. This type of ureaplasma is capable of destroying immune cells, since the basis of the microorganism is immunoglobulin Iga. But most great danger The microbe urealyticum is that it penetrates the cytoplasm of sperm and blood, destroying them.

A variety of parvum.

Spice type

Treatment varies depending on the type of microbe. The most commonly diagnosed diseases are those caused by ureaplasma urealyticum and parvum. Usually the second does not require treatment, it all depends on the number of microbes living on the mucous membranes.

If ureaplasma pravum exceeds permissible norm several times, then inflammation develops and antibacterial therapy is carried out against the bacteria. The urealiticum type requires rapid intervention, as it can cause complications. Based on the patient’s complaints, molecular PCR diagnostics are performed, and after detecting a type of microorganism, appropriate treatment is prescribed.

It is especially important to diagnose these types of ureaplasma in women while pregnant, as they disrupt the normal process of pregnancy.

Tests to identify spices are prescribed in the following cases:

  • pregnancy is planned;
  • there are pathologies from previous pregnancies;
  • during infertility treatment;
  • the presence of urogenital infections.

Ureaplasmosis is treated with antibacterial therapy. The antibiotics usually prescribed are tetracyclines or macrolides: Azithromycin, Doxycycline, Josamycin and others. As a supplement, a course of treatment with immunomodulators is prescribed: Dikaris, Taquitin, etc. While taking medications, sexual intercourse and drinking alcoholic beverages are prohibited. Pregnant women undergo therapy under the supervision of a physician.

Diseases caused by different types of ureaplasma in women and men:

  • women: damage to the fallopian tubes, adnexitis, endometriosis, cervicitis, vaginitis, ectopic pregnancy, infertility;
  • men: prostatitis, urethritis, infertility.

Ureaplasma infection: diagnosis and characteristics of the disease during pregnancy

Treatment of ureaplasmosis is possible only after diagnostic studies. As mentioned earlier, the disease has no distinctive symptoms, and, therefore, the pathogen that provokes the inflammatory process must be identified. It is advisable to undergo diagnostics before conceiving a child, since bacteria can infect the fetus.

Ureaplasma infection is detected using different methods:

  1. Enzyme-linked immunosorbent assay (ELISA). It can be used to differentiate the types of infection: Ureaplasma urealyticum and pravum. The method allows you to detect antibodies to the microbe and titer (quantity) of bacteria.
  2. Cultural method (bacterial inoculation). A longer method, but with increased accuracy. Allows you to identify the type of pathogen and its sensitivity to antibacterial substances.
  3. Polymerase chain reaction (PCR). Quite an expensive method. It can be used to detect even small amounts of bacteria or viruses in blood serum long before clinical manifestations diseases.
  4. Immunofluorescence (RNIF - indirect, RPIF - direct). One of the most inexpensive methods for identifying pathogenic microflora.

Late diagnosis before pregnancy or infection during pregnancy can cause various complications. This is especially dangerous in the 1st trimester, since antibacterial therapy cannot be carried out during this period. Antibiotics can harm the fetus by inhibiting its growth and causing developmental abnormalities.

Complications associated with pregnancy:

  • Ureaplasma urealyticum can lead to ectopic pregnancy, and early stages- provoke a miscarriage.
  • On later subspecies Ureaplasma spensis contributes to premature birth.
  • Both during pregnancy and during childbirth, the baby can be infected with bacteria.
  • Ureaplasma infection can cause inflammatory processes in the uterus, which negatively affect the process of bearing a child.
  • Many doctors associate low baby weight after birth with the presence of Ureaplasma urealyticum. But it is too early to claim this as a fact, since research is ongoing.

Ureaplasmosis is an infectious disease of the genitourinary system, which is of a bacterial nature and provoked by a pathogen called ureaplasma. The latter belongs to the category of opportunistic microorganisms, i.e. it can be present in the human body without causing any problems or inconvenience until certain provoking factors arise, for example, a decrease in protective functions, artificial termination of pregnancy, unsuccessful use of intravaginal contraceptives, and even simply against the background of common common diseases or normal menstruation.

Ureaplasma in women - manifestations and treatment

Having received one of the above “shocks”, ureaplasma begins to destroy membranes healthy cells, provoking the appearance of signs of inflammatory processes. The infection may be characterized acute course and become chronic.

Symptoms are usually vague. The main problem of ureaplasmosis is that it may not manifest itself in any way, i.e. Patients often have no idea about the presence of the disease, but are already carriers of it and pose a danger to their sexual partners.

Quite often, ureaplasmosis is diagnosed in combination with diseases such as chlamydia, trichomoniasis and other common diseases of the genitourinary system.

Transmission of ureaplasma in the vast majority of cases occurs during sexual contact with an infected person. It is possible for the fetus to become infected by an infected mother. Household transmission infection is extremely unlikely.

You have received basic information about such a disease as ureaplasmosis. Next, you are invited to familiarize yourself with the peculiarities of its manifestation in women, as well as study information about methods for diagnosing the infection and subsequently getting rid of it.

As noted, the disease may not manifest itself in any way for a fairly long period (up to several months or even more). Menstrual irregularities, painful and uncomfortable sensations, vaginal discharge– although all this is characteristic of ureaplasmosis (in principle, as for most other diseases of the genitourinary system), it may be absent.

In many situations, symptoms and signs appear only when exposed to unfavorable factors, a list of which was given earlier. Features of the manifestation of “female” ureaplasmosis are presented in the following table.

Table. Symptoms and signs of ureaplasmosis in female patients

List of signs and symptomsExplanations

As a rule, they are quite scarce, odorless and colorless. Along with this, if the inflammatory process has already started, the discharge may become sharp. bad smell and change color to greenish or yellow.

As a rule, they are localized in the lower abdomen and appear as a cutting type. In this case, ureaplasmosis most likely caused complications on the appendages and uterus.

If the infection occurs during oral sex, signs characteristic of a sore throat may appear: plaque on the tonsils (tonsils), pain in the oropharynx, difficulty swallowing, etc.

The urge to empty the bladder becomes more and more frequent, accompanied, at the same time, by painful sensations, stinging, and burning.

It becomes painful and uncomfortable for the patient to have sex. Unpleasant sensations appear during sexual intercourse and persist after it is completed.

Important! Be sure to go to the doctor after unprotected sexual contact with an unverified partner, if such a relationship has occurred. Even if ureaplasmosis remains asymptomatic, it can lead to many serious adverse consequences.

So, if the disease becomes chronic, pathogenic microorganisms attach themselves to the mucous membranes of the genital organs and simply wait for a “push to activation.” As a last resort, in the presence of chronic ureaplasmosis, even a common cold, severe stress or heavy physical exertion will be enough.

Depending on the intensity of manifestation and stage of progression of ureaplasmosis, in combination with the above symptoms, other unfavorable signs characteristic of inflammatory diseases and intoxication lesions.

Left unattended, ureaplasmosis will most likely lead to severe complications in the form of cystitis, colpitis, urolithiasis and a number of other pathologies, including arthritis, infertility and the inability to bear a child.

Before starting treatment, you need to undergo the necessary diagnostic measures. More about them later.

Diagnosis procedure

In many clinical cases Diagnosis of ureaplasmosis causes certain difficulties. The bottom line is that the infectious agent has a conditional “permission” to remain part of the natural microflora female vagina. That is, for example, if during any gynecological or other examination ureaplasma was detected in the patient’s material, this is not 100% evidence of the presence of the disease being studied today.

To make a diagnosis, the doctor must first of all determine the number of opportunistic microorganisms in the organs of the genitourinary system and, based on the results of such a study, draw conclusions about the existing risks.

The beginning of the examination is always the same.

  • identification of symptoms indicating the presence of acute or chronic infectious and inflammatory processes;
  • pregnancy pathologies, history of infertility;
  • previous sex with an infected partner.

Traditionally, general clinical tests, as well as smears (bacterioscopy), culture (the presence of pathogenic microflora is determined and, if necessary, its sensitivity to various antibiotics is studied) and PCR (the DNA of the pathogen is detected).

Additionally, the patient may be prescribed tests for mycoplasmosis, chlamydia, hepatitis and other diseases transmitted through sexual contact.

The most reliable diagnostic method is PCR. This analysis allows you to detect the presence of DNA of pathogenic microorganisms in the material under study. The accuracy of the method approaches 100% and allows you to detect even single pathogen cells. Thus, using PCR, it is possible to confirm the presence of ureaplasmosis even at the stage of the incubation period and in the case of a latent course in the absence characteristic symptoms and signs.

Along with this, for PCR to give the expected results, the analysis must be taken and performed qualified specialists in compliance with established rules and requirements.

The possibility cannot be ruled out false positive results research. These may be present in the following situations:

  • when the test material is contaminated;
  • if the analysis is carried out shortly after treatment for ureaplasmosis. In this case, the study will indicate the presence of pathogenic microorganisms of interest, but with a high degree of probability they will already be dead and harmless;
  • in case of unsuccessful collection of material for research;
  • in case of taking material during the first month after treatment with antibiotics, performing douching, using suppositories;
  • if the rules for taking the test are violated: at least 1 hour must pass between the last urination and the collection of the material.

Despite the high efficiency and reliability of research using the PCR method, it is wrong to limit ourselves to this analysis alone. It is better to undergo a comprehensive examination. If questionable results are obtained, the doctor may refer you for repeat tests.

In addition to identifying the DNA of the causative agent of the disease, the specialist must assess the characteristics of the immune response human body on the activity of pathogenic bacteria. For this purpose, serological diagnostic measures, for example, ELISA, are traditionally used.

If ureaplasma is detected in the body in the absence of symptoms of ureaplasmosis, further diagnostics will be recommended. As a rule, a culture is done. This method is characterized by high accuracy and reliability. The point is this: material (smear) is taken for analysis, then placed in a nutrient medium and the characteristics of growth and development are assessed.

As noted, for the most accurate diagnosis of the disease being studied, it is necessary to know such a parameter as the amount of ureaplasma in the body, and it is culture that allows such an assessment.

To determine the characteristics of the pathogen’s response to medications, an antibiogram is performed. Based on the results, the specialist will be able to develop the most effective treatment program for a particular case, because Ureaplasmas react differently to exposure to various antibacterial drugs.

Treatment methods

Remember the main rule: in the case of ureaplasmosis, other diseases of the genitourinary system, and any diseases in general, uncontrolled self-medication is an unforgivable mistake - only with a competent and qualified approach can you count on positive results, otherwise the situation may only get worse.

Antibiotics are used to treat ureaplasmosis. Specific drugs, their dosages and features of use are determined by the doctor on an individual basis. As a rule, not only tablets are prescribed, but also means for insertion into the vagina - douching or suppositories. In advanced cases, drugs for intravenous administration can be used.

Antibacterial therapy is recommended to be combined with the use of immunomodulators. Additionally, eubiotics are involved. The use of these reduces the risk of violation normal microflora body. If ureaplasmosis is detected in a pregnant woman, treatment, as a rule, begins no earlier than 22-23 weeks.

The average duration of therapy is 2 weeks, sometimes less. During treatment, the patient must follow a healthy diet, not drink alcohol, and not have sex. At the same time, not only the infected woman, but also each of her partners should be treated.

Upon completion of the therapeutic course, a control examination is prescribed. Based on the results, the doctor draws conclusions about the effectiveness of the treatment received and the likelihood of ureaplasmosis returning in the future. For control, as a rule, methods such as culture or PCR are used. Re-examination is usually scheduled several weeks after completion of treatment. Women are strongly advised to undergo new tests for at least 3 menstrual cycles.

If the results of a repeat examination reveal ureaplasmosis again, the tests will have to be retaken. If the new results are positive, the doctor will prescribe repeat course treatment. And only after each control (and, as noted, there are at least three in total) shows negative results, it will be possible to calm down and draw conclusions about the woman’s cure.

Among the bacteria that are causative agents of sexually transmitted diseases, gynecologists named ureaplasma as one of the most common. It belongs to the group of opportunistic microorganisms present in the natural microflora of the genitals, and the degree of its danger has not yet been determined. Is it necessary to start treatment if it was detected in a woman, and how does it manifest itself?

What is ureaplasma

A genus of bacteria belonging to the family Mycoplasmataceae and the order Mycoplasmas (single-celled microorganisms that are the simplest of those that reproduce independently) - this is the definition in official medicine give ureaplasma. A little more than half a century ago (in 1954), the bacterium Ureaplasma urealyticum was isolated from a patient suffering from nongonococcal urethritis (inflammation of the urethra). Some characteristics of this microorganism:

The disease that this microorganism causes is called “ureaplasmosis” (one of the types of mycoplasmosis). It has been diagnosed in some women suffering from infertility and chronic problems urogenital area, but ureaplasmosis was not included in the current International Classification of Diseases (ICD-10). The manifestation of pathological activity of ureaplasma can lead to damage to the cervix, prostate gland, urethra (urethra), and may be accompanied by the following diseases:

  • adnexitis (inflammatory process in the appendages);
  • colpitis;
  • cervicitis;
  • cervical erosion;
  • endometritis;
  • pyelonephritis;
  • vaginitis;
  • gonorrhea;
  • chlamydia.

Mechanism of disease development

The pathogenesis of ureaplasmosis is based on adhesive-invasive properties (the ability to overcome the membrane barrier and attach or adhere to a surface) and enzyme-forming properties. Thanks to them, the bacterium that entered the genitourinary organs:

  1. Clings to the cylindrical epithelium located on the mucosa (attaches to its cells).
  2. Merges with cell membrane and due to this, it is able to penetrate the cytoplasm: the internal liquid environment of the cell.
  3. Begins the process of reproduction and production of an enzyme that has the ability to break down immunoglobulin A.

Against the background of what is happening (a decrease in the number of immunoglobulins of a particular group), the body’s defenses are reduced, and the immune response to the activity of infectious agents weakens. If the activity of ureaplasma, which has received pathogenic status, is low, the disease is asymptomatic, the inflammatory process is sluggish, and destructive changes are minimal. With high activity of the bacterium (against the background of accompanying factors), the symptoms of ureaplasmosis appear, because:

  • tissue permeability increases;
  • the vascular reaction increases;
  • epithelial cells begin to break down.

Is it necessary to treat ureaplasma?

The hostility of the microorganism for a healthy person (when ureaplasma in women is opportunistic) in modern medicine continues to be discussed. Doctors detect the bacterium in 60% of adults without pathological processes in the body, and in 30% of newborns, but it can remain in a non-dangerous state for years. If the microflora of the vagina and urinary tract is normal, this is a sufficient protective barrier that prevents inflammation. If symptoms of ureaplasmosis appear, you need to attend to the issue of treatment.

Causes of manifestation

Like most other bacteria that are opportunistic in nature, ureaplasma is present among the natural microflora of the genital organs and urinary tract in 70% of women. Doctors diagnose it in every 3rd newborn and even in schoolgirls who are not sexually active (more than 20% of teenage girls), but it makes itself felt only in in rare cases. The development of ureaplasmosis begins only against the background of the appearance of certain factors that transform an opportunistic microorganism into an infectious agent:

  • Hormonal imbalances are the primary cause of the development of ureaplasmosis in pregnant women entering menopause and taking hormone-based medications. No less important point are diseases endocrine system, especially related to the functioning of the ovaries.
  • Decreased immunity – both due to the use of immunosuppressants (drugs that suppress the body’s defenses: prescribed for the treatment of oncology), and against the background of infectious viral or bacterial diseases: influenza, ARVI, etc.
  • Vaginal dysbiosis - a violation of the natural microflora of the vagina, gynecologists associate mainly with an imbalance hormonal levels, sexually transmitted infections, violation of intimate hygiene rules. This situation provokes the activity of all opportunistic microorganisms, so candidiasis (thrush) may appear with ureaplasmosis.
  • Invasive interventions - danger is posed not only by abortion (mainly the curettage procedure), but also by the therapeutic and diagnostic manipulations of a gynecologist: urethroscopy, hysteroscopy, cystoscopy, surgical intervention with cervical erosion.
  • Frequent change of sexual partners - unprotected sex and constant appearance casual sexual partners leads to the introduction of infectious agents into the vagina, which provokes the activation of ureaplasma and other opportunistic microorganisms against the background general changes microflora.

Transmission routes

Ureaplasma occurs much more often in women than in men (they have a tendency to self-heal), so they are considered the main carriers of the infection. Among all transmission routes, sexual is the leading one - among all infected people, about 80% are people who have sexual contacts, especially without a regular partner. Transmission of the causative agent of ureaplasmosis is possible both during unprotected vaginal intercourse and during oral intercourse. Bacteria present:

  • in women - in the secretion of the cervical canal, vagina;
  • in men - in prostate secretions, urethra, sperm.

Some doctors suggest the possibility of infection through household contact: through personal hygiene items of the patient, but the theory has not yet been properly confirmed. It is almost impossible to become infected in a bathhouse, swimming pool and other public places. In addition, there are several other ways that are relevant for childhood infection:

  • During childbirth, when passing through the birth canal, small children become infected (30% of newborn girls get ureaplasmosis), even if the mother does not experience symptoms of ureaplasmosis.
  • Through amniotic fluid(in utero through the placenta) - bacteria will be found in oral cavity, nasopharynx, conjunctiva. Infection mainly occurs in the 1st trimester of pregnancy, when the disease worsens in the mother.

Types of ureaplasma in women

There are several ways to classify this disease: according to the severity of its manifestations, it is often divided into asymptomatic carriage and an active inflammatory process (typical of other forms). The duration of ureaplasmosis is:

  • Early - divided into sluggish (erased symptoms, can be observed in the incubation period - 2-4 weeks), acute (bright pronounced manifestations, may be accompanied by severe intoxication; lasts 1-2 months, affects mainly the urinary system), subacute (transitional stage to chronic).
  • Chronic - appears 2 months after the development of any of the previous forms. The organs of the reproductive system may be affected. Mostly it looks similar to carriage, but is periodically accompanied by relapses, manifesting itself as an acute form. Stress factors are often the catalyst.

Carriage

The most common option is when ureaplasma is present in women’s bodies, but does not manifest itself at all. Carriage in the absence of risk factors may never make itself felt, as in the case of a latent (hidden) course of the disease, but the bacterium is transmitted to a sexual partner. As soon as immunity decreases, a stressful situation occurs, hormonal levels become unstable, a woman may experience erased symptoms (rare mucous discharge, vaginal itching), but the general condition will remain normal, and the described manifestations will quickly disappear on their own.

Acute ureaplasmosis

If sexually transmitted infection occurs, it will manifest itself after the incubation period. acute stage infection, which in its clinical picture is similar to the manifestations of other sexually transmitted diseases. They may suffer from frequent urge to urinate (the process is uncomfortable), pain in the lower abdomen, discomfort during sexual intercourse, and a slight rise in temperature. Symptoms persist for no longer than 2 months.

Chronic

Symptoms at this stage may be absent, but if the bacterium is not active during carriage, then during the chronic course of the disease its pathological activity is hidden. Transfer from acute form to chronic it takes 1.5-2 months. From time to time, a woman may experience relapses or develop complications in the organs of the urinary system, resulting in:

  • mucous discharge mixed with bloody discharge;
  • pain in the lower abdomen, radiating to the lower back;
  • symptoms of cystitis (impaired urination with inflammation of the bladder).

Symptoms and signs of the disease

How activated ureaplasma will manifest itself in women depends on several points: the general condition of the body, the presence additional diseases(especially sexually transmitted diseases - diseases that provoke chlamydia, gonococcus and other bacteria), and even routes of infection. So, women who get the disease during oral sex will experience signs of sore throat and pharyngitis. Mostly the symptoms are:

  • vaginal discharge (from weak transparent to cloudy yellowish and even bloody);
  • discomfort or pain when urinating and increased urge to urinate;
  • cutting pains in the lower abdomen (if endometritis, adnexitis are associated);
  • vaginal pain during sexual intercourse;
  • weakness, increased fatigue;
  • low-grade fever.

The main symptoms of ureaplasma in women are similar to those that appear during other inflammatory diseases of the genitourinary system, which complicates the process of independent home diagnosis. If the transmission of a pathogenic microorganism occurs during sexual intercourse, symptoms will begin to appear after 2-4 weeks (incubation period), but often (more than 70% of cases) even the disease that begins in a woman does not make itself felt.

Why is ureaplasmosis dangerous in women?

The mere presence of an opportunistic bacteria in the body is not a cause for concern, but microorganisms settled on the walls of the vagina, uterus, and bladder can be activated at any time when one of the factors described above appears. The result will be the development of the disease, which, in the absence of timely and proper treatment will develop into a chronic form. Relapses will begin against the background:

  • colds;
  • hypothermia;
  • third-party inflammatory processes;
  • stressful situations;
  • active alcohol consumption;
  • heavy physical activity;
  • other reasons for decreased immunity.

The main consequence is a general deterioration in the woman’s condition, against the background of which the body temperature may rise, but this is not why ureaplasmosis becomes dangerous. Against the background of a chronic inflammatory process caused by ureaplasmas in the body (mainly in reproductive system and urinary) concomitant diseases and pathologies develop:

  • inflammatory process in the kidneys (pyelonephritis);
  • pain during sexual intercourse;
  • inflammatory process in the bladder (cystitis);
  • formation of adhesions in fallopian tubes;
  • inflammatory processes in the joints;
  • narrowing of the urethra (urethra);
  • inflammatory process on the walls of the uterus (endometritis), in the appendages or in other areas;
  • the appearance of stones in the kidneys or bladder;
  • inflammation of the vagina (colpitis);
  • menstrual irregularities;
  • infertility (due to the permanent inflammatory process, it is equally possible in women and men - the latter receive an infection during sexual intercourse from a sick woman).

Ureaplasma infection during pregnancy

Gynecologists advise a woman who is planning to give birth to a child to be examined for the presence of ureplasma, since during pregnancy the risk of its activation is especially high. Even a small amount of these bacteria, which are in a conditionally pathogenic state, can lead to the development of ureaplasmosis - due to fluctuations in hormonal levels and a natural decrease in immunity. There are several reasons for examination and treatment before pregnancy:

  • In the 1st trimester, it is prohibited to use antibiotics (they are the only strong medicine against ureaplasma), since such therapy will negatively affect the development of the fetus. As a result, the active development of the disease will begin, which is especially dangerous for the baby in the first weeks - from the 2nd trimester he is less vulnerable.
  • Severe inflammation associated with autoimmune processes in the endometrium can cause primary placental and secondary fetoplacental insufficiency: conditions in which morphofunctional disorders occur in the placenta. The result is problems with fetal development (with an increased risk of anomalies), up to the appearance of diseases in the fetus. perinatal period.
  • The most terrible consequence of ureaplasmosis in a woman bearing a child at any stage is not only premature birth, but also termination of pregnancy due to miscarriage.

Diagnostics and identification of the pathogen

Doctors say that the diagnosis is not made based on the presence of ureaplasma in the body - the more important point is the number of these microorganisms and the mass of their spread throughout the genitourinary system. The symptoms that the patient complains about are necessarily taken into account, but the basis is laboratory and instrumental diagnostic methods. The check must be comprehensive, especially in the presence of concomitant diseases, and includes:

  • Bacterial culture for ureaplasma (culture test) - inoculation of biomaterial (for women, a smear and vaginal discharge is used) on a nutrient medium, as a result of which it is possible to isolate bacterial colonies and subsequently determine their resistance to specific antibiotics.
  • PCR diagnostics (polymerase chain reaction) - helps to track the DNA molecules of infection present in the body. This is done by taking a smear. This analysis is highly accurate; after the end of treatment, 3 weeks later it can be re-administered to check the quality of the therapeutic measures taken.
  • Serological testing is considered the most significant for women suffering from infertility or having diseases that are on the list of potential complications of ureaplasmosis. It consists of ELISA (enzyme-linked immunosorbent assay) and RIF (immunofluorescence reaction) tests. They are aimed at identifying antigens to the cellular composition of the walls of a given bacterium; a smear is taken to conduct them.

Treatment regimen for ureaplasma in women

According to official medical statistics, when diagnosing ureaplasma in women, it is found together with mycoplasma and chlamydia, therefore several types of antibiotics are included in the treatment regimen. The doctor must select specific therapeutic methods, but an approximate course is as follows:

  1. Impact on the pathogen - this is done by antibiotics selected for a specific microorganism through bacterial culture.
  2. Elimination of concomitant diseases of the genitourinary system (groups of medications and procedures depend on the specific problem).
  3. Local infection control using suppositories that have antiseptic or antibacterial properties.
  4. Restoration of the bacterial microflora of the intestines and vagina after treatment with antibiotics (probiotics are used, mainly on lactobacilli).
  5. Strengthening the immune system with immunostimulants/immunomodulators, vitamins and mineral complexes.
  6. Replay tests after 2-3 weeks to check the effectiveness of treatment.

Additionally, a diet that is relevant for all stages of treatment must be added here: excluded fatty food, salty, spicy. The woman is advised to limit sexual intercourse and, if necessary, sanitize the vagina. In some situations, doctors advise undergoing a course of physiotherapy, which eliminates unpleasant symptoms and improves penetration medicines locally.

Etiotropic antibiotic therapy

Drugs that help stop the proliferation of a pathogenic microorganism and kill it are selected during diagnostic examination, which helps to establish the sensitivity of ureaplasma to specific antibacterial substances. Self-prescription of such medications is unacceptable! Treatment lasts 1-2 weeks. The following groups of antibiotics can influence ureaplasmosis:

  • Macrolides (Josamycin, Midecamycin, Clarithromycin, Azithromycin) are relatively safe, can be used in pregnant women from the 2nd trimester, and have a minimal number of side effects.
  • Tetracycline series (Unidox, Doxycycline) - prohibited for pregnant women. Ureaplasmas are insensitive to tetracycline in 10% of cases, so it is classified as a reserve substance.
  • Fluoroquinolones (Ofloxacin, Ciprofloxacin, Tsiprolet) are not recommended during pregnancy or cerebral vascular pathologies. Additionally, the fluoroquinolone series increases the sensitivity of the skin to UV rays, so sunbathing during treatment is prohibited.
  • Aminoglycosides (Neomycin, Spectinomycin) are rarely prescribed, but they work at all phases of bacterial development and are effective even in severe forms of the disease.
  • Lincosamines (Dalacin, Clindamycin) are effective against mycoplasma, their principle of action is related to macrolides, and they activate the mechanisms of nonspecific defense of the microorganism.
  • Probiotics - some of them (Bifidumbacterin, Linex) have activity against pathogens, but their main purpose is to normalize the microflora. The advantages include safety of use in pregnant women.

Suppositories for ureaplasma in women

Doctors advise influencing pathogenic microorganisms from all sides, so it’s not superfluous to local application antiseptic and bacterial agents presented in suppository format. They can have a vaginal or rectal purpose and, in addition to influencing the pathogen, have a symptomatic effect: eliminate pain, itching, burning, and minimize inflammation. Predominantly prescribed:

  • Genferon – are an antibacterial and antiviral agent, have an analgesic effect, stimulate local immunity. The composition is combined (interferon, taurine, benzocaine), works systemically. Suppositories are used vaginally 2 times a day, the course of treatment is 10 days (chronic forms of the disease - 1-3 months, but use every other day).
  • Hexicon - prescribed as a weekly course, allowed during pregnancy. Used 1 time/day, vaginally. They work on chlorhexidine, so they only have an antiseptic effect. They do not have a systemic effect and are not used alone.

Immunotherapy

Drugs that increase the body’s defenses have almost no effect on pathogenic microorganisms, but without them, firstly, even after complete cure a new infection is possible. Secondly, they help speed up the healing process because they set the body up to fight on its own. For this purpose use:

  • Immunostimulants – give a boost to the immune system, helping to more actively produce protective cellular components. May be stimulants nonspecific resistance body (Methyluracil), humoral immune reactions(Myelopid), cellular immunity(Timoptin, Timalin). May be of plant or synthetic origin. The safest for pregnant women is Lysozyme, which has additional antibacterial properties.
  • Immunomodulators (Wobenzym, Cycloferon) - are of high importance in autoimmune diseases, adjust the protective system. The function of immunomodulators is performed by probiotics, cytostatics, anti-Rhesus immunoglobulins, hormonal agents and even some antibiotics (cyclosporine, rapamycin).

Taking vitamins and probiotics

Both during etiotropic treatment and after, it is necessary to restore the vaginal microflora (with long-term use antibiotics - and intestines) and take a course of general strengthening vitamin-mineral complexes. Probiotics are used internally and externally, which will help completely suppress the pathological activity of bacteria. Doctors advise using the following drugs:

  • To eliminate intestinal dysbiosis - Linex, Bacteriobalance, Bificol: contain lactobacilli and bifidobacteria.
  • Local vaginal probiotics – Vagisan, Gynoflor, Vagilak, Bifidumbacterin.
  • Vitamin and mineral complexes - Alphabet, Solutab, Biovitrum, Complivit (it is advisable to select them with a doctor, based on the deficiency of specific elements).

Vaginal sanitation

Treatment of ureaplasma in women necessarily involves antiseptic treatment vaginal mucosa (sanitation), which is carried out using any local funds that have this property. The technique makes sense both during treatment and for the prevention of re-infection. For sanitation use:

If the procedure is performed in a clinic, a vacuum or ultrasound method can be used. At home, sanitation is carried out after washing the genitals, the course of treatment lasts 2 weeks. Every day, a woman injects 10 ml of chlorhexidine into the vagina, lying on her back and slightly raising her pelvis. After the procedure, you should not wash your face; you should refrain from urinating for 2.5 hours.

Physiotherapeutic procedures

Doctors call electrophoresis the most useful of all physical therapy options (prescribed for sexually transmitted diseases): it helps to deliver medications locally faster and more reliably. It is especially valuable in chronic inflammatory processes. Additionally, we may recommend:

  • Magnetic therapy - can also involve the administration of drugs, is an effect on the genitals magnetic field.
  • Laser irradiation is the effect of a special laser on the urethra to relieve pain, relieve inflammation, and stimulate local immunity.
  • Exposure to dry heat - has an analgesic effect, increases lymph flow, is especially useful when cystitis occurs. In case of exacerbation, this technique is not used.

Prevention and prognosis

With timely and correctly carried out etiotropic treatment, it is possible to completely destroy the pathogen, but reinfection women are not excluded. Due to the nature of the transmission of infection, a reliable way to protect against it (mainly from an increase in the number of bacteria in the vagina and changes in its microflora) is to use a condom during sexual intercourse, including oral. Additionally, it is advisable to avoid frequent shifts sexual partners and:

  • after accidental sexual intercourse, use local antiseptics (Chlorhexidine, Miramistin);
  • monitor your immunity (take immunostimulants periodically in courses);
  • observe the rules of personal hygiene;
  • undergo a preventive examination by a gynecologist annually;
  • promptly treat diseases of the genitourinary system.

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